Title: Book The Best Hotels in Sikeston, MO for 2025 from CA $84 - Competitive Prices - Expedia.ca

  

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Photo by Ryan Coleman

# Find hotels in Sikeston, MO from CA $84

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## Go beyond your typical stay in Sikeston

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=CABIN)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=POOL)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=PETS)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=HOT_TUB)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&travelerType=family_friendly)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&lodging=APARTMENT)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America&regionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2025-11-18&d1=2025-11-18&endDate=2025-11-20&d2=2025-11-20&amenities=WATER_PARK)

## Check prices for these dates

Tonight

[Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 278 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

Sikeston

9.4/10

Exceptional

(1002)

"Clean room, great location and friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mark

CA $132

CA $151 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

8.8/10

Excellent

(417)

"Nice property and friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nancy

CA $137

CA $155 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn and Suites by Wyndham Sikeston

Sikeston

7.2/10

Good

(1003)

"Clean and comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jim

CA $88

CA $100 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Sikeston

Sikeston

9.4/10

Exceptional

(1001)

"Everything was up to par. Enjoyed our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Greg

CA $108

CA $124 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

8.4/10

Very good

(702)

"Very quiet and comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lana

CA $79

CA $91 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Sikeston

Sikeston

8.4/10

Very good

(1016)

"Very convenient and great breakfast "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Duwaine

CA $118

CA $134 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, down comforters, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

8.6/10

Excellent

(435)

"staff was friendly nothing to crazy about this hotel "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isaac

CA $142

CA $160 total

includes taxes & fees

Dec 5 - Dec 6

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Sikeston

Sikeston

9.2/10

Wonderful

(28)

"Hotel was clean, the toilets could use some attention, but staff was friendly and the breakfast was good"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

CA $142

CA $161 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Sikeston/Miner Area

Sikeston

6.6/10

(558)

"I enjoyed our stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alex

CA $88

CA $100 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/131ce4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Yard Inn and Suite

Sikeston

6.8/10

(112)

"Property is a little old. Needs some improvements. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dean

CA $70

CA $84 total

includes taxes & fees

Nov 26 - Nov 27

[](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1010)

"Nice place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

CA $123

CA $130 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/d534aac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/235e013f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5641af73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Sikeston I-55

Sikeston

8.4/10

Very good

(274)

"It was a very nice stay. The pool was clean and enjoying!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

CA $124

CA $141 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(646)

"Stayed on our way south for vacation. It was a clean nice place to stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joel

CA $118

CA $128 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

Cape Girardeau

9.0/10

Wonderful

(1006)

"Great hotel service and stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig

CA $98

CA $111 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/917691e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Sikeston

Sikeston

8.4/10

Very good

(5)

"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Scott

CA $170

CA $193 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1000)

"Great place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

CA $132

CA $149 total

includes taxes & fees

Nov 14 - Nov 15

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

Cape Girardeau

9.4/10

Exceptional

(1007)

"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sandra

CA $126

CA $143 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1005)

"Always enjoy our stay. Staff is very friendly, especially at breakfast! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $94

CA $106 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

9.4/10

Exceptional

(1000)

"Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Penny

CA $139

CA $157 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

6.6/10

(602)

"Tracey Allen checked me in. She was great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

CA $79

CA $87 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Save an average of 15% on thousands of hotels when you're signed in

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## Check out pet-friendly hotels in Sikeston

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

8.4/10

Very good

(702)

CA $79

CA $91 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Sikeston

Sikeston

8.4/10

Very good

(1016)

CA $118

CA $134 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1010)

CA $123

CA $130 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1000)

CA $132

CA $149 total

includes taxes & fees

Nov 14 - Nov 15

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1005)

CA $94

CA $106 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

8.8/10

Excellent

(417)

CA $137

CA $155 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn and Suites by Wyndham Sikeston

Sikeston

7.2/10

Good

(1003)

CA $88

CA $100 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Sikeston

Sikeston

9.4/10

Exceptional

(1001)

CA $108

CA $124 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

6.6/10

(602)

CA $79

CA $87 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

Cape Girardeau

9.4/10

Exceptional

(1007)

