Sikeston

Travel Guide

Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri
Pre-teen girl walking through corn maze during fall
Columns and Dogwood Trees.  Columns from an old church surrounded by colorful dog wood trees in full bloom
Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is CA $152 per night from Jun 1 to Jun 2
CA $152
CA $175 total
Jun 1 - Jun 2
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,000 reviews)
Very nice and clean place with courteous staff.

Reviewed on May 13, 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is CA $145 per night from Jun 6 to Jun 7
CA $145
CA $164 total
Jun 6 - Jun 7
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (559 reviews)
Everything was good

Reviewed on May 10, 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is CA $124 per night from Jun 9 to Jun 10
CA $124
CA $141 total
Jun 9 - Jun 10
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,010 reviews)
Great place to stop

Reviewed on May 14, 2026

Best Western Plus Sikeston I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
New cabin in the woods with private hot tub

New cabin in the woods with private hot tub

Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions StarView Vineyards and King Neptune Memorial are ...
10/10 Exceptional! (147 reviews)
This was a nice cabin. My husband and I stayed here for a little unplugging getaway for our 9th anniversary. There was more wildlife than many other places we have been, we really enjoyed the numerous barred owls surrounding us. The cabin was clean and had everything we needed. My only suggestion ...

Reviewed on Apr 21, 2026

New cabin in the woods with private hot tub
Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!

Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!

Makanda IL
Book a stay at this golf cabin in Makanda. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Stone Creek Golf Club and Resort and Makanda ...
10/10 Exceptional! (77 reviews)
This home is just what we needed and had everything. It was a last-minute trip for us and the house count have been more perfect! The hot tub and grill were a bonus. We will definitely be back!

Reviewed on May 7, 2026

Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!
On the Shawnee Wine Trail

On the Shawnee Wine Trail

Carbondale IL
Stay at this cabin in Carbondale. Enjoy patios, cable/satellite TV service, and an in-room coffeemaker. Popular attractions Cave Hollow Trailhead and Von Jakob ...
10/10 Exceptional! (245 reviews)
Very cozy and secluded. Loved our stay here !

Reviewed on Apr 26, 2026

On the Shawnee Wine Trail
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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