Title: Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG - Latest Reviews, Deals & Photos 2025 - Expedia.ca [See all properties](http://www.expedia.ca/Hotel-Search?regionId=&adults=2&children=&sort=RECOMMENDED&useRewards=false&semdtl=&userIntent=&vip=false) # Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Hotel in Cape Girardeau with a full-service spa and free breakfast ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=resizecrop&rw=598&ra=fit) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=resizecrop&rw=297&ra=fit) - Overview - Rooms - Location - Policies Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers comfort in a rural setting with free breakfast and an indoor pool. Relax at the onsite spa and sun loungers by the pool. Dry cleaning, laundry services, and luggage storage are available, with highly praised staff. 9.4 Exceptional ## Popular amenities - - - - - Laundry - Housekeeping ## Room options ### Check availability for these dates # Tonight [Sep. 17 - Sep. 18](https://www.expedia.ca/Hotel-Search?startDate=2025-09-17&endDate=2025-09-18&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-09-17&endDate=2025-09-18&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) # Tomorrow [Sep. 18 - Sep. 19](https://www.expedia.ca/Hotel-Search?startDate=2025-09-18&endDate=2025-09-19&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-09-18&endDate=2025-09-19&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) # This weekend [Sep. 19 - Sep. 21](https://www.expedia.ca/Hotel-Search?startDate=2025-09-19&endDate=2025-09-21&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-09-19&endDate=2025-09-21&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) # Next weekend [Sep. 26 - Sep. 28](https://www.expedia.ca/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.ca/Hotel-Search?startDate=2025-09-26&endDate=2025-09-28&selected=1278542&PinnedHotelID=1278542&HadPinnedHotel=true®ionId=-1&adults=2) All rooms 1 bed 2 beds Showing 9 of 9 rooms ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/b70e9af0.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 1 King Bed 9.6 Exceptional 32 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - Sleeps 2 - 1 King Bed ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/566ace5f.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Standard Room, 1 Queen Bed 9.2 Wonderful 5 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Premium bedding - 400 sq ft - Sleeps 2 - 1 Queen Bed ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/12984f60.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 2 Queen Beds, Accessible (Mobility) 9.4 Exceptional 14 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - 400 sq ft - Sleeps 6 - 2 Queen Beds ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/566ace5f.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 2 Queen Beds 9.6 Exceptional 52 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - Sleeps 6 - 2 Queen Beds ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/566ace5f.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 1 King Bed, Accessible (Roll-In Shower) 9.6 Exceptional 5 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - Sleeps 2 - 1 King Bed ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/566ace5f.