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Featured St. Louis Luxury Hotels

See all 286 Hotels in St. Louis
The Chase Park Plaza Royal Sonesta St. Louis

The Chase Park Plaza Royal Sonesta St. Louis

212 N Kingshighway, St. Louis
4.5 out of 5.0
4.4 out of 5 (1,606 reviews)
Comfy Double Queen in great locationThe room was large, the beds were incredibly comfortable, the bathroom was expansive and very nice (especially for 3 ladies sharing it). The biew of Forest Park was lovely, the Cinema was neat downstairs and it was in walking distance to a bunch of great food & Shopping. I recommend Dressel's Pub ...
  15 Nov 2017

C$189

C$189
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis
4.5 out of 5.0
4.6 out of 5 (326 reviews)
Standard Ritz Layout. Staff great.The hotel is standard Ritz layout and style. The place is a bit aged and could use a bit of renovation.The staff are excellent. Always attentive, but never underfoot. Range of services and facilities are excellent.
  16 Oct 2017

C$343

C$343
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles
4.5 out of 5.0
4.5 out of 5 (1,042 reviews)
Very nice hotel to stay in!It was a great port in the storm from the traffic on I-70 and all the other roads. You just want to spend your whole vacation in your room!
  17 Oct 2017

C$171

C$171
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis
5.0 out of 5.0
4.8 out of 5 (352 reviews)
Beautiful hotel, great staff, clean comfortable I can't speak a lot about my experience because I had an accident at the airport and stayed in my room recuperating when I should have been enjoying the sights.
  6 Nov 2017

C$212

C$212
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis
4.5 out of 5.0
4.6 out of 5 (3,162 reviews)
Westin I liked the location and how clean the room was.
  22 Sep 2017

C$114

C$114
The Wildwood Hotel

The Wildwood Hotel

2801 Fountain Pl, Wildwood
3.5 out of 5.0
4.5 out of 5 (2,366 reviews)
Nice hotel, nice locationEverything was great to hotel, great staff to deal with. Only disappointment was cleanliness of bathroom. Under seat was dirty and wall of shower had someone else’s long hair stuck on it 😖. Housekeeping needed to do a better job. When there is obvious, visible soiled areas, it makes one question ...
  16 Nov 2017

C$105

C$105
The Cheshire

The Cheshire

6300 Clayton Rd, Richmond Heights
4.0 out of 5.0
4.2 out of 5 (1,353 reviews)
Hotel was clever and convenient for all of the planned wedding activities.
  1 Nov 2017

C$166

C$166
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis
4.0 out of 5.0
4.4 out of 5 (745 reviews)
It was a very beautiful hotel, but the room size did feel like a New York stay.
  3 Nov 2017

C$139

C$139
Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis
3.5 out of 5.0
4.1 out of 5 (2,915 reviews)
2nd stay at this hotelCheck-in was easy and we were able to check-in before their regular check time 3pm. Room was comfortable and clean. Hotel staff was courteous and helpful. There is construction being done in the parking garage that is attached to the hotel but, it wasn't any inconvenience and the noise level was ...
  17 Nov 2017

C$129

C$129
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.0 out of 5.0
4.3 out of 5 (5,594 reviews)
Very nice hotel close where we were working.The only negative I can say is the room next door with the adjoining door I could hear there every word of their conversations. The last night I was there they talked until 1200am.
  17 Nov 2017

C$96

C$96
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When you'll take your luxury hotel with a side of exciting city life, you've found your niche in St. Louis. As one of the most intriguing travel stops for people who want to soak up the energy of a big city, St. Louis always impresses. Exquisite eats, intriguing sites, and some of the world’s most stunning photo opportunities: these are just some of the reasons to take a trip to St. Louis. Of course, you'll stay at a luxury hotel! Sampling the finer things in life is just your speed. While you're here, you'll also enjoy the most popular performances, devour fabulous food, and marvel at the most popular monuments and landmarks . Book your elegant hotel in St. Louis on Expedia.com today and start your vacation off on the right (well-dressed) foot.

Booking St. Louis Vacations

If you need any proof that St. Louis is full of wonderful things to do, you should know that 315,685 people love it enough to have set down roots. No matter what brings you to St. Louis, the destination always delivers. St. Louis is full of outstanding hotels as well as fantastic food, so you can count on a spectacular stay. Book well in advance to get a room with a view!

Any 5-star getaway is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your vacation on Expedia.com, the world is your oyster. Thanks to our hotel deals, you'll still have plenty of cash for the most compelling and captivating adventures. After many hours of seeing the sights, your luxury accommodation awaits. Take advantage of amenities like an oversized bathtub or hot tub before the day is over. The luxury rooms and suites in St. Louis will render you into a state of tranquility in the blink of an eye.

Luxury Hotels in St. Louis

It's that time; you're ready to get swept away in The Gateway to the West, and Expedia.com is here to save the day. Search through the wealth of real traveler reviews on dozens of hotels and then book your ideal room in minutes. 5-Star hotels treat you right, offering things like concierge services and private fireplaces. Many 5-star accommodations in St. Louis even feature gigantic suites, and it's not uncommon to find reinvigorating spa treatments in your hotel. Use our easy booking widget to choose the ideal 5-star hotel in St. Louis, and prepare for the trip of a lifetime!