Title: Book the Best St. Louis LUXURY Hotels - Upscale Hotels in St. Louis, MO | Expedia.ca [St. Louis Travel Guide](https://expedia.ca/St-Louis.dx178309)[Hotels in St. Louis](https://expedia.ca/St-Louis-Hotels.d178309.Travel-Guide-Hotels)[Vacation Rentals in St. Louis](https://expedia.ca/St-Louis-Vacation-Rentals.d178309.Travel-Guide-VacationRentals)[Flights to St. Louis](https://expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[St. Louis Car Rentals](https://expedia.ca/Car-Rentals-In-St-Louis.d178309.Car-Rental-Guide)[St. Louis Vacation Packages](https://expedia.ca/St-Louis.d178309.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478475-Saint-Louis.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in St. Louis, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on St. Louis Luxury Hotels Tonight [Oct 28 - Oct 29](https://www.expedia.ca/Hotel-Search?regionId=178309&startDate=2025-10-28&endDate=2025-10-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=178309&startDate=2025-10-29&endDate=2025-10-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=178309&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=178309&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top St. Louis Luxury Hotels ## Find out more about St. Louis ### St. Louis (and vicinity)and its attractions for luxury travelers In the greater St. Louis area, luxury travellers will find an abundance of sophisticated experiences awaiting them. Begin your journey at the iconic Gateway Arch, where you can take a tram ride to the top for breathtaking views of the city skyline and the Mississippi River. Next, indulge in a leisurely afternoon at the Missouri Botanical Garden, a stunning 79-acre oasis that boasts exquisite floral displays and serene landscapes, perfect for a picnic or a peaceful stroll. For art enthusiasts, the Saint Louis Art Museum offers an impressive collection spanning 5,000 years, housed in a beautiful building that is a work of art itself. If you're feeling adventurous, a hot air balloon ride at the nearby Tower Grove Park presents a unique perspective of the area, while an evening stroll through the historic Soulard neighbourhood, known for its vibrant nightlife and exquisite dining options, promises delightful culinary experiences. For accommodation, consider the upscale Central West End, where luxury hotels blend modern amenities with historic charm, providing a perfect base to explore the neighbourhood's chic boutiques and gourmet restaurants. Here, attentive service and lavish comforts ensure you feel truly pampered throughout your stay. ### Find the best luxury hotels and resorts in St. Louis (and vicinity) For those seeking a touch of elegance in St. Louis, these luxurious hotels offer exceptional amenities and experiences that define opulence. [Four Seasons Hotel St Louis](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) - **Why it's great for a luxury retreat:** Four Seasons Hotel St Louis is the epitome of luxury, an impressive guest review rating of 9.4. This stunning hotel offers river views, a poolside bar, and 24-hour room service, catering to every desire of sophisticated travelers seeking a refined experience. - **Other amenities:** The hotel also features a full-service spa with treatment rooms, including massages and body treatments, ensuring relaxation and rejuvenation. Other amenities include valet parking, an outdoor pool, and options for couples dining, creating a romantic atmosphere for guests. Fitness facilities are available 24/7, along with manicures and pedicures, making it an ultimate luxury escape. - **Neighborhood:** Downtown St. Louis - **Nearby attractions:** Mississippi River - 0.6 km, Dome at America’s Center - 0.8 km, Horseshoe St. Louis Casino - 0.1 km [The Wildwood Hotel](https://www.expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) - **Why it's great for a luxury retreat:** The Wildwood Hotel, rated a fantastic 9.2, offers a luxurious retreat with premium bedding and designer toiletries, making it a delightful choice for travelers. The hotel features an inviting indoor pool and a soothing hot tub, perfect for unwinding after a day of exploration. - **Other amenities:** Additional amenities include free breakfast options, accessible van parking, and nearby skiing activities for adventure enthusiasts. Guests can also enjoy the convenience of a kitchenette in select rooms, along with private hot tubs, ensuring a comfortable and enjoyable stay. - **Nearby attractions:** Meramec River - 7.9 km, Wildwood Dog Park - 2.8 km, Dr. Edmund A. Babler Memorial State Park - 6.6 km [Moonrise Hotel](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) - **Why it's great for a luxury retreat:** With a remarkable review rating of 9.0, Moonrise Hotel stands out as a boutique luxury experience in St. Louis' Delmar Loop. Guests can enjoy lavish features such as premium bedding, designer toiletries, and plush bathrobes, creating a truly