Find Spa Hotels in Cape Girardeau, MO from CA $159

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Check availability on Cape Girardeau Spa Hotels

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Mar 21 - Mar 22
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Mar 22 - Mar 23
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Mar 27 - Mar 29
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Apr 3 - Apr 5

Our top choices for Cape Girardeau hotels with a spa

Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
The price is CA $141
CA $159 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Cape Girardeau

Pool
Breakfast included

Find out more about Cape Girardeau

Top Cape Girardeau attractions for a relaxing vacation

In Cape Girardeau, Missouri, travellers seeking spa hotel experiences can indulge in both relaxation and adventure. Begin your exploration at the tranquil Cape Riverfront Park, where scenic walking trails wind along the Mississippi River, providing a serene backdrop perfect for unwinding after a day of pampering. For those who appreciate local culture, the Cape Girardeau Conservation Nature Center offers engaging exhibits and trails that immerse you in the area's natural beauty, ideal for a leisurely stroll or a more vigorous hike. Families can enjoy a fun day at the Cape Splash Family Aquatic Center, which boasts thrilling water slides and a lazy river, ensuring a mix of relaxation and excitement. Don't miss the historic downtown area, where charming boutiques and art galleries await, perfect for a leisurely afternoon of shopping and exploring. After a day of activities, you can retreat to one of the hotels near the riverfront, where luxurious spa services and attentive guest care promise a rejuvenating stay. With the perfect blend of relaxation and local charm, Cape Girardeau offers a unique opportunity to recharge while enjoying its vibrant community.

Find the best hotels & resorts with spas in Cape Girardeau

For those seeking relaxation and rejuvenation during their stay in Cape Girardeau, these hotels offer exceptional spa amenities that will enhance your experience.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

  • Why it's great for tailored spa getaway: The Holiday Inn Express Hotel & Suites Cape Girardeau is an excellent choice for travelers looking to unwind in a serene environment, featuring a full-service spa that promises a refreshing escape from daily stress. With a remarkable guest review rating of 9.4, this hotel ensures that relaxation is at the forefront of your stay. The spa facilities allow guests to indulge in soothing treatments, making it an ideal retreat after a day of exploring the area.
  • Other amenities: In addition to the spa, guests can enjoy a range of conveniences including a complimentary breakfast to kickstart your day, an inviting indoor pool perfect for a refreshing dip, and fitness facilities for those looking to stay active. Each room is equipped with premium bedding, a microwave, and daily housekeeping to enhance comfort. Free self-parking is available, ensuring a straightforward arrival and departure, while the hotel also offers pool sun loungers for leisurely afternoons.
  • Nearby attractions: Saint Francis Healthcare System - 3.9 km, Cape Splash Family Aquatic Center - 3.8 km

Top Cape Girardeau Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

8/10 Good
"Beds were clean and well made however carpet in room was stained. There was a chicken nugget on the floor in the elevator upon arrival and was still there the next morning. Breakfast was good except for preparer wiping her nose with her plastic serving gloves on. Good coffee and easy check in."
Kent 1-night trip
Posted 14 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Amazing stay all around "
Guadalupe 2-night trip
Posted 1 day ago
Drury Inn & Suites Cape Girardeau

Frequently asked questions

Which hotels in Cape Girardeau offer the best spa experiences?
For those seeking spa experiences in Cape Girardeau, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers a full-service spa.

This hotel has a 9.4 rating, and its spa provides a range of treatments for relaxation and rejuvenation. Guests can expect a dedicated space for wellness therapies.
How much does a spa hotel in Cape Girardeau cost?
Enjoy staying in a spa hotel in Cape Girardeau, with plenty of hotels from CA $159 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in Cape Girardeau with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.
Are there any unique spa experiences available in Cape Girardeau?
Yes, Cape Girardeau, Missouri offers several unique spa experiences that blend medical aesthetics, wellness, and traditional spa services.

Dawn of Life Aesthetics & Wellness Med Spa provides an extensive approach, including medical spa treatments such as microneedling, laser hair removal, facials, and IV therapy. They also offer unique functional medicine services like blood testing, gut testing, food sensitivity testing, lymphatic therapy, and hormone testing, blending aesthetics, weight management, and functional medicine.

eDen Spa & Salon is highly rated for its personalised services, including aromatic hot stone massages, facials, pedicures, and couples massages, and is known for its excellent customer care and attention to detail.

West Em Medical Spa offers upscale medical spa services with a focus on customised skin health plans, advanced treatments like BBL and Halo laser procedures, all within an inviting space.

Roots Spa & Salon focuses on health-conscious beauty and wellness, utilising organic and natural products for chemical-free treatments in a peaceful environment.

Aurora Medical Spa offers non-surgical body contouring, long-lasting injectable treatments for wrinkle reduction, and personalised aesthetic plans, focusing on cosmetic outcomes with zero downtime.
How can I save on a spa hotel in Cape Girardeau with Expedia?
Members always get our best prices. Find our best Cape Girardeau spa hotel deals by joining Expedia's free travel rewards program—One Key™. As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Cape Girardeau for you.

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