Book The Best Hotels in Poplar Bluff, MO for 2026 from CA $77 - Fully Refundable Options

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Our top choices for Poplar Bluff hotels

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

1. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Paul

CA $141

CA $160 total

includes taxes & fees

Sep 6 - Sep 7

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

2. Hampton Inn Poplar Bluff

Poplar Bluff

Sheila

CA $130

CA $145 total

includes taxes & fees

Sep 20 - Sep 21

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

A motel with a prominent '66' sign, large windows, and a flat roof.

3. Motel 6 Poplar Bluff, MO

Poplar Bluff

Mark

CA $109

CA $123 total

includes taxes & fees

Sep 4 - Sep 5

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A corner market with a refrigerated display case and a pantry area.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

4. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Arsenia

CA $141

CA $159 total

includes taxes & fees

Sep 13 - Sep 14

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

An indoor swimming pool with clear water, marked depth lines, and lounge chairs along the side.

A hotel lobby with a reception desk, seating area, and a television screen.

A bathroom with a shower, a sink, and a mirror.

5. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

Stephanie

CA $122

CA $138 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A two-story motel with a covered parking area and a bench outside.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

6. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

Diana

CA $97

CA $109 total

includes taxes & fees

Sep 21 - Sep 22

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

7. Comfort Inn Poplar Bluff North

Poplar Bluff

Muhammad

CA $122

CA $138 total

includes taxes & fees

Sep 20 - Sep 21

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

8. Hampton Inn By Hilton Dexter

Dexter

Lauren

CA $135

CA $152 total

includes taxes & fees

Sep 20 - Sep 21

A wooden gazebo, a clock, outdoor seating, and a small garden area.

A lodge with a prominent sign, a covered entrance, and a balcony.

A bar with wooden ceiling, bar stools, and a sign reading "Bullwinkles".

A kitchen with wooden cabinets, a dishwasher, a sink, and a coffee maker. There are framed pictures on the wall and a fish hanging above the sink.

9. Bullwinkles Rustic Lodge

Poplar Bluff

Brenden

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

10. Dexter Inn

Dexter

Edward

CA $86

CA $97 total

includes taxes & fees

Sep 8 - Sep 9

A diner with booth seating, a checkered floor, and a counter with a cash register.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

11. Travelodge by Wyndham Dexter

Dexter

Steven

CA $127

CA $142 total

includes taxes & fees

Sep 17 - Sep 18

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A bathroom with a bathtub, toilet, and a shower curtain.

A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

12. OYO Hickory House Inn

Dexter

Tammy

CA $63

CA $77 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

13. Econo Lodge Dexter

Dexter

Elizabeth

CA $71

CA $80 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a bed, a chair, a desk, a lamp, and a window with curtains.

A hotel room with a bed, a chair, a desk, and a lamp.

A wooden dresser with a mirror above it, a black refrigerator, and a small table with a cloth.

14. Parkview Motel

Corning

sunday

A hotel room with two beds, a wooden chair, a desk, and a mirror.

A building with a sign reading "Airport Inn" and a large "N" on the facade.

A hallway with vending machines, including a Pepsi and a Coca-Cola machine, and a door at the end.

A reception desk with a pet fee sign, no smoking sign, and a pet bell sign.

15. OYO Malden Airport Inn

Malden

James

CA $60

CA $69 total

includes taxes & fees

Sep 16 - Sep 17

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Stay near popular Poplar Bluff attractions

Black River Coliseum

8.2/10 (30 reviews)

Catch an event at Black River Coliseum during your trip to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.

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North Main Street Historic District

You can find out about the history of Poplar Bluff with a trip to North Main Street Historic District. While in this family-friendly area, you can enjoy the restaurants.

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Mo-Ark Regional Railroad Museum

6.8/10 (13 reviews)

You can study the exhibits at Mo-Ark Regional Railroad Museum, a museum with a storied past, during your travels to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.

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Margaret Harwell Art Museum

5.8/10 (8 reviews)

You can study the exhibits at Margaret Harwell Art Museum, a museum with a storied past, during your travels to Poplar Bluff. Stroll along the riverfront or experience the entertainment venues in this family-friendly area.

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Ozark Ridge Golf Course

7.4/10 (3 reviews)

Enjoy a round of golf in Poplar Bluff at Ozark Ridge Golf Course. Take in the entertainment venues and waterfalls in the area.

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Learn more about Poplar Bluff

Outdoor enthusiasts flock to Lake Wappapello for boating and fishing, while the historic downtown reveals Poplar Bluff's riverboat-era charm. Visit the Black River Heritage Centre first to understand the region's history before exploring the scenic Ozark foothills on nearby hiking trails.

See all hotels in Poplar Bluff

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.

Top Poplar Bluff Hotel Reviews

Holiday Inn Poplar Bluff by IHG

8/10 Good

"Everything was good, the only issue I had. Was served the wrong breakfast . Then charged $18.00 for the difference. But the restaurant was busy. So I paid and never said anything. Including the ham I got that I don’t eat."

Super 8 by Wyndham Poplar Bluff Missouri

10/10 Excellent

"For the price it was a very good room"

Hampton Inn Poplar Bluff

10/10 Excellent

"Great spot close to the college. Clean, quiet and staff were great"

Motel 6 Poplar Bluff, MO

10/10 Excellent

"The room was clean and the bed was comfortable. It was also quiet making it easy to get some sleep before getting back on the road."

Eden’s Rest – Cozy 2BR Cabin in the Woods

10/10 Excellent

"Very friendly, easy check in and out. Beautiful place with everything you needed. Quiet. Peaceful, and country hide away."

Home Sweet Home, Spacious Sunroom & Fun Deck!

10/10 Excellent

"We really enjoyed our stay in this home. The kitchen was so well equipped with everything that you could ever hope for. My granddaughter has stayed in several Vrbo and has never seen a kitchen so well equipped. We really enjoyed the sun room and deck. The property is central located for easy access to the surrounding town. I would definitely rent this home again."

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

8/10 Good

"The house was clean and had everything we needed."

40-Acre Poplar Bluff Nature Lovers Paradise!

8/10 Good

"Beautiful location!! Had issues with the key pad - other than that all was great!"

Cozy 2-bedroom house in welcoming Poplar Bluff

10/10 Excellent

"This property suited our needs just fine for an overnight stay on the way to Louisville."