Title: Book the Best Osage Beach SPA Resorts from CA $163 - Spa Hotels in Osage Beach, MO | Expedia.ca [Osage Beach Travel Guide](https://expedia.ca/Osage-Beach.dx6058781)[Hotels in Osage Beach](https://expedia.ca/Osage-Beach-Hotels.d6058781.Travel-Guide-Hotels)[Vacation Rentals in Osage Beach](https://expedia.ca/Osage-Beach-Vacation-Rentals.d6058781.Travel-Guide-VacationRentals)[Flights to Osage Beach](https://expedia.ca/Cheap-Flights-To-Osage-Beach.d6058781.Travel-Guide-Flights)[Things to do in Osage Beach](https://expedia.ca/Things-To-Do-In-Osage-Beach.d6058781.Travel-Guide-Activities)[Osage Beach Car Rentals](https://expedia.ca/Car-Rentals-In-Osage-Beach.d6058781.Car-Rental-Guide)[Osage Beach Vacation Packages](https://expedia.ca/Osage-Beach.d6058781.Destination-Travel-Guides) ![Osage Beach which includes a bay or harbour and a lake or waterhole](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257693-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Osage Beach, MO from CA $163 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Osage Beach Spa Hotels Tonight [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=6058781&startDate=2025-09-25&endDate=2025-09-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=6058781&startDate=2025-09-26&endDate=2025-09-27&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6058781&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6058781&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Osage Beach Spa Hotels ## Our top choices for Osage Beach hotels with a spa ![Couples treatment rooms, hot tub, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/4d290838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.2/10 Good (1034) "Great all inclusive place." CA $127 CA $163 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Couples treatment rooms, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/7d41cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1001) "Beautiful property....a little pricey, restaurant portions kinda small for the hefty prices...rooms where Beautiful and the beds were comfy! " CA $149 CA $212 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Couples treatment rooms, steam room, body treatments](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/c54d3975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/bfd40943.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/64c8ff64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/5bef6d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Old Kinderhook Golf Resort Camdenton 9.4/10 Exceptional (727) "Very friendly and accommodating staff! Clean and quiet :) " CA $199 CA $235 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Osage-Beach-Hotels-The-Lodge-At-Old-Kinderhook-Golf-Resort.h9785264.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/83344a11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/d8a21312.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/e7bd5e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Lake Resort Lake of the Ozarks Osage Beach 8.2/10 Very good (1015) "Fun place! " CA $184 CA $227 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=6058781&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Osage Beach Hotel Reviews ![Inn at Grand Glaize](//images.trvl-media.com/lodging/1000000/70000/60700/60685/a0b4c124_y.jpg) ### Inn at Grand Glaize 10/10 Excellent "I love the lake view you get from the room" [](https://expedia.ca/Osage-Beach-Hotels-Inn-At-Grand-Glaize.h60685.Hotel-Information) ![Quails Nest Inn and Suites](//images.trvl-media.com/lodging/10000000/9600000/9592400/9592390/1703cf6d_y.jpg) ### Quails Nest Inn and Suites 8/10 Good "nice place to stay..." [](https://expedia.ca/Osage-Beach-Hotels-Quails-Nest-Inn-And-Suites.h9592390.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "On a busy weekend staff was super helpful" [](https://expedia.ca/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Red Roof Inn Osage Beach - Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/860000/856000/855996/8cf3b5be_y.jpg) ### Red Roof Inn Osage Beach - Lake of the Ozarks 10/10 Excellent "Nice place" [](https://expedia.ca/Osage-Beach-Hotels-Red-Roof-Inn-Osage-Beach-Lake-Of-The-Ozarks.h855996.Hotel-Information) ![Days Inn by Wyndham Osage Beach Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f_y.jpg) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks 8/10 Good "Location was within walking distance of decent restaurants and easy access to the highway." [](https://expedia.ca/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) ![Baymont by Wyndham Osage Beach](//images.trvl-media.com/lodging/1000000/20000/12500/12478/07add84f_y.jpg) ### Baymont by Wyndham Osage Beach 10/10 Excellent "Check in was quick, was ready to get out of the car. " [](https://expedia.ca/Osage-Beach-Hotels-Baymont-By-Wyndham-Osage-Beach.h12478.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Osage Beach? > Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Travelers love the lakes in Osage Beach. Be sure to enjoy activities like cave exploring and fishing during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your holiday. ### What is the best spa hotel in Osage Beach? > [Margaritaville Lake Resort Lake of the Ozarks](https://www.expedia.ca/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) is a top spa hotel featuring 3 pools, 5 restaurants, a golf course, and a waterslide. Treat yourself to a facial, body scrub, or deep-tissue massage at Driftwood Spa. ### How many spa hotels will I find in Osage Beach? > Among Expedia's 1429 accommodation options in Osage Beach, there is 1 spa hotel. ### What's there to see and do in Osage Beach? > When you're in Osage Beach, enjoy exploring the sights and attractions here including Lake of the Ozarks, Osage Beach Premium Outlets, and Lake of the Ozarks State Park. If you have a little extra time during your trip, you might want to check out Jolly Mon Indoor Water Park and Miner Mike's Inc. ### What is a Osage Beach spa hotel? > Spa hotels in Osage Beach provide lodging and have an on-site spa offering services such as couples massages and body treatments. Some also offer in-room treatments. 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