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Featured St. Louis Luxury Hotels

See all 265 Hotels in St. Louis
The Chase Park Plaza Royal Sonesta St. Louis

The Chase Park Plaza Royal Sonesta St. Louis

212 N Kingshighway, St. Louis
4.5 out of 5.0
4.4 out of 5 (619 reviews)
Central LocationGreeted with kindness from the moment we arrived. The valet staff remembered us from our last stay and immediately accommodated our TEXAS sized vehicle. Check in staff were warm and friendly; bellman attentive. Visited two of the restaurants - easy to adjust menu to fit requests. Excellent food & ...
  11 Sep 2017

C$243

C$243
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis
4.5 out of 5.0
4.6 out of 5 (113 reviews)
Staff here makes the difference. From the moment you arrive you are treated with courtesy and respect. Ask once and iwhatever you want is done. Stately hotel , well appointed. Comfortable in every aspect (common areas, dining rooms and guest rooms. A minor point, but the parking charge for adjacent ...
  4 Sep 2017

C$356

C$356
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles
4.5 out of 5.0
4.5 out of 5 (301 reviews)
Great hotelNice clean hotel with friendly staff. The only complaint I have us that with all the restaurants downstairs and possible leftover takeout, the rooms have a fridge but no microwaves.
  16 Sep 2017

C$163

C$163
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis
5.0 out of 5.0
4.7 out of 5 (98 reviews)
Staff was very friendly and helpful. My wife really enjoyed the facilities at the spa and her treatment. Best hotel in St. Louis.
  11 Sep 2017

C$299

C$299
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis
4.5 out of 5.0
4.6 out of 5 (910 reviews)
Westin I liked the location and how clean the room was.
  22 Sep 2017

C$173

C$173
The Wildwood Hotel, BW Premier Collection

The Wildwood Hotel, BW Premier Collection

2801 Fountain Pl, Wildwood
3.5 out of 5.0
4.4 out of 5 (612 reviews)
Can't wait to come back!My fiance and I stayed at the Wildwood this past Aug for the eclipse. We had such a great experience, we're coming back for our honeymoon! First off, the staff was amazing, Every single person we encountered was warm, friendly, and they seemed genuinely concerned about their guests. Secondly, there's ...
  18 Sep 2017

C$132

C$132
The Cheshire

The Cheshire

6300 Clayton Rd, Richmond Heights
4.0 out of 5.0
4.0 out of 5 (391 reviews)
Enjoyable stay. Very convenient. Staff very helpful. Location very good just adjacent to Forest Park. Nice facility with the best "free" breakfast of any of the hotel in which we have stayed. Easy parking in protected garage. Would stay here again when in the area.
  3 Sep 2017

C$180

C$180
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis
4.0 out of 5.0
4.3 out of 5 (197 reviews)
Beautiful St Louis Hotel The hotel is a beautiful boutique. Our room was very comfortable and quiet. It was a just a short walk to Bush Stadium and may be our new St. Louis regular hotel!
  15 Sep 2017

C$196

C$196
Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis
3.5 out of 5.0
4.0 out of 5 (586 reviews)
Good PropertConfortable stay Hearty breakfast Nice clean rooms
  20 Sep 2017

C$129

C$129
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.0 out of 5.0
4.3 out of 5 (1,639 reviews)
Beale street Make sure you request the right side of hotel depending on your visit. I was only there overnight to fly in the morning. My room was only a few feet from a band stand and the said band and noise from Beale street played until 2 am. Hotel could not move me.
  17 Sep 2017

C$170

C$170
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When you'll take your luxury hotel with a side of exciting city life, you've found your niche in St. Louis. As one of the most intriguing travel stops for people who want to soak up the energy of a big city, St. Louis always impresses. Exquisite eats, intriguing sites, and some of the world’s most stunning photo opportunities: these are just some of the reasons to take a trip to St. Louis. Of course, you'll stay at a luxury hotel! Sampling the finer things in life is just your speed. While you're here, you'll also enjoy the most popular performances, devour fabulous food, and marvel at the most popular monuments and landmarks . Book your elegant hotel in St. Louis on Expedia.com today and start your vacation off on the right (well-dressed) foot.

Booking St. Louis Vacations

If you need any proof that St. Louis is full of wonderful things to do, you should know that 315,685 people love it enough to have set down roots. No matter what brings you to St. Louis, the destination always delivers. St. Louis is full of outstanding hotels as well as fantastic food, so you can count on a spectacular stay. Book well in advance to get a room with a view!

Any 5-star getaway is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your vacation on Expedia.com, the world is your oyster. Thanks to our hotel deals, you'll still have plenty of cash for the most compelling and captivating adventures. After many hours of seeing the sights, your luxury accommodation awaits. Take advantage of amenities like an oversized bathtub or hot tub before the day is over. The luxury rooms and suites in St. Louis will render you into a state of tranquility in the blink of an eye.

Luxury Hotels in St. Louis

It's that time; you're ready to get swept away in The Gateway to the West, and Expedia.com is here to save the day. Search through the wealth of real traveler reviews on dozens of hotels and then book your ideal room in minutes. 5-Star hotels treat you right, offering things like concierge services and private fireplaces. Many 5-star accommodations in St. Louis even feature gigantic suites, and it's not uncommon to find reinvigorating spa treatments in your hotel. Use our easy booking widget to choose the ideal 5-star hotel in St. Louis, and prepare for the trip of a lifetime!