CA $126

CA $143 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&regionId=6058766&adults=2&amenities=PETS&openPlayBack=true)

## Hotels with free breakfast in Sikeston you'll enjoy

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

9.4/10

Exceptional

(1000)

CA $139

CA $157 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Sikeston

Sikeston

8.4/10

Very good

(1016)

CA $118

CA $134 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

8.4/10

Very good

(702)

CA $79

CA $91 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(646)

CA $118

CA $128 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1010)

CA $123

CA $130 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Jackson-Cape Girardeau

Jackson

8.2/10

Very good

(738)

CA $125

CA $135 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1005)

CA $94

CA $106 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Sikeston

Sikeston

9.4/10

Exceptional

(1001)

CA $108

CA $124 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1000)

CA $132

CA $149 total

includes taxes & fees

Nov 14 - Nov 15

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

8.8/10

Excellent

(417)

CA $137

CA $155 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&regionId=6058766&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

## These family-friendly hotels in Sikeston may fit your trip

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Sikeston

Sikeston

9.4/10

Exceptional

(1001)

CA $108

CA $124 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Jackson-Cape Girardeau

Jackson

8.2/10

Very good

(738)

CA $125

CA $135 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(646)

CA $118

CA $128 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

Cape Girardeau

9.0/10

Wonderful

(1006)

CA $98

CA $111 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/cde4423c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/94d9e92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/074a1dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Charleston - Sikeston

Charleston

6.8/10

(406)

CA $92

CA $102 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

Sikeston

9.4/10

Exceptional

(1002)

CA $132

CA $151 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

6.6/10

(602)

CA $79

CA $87 total

includes taxes & fees

Nov 5 - Nov 6

[](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

![Studio, 1 King Bed](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn By Hilton Dexter

Dexter

CA $137

CA $154 total

includes taxes & fees

Dec 5 - Dec 6

[](https://www.expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/8fbe165c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/f3b3697d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/9a624d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dexter Inn

Dexter

7.0/10

Good

(329)

CA $87

CA $98 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1000)

CA $132

CA $149 total

includes taxes & fees

Nov 14 - Nov 15

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&regionId=6058766&adults=2&travelerType=family_friendly&openPlayBack=true)

## Sikeston and related destinations

-   Sikeston
-   Florence
-   Los Banos
-   Lima

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

[See all hotels in Sikeston](https://www.expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19&adults=2&regionId=6058766)

![The best restaurant I have EVER been to! Hands down!!!](https://images.trvl-media.com/place/553248634983441802/03fb167a-d590-4293-9dd9-648c99605c85.jpg?impolicy=fcrop&w=655&h=655&p=1&q=high)

Photo by Ryan Coleman

### Stay near popular Sikeston attractions

[](https://expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)

#### Sikeston Depot Museum

You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6305602)

[](https://expedia.ca/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels)

#### Central Park

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6305608)

## More cheap stays in Sikeston

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr, Sikeston, MO

CA $88

CA $100 total

Dec 2 - Dec 3

includes taxes & fees

7.2/10 Good! (1,002 reviews)

[](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau, MO

CA $94

CA $106 total

Nov 17 - Nov 18

includes taxes & fees

8.8/10 Excellent! (1,003 reviews)

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Sikeston

1240 Commerce Drive, Sikeston, MO

CA $137

CA $155 total

Nov 16 - Nov 17

includes taxes & fees

8.8/10 Excellent! (417 reviews)

[](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St, Perryville, MO

CA $134

CA $153 total

Nov 9 - Nov 10

includes taxes & fees

9.2/10 Wonderful! (524 reviews)

[](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information)

![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn

2011 North Kingshighway, Cape Girardeau, MO

CA $84

CA $95 total

Nov 13 - Nov 14

includes taxes & fees

7/10 Good! (662 reviews)

[](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy, Cape Girardeau, MO

CA $98

CA $111 total

Nov 12 - Nov 13

includes taxes & fees

9/10 Wonderful! (1,004 reviews)

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

## Hotels in Sikeston with star-rating

![4 Star Hotels](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_w.jpg)

