Title: Book The Best Hotels in Sikeston, MO for 2026 from CA $80 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Sikeston](https://expedia.ca/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Sikeston Pool [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=PETS) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=CABIN) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&amenities=HOT_TUB) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&travelerType=family_friendly) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=APARTMENT) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-04-14&d1=2026-04-14&endDate=2026-04-16&d2=2026-04-16&lodging=COTTAGE) ## Check prices for these dates Tonight [Mar 31 - Apr 1](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 1 - Apr 2](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Sikeston hotels ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1,000 reviews) "Great room, staff and breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth CA $142 CA $160 total includes taxes & fees Apr 8 - Apr 9 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/b5f01af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1,003 reviews) "Great food and pool. Clean and cozy. We will be back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leora CA $111 CA $118 total includes taxes & fees Apr 6 - Apr 7 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature)](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,000 reviews) "This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber CA $146 CA $165 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.4/10 Exceptional (67 reviews) "Nice quiet hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $153 CA $173 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,002 reviews) "Clean room, friendly staff, great breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jessica CA $139 CA $157 total includes taxes & fees Apr 29 - Apr 30 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (524 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) grant CA $146 CA $165 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (736 reviews) "Very clean and staff was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nastassia CA $124 CA $134 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jackpot Suite | Living area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (538 reviews) "Room was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derrick CA $164 CA $185 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (116 reviews) "Hotel was very clean, quiet and has a great location! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustin CA $124 CA $142 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,002 reviews) "Very nice folks who manage the hotel!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jane CA $102 CA $116 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/dba6fd48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible (Tub)](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/86c003aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/fe0d924e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,000 reviews) "My wife and I stay was absolutely lovely. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chad CA $100 CA $113 total includes taxes & fees Apr 8 - Apr 9 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.6/10 Exceptional (1,007 reviews) "Very nice for overnight stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $131 CA $150 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (453 reviews) "Clean rooms, friendly staff and convenient location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $130 CA $147 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (168 reviews) "Nearby Mexican restaurant, clean room, pleasant staff, good breakfast choices " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry CA $129 CA $145 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/c7d69739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (499 reviews) "Beautiful property! Quick easy walk to downtown. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelley CA $193 CA $219 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/e6e29f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/b20a49e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/81fbb6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (801 reviews) "We enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wanda CA $165 CA $187 total includes taxes & fees Apr 3 - Apr 4 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/594efec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (758 reviews) "Very nice place, very nice stay! They were out of cream cheese for the bagels at breakfast though.:-)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $86 CA $98 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/a42cb957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/08c2ace2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/15abbdc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d0a59214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverstone Hotel Charleston-Sikeston [](https://www.expedia.ca/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) Charleston 6.8/10 (410 reviews) "Clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $111 CA $123 total includes taxes & fees May 2 - May 3 [](https://www.expedia.ca/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.4/10 Exceptional (16 reviews) "This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $177 CA $200 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/3d86dbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,003 reviews) "Business friendly, clean room staff very friendly, accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice CA $95 CA $108 total includes taxes & fees Apr 7 - Apr 8 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16®ionId=6058766&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels.d6058766.