indulgent atmosphere during their stay. - **Other amenities:** In addition to its luxurious offerings, the hotel provides a 24-hour fitness centre, valet parking, and a picturesque rooftop terrace. Guests can also benefit from daily housekeeping, electric car charging stations, and nearby historical sites, enhancing their overall experience in this vibrant neighbourhood. - **Neighborhood:** Delmar Loop - **Nearby attractions:** Washington University in St. Louis - 1.1 km, Forest Park - 1.1 km, St. Louis Art Museum - 2.1 km [Clayton Plaza Hotel & Extended Stay](https://www.expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) - **Why it's great for a luxury retreat:** A perfect choice for luxury travelers, Clayton Plaza Hotel & Extended Stay boasts an excellent guest review rating of 8.8, making it a popular / top / much-loved option for comfort and style. Guests can indulge in the heated pool and premium bedding, ensuring a restful stay that exudes sophistication and relaxation. - **Other amenities:** In addition to its luxurious amenities, the hotel features an indoor pool, a 24-hour fitness centre, and complimentary breakfast, enhancing the overall guest experience. Visitors can enjoy the convenience of accessible self-parking and nearby golfing options, while the hotel’s arcade game room adds a fun twist to the stay. - **Neighborhood:** Clayton - **Nearby attractions:** Saint Louis Galleria Mall - 2.2 km, Washington University in St. Louis - 3 km [Hyatt Regency St. Louis at The Arch](https://www.expedia.ca/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) - **Why it's great for a luxury retreat:** Hyatt Regency St. Louis at The Arch is an exquisite destination for luxury seekers, receiving a solid review rating of 8.4. This hotel offers club-level rooms that include refreshing lounge access, along with premium bedding and valet parking for an elevated guest experience. - **Other amenities:** Alongside its luxurious accommodations, guests can take advantage of a rooftop terrace, a well-equipped health club, and complimentary toiletries. The hotel also features a business centre, gift shops, and self-parking options, ensuring convenience and comfort throughout their stay. - **Neighborhood:** Downtown St. Louis - **Nearby attractions:** Busch Stadium - 0.9 km, America's Center Convention Complex - 1 km, Dome at America’s Center - 1 km ## Top St. Louis Hotel Reviews ## Frequently asked questions ### Are you searching for a great accommodation for your luxury getaway to St. Louis? > Travel to St. Louis Lambert Intl. Airport (STL) Airport or St. Louis, MO (SUS-Spirit of St. Louis) Airport, and then treat yourself to a stay at one of 7 St. Louis luxury hotels. Known for its art and theater, St. Louis also has some interesting things to see and do including St. Louis Union Station and Busch Stadium, so you may want to take in the local sights during your visit. ### What's the best high-end place to stay in St. Louis? > [21C Museum Hotel St Louis](https://www.expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. [The Royal Sonesta Chase Park Plaza St. Louis](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) and [Four Seasons Hotel St Louis](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) are other upscale choices for your trip. ### How many luxury hotels should I expect to find in St. Louis? > Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 7 luxury hotels. ### When can I expect good weather in St. Louis? > Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for St. Louis is 54 inches. ### What's there to see and do in St. Louis? > Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, Busch Stadium, and Gateway Arch. If you have extra time while you're in the area, you might want to see St. Louis Aquarium at Union Station and Energizer Park. ### How can I get around St. Louis? > It's easier to get around town comfortably when you know your options. 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[Visit Benton Park](https://www.expedia.ca/St-Louis-Benton-Park.dx553248635976008174) - [Visit Compton Heights](https://www.expedia.ca/St-Louis-Compton-Heights.dx6351954) - [Visit Downtown St. Louis](https://www.expedia.ca/St-Louis-Downtown-St-Louis.dx800136) - [Visit Soulard](https://www.expedia.ca/St-Louis-Soulard.dx553248634993813110) - [St. Louis Union Station Mini Golf](https://www.expedia.ca/St-Louis-Union-Station-Mini-Golf-Downtown-West.d621092167072251904.Vacation-Attraction) - [Alamo Rent A Car Rental Cars in Downtown St. Louis](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Downtown-St-Louis.d800136-c6.Car-Rental-Guide-Suppliers) - [Enterprise Rental Cars in Downtown St. Louis](https://www.expedia.ca/Enterprise-Car-Rentals-In-Downtown-St-Louis.d800136-c15.Car-Rental-Guide-Suppliers) - [Book Luxury Hotels in St. Louis on Expedia.com](https://www.expedia.com/St-Louis-Hotels-Luxury-Hotel.0-0-d178309-tLuxuryHotel.Travel-Guide-Filter-Hotels)