4 Star Hotels

2 properties

[](https://expedia.ca/4Star-Sikeston-Hotels.s40-0-d6058766.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_w.jpg)

3 Star Hotels

15 properties

[](https://expedia.ca/3Star-Sikeston-Hotels.s30-0-d6058766.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_w.jpg)

2 Star Hotels

53 properties

[](https://expedia.ca/2Star-Sikeston-Hotels.s20-0-d6058766.Travel-Guide-Filter-Hotels)

## Find out more about Sikeston

### Top reasons to visit Sikeston

-   **Outdoor Adventures:** Sikeston is perfect for outdoor enthusiasts, offering recreational areas for picnics and nature walks.
-   **Cultural Exploration:** Immerse yourself in local culture by visiting art museums and historic houses.
-   **Family-Friendly Activities:** Enjoy various activities suitable for families, ensuring a fun experience for all ages.
-   **Charming Downtown:** Explore the historic downtown filled with friendly locals and unique shops.
-   **Convenient Accommodations:** Choose from budget-friendly hotels with essential amenities for a comfortable stay.

### Find great hotels in Sikeston

Explore a variety of hotel accommodations in Sikeston, Missouri, where you'll find budget-friendly options ranging from 2 to 3 stars. Whether you're travelling with family, on business, or bringing your furry friend along, Sikeston offers hotels tailored to your needs. Enjoy a comfortable stay with essential amenities and discover the best lodging options to make your visit memorable.

-   **[Days Inn and Suites by Wyndham Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)** Located in the heart of Sikeston, Days Inn and Suites offers a comfortable retreat for both leisure and business travellers. With a distinct Pet-Friendly theme, this hotel welcomes furry companions while providing essential business amenities like multiple meeting rooms. Guests can enjoy conveniences such as free Wi-Fi and a relaxing environment, making it ideal for those who need to mix work with pleasure. The pet policy includes restrictions but allows dogs and cats, ensuring every member of the family can join the trip.
-   **[Pear Tree Inn Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)** Pear Tree Inn is a family-oriented hotel that combines comfort with modern amenities. Perfect for those travelling with children, this property features complimentary cribs and a welcoming atmosphere for pets. Business travellers will appreciate the dedicated business centre, while families can enjoy spacious rooms designed for relaxation. With a focus on both family and pet-friendly experiences, this hotel ensures that everyone feels at home, making it an excellent choice for a memorable stay in Sikeston.
-   **[Best Western Plus Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)** Best Western Plus Sikeston stands out for its strong emphasis on pet-friendly accommodations. This hotel allows pets and offers a welcoming environment for those travelling with their furry friends. Guests can take advantage of the comfortable rooms and convenient amenities, including a complimentary breakfast. With a commitment to providing a pleasant stay, this hotel is an excellent option for pet owners seeking both comfort and practicality in Sikeston.

### Where to stay in Sikeston

Sikeston, Missouri, offers a delightful blend of outdoor adventures and charming scenery, perfect for romantic getaways or family-friendly vacations. Explore the historic downtown, where friendly locals create a warm atmosphere. Just a short drive away, discover nearby Mississippi County and its inviting neighbourhoods, ideal for budget-friendly excursions. Whether you're seeking a vibrant city vibe or tranquil retreats, Sikeston and its surroundings promise memorable experiences for every traveller.

-   **[Miner:](https://www.expedia.ca/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels)** Nestled in the Sikeston region, Miner is a charming village that offers a delightful blend of outdoor activities and family-friendly experiences. While visitor numbers tend to peak in January and during the summer months, the village remains a welcoming destination year-round. Outdoor enthusiasts will enjoy the scenic beauty and recreational areas nearby, including a national state park and a tranquil lake. With convenient access to shopping centres and local stores, Miner is an ideal spot for families seeking a memorable getaway.
-   **[Morehouse:](https://www.expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels)** Situated a mere 9.7km from Sikeston, Morehouse is a quaint city that promises a relaxed travel experience. Although it doesn't have distinct seasonal fluctuations in visitor numbers, the summer months—particularly from June to August—see a notable influx of tourists. Morehouse is perfect for those looking to explore a close-knit community with a blend of local charm and accessibility to nearby attractions, making it a great addition to your travel itinerary.
-   **[Bertrand:](https://www.expedia.ca/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels)** Located 12.9km from Sikeston, Bertrand is a vibrant city known for its outdoor adventures and family experiences. With visitor numbers peaking in January, April, and August, it offers a welcoming atmosphere throughout the year. Nature lovers can explore nearby landmarks such as a visitor centre, serene lakes, and nature reserves, providing plenty of opportunities for hiking and wildlife observation. Bertrand is an excellent choice for visitors looking to immerse themselves in nature while enjoying the warmth of a small-town community.