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels.d6058766.Travel-Guide-Hotels) ## Stay near popular Sikeston attractions ### Sikeston Depot Museum 3.8/5 (33 reviews) You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6305602) ### Central Park 3.8/5 (36 reviews) Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6305608) ### City of Miner Convention Center Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this family-friendly area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=818566100963352576) ## Sikeston and related destinations - Sikeston - Florence - Los Banos - Olive Branch - Lima Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August. [See all hotels in Sikeston](https://www.expedia.ca/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16&adults=2®ionId=6058766) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Sikeston Hotel Reviews ## Recent Reviews in Sikeston ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95_y.jpg) ### Pear Tree Inn Cape Girardeau West 6/10 Okay "Overall the room was nice but the website say that they offer happy hour and they don’t offer anything like that they just offer popcorn ..breakfast is good overall " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Parking was available for my handicap son ,breakfast was great,very clean room and friendly staff " [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg) ### Hampton Inn Sikeston 8/10 Good "Yes, breakfast was fresh. Room temperature was comfortable. Overall stay was good. Would stay there again" [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Really nice rooms" [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Holiday Inn Express & Suites Sikeston Southwest by IHG](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a_y.jpg) ### Holiday Inn Express & Suites Sikeston Southwest by IHG 2/10 Terrible "The only thing good about our stay was the breasfast everything else was not. Room was not cleaned properly with leftover food in 2 corners of the rook and bobby pins on ottoman. The bath tube took forever to drain same with sink. White stuff on headboard. The room was so nasty. " [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 6/10 Okay "Not much of a breakfast. The smell entering the hotel was terrible. My husband has COPD and could barely breath. Room was nice" [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "Hotel is in a convenient central area. Was clean and staff was friendly." [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Best Western Plus Sikeston I-55](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston I-55 4/10 Poor "The bed and chair was hard. Will not go back" [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Our first visit to a Drury Inn — what an amazing place. Not only was there an excellent breakfast with many choices, but there was also a light dinner served. This was all included for a very reasonable price. Our room was very clean and comfortable. We will definitely be looking for more Drury Inns as we travel. " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ## More cheap stays in Sikeston ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 100 Matthews Lane Sikeston MO CA $86 CA $98 total Apr 9 - Apr 10 includes taxes & fees 8.4/10 Very Good! (758 reviews) [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO CA $95 CA $108 total Apr 8 - Apr 9 includes taxes & fees 7.2/10 Good! (1,003 reviews) [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO CA $100 CA $113 total Apr 8 - Apr 9 includes taxes & fees 9/10 Wonderful! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO CA $146 CA $165 total Apr 12 - Apr 13 includes taxes & fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO CA $146 CA $165 total Apr 9 - Apr 10 includes taxes & fees 9/10 Wonderful! (524 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St Perryville MO CA $153 CA $175 total Apr 12 - Apr 13 includes taxes & fees 9.2/10 Wonderful! (572 reviews) [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ## Hotels in Sikeston with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 3 properties [](https://expedia.ca/4Star-Sikeston-Hotels.s40-0-d6058766.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 15 properties [](https://expedia.ca/3Star-Sikeston-Hotels.s30-0-d6058766.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 67 properties [](https://expedia.ca/2Star-Sikeston-Hotels.s20-0-d6058766.Travel-Guide-Filter-Hotels) ## Find out more about Sikeston ### Top reasons to visit Sikeston - **Outdoor Adventures:** Sikeston is perfect for outdoor enthusiasts, offering recreational areas for picnics and nature walks. - **Cultural Exploration:** Immerse yourself in local culture by visiting art museums and historic houses. - **Family-Friendly Activities:** Enjoy various activities suitable for families, ensuring a fun experience for all ages. - **Charming Downtown:** Explore the historic downtown filled with friendly locals and unique shops. - **Convenient Accommodations:** Choose from budget-friendly hotels with essential amenities for a comfortable stay. ### Find great hotels in Sikeston Explore a variety of hotel accommodations in Sikeston, Missouri, where you'll find budget-friendly options ranging from 2 to 3 stars. Whether you're travelling with family, on business, or bringing your furry friend along, Sikeston offers hotels tailored to your needs. Enjoy a comfortable stay with essential amenities and discover the best lodging options to make your visit memorable. - **[Days Inn and Suites by Wyndham Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)** Located in the heart of Sikeston, Days Inn and Suites offers a comfortable retreat for both leisure and business travellers. With a distinct Pet-Friendly theme, this hotel welcomes furry companions while providing essential business amenities like multiple meeting rooms. Guests can enjoy conveniences such as free Wi-Fi and a relaxing environment, making it ideal for those who need to mix work with pleasure. The pet policy includes restrictions but allows dogs and cats, ensuring every member of the family can join the trip. - **[Pear Tree Inn Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)** Pear Tree Inn is a family-oriented hotel that combines comfort with modern amenities. Perfect for those travelling with children, this property features complimentary cribs and a welcoming atmosphere for pets. Business travellers will appreciate the dedicated business centre, while families can enjoy spacious rooms designed for relaxation. With a focus on both family and pet-friendly experiences, this hotel ensures that everyone feels at home, making it an excellent choice for a memorable stay in Sikeston. - **[Best Western Plus Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)** Best Western Plus Sikeston stands out for its strong emphasis on pet-friendly accommodations. This hotel allows pets and offers a welcoming environment for those travelling with their furry friends. Guests can take advantage of the comfortable rooms and convenient amenities, including a complimentary breakfast. With a commitment to providing a pleasant stay, this hotel is an excellent option for pet owners seeking both comfort and practicality in Sikeston. ### Where to stay in Sikeston Sikeston, Missouri, offers a delightful blend of outdoor adventures and charming scenery, perfect for romantic getaways or family-friendly vacations. Explore the historic downtown, where friendly locals create a warm atmosphere. Just a short drive away, discover nearby Mississippi County and its inviting neighbourhoods, ideal for budget-friendly excursions. Whether you're seeking a vibrant city vibe or tranquil retreats, Sikeston and its surroundings promise memorable experiences for every traveller. - **[Miner:](https://www.expedia.ca/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels)** Nestled in the Sikeston region, Miner is a charming village that offers a delightful blend of outdoor activities and family-friendly experiences. While visitor numbers tend to peak in January and during the summer months, the village remains a welcoming destination year-round. Outdoor enthusiasts will enjoy the scenic beauty and recreational areas nearby, including a national state park and a tranquil lake. With convenient access to shopping centres and local stores, Miner is an ideal spot for families seeking a memorable getaway. - **[Morehouse:](https://www.expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels)** Situated a mere 9.7km from Sikeston, Morehouse is a quaint city that promises a relaxed travel experience. Although it doesn't have distinct seasonal fluctuations in visitor numbers, the summer months—particularly from June to August—see a notable influx of tourists. Morehouse is perfect for those looking to explore a close-knit community with a blend of local charm and accessibility to nearby attractions, making it a great addition to your travel itinerary. - **[Bertrand:](https://www.expedia.ca/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels)** Located 12.9km from Sikeston, Bertrand is a vibrant city known for its outdoor adventures and family experiences. With visitor numbers peaking in January, April, and August, it offers a welcoming atmosphere throughout the year. Nature lovers can explore nearby landmarks such as a visitor centre, serene lakes, and nature reserves, providing plenty of opportunities for hiking and wildlife observation. Bertrand is an excellent choice for visitors looking to immerse themselves in nature while enjoying the warmth of a small-town community. ### Things to do in Sikeston Sikeston, Missouri, offers a delightful blend of outdoor activities and scenic beauty perfect for a romantic getaway. Tourists can enjoy the recreational area for picnics, visit the local casino for some entertainment, and explore the arena facility for various events. Whether you're looking to relax in nature or engage in lively activities, Sikeston has something to offer everyone. **Shopping** The Book Bug is a charming store in Sikeston, perfect for unique gifts and souvenirs. If you're up for a drive, consider visiting the nearby Richmond Mall for a wider selection of shops, including clothing and home decor stores. **Recreation** Experience the scenic [Boot Heel Golf Club](https://www.expedia.ca/Boot-Heel-Golf-Club-Hotels.0-l6305606-0.Travel-Guide-Filter-Hotels) for a round of golf amidst beautiful landscapes, perfect for outdoor enthusiasts. For ultimate relaxation, visit [eDen Spa & Salon](https://www.expedia.ca/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels), where you can indulge in rejuvenating body treatments, ideal for unwinding after a day of exploration. **Nightlife** A night in Sikeston offers a blend of excitement and relaxation. Visit the [Isle Casino Cape Girardeau](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels), located 48.3km away, for a vibrant experience filled with gaming and city vibes. Enjoy the romantic atmosphere as you try your luck and indulge in delicious dining options. ### Booking tips and Expedia advantages for Sikeston To save money during your trip to Sikeston, consider visiting between November and January when hotel prices are lower, especially on Tuesdays. Avoid Saturdays for the best rates. Opt for economical transportation methods like walking or biking, as the city is quite compact. When booking, use Expedia’s search tool to compare hotel deals and consider bundling your accommodations with flights for additional savings. Finally, take advantage of free activities in the area to enhance your experience without stretching your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and the type of hotel you’re looking for. To uncover the best prices and deals, be sure to sort the price filter from lowest to highest. - **Consider bundling your trip:** You can potentially save money by combining your Sikeston hotel reservation with your flights and activities through an Expedia package. ### Find the best attractions in Sikeston Sikeston, Missouri, is