- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Top cities in Cape Girardeau County

Cape Girardeau
Check prices for these dates
Our top choices for Cape Girardeau County hotels

1. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
The price is CA $143
CA $161 total
includes taxes & fees
Nov 18 - Nov 19

2. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (704 reviews)
The price is CA $155
CA $175 total
includes taxes & fees
Nov 23 - Nov 24

3. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,004 reviews)
The price is CA $103
CA $116 total
includes taxes & fees
Nov 23 - Nov 24

4. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is CA $128
CA $145 total
includes taxes & fees
Nov 24 - Nov 25

5. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (897 reviews)
The price is CA $114
CA $123 total
includes taxes & fees
Nov 22 - Nov 23

6. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is CA $136
CA $154 total
includes taxes & fees
Dec 13 - Dec 14

7. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
The price is CA $114
CA $121 total
includes taxes & fees
Dec 6 - Dec 7

8. Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.0 out of 10, Good, (823 reviews)
The price is CA $85
CA $96 total
includes taxes & fees
Nov 22 - Nov 23

9. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.0 out of 10, Very good, (1,001 reviews)
The price is CA $98
CA $119 total
includes taxes & fees
Nov 25 - Nov 26

10. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is CA $122
CA $138 total
includes taxes & fees
Dec 6 - Dec 7

11. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (562 reviews)
The price is CA $166
CA $188 total
includes taxes & fees
Nov 29 - Nov 30

12. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (201 reviews)
The price is CA $122
CA $138 total
includes taxes & fees
Nov 23 - Nov 24

13. Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
6.2 out of 10, (244 reviews)
The price is CA $100
CA $117 total
includes taxes & fees
Nov 16 - Nov 17

14. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (861 reviews)
The price is CA $139
CA $157 total
includes taxes & fees
Dec 6 - Dec 7

15. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.0 out of 10, Very good, (785 reviews)
The price is CA $108
CA $116 total
includes taxes & fees
Dec 13 - Dec 14

16. Town House Inn
Town House InnJackson
7.6 out of 10, Good, (451 reviews)
The price is CA $113
CA $122 total
includes taxes & fees
Nov 15 - Nov 16

17. Little Blue Cottage on Spanish
Little Blue Cottage on SpanishCape Girardeau
8.4 out of 10, Very good, (59 reviews)
The price is CA $116
CA $143 total
includes taxes & fees
Nov 16 - Nov 17

18. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Romantic Creekside Retreat | Fireplace | Deck | Pet FriendlyCape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
The price is CA $221
CA $310 total
includes taxes & fees
Nov 18 - Nov 19

19. The Little Cape Lofted Cottage | Creek & Nature
The Little Cape Lofted Cottage | Creek & NatureCape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
The price is CA $230
CA $306 total
includes taxes & fees
Nov 16 - Nov 17

20. The Little Château | Woodland Escape
The Little Château | Woodland EscapeCape Girardeau
The price is CA $221
CA $297 total
includes taxes & fees
Nov 16 - Nov 17
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Cape Girardeau County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau






































































