Title: Top Hotels in Cape Girardeau County | Expedia.ca

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![Beautiful city by the Mississippi River](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Alice Burghart

# Search Cape Girardeau County Hotels

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## Top Cities in Cape Girardeau County

![](https://mediaim.expedia.com/destination/2/5b27a574bbd8c4a139204e48a625a1c7.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Cape Girardeau

[](https://expedia.ca/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)

## Check prices for these dates

Tonight

[Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Cape Girardeau County hotels

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(1001)

"Great place and staff, very accommodating!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Megan

CA $123

CA $139 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Riverview Two Queen Room](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Jackpot Suite | Living area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Riverview

[](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(476)

"The room was clean and the mattress was extremely comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stacy

CA $132

CA $149 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

Jackson

8.8/10

Excellent

(674)

"Great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

GUY

CA $115

CA $125 total

includes taxes & fees

Jan 7 - Jan 8, 2026

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/b5f01af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

Jackson

9.6/10

Exceptional

(1010)

"Breakfast was great- staff was welcoming. Will stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $114

CA $120 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/f7d52bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/c3df8884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Cape Girardeau by IHG

[](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

Cape Girardeau

8.2/10

Very good

(885)

"Room was clean and spacious."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

George

CA $106

CA $127 total

includes taxes & fees

Jan 21 - Jan 22, 2026

[](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/59c49f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/05842f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f29b08e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

Cape Girardeau

9.0/10

Wonderful

(1000)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heather

CA $96

CA $108 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/006e0795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

Cape Girardeau

9.0/10

Wonderful

(1003)

"Nice place for a stay at a reasonable price."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Arthur

CA $96

CA $108 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed with Sofa bed, Accessible, Refrigerator & Microwave (2 Rooms, Tub)](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/0f190cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(1000)

"Very friendly staff and great breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ray

CA $123

CA $139 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/44b66206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cape Girardeau North

[](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

Cape Girardeau

7.2/10

Good

(686)

"Overall was wonderful customer service and breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie

CA $79

CA $89 total

includes taxes & fees

Dec 30 - Dec 31

[](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/182edc95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(1000)

"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian

CA $125

CA $141 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru By Hilton Cape Girardeau

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(103)

"It was a nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Douglas

CA $123

CA $140 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/e6e29f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/051de21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/81fbb6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Cape Girardeau I 55 East

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(785)

"Excellent stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christina

CA $140

CA $158 total

includes taxes & fees

Dec 30 - Dec 31

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/c7d69739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Cape Girardeau Downtown

[](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(468)

"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah

CA $160

CA $181 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Cape Girardeau

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(142)

"Nice hotel, clean and comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $121

CA $137 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information)

![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Town House Inn

[](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

Jackson

7.6/10

Good

(425)

"The staff member Tim was very friendly and nice. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julie

CA $87

CA $95 total

includes taxes & fees

Dec 31 - Jan 1, 2026

[](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/464a0039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking (NRF)](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/f2b68c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Town House Inn Cape Giradreau

[](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information)

Cape Girardeau

6.0/10

(206)

"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

CA $75

CA $88 total

includes taxes & fees

Jan 7 - Jan 8, 2026

[](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/8a502333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Jackson-Cape Girardeau

[](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

Jackson

8.2/10

Very good

(740)

"Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lori

CA $110

CA $119 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Suite, 2 Bedrooms, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fd5c34e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/9f324b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a236a8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rockwood Inn

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information)

Cape Girardeau

10/10

Exceptional

(18)

"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vanessa

CA $190

CA $215 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/3867ac72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Little Blue Cottage on Spanish

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

Cape Girardeau

8.6/10

Excellent

(48)

"I would definitely stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bonita

CA $111

CA $138 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/e90509fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/44505503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/9000af4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/379d384a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Artistic-Indoor-Swing-2-Blocks-To-Downtown.h71736900.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(45)

"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jordan S.

CA $112

CA $189 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Artistic-Indoor-Swing-2-Blocks-To-Downtown.h71736900.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08&regionId=553248635976430467&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Great weekend hotel deals in Cape Girardeau County, MO

Showing deals for:**Jan 2 - Jan 4**

### Image gallery for The Riverview

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Riverview

Cape Girardeau

**9.4/10**Exceptional (476 reviews)

10% off

CA $206

CA $464 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-04&selected=105081384&adults=2)

### Image gallery for Rockwood Inn

![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Rockwood Inn

Cape Girardeau

**10/10**Exceptional (18 reviews)

10% off

CA $271

CA $613 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-04&selected=105486893&adults=2)

### Image gallery for Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/e90509fa.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau

**9.4/10**Exceptional (45 reviews)

10% off

CA $147

CA $392 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-04&selected=71736900&adults=2)

### Image gallery for Urban 2-bedroom Escape in Downtown Cape Girardeau 

![Exterior detail](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/23d7d447.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Urban 2-bedroom Escape in Downtown Cape Girardeau 

Cape Girardeau

**10/10**Exceptional (9 reviews)

10% off

CA $216

CA $622 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-04&selected=109929505&adults=2)

### Image gallery for Little Blue Cottage on Spanish

![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Little Blue Cottage on Spanish

Cape Girardeau

**8.6/10**Excellent (48 reviews)

10% off

CA $111

CA $253 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-04&selected=45712431&adults=2)