perfect for outdoor enthusiasts and those seeking romantic getaways, featuring attractions such as event venues, art museums, and historic houses. Visitors can immerse themselves in local culture while enjoying family-friendly activities. For a well-rounded experience, explore nearby attractions and consider staying at hotels close to the Sikeston Depot Museum for added convenience. - **[Sikeston Depot Museum:](https://www.expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)** Immerse yourself in the rich culture of Sikeston at this art museum, which showcases local history and art. The museum's unique exhibits and charming atmosphere provide a fascinating glimpse into the region’s heritage. - **[Central Park:](https://www.expedia.ca/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels)** A perfect spot for families, Central Park offers expansive green spaces and recreational facilities. Enjoy outdoor activities like picnicking or leisurely strolls, all while soaking in the vibrant city vibes of Sikeston. - **[Front Street Studio & Art Gallery:](https://www.expedia.ca/Front-Street-Studio-Art-Gallery-Hotels.0-l553248621532655753-0.Travel-Guide-Filter-Hotels)** Located 14.5km away, this art gallery features an array of local artworks, creating a cultural haven. The gallery's inviting ambience encourages creativity and appreciation for the arts. ### Best time to go to Sikeston Visitor numbers in Sikeston is generally unchanged in popularity throughout the year. The best time to visit Sikeston is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 36.0°F (2.2°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | February | 39.2°F (4.0°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | March | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average | | April | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 77.2°F (25.1°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | July | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 77.5°F (25.3°C) | Light Rain | Mostly Sunny | Slightly High | Average | | September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Average | Average | | October | 60.8°F (16.0°C) | Light Rain | Mostly Sunny | Average | Average | | November | 48.6°F (9.2°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 41.2°F (5.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Sikeston To visit Sikeston, Missouri, you can fly into several nearby airports. Paducah, KY (PAH-Barkley Regional) is located 75.6km away, with hotel options like [The Respite Bed and Breakfast](https://www.expedia.ca/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information), [Harrah's Metropolis Hotel & Casino](https://www.expedia.ca/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information), and [The 1857](https://www.expedia.ca/Paducah-Hotels-The-1857.h15338500.Hotel-Information). Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 38.6km from Sikeston, offering accommodations such as Drury Plaza Hotel, Drury Inn & Suites, and Courtyard by Marriott. Another option is Cairo, IL (CIR-Cairo Regional), also 38.6km away, where you can find Quality Inn Cairo, Super 8 by Wyndham, and [Eagle Inn Charleston](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information). Each airport provides convenient access to various lodging choices for your stay. ## Frequently asked questions ### What is the best area to stay in Sikeston? > This central area is the commercial heart of Sikeston. You'll find a good selection of hotels, restaurants, and shops concentrated along South Main Street and nearby streets. It's a practical base for exploring the town or as a stopover for those travelling through. > > > For solo travellers or couples looking for convenience, staying near the main thoroughfares provides easy access to dining options, including local favourites and well-known eateries. Many hotels in this area offer comfortable stays with good amenities, ensuring a relaxed experience after a day of travel. > > > Families will also appreciate the ease of access to restaurants and services in this central location. ### What are the best hotels in Sikeston that travellers recommend? > The 3-star Hampton Inn Sikeston, with a 9.0 rating, is highly praised for its great breakfast and nice, clean rooms. Guests also appreciate the friendly staff and the indoor pool. It is conveniently located just 1.6 km from Central Park. > > > Another excellent option is the 3-star Holiday Inn Express & Suites Sikeston Southwest by IHG, which has an 8.6 rating. Guests consistently highlight the great breakfast, good rooms, and friendly staff. This hotel also features an indoor pool and is 1.5 km from Central Park. ### What are the best family hotels in Sikeston? > The 3-star Drury Inn & Suites Sikeston, MO, with an impressive 9.4 rating, is a fantastic choice for families. Guests frequently praise the free and great breakfast, comfortable and clean rooms, and excellent and friendly staff. The location is also described as superb and convenient, and the food is fresh and fabulous. This hotel offers free cribs and sofa beds for added family comfort. > > > Another highly-rated option is the Pear Tree Inn Sikeston, boasting a 9.4 rating. Families will appreciate the comfortable and clean rooms, friendly and helpful staff, and the good, free breakfast. It also provides connecting rooms and free cribs, making it suitable for larger families. > > > The Fairfield Inn & Suites by Marriott Sikeston, with a 9.2 rating, is another great family-friendly hotel. It features a pool, sofa beds, and free buffet breakfast. Travel cribs are also available. This hotel is conveniently located just 1.9 km from Central Park. > > > With a 9.0 rating, the Hampton Inn Sikeston offers a pool, free breakfast, free WiFi, and free self-parking. Guests often praise the great and good breakfast, nice and clean rooms, and great staff. It is also close to Central Park, just 1.6 km away. > > > Finally, the 3-star TownePlace Suites by Marriott Sikeston, rated 8.8, is