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Standard Room 8.4 Very good 5 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - 400 sq ft - Sleeps 2 - 1 King Bed ![Suite, 2 Queen Beds, Accessible (Roll-In Shower)](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/79cec4cd.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 2 Queen Beds, Accessible (Roll-In Shower) 8.0 Very good 5 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - 400 sq ft - Sleeps 6 - 2 Queen Beds ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/566ace5f.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 1 King Bed, Accessible (Mobility) 10.0 Exceptional 2 reviews ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Sofa bed - Sleeps 2 - 1 King Bed ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/566ace5f.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 1 Bedroom (Feature) 10.0 Exceptional 1 review ### Highlights Separate sitting area Air conditioning Connecting rooms available Mini-fridge Flat-screen TV Pillow menu Down duvet Premium bedding - Sleeps 2 - 1 Queen Bed ## You may also like Ad ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Hampton Inn Cape Girardeau I 55 East Cape Girardeau - Pool - Breakfast included - Pet-friendly - Parking included 9.6 Exceptional 746 reviews CA $151 CA $170 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information?chkin=2025-9-28&chkout=2025-9-29&rm1=a2®ionId=820&destination=Cape Girardeau&destType=MARKET&latLong=37.305884,-89.518148&trackingData=AAAAAQAAAAEAAAAQkvIPQqkeHaXsYHmCKu-MZxNx8rYB5W8M-fFbGvh07k0mjIuhP8WoZUMdz4VMJvdiArgs8NZc0qv_Ol72S_fOCDuTlKRipwlqbfbflWOPQ9H8qkNV4oX6VdzNO8hvABLXnrXjxg0aZRCc00KmRKNqy6bA20c4LYniIwIj4CugNgknLvVOB9BxZjWDAUxG7tQ2sXHPxzFz-3WyuaSfuYslb4PmUSvbZHQaoBDgbNYdPndetZFcMUGvx5TNJbAHIeou6_S6vQdRJlU8Ha5mHo0r8bfpvSiIfxE1GF-p-yVYoPifocDPk-Ys2aU2vBFzMzIPS7I6XLxjAB0FnMWzoZhpvm6xdv2tQE3xqchytiMLCPftPbILSg7eMZPGwCPr8dL6gqAE1yaRU8GlTqRcC1jza-ivA2cxpyKsu1Fwz2yun70xa7y2B63aappfyKiBKfI028Pq_eo-QDvGgE0Gw74NmE2QGZQTouA1ny6-Vr8Yshea2v_ojSPjPsyKGhE1iEmjv427nTcvWReeZ7NPi293Ra50LE8gTBS6QW9dpnW9IItUYnavX-gyOHX4ajhLwa5IlP1_Mujr-MBBcC5287lMT44u5wI_4Jquq-EIyYPH5wVWJRJk6GJpqFgiUdrD49MqA6s7zrXKtSbpeC1eNdh-cf59mHl6oqc6dvKMZeqpLYtM-1f4otUZKoQNLu7gcixzZuVCKmuduoGcT-lmfAaXeURGIpKSOnt9oWTBqLP6O2tHnf7gE5jc4dZiAOijkqmgckZ2sQUSzA5bwK66twg8pw1OaDKvY6FfIXh1uu8mdUYgqEZOkk1vZonVWOG_wpawQzvPD46O471i-ptDrTW-xjo_HsAgyR1cwybVmH8JMLEN9UgxEJLyOUkbJf4RSk2V_hpTSlwpn0KmEYOBK9Ms9voJN0HGjbMwqKZp7gMtUbW_S2fQAmAasZ0LvMbfLME0B5YnDu6FiCp6ulySqP1HL7xC8JZQhUkeIb_NRW-N7-qbo7PMrtW7E4GhzS-s8L6qy-kl_HXgm74DVsisqpDajbMpVj7hrevZLFK38cMNlau6B6-qrozy9AJDnVEZwDVkodMjgDa-sPi2P2jvQoN4r5-tdAzkIEm2gsI10aW1mUUf4v8ufP17Myfpp9kVeaMGKeTVoEJ_m25mAwBdPMZWFanqXNqyQNibv6GEjFaYIKJYBx7-TqRBVXf3vlvrWq9459HB9gTF_bPikX3EqqynFhym8Pg01EAkVuvR0o0S49m3K0kvtPT8UzRCh-M6roQTURMpxUebPscdmp9B6_B16UyMUa4_7Yo07ImTf17QQluI2WZog3mvxdBegeL_B5kcxZcoGrJ7tZEMWANPdtX9Rg==&rank=1&testVersionOverride=Buttercup,39483.0.0,50028.0.0,50813.0.0,51642.169494.0,49460.0.0,51690.201908.0,50988.158353.0,53583.187851.1,55903.206710.1,59537.221246.1&slots=&position=1&beaconIssued=&searchId=c8e2fb92-156c-4b26-9107-8d9226a489f5&top_cur=CAD) Ad ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau - Pool - Hot tub - Breakfast included - Pet-friendly 9.6 