Title: Sikeston Depot Museum in Sikeston - Tours and Activities | Expedia.ca [Sikeston Depot Museum Hotels](https://expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Depot Museum Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston-Depot-Museum.d6305602.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) # Sikeston Depot Museum Tours and Activities ## Visit Sikeston Depot Museum Activities [Sikeston travel guide](https://expedia.ca/Sikeston.dx6058766) --- --- ## Plan a trip to see Sikeston Depot Museum Price found within the past 48 hours. Click for updated prices. ![Hotel Indigo St Louis - Central West End by IHG](https://images.trvl-media.com/lodging/1000000/30000/22100/22068/bd89b9ce_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Indigo St Louis - Central West End by IHG Central West End CA $881 per person Apr 24 - Apr 28 found 17 hours ago Roundtrip non-stop flight included Calgary (YYC) to St. Louis (STL) 8.2/10 Very Good! (1,000 reviews) Just a really cool place. One of the cleanest hotels I've stayed in i St Louis. Everyone was really friendly. Reviewed on Feb 6, 2026 ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Wildwood Hotel CA $1,197 per person Apr 24 - Apr 28 found 17 hours ago Roundtrip non-stop flight included Calgary (YYC) to St. Louis (STL) 9.2/10 Wonderful! (1,600 reviews) Clean room and easy parking. Reviewed on Feb 2, 2026 ![Hotel Saint Louis, Autograph Collection](https://images.trvl-media.com/lodging/28000000/27480000/27478600/27478599/8a12cc18_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Saint Louis, Autograph Collection Downtown St. Louis CA $1,349 per person Apr 24 - Apr 28 found 17 hours ago Roundtrip non-stop flight included Calgary (YYC) to St. Louis (STL) 8.8/10 Excellent! (458 reviews) Property and room was really nice. I will be staying here in the future Reviewed on Nov 25, 2025 ### Popular places to visit ![View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park](https://images.trvl-media.com/place/553248621532655774/ae18e765-2c28-4c35-b4b0-74f1aaedcb22.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Riverfront Bridge Park 5/5(1 review) Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.ca/Riverfront-Bridge-Park-Cape-Girardeau.d553248621532655774.Vacation-Attraction) #### Central Park Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.ca/Central-Park-Sikeston.d6305608.Vacation-Attraction) #### City of Miner Convention Center Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants. [](https://expedia.ca/City-Of-Miner-Convention-Center-Sikeston.d818566100963352576.Vacation-Attraction) #### Front Street Studio & Art Gallery You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.ca/Front-Street-Studio-Art-Gallery-Blodgett.d553248621532655753.Vacation-Attraction) #### Stoddard County Civil War Memorial Cemetery Step back in time and learn more about local history with a stop at Stoddard County Civil War Memorial Cemetery in Dexter. While in this family-friendly area, you can enjoy the restaurants. [](https://expedia.ca/Stoddard-County-Civil-War-Memorial-Cemetery-Dexter.d553248621532655747.Vacation-Attraction) #### Hunter-Dawson State Historic Site You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your travels to New Madrid. Amble around the area's parks or experience its museums. [](https://expedia.ca/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Vacation-Attraction) --- ## Best Lodging Options Near Sikeston Depot Museum ## Check availability on hotels close to Sikeston Depot Museum [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-11&endDate=2026-02-12)[Feb 11 - Feb 12](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-11&endDate=2026-02-12) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-12&endDate=2026-02-13)[Feb 12 - Feb 13](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=2026-02-12&endDate=2026-02-13) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[Feb 13 - Feb 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[Feb 20 - Feb 22](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6305602&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott Sikeston 1239 Commerce Drive Sikeston MO [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Holiday Inn Express & Suites Sikeston Southwest by IHG](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites Sikeston Southwest by IHG 115 Hospitality Dr Sikeston MO [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Modern and Cozy Apartment with large windows and sunlight.](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Modern and Cozy Apartment with large windows and sunlight. 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