### Things to do in Sikeston

Sikeston, Missouri, offers a delightful blend of outdoor activities and scenic beauty perfect for a romantic getaway. Tourists can enjoy the recreational area for picnics, visit the local casino for some entertainment, and explore the arena facility for various events. Whether you're looking to relax in nature or engage in lively activities, Sikeston has something to offer everyone.

**Shopping**

The Book Bug is a charming store in Sikeston, perfect for unique gifts and souvenirs. If you're up for a drive, consider visiting the nearby Richmond Mall for a wider selection of shops, including clothing and home decor stores.

**Recreation**

Experience the scenic [Boot Heel Golf Club](https://www.expedia.ca/Boot-Heel-Golf-Club-Hotels.0-l6305606-0.Travel-Guide-Filter-Hotels) for a round of golf amidst beautiful landscapes, perfect for outdoor enthusiasts. For ultimate relaxation, visit [eDen Spa & Salon](https://www.expedia.ca/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels), where you can indulge in rejuvenating body treatments, ideal for unwinding after a day of exploration.

**Nightlife**

A night in Sikeston offers a blend of excitement and relaxation. Visit the [Isle Casino Cape Girardeau](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels), located 48.3km away, for a vibrant experience filled with gaming and city vibes. Enjoy the romantic atmosphere as you try your luck and indulge in delicious dining options.

### Booking tips and Expedia advantages for Sikeston

To save money during your trip to Sikeston, consider visiting between November and January when hotel prices are lower, especially on Tuesdays. Avoid Saturdays for the best rates. Opt for economical transportation methods like walking or biking, as the city is quite compact. When booking, use Expedia’s search tool to compare hotel deals and consider bundling your accommodations with flights for additional savings. Finally, take advantage of free activities in the area to enhance your experience without stretching your budget.

-   **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
-   **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday.
-   **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and the type of hotel you’re looking for. To uncover the best prices and deals, be sure to sort the price filter from lowest to highest.
-   **Consider bundling your trip:** You can potentially save money by combining your Sikeston hotel reservation with your flights and activities through an Expedia package.

### Find the best attractions in Sikeston

Sikeston, Missouri, is perfect for outdoor enthusiasts and those seeking romantic getaways, featuring attractions such as event venues, art museums, and historic houses. Visitors can immerse themselves in local culture while enjoying family-friendly activities. For a well-rounded experience, explore nearby attractions and consider staying at hotels close to the Sikeston Depot Museum for added convenience.

-   **[Sikeston Depot Museum:](https://www.expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)** Immerse yourself in the rich culture of Sikeston at this art museum, which showcases local history and art. The museum's unique exhibits and charming atmosphere provide a fascinating glimpse into the region’s heritage.
-   **[Central Park:](https://www.expedia.ca/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels)** A perfect spot for families, Central Park offers expansive green spaces and recreational facilities. Enjoy outdoor activities like picnicking or leisurely strolls, all while soaking in the vibrant city vibes of Sikeston.
-   **[Front Street Studio & Art Gallery:](https://www.expedia.ca/Front-Street-Studio-Art-Gallery-Hotels.0-l553248621532655753-0.Travel-Guide-Filter-Hotels)** Located 14.5km away, this art gallery features an array of local artworks, creating a cultural haven. The gallery's inviting ambience encourages creativity and appreciation for the arts.

