Title: Cheap Flights to Sikeston , MO from CA $230 - Expedia.ca ![The best restaurant I have EVER been to! Hands down!!!](https://images.trvl-media.com/place/553248634983441802/03fb167a-d590-4293-9dd9-648c99605c85.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Coleman ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights to Sikeston , MO from CA $230 [View CA $230 flight on Tue, Oct 28, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:YVR,to:STL,departure:28/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:229.63&airProductToken=AQo3CjUI1YIBEgQyNDcwGLiNASDyXCjXyvsCMI7O-wI4TkAAWAFqCEVDT0JBU0lDcghHTksyQTJCThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAE) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Hotels in Sikeston](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ## Popular airlines to Sikeston - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) - ![Air Canada](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AC.svg) Air Canada [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Sikeston, Missouri, United States of America,departure:08/10/2025TANYT&leg2=from:Sikeston, Missouri, United States of America,to:CMH,departure:15/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AC"}}]) - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 30% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## How much is the cheapest flight to Sikeston? Prices were available within the past 7 days and start at CA $230 for one-way flights and CA $392 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Jan 27 - Tue, Feb 3 YVR Vancouver STL St. Louis CA $392 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YVR,to:STL,departure:27/01/2026TANYT&leg2=from:STL,to:YVR,departure:03/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:391.57&airProductToken=AQppCjMIwYIBEgQxMDk5GLiNASCjsQEomsiDAzCUyoMDOEJAAFgBagVCQVNJQ3IIT1ZBQ1VTQlYKMgjBggESBDIyNjkYo7EBIPJcKOnKgwMw1suDAzhCQAFYAWoFQkFTSUNyCE9WQUNVU0JWCpwBCjEIwYIBEgQzNzQxGPJcIK4cKNCVhAMwqJaEAzhCQABYAWoFQkFTSUNyCE9WQUlWU0JYCjIIwYIBEgQxOTM4GK4cIKOxASirmIQDMNCZhAM4QkABWAFqBUJBU0lDcghPOEFDWk5CWAozCMGCARIEMTQzNBijsQEguI0BKNybhAMw9J2EAzhCQAFYAWoFQkFTSUNyCE84QUNaTkJYEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, Oct 28 - Tue, Nov 4 YVR Vancouver STL St. Louis CA $406 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YVR,to:STL,departure:28/10/2025TANYT&leg2=from:STL,to:YVR,departure:04/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:405.34&airProductToken=AQo3CjUI1YIBEgQyNDcwGLiNASDyXCjXyvsCMI7O-wI4TkAAWAFqCEVDT0JBU0lDcghHTksyQTJCTgptCjQI1YIBEgQxMzk2GPJcIINpKKSX_AIwupj8AjhOQABYAWoIRUNPQkFTSUNyCEdOSzJBMkJOCjUI1YIBEgQyNDMyGINpILiNASiJmfwCMMaa_AI4TkABWAFqCEVDT0JBU0lDcghHTksyQTJCThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAE) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Tue, Jan 13 - Sat, Jan 17 YVR Vancouver STL St. Louis CA $413 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YVR,to:STL,departure:13/01/2026TANYT&leg2=from:STL,to:YVR,departure:17/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:412.93&airProductToken=AQpgCi8IwaYBEgQyMzA0GLiNASCSASioqoIDMOuqggM4WEAAWAFqAlNWcghHSDJPWEpCTgotCMGmARIDNjE4GJIBIPJcKKCrggMwiK2CAzhYQAFYAWoCU1ZyCEdIMk9YSkJOCmAKLQjBpgESAzMxNBjyXCCSASjH2oIDMNHcggM4WEAAWAFqAlNWcghHSDJPWEpCTgovCMGmARIEMjA0MRiSASC4jQEo692CAzCn3oIDOFhAAVgBagJTVnIIR0gyT1hKQk4SCggBEAEYASoCQVMYASIECAEQASgCKAMoBDAB) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Tue, Jan 27 - Tue, Feb 3 YVR Vancouver STL St. Louis CA $421 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YVR,to:STL,departure:27/01/2026TANYT&leg2=from:STL,to:YVR,departure:03/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:420.95&airProductToken=AQpvCjYIxJgBEgQzNzEwGLiNASDyEiiby4MDMKzMgwM4RUAAWAFqCU1BSU5CQVNJQ3IIVkFWU0gzQkMKNQjEmAESBDI2NjYY8hIg8lwo8syDAzCezoMDOEVAAVgBaglNQUlOQkFTSUNyCFZBVlNIM0JDEgoIARABGAEqAkRMGAEiBAgBEAEoAigDKAQwAQ) ![Air