Title: Book The Best Hotels in Chaffee, MO for 2025 from CA $83 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Chaffee](https://expedia.ca/Chaffee-Vacation-Rentals.d553248634983269107.Travel-Guide-VacationRentals)[Chaffee Car Rentals](https://expedia.ca/Car-Rentals-In-Chaffee.d553248634983269107.Car-Rental-Guide)[Chaffee Vacation Packages](https://expedia.ca/Chaffee.d553248634983269107.Destination-Travel-Guides) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Abbie Moon # Find hotels in Chaffee, MO from CA $83 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Chaffee Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=PETS) ## Check prices for these dates Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 103 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston Sikeston 7.2/10 Good (1004) "Staff were great." CA $88 CA $100 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (398) "Nice property and friendly staff." CA $133 CA $150 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1018) "Was a clean room, nice staff, good parking " CA $125 CA $133 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1007) "I love this hotel! Have stayed several times and will definitely stay again. The rooms are always very clean and the staff is so friendly and helpful. I highly recommend this hotel!" CA $107 CA $123 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (431) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." CA $146 CA $166 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1013) "This is such a nice clean place to stay. Breakfast was really good and the staff so nice and helpful. " CA $114 CA $130 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (625) "Friendly staff, very clean and pleasant environment." CA $117 CA $127 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/8e494fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/2dc19e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/3727e01c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (682) "This is a great place to stay and the staff are super friendly. The manager helped me with a double booking issue and was able to get me a refund which is amazing! Good clean place to stay." CA $72 CA $83 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area Sikeston 6.6/10 (556) "I enjoyed our stay" CA $87 CA $100 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1013) "Everything was extremely nice" CA $125 CA $144 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (414) "It was easy and quiet and an easy check in " CA $79 CA $86 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1012) "My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there." CA $98 CA $110 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1009) "Staff was friendly, room was clean, good location, good rate." CA $98 CA $110 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1001) "It was right off the interstate with lots of restaurant options " CA $132 CA $149 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/b77bd903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5641af73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/af525dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 Sikeston 8.4/10 Very good (271) "The facility was very nice. " CA $123 CA $140 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1001) "Excellent place. Really friendly staff" CA $125 CA $141 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1021) "Very nice hotel and nice staff " CA $125 CA $141 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (451) "The Staff was friendly The restaurant was good" CA $174 CA $197 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.4/10 Exceptional (25) "Hotel was clean, the toilets could use some attention, but staff was friendly and the breakfast was good" CA $141 CA $159 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (643) "nice stay" CA $84 CA $95 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12®ionId=553248634983269107&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ## Learn more about Chaffee Venture to Isle Casino Cape Girardeau and Show Me Center—just two of the sights around Chaffee. [See all hotels in Chaffee](https://www.expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12&adults=2®ionId=553248634983269107) ![](https://mediaim.expedia.com/destination/2/c1b2471b51fb6a0569864d8f0d95d9a4.jpg?impolicy=fcrop&w=624&h=770&p=1&q=high) Photo by Bailey Swinford ## More cheap stays in Chaffee ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO CA $172 CA $194 total Sep 28 - Sep 29 includes taxes & fees 9.2/10 Wonderful! (420 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St, Cape Girardeau, MO CA $98 CA $110 total Oct 5 - Oct 6 includes taxes & fees 8.8/10 Excellent! (1,008 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy, Cape Girardeau, MO CA $98 CA $110 total Oct 2 - Oct 3 includes taxes & fees 9/10 Wonderful! (1,007 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr, Sikeston, MO CA $88 CA $100 total Sep 29 - Sep 30 includes taxes & fees 7.2/10 Good! (1,003 reviews) [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Sikeston 120 S Interstate Drive, Sikeston, MO CA $114 CA $130 total Oct 12 - Oct 13 includes taxes & fees 8.2/10 Very Good! (1,009 reviews) [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive, Sikeston, MO CA $133 CA $150 total Oct 12 - Oct 13 includes taxes & fees 8.8/10 Excellent! (397 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ## Recent reviews of Chaffee hotels ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 5/5 Excellent "Very, Very nice. Always, first think I look at is landscaping. It foretells that attitude of the hotel. Drury of the Cape was nicely done, well maintained and fresh. Ok, good start. Start check in and Travelocity computer was not up to speed with Drury's. Desk person got manager, sorted it in just a few short minutes, with a smile the whole time, and up to my room. Room was immaculate, well appointed, nicely decorated, and just plain comfortable. Relaxed a few minutes in the comfortable chair and went down for complimentary dinner. No gigantic spread but, way more than I expected and very tasty. Eveything about my stay was over the top for the price I paid. Everyone working there seemed happy and smiling genuinely.Absolutely one of the nicest hotels I've ever stayed in. This company has the right idea on providing service while not trying to rob you at the same time. Thank You!" A verified traveller from VANCLEAVE stayed at Drury Plaza Hotel Cape Girardeau Conference Center Posted 3 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 5/5 Excellent "Staff was friendly, room was clean, good location, good rate." A verified traveller stayed at Pear Tree Inn Cape Girardeau Near the Medical Center Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 5/5 Excellent "this place is awesome! evening snacks and drinks (a meal really!) and very nice breakfast comfortable bed and beautiful grounds-quite rural, but Dairy Queen across the road. easy and safe seeming parking " A verified traveller stayed at Drury Inn & Suites Jackson MO Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 5/5 Excellent Definitely recommend "Very clean, sincerely friendly staff and very helpful. Pillows and bed comfy. Great location. " A verified traveller stayed at Pear Tree Inn Cape Girardeau West Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 5/5 Excellent "Brand new hotel and it’s not even shown on Google maps. Great condition and service!" A verified traveller stayed at Tru By Hilton Cape Girardeau Posted 6 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 5/5 Excellent "My husband and I love this hotel. We stay here every single time we are in the area. While it’s a little pricier than a few other options it is definitely worth it for us. The hotel is beautiful and the staff is always very accommodating. Emily and the rest of the staff are so sweet and helpful. We will be back soon and can’t wait! " A verified traveller stayed at Courtyard by Marriott Cape Girardeau Downtown Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 5/5 Excellent "Very comfortable bed for people with back issues" A verified traveller from BOURBON stayed at Pear Tree Inn Sikeston Posted 7 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Hampton Inn Cape Girardeau I 55 East](//images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 5/5 Excellent "Good" A verified traveller stayed at Hampton Inn Cape Girardeau I 55 East Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 5/5 Excellent "Always a nice place to stay!" A verified traveller stayed at Drury Inn & Suites Sikeston, MO Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Chaffee hotel for you. ### How can I save on a Chaffee hotel booking with Expedia? > Before booking your Chaffee hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Chaffee hotel? > Prices for hotels in Chaffee often vary, but you can find a great deal from CA $83 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)