Title: Cape Girardeau County Vacation Rentals from CA $191: Short-Term Rentals for 2026 | Expedia.ca

[Cape Girardeau County Hotels](https://expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations)[Cape Girardeau County Car Rentals](https://expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Rental-Destinations)[Cape Girardeau County Vacations](https://expedia.ca/Cape-Girardeau-County.d553248635976430467.Destination-Travel-Guides)

![The hike is well worth this view at the top of Inspiration Point.](https://images.trvl-media.com/place/820/f194d2c0-30cb-4042-92da-43d24696c201.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Jessica King

# Cape Girardeau County Vacation Rentals

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## Top Cities in Cape Girardeau County

![](https://mediaim.expedia.com/destination/2/5b27a574bbd8c4a139204e48a625a1c7.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Cape Girardeau

[](https://expedia.ca/Cape-Girardeau-Vacation-Rentals.d820.Travel-Guide-VacationRentals)

## Our top choices for Cape Girardeau County vacation rentals

![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/327c3e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Urban Lofts

[](https://www.expedia.ca/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information)

Perryville

9.2/10

Wonderful

(17)

"Great place to stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

[](https://www.expedia.ca/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Cape Girardeau County Hotel Reviews

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Breakfast great hot and big variety "

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg)

### Town House Inn

10/10 Excellent

"Everything was excellent and comfortable beds "

[](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Didn’t eat the breakfast but I’m sure it is wonderful. Everything from the Check in process to the condition of the rooms to the comfort of the stay was worth the money "

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Very clean premises, easy check-in, quiet, good breakfast and Wendy, the receptionist was the BEST ever in providing professional, quality and attentive customer service with a smile and warm welcome!"

[](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg)

### Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"Room was clean and spacious."

[](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

![Hampton Inn Cape Girardeau I 55 East](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg)

### Hampton Inn Cape Girardeau I 55 East

10/10 Excellent

"Cleanliest hotel I’ve ever stayed at! Staff was friendly. Room was spacious. Bed was comfortable. I would 100% recommend! Close to the university. Across the street from Starbucks and many other places to eat."

[](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information)

![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"The room was clean and the mattress was extremely comfortable "

[](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"It was amazing check in to check out"

[](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

10/10 Excellent

"Yes"

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

## Find out more about Cape Girardeau County

**Everything you need to know about** **Cape Girardeau County** **vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Cape Girardeau County vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cape Girardeau County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Cape Girardeau County vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Cape Girardeau County. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Cape Girardeau County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. The selection of Cape Girardeau County vacation rentals we have selected for you start as low as CA $191 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Cape Girardeau County rentals**

At Expedia, we put the best Cape Girardeau County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Cape Girardeau County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cape Girardeau County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cape Girardeau County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

## Explore a world of travel with Expedia

- Popular Cape Girardeau County Cities
- All accommodation types in Cape Girardeau County

- [Cape Girardeau Vacation Rentals ](https://expedia.ca/Cape-Girardeau-Vacation-Rentals.d820.Travel-Guide-VacationRentals)

- [Vacation Homes in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Private-Vacation-Homes.d553248635976430467-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cabin Rentals in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Cabins.d553248635976430467-aaCabins.Travel-Guide-Accommodation)
- [Apartments in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Apartments.d553248635976430467-aaApartments.Travel-Guide-Accommodation)
- [Cottages in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Cottages.d553248635976430467-aaCottages.Travel-Guide-Accommodation)
- [Farmstay in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Agritourism.d553248635976430467-aaAgritourism.Travel-Guide-Accommodation)
- [RV Parks in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-RV-Parks.d553248635976430467-aaRVParks.Travel-Guide-Accommodation)
- [Lodges in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Lodges.d553248635976430467-aaLodges.Travel-Guide-Accommodation)
- [B&B in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Bed-And-Breakfast.d553248635976430467-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Motels in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Motels.d553248635976430467-aaMotels.Travel-Guide-Accommodation)
- [Aparthotels in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Apart-Hotels.d553248635976430467-aaApartHotels.Travel-Guide-Accommodation)

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