A city square with a fountain, modern buildings, and a historic tower.

Missouri Spa Resorts

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in Missouri

A large neoclassical building with a prominent dome and columns, a fountain, and well-maintained greenery.
HotelsHotels

Columbia

Columbia

Check availability on Missouri Spa Hotels

This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Missouri hotels with a spa

A spa area with wicker loungers, a stone wall, and a pool.

1. The Elms Hotel & Spa, a Destination by Hyatt Hotel

The Elms Hotel & Spa, a Destination by Hyatt Hotel
4.0 star property
Excelsior Springs
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Immerse in a rejuvenating spa retreat with 17 treatment rooms, hot tubs, and beautiful garden views at this historic hotel.
The price is CA $211
CA $289 total
includes taxes & fees
Oct 29 - Oct 30
The Elms Hotel & Spa, a Destination by Hyatt Hotel
A hotel room with two beds, a nightstand, a cabinet, and a wall-mounted artwork.

2. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
4.0 star property
Lake Ozark
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
The price is CA $124
CA $187 total
includes taxes & fees
Oct 19 - Oct 20
Camden on the Lake Resort & Spa
A couple relaxing by a window overlooking a bridge and water.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is CA $532
CA $622 total
includes taxes & fees
Oct 8 - Oct 9
Four Seasons Hotel St Louis
A thatched-roof building with a sign reading "TIKI HUT POOL BAR".

4. Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
3.0 star property
Osage Beach
8.4 out of 10, Very good, (1,000 reviews)
  • cleanliness
    Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
The price is CA $218
CA $263 total
includes taxes & fees
Oct 28 - Oct 29
Margaritaville Lake Resort Lake of the Ozarks
A swimming pool with a tiled edge, a handrail, and a 'No Standing, No Jumping, No Sitting' sign.

5. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $196
CA $226 total
includes taxes & fees
Oct 15 - Oct 16
Embassy Suites by Hilton St. Louis St. Charles
A rooftop terrace with rows of metal chairs and a view of city buildings.

6. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.6 out of 10, Exceptional, (3,786 reviews)
The price is CA $191
CA $224 total
includes taxes & fees
Oct 8 - Oct 9
Drury Plaza Hotel St. Louis at the Arch
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

7. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,309 reviews)
The price is CA $190
CA $224 total
includes taxes & fees
Oct 3 - Oct 4
Hyatt Regency St. Louis at The Arch
A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

8. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $162
CA $190 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

9. Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1,002 reviews)
The price is CA $179
CA $206 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites St. Louis Arnold
A hotel lobby with seating areas, a fireplace, and a kitchen in the background.

10. Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Riverport
7.8 out of 10, Good, (1,000 reviews)
The price is CA $95
CA $110 total
includes taxes & fees
Oct 12 - Oct 13
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Missouri Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Breakfast was amazing. Great!"
Michael 10-night trip
Posted 4 hours ago
Drury Plaza Hotel St. Louis Union Station

Explore a world of travel with Expedia