ideal for families seeking extended stays. It offers travel cribs, connecting rooms, sofa beds, and free self-serve breakfast. This hotel is also located 1.9 km from Central Park. Find more [child-friendly accommodations in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Family-Hotel.0-0-d6058766-tFamilyHotel.Travel-Guide-Filter-Hotels) ### What hotels in Sikeston offer free breakfast? > The 3-star Drury Inn & Suites Sikeston, MO, boasting an excellent 9.4 rating, offers both free breakfast and a free buffet breakfast. Guests consistently praise the comfortable and clean rooms, the excellent and friendly staff, and the fresh and fabulous food. Its convenient location is also a frequent highlight. > > > Another highly-rated option is the Pear Tree Inn Sikeston, with a 9.4 rating. This hotel provides free breakfast and is known for its comfortable and clean rooms and friendly, helpful staff. Guests particularly appreciate the good breakfast and great amenities. > > > The Hampton Inn Sikeston, rated 9.0, includes free breakfast and a complimentary continental breakfast. It is conveniently located just 1.6 km from Central Park. Guests frequently mention the great breakfast and nice, clean rooms. > > > The Holiday Inn Express & Suites Sikeston Southwest by IHG, with an 8.6 rating, offers both free breakfast and a complimentary continental breakfast. This hotel is also very close to Central Park, just 1.5 km away. Guests often comment on the great breakfast and friendly staff. > > > Finally, the Best Western Plus Sikeston, rated 8.4, provides a free full breakfast as well as a general free breakfast offering. Visitors often praise the great breakfast, comfortable and clean rooms, and the friendly and fantastic staff. Find more [hotels with free breakfast in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Hotels-With-Free-Breakfast.0-0-d6058766-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) ### What are the top pet-friendly hotels in Sikeston? > The 3-star Drury Inn & Suites Sikeston, MO, with an excellent 9.4 rating, is highly regarded for its pet-friendly policies. Guests frequently praise the free buffet breakfast, the comfortable and clean rooms, and the excellent and friendly staff. Its convenient location is also a plus for travellers. > > > Another excellent option is the Pear Tree Inn Sikeston, which also boasts a 9.4 rating. This hotel offers comfortable and clean rooms, and guests consistently highlight the friendly and helpful staff. A free and good breakfast is also a popular feature. See more [pet-friendly hotels in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Pet-Friendly-Hotel.0-0-d6058766-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) ### What are the best budget hotels in Sikeston? > The 3-star Drury Inn & Suites Sikeston, MO, boasts an outstanding 9.4 rating. Guests consistently praise the complimentary breakfast for being both free and delicious, the comfortable and clean rooms, and the exceptionally friendly and helpful staff. Its convenient location is also a frequent highlight. > > > Another great option is the Hampton Inn Sikeston, which has a strong 9.0 rating. This hotel offers a complimentary breakfast and free Wi-Fi, along with clean and nice rooms. It is conveniently located just 1.6 km from Central Park. > > > The Best Western Plus Sikeston, with an 8.4 rating, is also a good choice for budget travellers. Guests appreciate the excellent complimentary breakfast, the comfortable and clean rooms, and the friendly staff. View all [budget hotels in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Cheap-Hotels.0-0-d6058766-tCheapHotels.Travel-Guide-Filter-Hotels) ### What are the most romantic hotels in Sikeston for couples? > This hotel provides spacious suites, making it ideal for a romantic getaway. Guests frequently mention the clean and big rooms, the comfy beds, and the friendly staff. A complimentary breakfast is also available, with options for free grab-and-go selections, adding to the convenience for couples. Free WiFi and complimentary self-parking are also provided. See all [romantic hotels in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Romantic-Hotel.0-0-d6058766-tRomanticHotel.Travel-Guide-Filter-Hotels) ### What are the best hotels in Sikeston near Central Park? > The Hampton Inn Sikeston, with a 9.0 rating, is conveniently located just 1.6 kilometres from Central Park. Guests frequently praise the great breakfast, the nice, clean rooms, and the great staff. The hotel also offers a pool, free WiFi, and complimentary toiletries. > > > Another excellent choice is the Holiday Inn Express & Suites Sikeston Southwest by IHG, rated 8.6, and only 1.5 kilometres from Central Park. This hotel provides connecting rooms, free cribs, and a complimentary continental breakfast. Guests have highlighted the good rooms and friendly staff. ### When is the best time to go to Sikeston? > These seasons offer pleasant weather, with moderate temperatures and lower humidity, making it comfortable for exploring the area. During these times, you'll find the local landscape is particularly appealing, whether it's the fresh greenery of spring or the colourful foliage of autumn. This is ideal for those who enjoy outdoor activities or simply prefer milder conditions for their travels. > > > Families often find these periods convenient as well, as the comfortable weather is suitable for visiting local parks or participating in community events without the extreme heat of summer. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Sikeston hotel booking with Expedia? ### How much is the nightly rate at a Sikeston hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [B&B in Advance ](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Advance ](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [Advance Hotels ](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Lodges in Advance ](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - 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