Canada](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AC.gif) Tue, Dec 16 - Tue, Jan 6 YOW Ottawa STL St. Louis CA $429 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YOW,to:STL,departure:16/12/2025TANYT&leg2=from:STL,to:YOW,departure:06/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:428.20&airProductToken=AQpoCjIIwYYBEgM0NDUY2LMBIJjOASi37_8CMIjw_wI4R0AAWAFqBUJBU0lDcghHTkEyQTBCQQoyCMGGARIEODk2ORiYzgEg8lwo1PH_AjDp8v8COEdAAVgBagVCQVNJQ3IIR05BMkEwQkEKaAoyCMGGARIEODk3MBjyXCCYzgEord-BAzCm4IEDOEdAAFgBagVCQVNJQ3IIR05BMkEwQkEKMgjBhgESAzQ3MBiYzgEg2LMBKNThgQMwmOKBAzhHQAFYAWoFQkFTSUNyCEdOQTJBMEJBEgoIARABGAEqAkFDGAEiBAgBEAEoAigDKAQwDQ) ## Find the cheapest month to fly from Columbus (CMH) to St. Louis (STL) ### August is typically the cheapest month to fly From CA $199 - CA $693 per traveller. Expedia.ca gives you the best tools to secure great deals on flights to Sikeston. Use our easy and convenient booking engine to browse nonstop flights and convenient departure points every day of the year. Search airfares from the top airlines to book your perfect flight to Sikeston. Whatever your travel needs, you can always rely on Expedia.ca to help you find cheap flights to Sikeston. Using our booking engine is simple - just type in your points of travel and preferred dates and Expedia.ca does the rest! If your travel times are flexible, you can find even better bargains by adjusting your flight dates. Browse connecting flights to increase your chances of finding even lower fares. Thanks to Expedia's Best Price Guarantee, you can book your Sikeston flights with full confidence knowing that you've found the best deal online. Expedia.ca makes the booking process easy and stress-free by offering support along the entire way. Our friendly staff is available 24 hours a day to provide assistance and help you book your ticket. Call us toll-free at 1-888-397-3342 to answer any questions that you may have about your trip to Sikeston. Looking to save even more? Get additional savings by bundling your Sikeston flight with a hotel and/or car rental to create a bargain travel package. Early birds can discover terrific savings by booking in advance while last minute travelers can enjoy great last minute deals. With Expedia.ca, there's no shortage of options to save even more on your Sikeston trip! Flights to Sikeston information | Destination airport | Lambert-St. Louis Intl. | | --- | --- | | Destination airport IATA code | STL | | Destination city name | St. Louis | | Roundtrip price | CA $392 | ## Need more than a Flight to Sikeston? Heading to Sikeston? Explore Sikeston with Expedia's Travel Guides to find the best hotels, vacation packages, car rental deals and more! [Sikeston Hotels](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide) ## Trending flights to Sikeston Prices were available within the past 7 days and start at CA $230 for one-way flights and CA $392 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Jan 27 - Tue, Feb 3 YVR Vancouver STL St. Louis CA $392 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YVR,to:STL,departure:27/01/2026TANYT&leg2=from:STL,to:YVR,departure:03/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:391.57&airProductToken=AQppCjMIwYIBEgQxMDk5GLiNASCjsQEomsiDAzCUyoMDOEJAAFgBagVCQVNJQ3IIT1ZBQ1VTQlYKMgjBggESBDIyNjkYo7EBIPJcKOnKgwMw1suDAzhCQAFYAWoFQkFTSUNyCE9WQUNVU0JWCpwBCjEIwYIBEgQzNzQxGPJcIK4cKNCVhAMwqJaEAzhCQABYAWoFQkFTSUNyCE9WQUlWU0JYCjIIwYIBEgQxOTM4GK4cIKOxASirmIQDMNCZhAM4QkABWAFqBUJBU0lDcghPOEFDWk5CWAozCMGCARIEMTQzNBijsQEguI0BKNybhAMw9J2EAzhCQAFYAWoFQkFTSUNyCE84QUNaTkJYEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ## Explore a world of travel with Expedia - Lodging - Flights - 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