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Featured St. Louis Luxury Hotels

See all 322 Hotels in St. Louis
The Chase Park Plaza Royal Sonesta St. Louis

The Chase Park Plaza Royal Sonesta St. Louis

212 N Kingshighway, St. Louis
5.0 out of 5.0
4.4 out of 5 (1,623 reviews)
Very clean and functional.The room was very clean and all of the items we used were functional and usable. We did not encounter any negatives at all.
  30 Dec 2017

C$148

C$148
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles
5.0 out of 5.0
4.5 out of 5 (1,074 reviews)
Loved the room. Very easy check in and free valet !!
  10 Jan 2018

C$166

C$166
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis
4.5 out of 5.0
4.6 out of 5 (336 reviews)
Great overall service and experience. Staff are alway very friendly and helpful.
  17 Jan 2018

C$274

C$274
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis
5.0 out of 5.0
4.8 out of 5 (368 reviews)
Beautiful hotel with accommodating staffNicole and other staff went above and beyond to make our stay luxurious and carefree. Sending kids amenities to the room, my children thought the Hotel was the best part of our vacation!
  30 Dec 2017

C$208

C$208
Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis
3.5 out of 5.0
4.1 out of 5 (3,005 reviews)
Mini fancy hotel It’s like a mini fancy hotel. Small but super glitzy cute entrance Staff was nice andnrooms were very clean. Beds are pretty comfy. 8 min drive from Wash U so it was perfect. Great especially for the price
  15 Jan 2018

C$124

C$124
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis
5.0 out of 5.0
4.6 out of 5 (3,202 reviews)
comfortableWe love staying here as it is such a relaxing place and the staff is so friendly
  5 Jan 2018

C$137

C$137
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis
3.5 out of 5.0
4.6 out of 5 (3,093 reviews)
Friendly staff. Easy access to parking. Everything about this hotel was wonderful. Easy check in. Everyone was friendly. Excellent rooms. Very clean.
  16 Jan 2018

C$149

C$149
Airport Plaza Inn & Conference Center

Airport Plaza Inn & Conference Center

4530 N Lindbergh Boulevard, Bridgeton
3.5 out of 5.0
3.1 out of 5 (1,826 reviews)
Close to Lambert Airport with excellent shuttle!! Our 3rd year staying at this hotel. It is under new ownership, I highly recommend this facility. Friendly staff clean rooms fast shuttle service to and from airport. Only disappointment was they have started to charge for parking in the covered parking garage.
  17 Jan 2018
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis
4.5 out of 5.0
4.4 out of 5 (772 reviews)
Wonderful Boutique-like Hotel Classy and Warm describes the staff and hotel. Rooms are clean, very well thought out and bed was very comfortable. Fitness suite had a large layout with a larger than average assortment of equipment that was well maintained. Breakfast at the Bar/Restaurant named Robies was fantastic! No doubt I ...
  17 Jan 2018

C$125

C$125
Moonrise Hotel

Moonrise Hotel

6177 Delmar Blvd, St. Louis
4.0 out of 5.0
4.7 out of 5 (1,669 reviews)
Always my first choice in the LouWhen I have to be in the Lou( usually 3-4 times a year ) I always stay at the Moonrise. The staff and amenities are second to none. The restaurant isn’t afraid of spicing things up and truly understands that most of its guests are tired and seeking a bit of comfort in their dining. As a professional ...
  15 Jan 2018

C$163

C$163
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When you'll take your luxury hotel with a side of exciting city life, you've found your niche in St. Louis. As one of the most intriguing travel stops for people who want to soak up the energy of a big city, St. Louis always impresses. Exquisite eats, intriguing sites, and some of the world’s most stunning photo opportunities: these are just some of the reasons to take a trip to St. Louis. Of course, you'll stay at a luxury hotel! Sampling the finer things in life is just your speed. While you're here, you'll also enjoy the most popular performances, devour fabulous food, and marvel at the most popular monuments and landmarks . Book your elegant hotel in St. Louis on Expedia.com today and start your vacation off on the right (well-dressed) foot.

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Luxury Hotels in St. Louis

It's that time; you're ready to get swept away in The Gateway to the West, and Expedia.com is here to save the day. Search through the wealth of real traveler reviews on dozens of hotels and then book your ideal room in minutes. 5-Star hotels treat you right, offering things like concierge services and private fireplaces. Many 5-star accommodations in St. Louis even feature gigantic suites, and it's not uncommon to find reinvigorating spa treatments in your hotel. Use our easy booking widget to choose the ideal 5-star hotel in St. Louis, and prepare for the trip of a lifetime!