Exceptional 1,011 reviews CA $124 CA $139 total includes taxes & fees Sep 21 - Sep 22 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information?chkin=2025-9-21&chkout=2025-9-22&rm1=a2®ionId=820&destination=Cape Girardeau&destType=MARKET&latLong=37.305884,-89.518148&trackingData=AAAAAQAAAAEAAAAQhDij4kLPN62UHoxfBomANHcQSIv3cPcpfScnVsQG4JYTsS0tLp3vNXxZzJK5T2t-jnsyHiv9wNWM8ZnnEl9PyDtmAGo3SRE1ltM_VqLp2GYWnMH933XAz9CZeUiU6ogLlrckOt1oCtmg1iK5fpCp01EfjUWZeWu2OW8oepBvm0R-RrtjgctdNsCJejGa87RkDXgIA1allGAQC0QF3m-E6iOK7ZMqmJ6lvC0qCYl82OHceDIyzbvbT6G4Hwz3PsXjHebMmqsmXRbY78c9-OnL8LH-AwRJeuHJyraaZrciQ9qBuRmoYb1NZZiZmpaECQm7yUNe_mbva7UQYPzGottSkmYwlr--WGVd-TuTV2Pg3ctTe0akQeLSBbSxOHWrx4ARWQ3Tm8cp5lrrsMi2kXEoL-Ef7OC0ZwsES3kNo8WaTRb4XdaHCWRwwELH_yh2MH5FAeOnQocDGDen-ikqPV-XlVU7YJGB2Z1cnQh1eSNKHFB_fWIPg_BV_xsT7LuWAqzi1yoC5PTnblM8SNEl_eHPHIC0TrfidHJsTN-B6lcyLbNDdVfDnm0SrGVeiBgGpKQsHaE0xUkHoWYLDMIWQ6Vj32eMgkwLo3GLbDCmrNEVyBIWaHTPxPHOr-g4RczftPvyAbEaR3L1hB5dQ9iiqN2X7NyfX2BuYZP8hOaFiRnw1LY7p6yeXuS6gDqPcObduF624zY_5boY2PesGFwaJ6aHHJ8cqJX0k7nL4KRpHLYlN1ECw3JG-8jdodGHimgM_MX8o4GkmIUOBaRvgk9nF5mL6ij6whJ6ijx0h2LIIK-RdWm26qB_00upaWu4kdnHDQA-yGFmQzkBiWQOPKfhjH3N931t5bcV1_JttnJmznJtc899OZqhsa8-tmQtJnhnw87HXULj4YTUVHthLwOxdbpxZ1NWwKmgJ0NREJJVCF4NVfhrYiXVk7IRw8svkq2XNl3ISE8XTdUCcDJpi-dWBYkaXo_C1J1EWL_1LRs8eOB09nD3vlVSG0Cw5QdkedHZ31b5fSn_eY72FKRrK5UgMtT2cFnjFFK9qq7tYvavaw8jhqCtLL1zBxX3viLRq5GI3atRZQ29zyWmxYK8HJKmAjahMG997HEQ-lKeImbpkATiJE9u3lYk2Kt6nTkUNXLhG1v1Q8rXQN0JnKSqzLNE5spLB0sAqbgnfb58pZELtya_zErIqvDv92rTDt9WOXXyDryontjpu4r4vSuFcml2E9xP8Sk-iQOA4DSvymvYaXMohlnzY7paMbT1l3uQ66l0cM1_PeFdzUypr6yMY00zVVcdO-9u3QrRk07acpCZWLApqrSvEKtR54br36hm9M9aMyK_1lMBPebHGJI9A4woh-CQ3g==&rank=2&testVersionOverride=Buttercup,39483.0.0,50028.0.0,50813.0.0,51642.169494.0,49460.0.0,51690.201908.0,50988.158353.0,53583.187851.1,55903.206710.1,59537.221246.1&slots=&position=2&beaconIssued=&searchId=c8e2fb92-156c-4b26-9107-8d9226a489f5&top_cur=CAD) Ad ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Tru By Hilton Cape Girardeau Cape Girardeau - Pool - Breakfast included - Pet-friendly - Parking included 9.6 Exceptional 58 reviews CA $139 CA $158 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information?chkin=2025-9-25&chkout=2025-9-26&rm1=a2®ionId=820&destination=Cape Girardeau&destType=MARKET&latLong=37.305884,-89.518148&trackingData=AAAAAQAAAAEAAAAQmJWgw6d2tbLFf6LCvA3YWepAi7TqBW_u3T_K0EXPp6Hc2719uNBkrNOAXwAaUnuF7XjwZgAIbx6BG4Ze9Ecz01gD7_bQBO5jFcDNFpKXqo6BTBBaPw-UCbnTLIJBkIq1ddYNiZqQ34UB3d03Qn2qj7H5ZiNKgiTmXza0A054eDtK9pJgZxBqUYbH1ymb-k2BwGztFmsmMMOP6T7ROw5YGFg2jnLKmxj2smvdBRvAHqgmB6R5_ki1e9iEC1ia0bNppShKqpMfX7TExYORtCV-Kr-aoD47yu_pX1hg5hQVdoRl-P3F4n9oLQaKa2pB2cWFgIA61mJlOn8soNgZv5Sjbnp936EC3QZkZ6iRaKEwlo28ENzgkVlTU-biaokpk6JV28fzJJ_yXocSNQNd7lJgV3Utgkc60msuzZadEGxMcj4y7o3HpZzFFGH1UM-Ij9fG7dhfZk_o1wH9C9xksSivtMwHJZK1zaRtoonwS9q0b-xeCIOBKDyegAOqr1Rppd3qPta89BCW5PyBNQsjEswjGaUCPmklilTjN3MOFEZUnIEriyG83MUeAyPmH7Mb0b0QTjcz433KIAbY2Fg7M2EoOMeZnn2FNbEO1FFm0gzBJ5ueAXvKUgP5ePK8XgFoYf4gjB8w7T5wN24TMGzkRa5fBxYGOzbqTsdnWA2lIYKM8yVHGDKeZKj5p_PuqRImJuXzuB3J1AFZKnVoxuwz8o00xrhPLFrod8sNrbJQsvH8NxQ0G5YI9ftEI5WG99C4Fcpz07tu85wRrPv4IJbLREll6M24ocyoc_PbhtmGmWtVWb3xuOEcTSPihZmjLRApjOPRzTrR7_CpDjQWdqYbFgkAwnYjGdnGKsTmh7Ow8U74Zc8KdryAAN_l5mWKv1ZOk19JtAaEkpPisaQlndZwlwerQQG_xBf7orXIJtJpuJN3yaEV7VXqCLCwc4i96RWPFcsLPds0q3i2B_SE_nXe7AllS77LxGkslwN_E0-cixeuStYIiONgjcO_IYoPuHfe1PZ-WrRqYZBv_Cgb28xQ9jTYhgpH8wPn41O1eUpACZrIcsZdXBIULxEMh8JI4-XO1Gvj8hjLZpLI6r_BjgqQIyBnEnsd1blyXbTGWhlRmyS-9jKypNhgZoaBQVxzy0PaC1xIrzMil4svc4UICalbBqSvj4y7hMH3BOPTL3tC1p9cPID-CvfKDy0oQO0QuiKTbhNMyTN2sf10AQ3AwMdXG4olPyoL89nZ7bP2K-fxCZgk7EuPKjA9EbQD6k2AoUOZNEsFkYPpTpjXooCL5eCOUu6RfngZrM12vb0PXsGaA80O0a6Bdcy1Jfuv-4sJRlmyB2bYxx2INUT227oIKCmMm9evMg==&rank=3&testVersionOverride=Buttercup,39483.0.0,50028.0.0,50813.0.0,51642.169494.0,49460.0.0,51690.201908.0,50988.158353.0,53583.187851.1,55903.206710.1,59537.221246.1&slots=&position=3&beaconIssued=&searchId=c8e2fb92-156c-4b26-9107-8d9226a489f5&top_cur=CAD) Ad ![Lobby sitting area](https://a.travel-assets.com/media/meso_cm/PAPI/Images/lodging/106000000/105090000/105081400/105081384/b1c975d7_b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### The Riverview Cape Girardeau - Parking included - Free WiFi - Restaurant - Air conditioning 9.4 Exceptional 417 reviews CA $145 CA $163 total includes taxes & fees Sep 18 - Sep 19 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information?chkin=2025-9-18&chkout=2025-9-19&rm1=a2®ionId=820&destination=Cape Girardeau&destType=MARKET&latLong=37.305884,-89.518148&trackingData=AAAAAQAAAAEAAAAQIcS4-K7fA1MZcN9IiBidNDmdHV2jlDoR1tYhE5Laik4fJm_0FFIcACTFlkRQ7T8WqzzOySTQMZxNXelV96ZEhggnnDjd2XUr2h-Y4HwMOSYoGHXKyD_NJov1otpotS5mqwt6yarTO9-mnR6ZU33K2KQgLx2G8tdxVB6s-b8KG34_8vDF9vIN0BvXZHp0kI8DrvoirLbU6mRJVA-4SG-z4GAU4ZYd-fs7IODsCPYwvrmGuBrqODT6-VRFMOgXli9vv1UtA7_Ba-4lHYzgpuwvBEvoEqdIK3dZwehhnoMczM-z57X7YfUERH2dtkOn4uA05WqnT7cOjOHwy6yjME1RPUOb8ZACZGnx7bbBVo7J9Mv8jcGn61qXInIGdG6c1VV3oCHUT-dF4nm7w6crePGegGMfJSNEKjLtziQcSXaorDWINQMIfRx_Ts2ZPV7HI4tM8i-MgD3_qisks5dvT5QsFuK6ftPrsoy1-feJs4OsM1K3i6AqU1o_m4vFhsfynXd91Maco2VpouTjDo7EMhz9HSXn7nb1SkO5RGYaqsGSA4T_EKvj6tqEbLaUX3lwyKh-U4UuQS4sa_tdAD6-dVTBq5Yox7l4WEvbYWgTpCYPpFoKnoOXTUyJruy-MiaXVE16F6oE92K7JVFajYqis7qZfmDzS0VR0RRDxJKAzOncx5BnLyk8HPybM6NQASpc8E85joI9ZdtyVzp7kBN-2qfuD_S25GuvFwB1x_EiAXtvNZnLcA5XvU3hRchyXBXvYZeNSQYVvTYGuHveh3b81ksh3Z5wAK6bw72TPa4imZ_wbDmTgs2a8_nJ5lkHvRrS1Sz-hauqfLdahQJsvbPgUAaW07Zt0ZoSaTzhX-_Z0YMBhQoXuH5qK3OWLz29u5DgaflElxeiLqc8_73YJs4tc9KtoNpbU1vhJE_bVVor4MneKg_DAKQKLx-MXWY52vRRY1cSed7zvan3-o7eSgJyWUSzuiq5BiQPhejd1JXNjioHxCIdZJgM5586H9uyLS2ME_QoC_z-9DAzG9MPk5OtG_4T8Ha0Fuppem0btv8nUKgy0HMdU_KMxlikWAqXlFVPnv-WsDg0b7RmZh9RtWcwrrYk5lw0QAsbJ5UyMgiLDRhpfgiT2_HmOCWO_pCFmmBrXpfk642y-fiMEDtb_cOiW5MwI5N66NXLK39noZMFqlqIXGlY1W37Jxo4GiK5unqWg_BQeLZH7Ee29E1To8l-0FJFqHcPvhWe_3_jFJT_FO_dlguwj2iD8ZnHdHZHJg-lmNazNC_QlZJVUbD600D5c7V5e-dEnrteFkD7MPlENuQk06obCEmtPAmOXyKlUU-ic_FMulLSkjw4iFY3WV3_ncrKtg==&rank=4&testVersionOverride=Buttercup,39483.0.0,50028.0.0,50813.0.0,51642.169494.0,49460.0.0,51690.201908.0,50988.158353.0,53583.187851.1,55903.206710.1,59537.221246.1&slots=&position=4&beaconIssued=&searchId=c8e2fb92-156c-4b26-9107-8d9226a489f5&top_cur=CAD) ![Mod logo](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Sign in to view eligible discounts and perks. More rewards for more adventures! [Sign in](https://www.expedia.ca/login?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)[Sign up, it's free](https://www.expedia.ca/signup?enable_registration=true&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ## About the area Located in Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is in a rural area and near the airport. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. [Visit our Cape Girardeau travel guide](https://www.expedia.ca/Cape-Girardeau.dx820) ![Map](https://maps.googleapis.com/maps/api/staticmap?&size=660x330&map_id=3b266eb50d2997c6&zoom=13&markers=icon:https%3A%2F%2Fa.travel-assets.com%2Ftravel-assets-manager%2Feg-maps%2Fproperty.png%7C37.30112%2C-89.57648&channel=expedia-HotelInformation&maptype=roadmap&scale=1&key=AIzaSyCYjQus5kCufOpSj932jFoR_AJiL9yiwOw&signature=Nseq1sE6IKwLCqmhXwuRErGo2cM=) 3253 William Street, Cape Girardeau, MO, 63701 ### What's nearby - Saint Francis Medical Center - 6 min walk - 0.6 km - Southeast Missouri State University - 6 min drive - 6.0 km - Riverfront Bridge Park - 7 min drive - 6.3 km - Show Me Center - 7 min drive - 7.0 km - Isle Casino Cape Girardeau - 8 min drive - 6.9 km ### Getting around - Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive ### Restaurants - ‪Chick-fil-A - ‬7 min walk - ‪McDonald's - ‬10 min walk - ‪Rhodes - ‬20 min walk - ‪Chili's Grill & Bar - ‬4 min walk - ‪White Castle - ‬10 min walk ## About this property ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Hotel near Shawnee National Forest You can look forward to free breakfast, dry cleaning/laundry services, and a gym at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. Take some time to relax at the onsite spa. In addition to a business center, guests can connect to free in-room WiFi. You'll also enjoy perks such as: - Swimming pool along with sun loungers - Free self parking - An indoor pool, a 24-hour front desk, and a banquet hall - Free newspapers, smoke-free premises, and a vending machine - Guest reviews speak highly of the breakfast and helpful staff Room features All 102 rooms feature comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the clean rooms at the property. More amenities include: - Pillowtop mattresses and down comforters - Bathrooms with free toiletries and hair dryers - 52-inch flat-screen TVs with premium channels - Separate sitting areas, mini fridges, and microwaves ## Property amenities ### Internet - Available in all rooms: Free WiFi and wired internet - Available in some public areas: Free WiFi and wired internet ### Parking and transportation - Free self parking on site - Wheelchair-accessible parking available ### Food and drink - Free breakfast available ### Things to do - Full-service spa - Gym - Indoor pool ### Family friendly - In-room microwave - Indoor pool - Laundry facilities - Mini-fridge ### Conveniences - 24-hour front desk - Free newspapers in lobby - Laundry facilities - Luggage storage - Safe at front desk - Vending machine ### Guest services - Dry cleaning/laundry service - Housekeeping (daily) - Porter/bellhop ### Business services - 118 square feet of conference space - Business center - Meeting room ### Outdoors - Pool loungers ### Accessibility - If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking. - Assistive listening devices - Braille/raised signage - Visual fire alarm - Well-lit path to entrance - Wheelchair accessible (may have limitations) - Wheelchair-accessible parking - Wheelchair-accessible path of travel - Wheelchair-accessible