### Best time to go to Sikeston

Visitor numbers in Sikeston is generally unchanged in popularity throughout the year. The best time to visit Sikeston is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

| **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** |
| --- | --- | --- | --- | --- | --- |
| January | 36.0°F (2.2°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low |
| February | 39.2°F (4.0°C) | Light Rain | Mostly Sunny | Slightly Low | Average |
| March | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average |
| April | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Slightly High |
| May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Average | Slightly High |
| June | 77.2°F (25.1°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High |
| July | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Slightly High | Average |
| August | 77.5°F (25.3°C) | Light Rain | Mostly Sunny | Slightly High | Average |
| September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Average | Average |
| October | 60.8°F (16.0°C) | Light Rain | Mostly Sunny | Average | Average |
| November | 48.6°F (9.2°C) | Light Rain | Mostly Sunny | Average | Slightly Low |
| December | 41.2°F (5.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low |

### The nearest major airports for your trip to Sikeston

To visit Sikeston, Missouri, you can fly into several nearby airports. Paducah, KY (PAH-Barkley Regional) is located 75.6km away, with hotel options like [The Respite Bed and Breakfast](https://www.expedia.ca/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information), [Harrah's Metropolis Hotel & Casino](https://www.expedia.ca/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information), and [The 1857](https://www.expedia.ca/Paducah-Hotels-The-1857.h15338500.Hotel-Information). Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 38.6km from Sikeston, offering accommodations such as Drury Plaza Hotel, Drury Inn & Suites, and Courtyard by Marriott. Another option is Cairo, IL (CIR-Cairo Regional), also 38.6km away, where you can find Quality Inn Cairo, Super 8 by Wyndham, and [Eagle Inn Charleston](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information). Each airport provides convenient access to various lodging choices for your stay.

## Recent reviews of Sikeston hotels

![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

5/5 Excellent

"Clean room, great location and friendly staff"

A verified traveller from Germantown stayed at Drury Inn & Suites Sikeston, MO

Posted 2 days ago

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg)

### Tru By Hilton Cape Girardeau

5/5 Excellent

"The eggs were fake and the turkey sausage was bad "

A verified traveller stayed at Tru By Hilton Cape Girardeau

Posted 2 days ago

[](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg)

### Pear Tree Inn Sikeston

5/5 Excellent

"Good breakfast options. Reasonable rate. Clean"

A verified traveller stayed at Pear Tree Inn Sikeston

Posted 2 days ago

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg)

### Drury Inn & Suites Cape Girardeau

5/5 Excellent

"Great service "

A verified traveller stayed at Drury Inn & Suites Cape Girardeau

Posted 3 days ago

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

5/5 Excellent

"Yes "

A verified traveller stayed at Days Inn and Suites by Wyndham Sikeston

Posted 3 days ago

[](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

5/5 Excellent

"Overall had a comfortable stay. Safe and convenient location. Free breakfast buffet was good, clean. Toaster was not working during our stay, but other than that, was ok. "

A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Posted 5 days ago

[](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Hampton Inn Sikeston](//images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg)

### Hampton Inn Sikeston

5/5 Excellent

"We had a great room. It was clean and the staff was friendly and helpful. The only thing that happened was the elevators went out during the night. I would definitely stay there again. "

A verified traveller stayed at Hampton Inn Sikeston

Posted 5 days ago

[](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

5/5 Excellent

"Over all everything was excellent!"

A verified traveller stayed at Drury Inn & Suites Jackson MO

Posted 5 days ago

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

5/5 Excellent

"My room was close to the entrance as requested, clean and comfortable. The parking lot was well lit with side access available. Breakfast included many choices and dining area was very clean. All the staff I encountered were very nice. I was traveling alone and felt very safe.."

A verified traveller stayed at Pear Tree Inn Cape Girardeau West

Posted 6 days ago

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

## Frequently asked questions

### How much does a spa hotel in Sikeston cost?

> Enjoy staying in a spa hotel in Sikeston, with plenty of hotels from CA $84 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.

### Is it cheaper to book a spa hotel in Sikeston with flights as part of a package deal?

> Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.