### Image gallery for Comfort Suites Jackson-Cape Girardeau

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Comfort Suites Jackson-Cape Girardeau

Jackson

**8.2/10**Very good (740 reviews)

20% off

CA $126

CA $273 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-04&selected=2555896&adults=2)

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## Top Cape Girardeau County Hotel Reviews

![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg)

### Tru By Hilton Cape Girardeau

10/10 Excellent

"Hotel was very clean, quiet and has a great location! "

[](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![The Twisted Sassafras Treehouse ](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/55527a20_y.jpg)

### The Twisted Sassafras Treehouse 

10/10 Excellent

"Beautiful space indoors and out, can’t wait to come back when the weather allows more time for the outdoor amenities! "

[](https://expedia.ca/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Breakfast great hot and big variety "

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Comfort Suites Jackson-Cape Girardeau](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25_y.jpg)

### Comfort Suites Jackson-Cape Girardeau

10/10 Excellent

"Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. "

[](https://expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg)

### Town House Inn

10/10 Excellent

"Everything was excellent and comfortable beds "

[](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Didn’t eat the breakfast but I’m sure it is wonderful. Everything from the Check in process to the condition of the rooms to the comfort of the stay was worth the money "

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg)

### Quality Inn

10/10 Excellent

"Comfortable bed"

[](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Very clean premises, easy check-in, quiet, good breakfast and Wendy, the receptionist was the BEST ever in providing professional, quality and attentive customer service with a smile and warm welcome!"

[](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg)

### Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"Room was clean and spacious."

[](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

## Explore a world of travel with Expedia

- Explore a world of travel with Expedia

### Top cities in Cape Girardeau County

- [Cape Girardeau Hotels ](https://expedia.ca/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)
- [Jackson Hotels ](https://expedia.ca/Jackson-Hotels.d55765.Travel-Guide-Hotels)
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### More Accommodation Types in Cape Girardeau County

- [Vacation Homes in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Private-Vacation-Homes.d553248635976430467-aaPrivateVacationHomes.Travel-Guide-Accommodation)
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- [Cottages in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Cottages.d553248635976430467-aaCottages.Travel-Guide-Accommodation)
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- [RV Parks in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-RV-Parks.d553248635976430467-aaRVParks.Travel-Guide-Accommodation)
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- [Motels in Cape Girardeau County ](https://expedia.ca/Cape-Girardeau-County-Motels.d553248635976430467-aaMotels.Travel-Guide-Accommodation)
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### Explore more hotels

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- [Drury Inn & Suites Jackson MO ](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)
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- [Pear Tree Inn Cape Girardeau Near the Medical Center ](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)
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- [Pear Tree Inn Cape Girardeau West ](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

[See a list of all hotels in Cape Girardeau County](https://expedia.ca/All-Cape-Girardeau-County-Hotels.d553248635976430467.Travel-Guide-City-All-Hotels)

### More ways to book

- [Book Hotels in Cape Girardeau County on Expedia.com ](https://www.expedia.com/Destinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations)

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- [Cheap Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Cheap-Hotels.0-0-d178304-tCheapHotels.Hotel-Filter-Destinations)
- [Hotels in Power and Light District](https://expedia.ca/Power-And-Light-District-Kansas-City-Hotels.0-n6162504-0.Travel-Guide-Filter-Hotels)
- [Hotels in Downtown Kansas City](https://expedia.ca/Downtown-Kansas-City-Kansas-City-Hotels.0-n6058828-0.Travel-Guide-Filter-Hotels)
- [Beach Hotel in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Beach-Hotel.0-0-d178304-tBeachHotel.Hotel-Filter-Destinations)

Flights

- [Cheap Flights to Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Flight-Destinations)
- [Cheap Flights to San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Flight-Destinations)

Cars

- [Car rentals in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Car-Rental-Destinations)
- [Car rental Kansas City Airport (MCI)](https://expedia.ca/Car-Rentals-In-Kansas-City-Intl.d4801357.Car-Rental-Guide)

Cruises

- [Cruises from San Diego County](https://expedia.ca/Cruises-from-San-Diego-County.d178304.Cruise-Departure-Port)

Activities

- [Things to do in Baldwin County](https://expedia.ca/Things-To-Do-In-Baldwin-County.d553248635976432245.Travel-Guide-Activities)
- [Things to do in San Diego County](https://expedia.ca/Things-To-Do-In-San-Diego-County.d178304.Travel-Guide-Activities)
- [Things to do in High Ridge](https://expedia.ca/Things-To-Do-In-High-Ridge.d553248634983579370.Travel-Guide-Activities)
- [Things to do in Orange County](https://expedia.ca/Things-To-Do-In-Orange-County.d603224.Travel-Guide-Activities)
- [Things to do in Levy County](https://expedia.ca/Things-To-Do-In-Levy-County.d553248635976432502.Travel-Guide-Activities)

Packages

- [San Diego County Vacation Packages](https://expedia.ca/San-Diego-County.d178304.Destination-Travel-Guides)

General

- [Visit Downtown St. Louis](https://expedia.ca/St-Louis-Downtown-St-Louis.dx800136)
- [Visit Downtown Kansas City](https://expedia.ca/Kansas-City-Downtown-Kansas-City.dx6058828)
- [Visit Parkville](https://expedia.ca/Parkville.dx9973)
- [Visit Orange County](https://expedia.ca/Orange-County.dx603224)

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