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Cape Girardeau Vacation Rentals

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Vacation Rentals in Cape Girardeau

Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

10.0 out of 10, Exceptional, (21)
"Chip was an excellent host, always available to provide tips about restaurants and answer any questions about the property. Property was in great condition and would not hesitate to recommend."
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

Little Blue Cottage on Spanish

8.6 out of 10, Excellent, (43)
"Has everything you need. Comfy and in a great location. "
The price is CA $111
CA $139 total
includes taxes & fees
Aug 19 - Aug 20
Little Blue Cottage on Spanish

Loft Apartment Across From Semo University Houch Field House. Walk To Events

10.0 out of 10, Exceptional, (89)
"Great place to stay if you are visiting SEMO or Cape in general. The owner was nice and flexible, making our stay so much better. I travelled with my 16-month-old, and the whole house felt safe and clean. Narrow stairs can be tough for older folks. But didn't concern us much, even with a baby. The kitchen and bathroom have everything you need. Highly recommended. "
The price is CA $206
CA $252 total
includes taxes & fees
Aug 14 - Aug 15
Loft Apartment Across From Semo University Houch Field House. Walk To Events

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (139)
"The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area."
The price is CA $206
CA $337 total
includes taxes & fees
Aug 12 - Aug 13
Serenity South -- Gardens, River-Views, and Refreshing Space

The Twisted Sassafras Treehouse

10.0 out of 10, Exceptional, (19)
"My wife and I thoroughly enjoyed our stay here! A beautiful place built on a beautiful property; we enjoyed the hot tub under the stars and the morning coffee on the porch (and another hot tub ). Great place for some R&R, and excellent communication with the owner in advance. Wouldn’t hesitate to book again."
The price is CA $284
CA $415 total
includes taxes & fees
Aug 25 - Aug 26
The Twisted Sassafras Treehouse

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

10.0 out of 10, Exceptional, (219)
"This is our second time staying at the Kage House. Didnt disappoint at all. Great location! "
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (37)
"Great for a family that is visiting their SEMO student! Great location! Plenty of amenities!"
Quaint, Beautiful Home next to SEMO and Hospital

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

9.8 out of 10, Exceptional, (37)
"Nice place to stay! Clean, able to walk to everything!"
The price is CA $113
CA $190 total
includes taxes & fees
Aug 17 - Aug 18
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Gorgeous 1856 Log Cabin, Completely Renovated

10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
The price is CA $275
CA $427 total
includes taxes & fees
Aug 12 - Aug 13
Gorgeous 1856 Log Cabin, Completely Renovated

Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable

10.0 out of 10, Exceptional, (1)
"Great location and the one issue was resolved quickly and no fault of the property owner. "
Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable

Super cute family friendly 3-bedroom house in Cape Girardeau with AC, WiFi

Super cute family friendly 3-bedroom house in Cape Girardeau with AC, WiFi

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (33)
"all was so nice and we enjoyed our stay. grandkids and us loved having pool table and card games and all the peace and quiet there. thank u again for contacting me and giving us address. we appreciated that very much. "
The price is CA $246
CA $369 total
includes taxes & fees
Aug 24 - Aug 25
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Charming Secluded Getaway Cabin within minutes of amenities

10.0 out of 10, Exceptional, (15)
"Nice little Cabin in a beautiful area. Blair and her family were wonderful!"
Charming Secluded Getaway Cabin within minutes of amenities

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

8.6 out of 10, Excellent, (17)
"We stayed here with my cousins family while our daughters were playing at Sportplex. Nice and clean property. Host was easy to communicate with. Would stay here again when in this area. "
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.4 out of 10, Exceptional, (6)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
The price is CA $433
CA $677 total
includes taxes & fees
Aug 24 - Aug 25
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Urban 2-bedroom Escape in Downtown Cape Girardeau

10.0 out of 10, Exceptional, (3)
"We had the best girls’ getaway here! The place was super clean and well decorated. We had everything we needed, and the host was friendly and quick to respond. The location was perfect—lots of shops, restaurants, and even a spa all within walking distance. We couldn’t have asked for a better spot!"
Urban 2-bedroom Escape in Downtown Cape Girardeau

The Cottage, Rusted Route Farms

10.0 out of 10, Exceptional, (1)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
The price is CA $172
CA $271 total
includes taxes & fees
Aug 12 - Aug 13
The Cottage, Rusted Route Farms

Beautiful location in the secluded woods

10.0 out of 10, Exceptional, (42)
"Our trip was to attend my son's graduation from SIU. The cabin was in an accessible spot to Carbondale and was great for the 5 of us. We enjoyed our stay!"
The price is CA $136
CA $246 total
includes taxes & fees
Aug 14 - Aug 15
Beautiful location in the secluded woods

New cabin in the woods with private hot tub

10.0 out of 10, Exceptional, (122)
"We absolutely love coming here. This was our 2nd stay and getting ready to book it for the fall again. "
New cabin in the woods with private hot tub

Peaceful secluded cabin located near Horseshoe Lake

9.8 out of 10, Exceptional, (14)
"This stay was comfortable and quiet an amazing weekend stay!!"
The price is CA $172
CA $276 total
includes taxes & fees
Aug 15 - Aug 16
Peaceful secluded cabin located near Horseshoe Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

Special Offer for Weekly & Monthly Stays in August & September at "Brickyard": This Cape Girardeau vacation home rental is located on a river and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Some other homes for rent in Cape Girardeau include Serenity South -- Gardens, River-Views, and Refreshing Space and Little Blue Cottage on Spanish.

How many vacation rentals will I find in Cape Girardeau?

Choose from 18 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.