Title: Top 10 3 Star Hotels in Sikeston CA $128: Find a Three Star Hotel in Sikeston | Expedia.ca [Sikeston Travel Guide](https://expedia.ca/Sikeston.dx6058766)[Hotels in Sikeston](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Vacation Rentals in Sikeston](https://expedia.ca/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Coleman # 3 Star Hotels in Sikeston CA $128 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sikeston 3 Star Hotels Tonight [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-05&endDate=2025-11-06&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 6 - Nov 7](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-06&endDate=2025-11-07&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sikeston 3 Star Hotels ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1002) " The staff was polite and the room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margaret CA $133 CA $150 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (647) "Stayed on our way south for vacation. It was a clean nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joel CA $119 CA $128 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1002) "Clean room, great location and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $133 CA $152 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1002) "Nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $124 CA $131 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1000) "Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $127 CA $143 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (458) "Very clean and upscale hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $164 CA $185 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/917691e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston Sikeston 8.4/10 Very good (5) "I loved all of what this property had to offer " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian CA $171 CA $193 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/5f50a8a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel Marble Hill 9.6/10 Exceptional (80) "This hotel has a lot of character and was so cozy. The owners have done a wonderful job creating a lovely, super easy hotel experience. The diner and mercantile were very cool. Everything felt very clean and welcoming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melisa [](https://www.expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/06b8cd59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/327c3e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts Perryville 9.2/10 Wonderful (17) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric [](https://www.expedia.ca/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556900/98556805/fc2782f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556900/98556805/3a2f5e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556900/98556805/eccb9234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556900/98556805/2b9085ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Murphysboro Retreat w/ Deck Near Kinkaid Lake! Murphysboro 10/10 Exceptional (1) "This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didn’t bring something for it which made me sad. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ross [](https://www.expedia.ca/Murphysboro-Hotels-Murphysboro-Retreat-W-Deck-Near-Kinkaid-Lake.h98556805.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/d6ab8f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/f6b73146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/0b616d8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage, Multiple Beds, Non Smoking (West End Cottage)](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/a07ef7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Makanda Inn Makanda 10/10 Exceptional (33) "Big thank you to the team at the cabin! Great people, great service, and great food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $378 CA $431 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103970000/103967200/103967134/cb2d64d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103970000/103967200/103967134/81190003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103970000/103967200/103967134/30699625.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/104000000/103970000/103967200/103967134/2cfb45fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Anna Home Near Southern Illinois Attractions! Anna 10/10 Exceptional (1) "Good communication with the owners. Nice perks such as coffee, tea, and hygiene items." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harvey [](https://www.expedia.ca/Anna-Hotels-Cozy-Anna-Home-Near-Southern-Illinois-Attractions.h103967134.Hotel-Information) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/3a8929c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/d44ed252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/cadf7b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/a3e823f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'the Lakehouse' Lovely Wappapello Country Home! Wappapello [](https://www.expedia.ca/Wappapello-Hotels-Lovely-Wappapello-Country-Home-Near-Lake.h93537801.Hotel-Information) ![House (Multiple Bedrooms) | Front of property](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/0d97a5c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/bec5a95e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/c805c602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/036f729d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious & Secluded Shook Home w/ Private Hot Tub! Lowndes [](https://www.expedia.ca/Spacious-Secluded-Shook-Home-W-Private-Hot-Tub.h99391486.