
Scott County Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $1,096 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Scott County Vacation
Leave all the planning to us with a Scott County vacation package. With everything organized before you go, the only thing left to do is sit back, relax and experience this destination's countless delights. Start your trip to Scott County by spending a few nights in Sikeston, one of the top cities here. Quit dreaming and get packing, because your Scott County vacation is only a few clicks away with Expedia.
Scott County Hotel Deals

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Apr 9 to Apr 10
CA $153
CA $176 total
Apr 9 - Apr 10
includes taxes & fees
9.6/10 Exceptional! (1,007 reviews)
Our first visit to a Drury Inn — what an amazing place. Not only was there an excellent breakfast with many choices, but there was also a light dinner served. This was all included for a very reasonable price. Our room was very clean and comfortable. We will definitely be looking for more Drury Inns ...
Reviewed on Mar 30, 2026

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $120 per night from Apr 5 to Apr 6
CA $120
CA $136 total
Apr 5 - Apr 6
includes taxes & fees
8.4/10 Very Good! (1,002 reviews)
The bed and chair was hard. Will not go back
Reviewed on Mar 30, 2026

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $86 per night from Apr 9 to Apr 10
CA $86
CA $98 total
Apr 9 - Apr 10
includes taxes & fees
8.4/10 Very Good! (758 reviews)
Not much of a breakfast. The smell entering the hotel was terrible. My husband has COPD and could barely breath. Room was nice
Reviewed on Mar 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