path to elevator ### More - 1 building - 4 floors - Banquet hall - Smoking not allowed ## Room amenities ### Bedroom - Down comforter - Pillow menu - Pillowtop mattress - Premium bedding ### Bathroom - Free toiletries - Hair dryer - Private bathroom - Shampoo - Soap - Toilet paper - Towels provided ### Entertainment - 52-inch flat-screen TV with premium cable channels ### Food and drink - Coffee/tea maker - Microwave - Mini-fridge ### More - Air conditioning (climate-controlled) - Connecting rooms available - Desk - Free local calls - Iron/ironing board - Laptop workspace - Phone - Safe - Separate sitting area ## Policies ### Check-in Check-in start time: 3:00 PM; Check-in end time: anytime Contactless check-in available Minimum check-in age: 21 ### Check-out Check-out before 11 AM Contactless check-out available ### Special check-in instructions Front desk staff will greet guests on arrival at the property ### Access methods Staffed front desk ### Pets Pets not allowed ### Children and extra beds Children are welcome Cribs (infant beds) are not available ### Property payment types ## Important information ### You need to know Extra-person charges may apply and vary depending on property policy Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed This property accepts credit cards; cash is not accepted Cashless transactions are available Safety features at this property include a smoke detector This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG) ### We should mention Pool access available from 8 AM to 11 PM The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly) ### Property is also known as Holiday Inn Express Cape Girardeau I-55 Holiday Inn Express Hotel Cape Girardeau I-55 Holiday Inn Hotel I-55 Holiday Inn Express Hotel Suites Cape Girardeau I 55 Inn Express Cape Girarau I55 Holiday Inn Express Hotel Suites Cape Girardeau I 55 Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG ## Frequently asked questions ### Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool? > Yes, this property has an indoor pool. Pool access is from 8 AM–11 PM. ### How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG? > As of Sept 17, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Oct 5, 2025 start from CA $130.54, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. [Choose your dates](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information?rfrr=HOT.HIS.question.link.click) for more accurate prices. ### Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly? > No, pets are not allowed at this property. ### How much is parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG? > Self parking is free at this property. ### What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG? > Check-in start time: 3:00 PM; Check-in end time: anytime. ### What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG? > Check-out is at 11 AM. ### Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located? > Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 mi (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Cape Splash Family Aquatic Center is 3 mi (4.9 km) away. ## Have a question? Beta Get instant answers with AI powered search of property information and reviews. 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