Sikeston

Travel Guide

A tree with sunlight filtering through its leaves, creating a warm glow.
A person walking through a cornfield.
A building with three tall chimneys, surrounded by blooming trees with pink and white flowers.
A sign for Lambert's, a place of worship.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is CA $158 per night from Jul 15 to Jul 16
CA $158
CA $181 total
Jul 15 - Jul 16
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,000 reviews)
"Very clean"

Reviewed on Jul 1, 2026

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is CA $99 per night from Jul 6 to Jul 7
CA $99
CA $113 total
Jul 6 - Jul 7
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
"The air conditioning was good! But not very clean room. Hair everywhere. Strange fluids on bed and couch. Very spacious. You get what you pay for."

Reviewed on Jun 29, 2026

Days Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is CA $120 per night from Jul 26 to Jul 27
CA $120
CA $137 total
Jul 26 - Jul 27
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very good! (1,006 reviews)
"The room was clean. It is a little run down but not too bad at all. Be aware that you have to get a new key everyday. They didn't harass us over needing extra towels the first night but they ran out of towels the second night which is weird."

Reviewed on Jun 29, 2026

Best Western Plus Sikeston I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
New cabin in the woods with private hot tub

New cabin in the woods with private hot tub

Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions StarView Vineyards and King Neptune Memorial are ...
10/10 Exceptional! (156 reviews)
"This was a beautiful secluded cabin. I enjoyed the privacy and the beautiful drive"

Reviewed on Jun 16, 2026

New cabin in the woods with private hot tub
Brand new cabin in the woods with hot tub  1/2 mile from Starview Winery

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and in-room fireplaces. Popular attractions StarView Vineyards and King Neptune Memorial are ...
10/10 Exceptional! (169 reviews)
"Nice quiet place to stay, very close to the star view winery. 20 minutes from the Giant City lodge and Bald Knob Cross"

Reviewed on Jun 7, 2026

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Notting Hill Cottage

Notting Hill Cottage

Alto Pass IL
Stay at this vacation home in Alto Pass. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions Peachbarn Winery and Von Jakob Winery ...
9.6/10 Exceptional! (334 reviews)
"The host was great at communicating with us. The hot tub and deck was so nice! Very quiet and peaceful location! We would stay again!"

Reviewed on Jun 13, 2026

Notting Hill Cottage
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions