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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with a fitness center and a 24-hour front desk

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
Breakfast area
Indoor pool
Lobby
1 bedroom, desk, free WiFi, bed sheets
Located off I-55, Comfort Inn & Suites Sikeston I-55 offers a welcoming retreat with an indoor pool and laundry facilities. Stay connected with in-room WiFi, get fit at the gym or conduct business in the center.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pool
  • Pet-friendly
  • Gym
  • Laundry
  • Parking included
  • Free WiFi

Room options

Available filters for rooms
Showing 5 of 5 rooms

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Highlights

Air conditioning
Refrigerator
Separate bedroom
Sofa bed
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Standard Room, 2 Queen Beds, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)

Highlights

Air conditioning
Refrigerator
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed, Accessible, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)

Highlights

Air conditioning
Refrigerator
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

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Exterior

Hampton Inn Sikeston

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8.8 out of 10, Excellent, 374 reviews
The price is CA $148
CA $167 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Sikeston
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About the area

Sikeston is home to Comfort Inn & Suites Sikeston I-55. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights.
Visit our Sikeston travel guideOpens in a new window
Map
109 Matthews Ln, Sikeston, MO, 63801

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.4 km
  • Central Park - 5 min drive - 5.5 km
  • Sikeston Depot Museum - 6 min drive - 5.5 km
  • Southeast Missouri State University - 41 min drive - 60.5 km
  • Isle Casino Cape Girardeau - 42 min drive - 61.2 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Cafe - ‬17 min walk
  • ‪McDonald's - ‬3 min walk
  • ‪Dairy Queen - ‬6 min drive
  • ‪Sonic Drive-In - ‬4 min drive
  • ‪Burger King - ‬4 min drive

About this property

Comfort Inn & Suites Sikeston I-55

Property highlights
Take advantage of laundry facilities, a gym, and a business center at Comfort Inn & Suites Sikeston I-55. Stay connected with free in-room WiFi.
Other perks include:
  • An indoor pool
  • Free self parking
  • Laundry services, an elevator, and a front-desk safe
  • A 24-hour front desk
  • Guest reviews give top marks for the helpful staff
Room features
All 64 rooms feature comforts such as air conditioning, in addition to amenities like free WiFi.
Other amenities include:
  • Bathrooms with tubs or showers
  • Cable channels, coffee/tea makers, and desks

Languages

English, Hindi

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: anytime
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 20 per pet, per night
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 20 lbs per pet)
Specific rooms only; pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of Aug 23, 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on Aug 24, 2025 start from CA $123.9, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Comfort Inn & Suites Sikeston I-55 pet-friendly?

Yes, Comfort Inn & Suites Sikeston I-55 allows cats and dogs (limit 2 total) with a maximum weight of up to 20 lbs per pet. There's a fee of USD 20 per pet, per night. Service animals are exempt from fees.

How much is parking at Comfort Inn & Suites Sikeston I-55?

Self parking is free at this property.

What time is check-in at Comfort Inn & Suites Sikeston I-55?

Check-in start time: 2:00 PM; Check-in end time: anytime.

What time is check-out at Comfort Inn & Suites Sikeston I-55?

Check-out is at 11:00 AM.

Where is Comfort Inn & Suites Sikeston I-55 located?

Situated in Sikeston, this hotel is 0.4 mi (0.6 km) from City of Miner Convention Center and within 6 mi (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.

