Book The Best Hotels in Essex, MO for 2026 from CA $71 - Fully Refundable Options

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Our top choices for Essex hotels

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

1. Econo Lodge Dexter

Dexter

Herman

CA $72

CA $81 total

includes taxes & fees

Oct 22 - Oct 23

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

2. Hampton Inn By Hilton Dexter

Dexter

Kendall

CA $137

CA $154 total

includes taxes & fees

Oct 4 - Oct 5

A diner with booth seating, a checkered floor, and a counter with a cash register.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

3. Travelodge by Wyndham Dexter

Dexter

Steven

CA $134

CA $150 total

includes taxes & fees

Oct 1 - Oct 2

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

4. Dexter Inn

Dexter

Edward

CA $90

CA $101 total

includes taxes & fees

Oct 24 - Oct 25

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

5. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

CA $132

CA $152 total

includes taxes & fees

Sep 27 - Sep 28

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

6. Hampton Inn Sikeston

Sikeston

John

CA $143

CA $162 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

7. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

CA $142

CA $161 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

8. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

michael

CA $142

CA $161 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

9. OYO Hickory House Inn

Dexter

Tammy

CA $58

CA $71 total

includes taxes & fees

Sep 24 - Sep 25

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

10. TownePlace Suites by Marriott Sikeston

Sikeston

Stacy

CA $141

CA $159 total

includes taxes & fees

Oct 4 - Oct 5

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

11. Best Western Plus Sikeston I-55

Sikeston

Shelley

CA $123

CA $140 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

12. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Sharika West

CA $89

CA $101 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious lobby with a central atrium, a piano, and a reception desk.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

13. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

CA $93

CA $106 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

14. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

William

CA $80

CA $92 total

includes taxes & fees

Sep 29 - Sep 30

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

A hotel with a central entrance, multiple parking spaces, and a well-lit facade.

A modern kitchen with a stone backsplash, a dining area with red chairs, and a red accent wall with a framed picture.

15. Super 8 By Wyndham Marston

Marston

Rachel

CA $81

CA $92 total

includes taxes & fees

Sep 27 - Sep 28

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

A living room with two sofas, a coffee table, a TV, and a cabinet.

16. Comfort Inn & Suites Sikeston I-55

Sikeston

Starlette

CA $126

CA $143 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a counter, a coffee machine, and seating.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

17. Country Yard Inn and Suite

Sikeston

William

CA $80

CA $95 total

includes taxes & fees

Oct 3 - Oct 4

A hotel room with two beds, a television, a desk, and a mirror.

A bathroom with a sink, mirror, and chair.

A Travel Inn with a parking lot and two vehicles parked in front.

A covered pavilion with a roof, wooden railing, and a barbecue grill.

18. Travel Inn Marston I-55 by Hotel O

Marston

Frank

CA $59

CA $71 total

includes taxes & fees

Sep 25 - Sep 26

A bedroom with a bed, bedside table, lamp, and a view of the bathroom.

A reception desk with a pet fee sign, no smoking sign, and a pet bell sign.

A covered outdoor area with brick walls, windows, and a seating area with a chair and a trash can.

A hallway with vending machines, including a Pepsi and a Coca-Cola machine, and a door at the end.

19. OYO Malden Airport Inn

Malden

James

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Top Essex Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"The hall ways smelled so good but we did get dirty blankets . They have many restaurants and stores options really closed by so if you have children it is a great spot to stop specifically since is just in the entry or exit of the hwy ."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"."

Hampton Inn Sikeston

10/10 Excellent

"Staff was great"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."

Hampton Inn By Hilton Dexter

8/10 Good

"Very nice hotel - our favorite when we visit the grandkids! Our only issue this time was with housekeeping. We arrived Friday afternoon, asked that our room be serviced on Sunday, (they only do it every other day), and it was not done. Also, in the shower were the usual shampoo and shower gel, but instead of conditioner, the 3rd dispenser was body lotion! I asked if the lotion could be replaced with conditioner - didn’t happen. Disappointed!"

OYO Hickory House Inn

10/10 Excellent

"Nice for overnight stop"

Travel Inn Marston I-55 by Hotel O

8/10 Good

"Worked for the price. Room was clean. Staff was friendly! "