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20460000/20451700/20451643/7cea78f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20460000/20451700/20451643/731f74d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20460000/20451700/20451643/4b8f1291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, Private Bathroom (Cabin 3)](https://images.trvl-media.com/lodging/21000000/20460000/20451700/20451643/fbdbb643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oak Grove Cabins Makanda 10/10 Exceptional (5) "Awsome cabin and really private. Lots of nice touches. Great coverage for our Verizon hotspot." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/Carbondale-Hotels-Oak-Grove-Cabins.h20451643.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Sikeston-Hotels.s30-0-d6058766.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F3Star-Sikeston-Hotels.s30-0-d6058766.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Sikeston. ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO CA $128 CA $145 total Nov 10 - Nov 11 includes taxes & fees 9.2/10 Wonderful! (443 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Davie School Inn](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/3020a524_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Davie School Inn 300 Freeman St, Anna, IL [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F11%2F2025&endDate=21%2F11%2F2025&selected=33418130&PinnedHotelID=33418130&HadPinnedHotel=true®ionId=6058766) 10/10 Exceptional! (51 reviews) [](https://expedia.ca/Anna-Hotels-Davie-School-Inn.h33418130.Hotel-Information) ![Urban Lofts](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Urban Lofts 104 North Jackson Street, Perryville, MO [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F11%2F2025&endDate=21%2F11%2F2025&selected=39926011&PinnedHotelID=39926011&HadPinnedHotel=true®ionId=6058766) [](https://expedia.ca/Perryville-Hotels-Urban-Lofts.h39926011.Hotel-Information) Still don't see what you're looking for? [See all properties in Sikeston.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F11%2F2025&endDate=08%2F11%2F2025®ionId=6058766&star=30) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F11%2F2025&endDate=08%2F11%2F2025®ionId=6058766&star=30&star=30&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F11%2F2025&endDate=08%2F11%2F2025®ionId=6058766&star=30&star=30&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F11%2F2025&endDate=08%2F11%2F2025®ionId=6058766&star=30&star=30&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F11%2F2025&endDate=08%2F11%2F2025®ionId=6058766&star=30&star=30&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F11%2F2025&endDate=08%2F11%2F2025®ionId=6058766&star=30&star=30&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Sikeston and related destinations - Sikeston - Florence - Los Banos - Lima Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August. [See all hotels in Sikeston](https://www.expedia.ca/Hotel-Search?startDate=2025-11-20&endDate=2025-11-21&adults=2®ionId=6058766) ![The best restaurant I have EVER been to! Hands down!!!](https://images.trvl-media.com/place/553248634983441802/03fb167a-d590-4293-9dd9-648c99605c85.jpg?impolicy=fcrop&w=655&h=655&p=1&q=high) Photo by Ryan Coleman ## Top Sikeston Hotel Reviews ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room, great location and friendly staff" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Great service " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Overall had a comfortable stay. Safe and convenient location. Free breakfast buffet was good, clean. Toaster was not working during our stay, but other than that, was ok. " [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Over all everything was excellent!" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Beds were comfortable and good breakfast" [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Nice and quiet, beautiful and historic!" [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ## Find out more about Sikeston The top 3 Stars hotels in Sikeston, Sikeston may offer some of the best discounts and rates, but these properties are anything but average. Travelers love Sikeston 3 Stars hotels for their top quality services, just-like-home amenities, and wallet-friendly prices. You can even get access to fantastic perks like delectable restaurants, so-cool cocktail bars, and spacious fitness centres. Use the travel tools at Expedia.ca to find a cheap deal on a 3 Stars upscale hotel in Sikeston for a first-class experience, or book an inexpensive rate on one of the cheap 3 Stars hotels in Sikeston neighbourhoods near the city’s best attractions. We’ll even help you find vacation packages to go with your three star hotel in Sikeston. From last-minute work trips to long-awaited family getaways, we offer all the essentials you need to enjoy your jaunt through Sikeston. ## Frequently asked questions ### What are the best 3-star hotels in Sikeston? > Relax in budget-friendly comfort at [Drury Inn & Suites Sikeston, MO](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information). Situated about 5 kilometres east of downtown Sikeston, this 3-star hotel is highly recommended by Expedia customers. ### How much does it cost to stay in a 3-star hotel in Sikeston? > Make use of Expedia's search filters to look for a good-value 3-star hotel for your upcoming Sikeston trip. Simply set your budget with our pricing tool. You can also choose the amenities you need, favourite area and loads more. > > > > - Search for the lowest price per night right now from CA $145 ### What is the difference between a 4-star and 3-star hotel in Sikeston? > Relaxation is easy in 3-star hotels in Sikeston. In addition to comfortable surroundings, these more affordable properties include an array of welcome amenities like complimentary WiFi, coffee maker and gym facilities. A 4-star hotel offers a classier experience with enhanced features such as a wellness centre, indoor or outdoor pool and bigger rooms. 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