### Are there any unique spa experiences available in Sikeston?

> Yes, Sikeston offers several unique spa experiences, including the 573 Head Spa, Dawn of Life Aesthetics & Wellness Med Spa, and Aesthetic Day Spa.
> 
>   
> 
> The 573 Head Spa specialises in natural scalp and hair health, utilising ancient Japanese head spa techniques for a distinctive and exclusive treatment.
> 
>   
> 
> Dawn of Life Aesthetics & Wellness Med Spa provides a broad range of services, including facials, microneedling, laser hair removal, IV therapy, body contouring, red light therapy, and medical weight loss treatments.
> 
>   
> 
> Aesthetic Day Spa focuses on helping clients look and feel their best with services such as facials, relaxation massages, full body waxing, body treatments, and brow/lash tinting.
> 
>   
> 
> For accommodations with spa amenities, [Pear Tree Inn Sikeston](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) features an indoor and outdoor pool plus a hot tub.

### How can I save on a spa hotel in Sikeston with Expedia?

> Members always get our best prices. Find our best Sikeston spa hotel deals by joining Expedia's free travel rewards program—[One Key™](https://www.expedia.ca/welcome-one-key). As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers.

### Can I cancel my spa hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Sikeston for you.

### How can I save on a pet-friendly hotel in Sikeston with Expedia?

> There are plenty of ways to save on a pet-friendly hotel in Sikeston. Join [One Key™](https://www.expedia.ca/welcome-one-key)—Expedia's free travel rewards program—to unlock discounted Member Prices. Typically, booking in advance will help you save on your pet-friendly hotel booking.

### Do any Sikeston hotels have restrictions on pet sizes or breeds?

> First ensure you have picked a pet-friendly hotel by using the "Pet friendly" filter under the "Amenities" section in your search. If a hotel in Sikeston has restrictions on pet sizes or breeds, you will find this information clearly in their property listing on Expedia. When you're on the property listing page, simply click on "Policies" to see what pet-specific policies the hotel implements.

### Is it cheaper to book flights and a pet-friendly hotel in Sikeston as a package?

> Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.

### Can I cancel my pet-friendly hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right pet-friendly hotel in Sikeston for you.

### How much is the nightly rate at a Sikeston hotel?

> Prices for hotels in Sikeston often vary, but you can find a great deal from CA $84 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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-   [Flights to Dexter](https://www.expedia.ca/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights)
-   [Flights from East Prairie](https://www.expedia.ca/lp/flights/3000349349/flights-from-east-prairie)
-   [Flights from Commerce](https://www.expedia.ca/lp/flights/553248634983177483/flights-from-commerce)
-   [Flights from Chaffee](https://www.expedia.ca/lp/flights/553248634983269107/flights-from-chaffee)
-   [Flights from Scott City](https://www.expedia.ca/lp/flights/553248634983544376/flights-from-scott-city)
-   [Flights from Accra (ACC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/acc/cgi/accra-to-cape-girardeau)
-   [Flights from Colombo (CMB) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/cmb/cgi/colombo-to-cape-girardeau)
-   [Flights from Detroit (DTW) to Sikeston (SIK)](https://www.expedia.ca/lp/flights/dtw/sik/detroit-to-sikeston)
-   [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/jfk/cgi/new-york-to-cape-girardeau)
-   [Flights from St. Louis (STL) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/stl/cgi/st-louis-to-cape-girardeau)
-   [Flights from Edmonton (YEG) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yeg/cgi/edmonton-to-cape-girardeau)
-   [Flights from Toronto (YTO) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yto/cgi/toronto-to-cape-girardeau)
-   [Flights from Montreal (YUL) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yul/cgi/montreal-to-cape-girardeau)
-   [Flights from Vancouver (YVR) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yvr/cgi/vancouver-to-cape-girardeau)
-   [Flights from Winnipeg (YWG) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/ywg/cgi/winnipeg-to-cape-girardeau)
-   [Flights from Calgary (YYC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yyc/cgi/calgary-to-cape-girardeau)
-   [Flights from Toronto (YYZ) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yyz/cgi/toronto-to-cape-girardeau)

-   [Rental cars Cape Girardeau Municipal airport](https://www.expedia.ca/Car-Rentals-In-Cape-Girardeau-Municipal.d6026978.Car-Rental-Guide)

-   [Book Hotels in Sikeston on Expedia.com](https://www.expedia.com/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)

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