Sikeston Vacation Packages
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Your Sikeston Vacation
There's tons to like about Sikeston, from its rich history to its rural countryside. When you're ready to say hi to this captivating city, our Sikeston vacation packages will be perfect for you. Fill your spare time with visits to Sikeston Depot Museum, The Book Bug and Central Park, some of the top attractions you just have to see during your trip to Sikeston. That dream Sikeston vacation is clicks away. Browse hotels, flights and more on Expedia for a getaway that's tailored to suit your travel style.
Top Sikeston Vacation Deals
Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Price was CA $1,545, price is now CA $858 per person
CA $858
per person
Aug 5 - Aug 11
found 11 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to St. Louis (STL)
9.2/10 Wonderful! (1,639 reviews)
We thoroughly enjoyed our stay! We did miss getting our room cleaned on the second day and they never came back on the third. The only thing that could have improved the stay was that. The area around was so cute and we had a safe and great vacation!
Reviewed on May 16, 2026
The Knight Center at Washington University
Price was CA $1,357, price is now CA $1,005 per person
CA $1,005
per person
Aug 5 - Aug 11
found 11 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to St. Louis (STL)
9.4/10 Exceptional! (541 reviews)
Great location and perfect for event at Washington University
Reviewed on May 14, 2026
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Price was CA $1,270, price is now CA $954 per person
CA $954
per person
Aug 5 - Aug 11
found 11 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to St. Louis (STL)
8.6/10 Excellent! (1,001 reviews)
The hotel was nice staff was excellent
The room I had could use an upgrade it was a bit tiered.
Would stay again
Paul
Reviewed on May 14, 2026
Sikeston Hotel Deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $152 per night from May 31 to Jun 1
CA $152
CA $175 total
May 31 - Jun 1
includes taxes & fees
9.6/10 Exceptional! (1,001 reviews)
Very nice and clean place with courteous staff.
Reviewed on May 13, 2026
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $140 per night from Jun 14 to Jun 15
CA $140
CA $158 total
Jun 14 - Jun 15
includes taxes & fees
9/10 Wonderful! (560 reviews)
Everything was good
Reviewed on May 10, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Jun 2 to Jun 3
CA $124
CA $141 total
Jun 2 - Jun 3
includes taxes & fees
8.4/10 Very Good! (1,010 reviews)
Great place to stop
Reviewed on May 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