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Comfort Inn & Suites Sikeston I-55 Reviews

Reviews

8.4

Very good

Rating 10 - Excellent. 125 out of 271 reviews
Rating 8 - Good. 91 out of 271 reviews
Rating 6 - Okay. 28 out of 271 reviews
Rating 4 - Poor. 18 out of 271 reviews
Rating 2 - Terrible. 9 out of 271 reviews

8.4/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.2/10

Property conditions & facilities

8.2/10

Eco-friendliness

Reviews

10/10 Excellent

Peggy

Liked: Cleanliness, staff & service, property conditions & facilities
The facility was very nice.
Stayed 2 nights in May 2025

8/10 Good

John

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good stay

It was decent…slept well The room was clean
Stayed 1 night in May 2025

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were in town for a pit-stop to sleep and the staff was very nice. Comfy beds and nice location
Stayed 1 night in Mar 2025

8/10 Good

Denise

hotel was fine clean and convient
Stayed 1 night in Feb 2025

10/10 Excellent

Corinthian

Liked: Cleanliness, amenities, property conditions & facilities
It was cool
Stayed 3 nights in May 2025

10/10 Excellent

Sasha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were happy with our stay
Stayed 1 night in Oct 2024

10/10 Excellent

Sharon

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice
Stayed 1 night in Apr 2025

6/10 Okay

Juanita

Liked: Cleanliness, amenities, property conditions & facilities
The check in guy threw my id at me and was rude
Stayed 3 nights in Jun 2025

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Thank you

Great stay, quiet, friendly and just what we expected!
Stayed 1 night in Feb 2025

10/10 Excellent

Timothy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean & friendly service. Easy access from the highway. Bed is comfortable. Breakfast area looks very nice. A good selection of food choices. Would recommend this property. The ice machine wasn’t working on our floor, but could get ice near the lobby, so not a huge issue.
Stayed 1 night in May 2025

10/10 Excellent

Roger

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice spacious rooms. Beds were very comfortable. Quiet place.
Stayed 1 night in Jan 2025

10/10 Excellent

John

Liked: Cleanliness, staff & service, property conditions & facilities
Great for overnights, staff friendly and attentive
Stayed 1 night in Apr 2024

8/10 Good

Dylan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Right off the main drag, huge complimentary breakfast area
Stayed 1 night in May 2024

10/10 Excellent

Tammi

Liked: Cleanliness, staff & service, property conditions & facilities
Very clean, nice staff and good breakfast
Stayed 1 night in Aug 2023

8/10 Good

Sheila a

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quiet

Clean enough though older. Main thing for me was peace and quiet so I could sleep during the day ( working nights while in town). That was great!
Stayed 2 nights in Mar 2025

10/10 Excellent

Drew

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Pit Stop

Check in was easy with friendly staff. Hotel had everything you would need, plus walking distance to dining.
Stayed 1 night in Sep 2024

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room carpet could use changing, but otherwise clean, quiet, feiendly staff, and a great morning breakfast.
Stayed 1 night in Sep 2024

10/10 Excellent

Diane

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice helpful young man checked us in. And help with our TV connection!
Stayed 1 night in Feb 2025

10/10 Excellent

Brenda

Liked: Cleanliness, property conditions & facilities, room comfort

Darrel was awesome!

Stay was good. TV wouldn’t work, Darrel came up and fixed it right away. Very nice young man.
Stayed 1 night in Mar 2025

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very enjoyable
Stayed 1 night in Oct 2024

8/10 Good

Sherry

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quick trip

Just stayed 1 night before st louis. Perfect for what we needed.I would stay again
Stayed 1 night in Oct 2024

10/10 Excellent

Marsha

Liked: Property conditions & facilities
Very clean! Bed and pillows comfortable. Pool and hot tub was nice. They had plenty of pool towels. Breakfast was okay. They had the normal breakfast but the eggs and sausage was fake. The waffles never disappoint. McDonald’s right next store if you want. Very impressed with this place. Would definitely recommend.
Stayed 1 night in Mar 2025

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Nice room for the weekend.

Great room and staff was Awesome!!
Stayed 1 night in Oct 2023

6/10 Okay

Mary Jane

Disliked: Property conditions & facilities
In need of maintenance
Stayed 1 night in Mar 2025

10/10 Excellent

Jacqueline

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

A great place to stay!

Always a friendly and helpful staff. Great breakfast in the mornings.
Stayed 1 night in Jul 2022