Title: Book The Best Hotels in Chaffee, MO for 2026 from CA $98 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Chaffee](https://expedia.ca/Chaffee-Vacation-Rentals.d553248634983269107.Travel-Guide-VacationRentals)[Chaffee Car Rentals](https://expedia.ca/Car-Rentals-In-Chaffee.d553248634983269107.Car-Rental-Guide)[Chaffee Vacation Packages](https://expedia.ca/Chaffee.d553248634983269107.Destination-Travel-Guides) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Abbie Moon # Find hotels in Chaffee, MO from CA $98 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Chaffee Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&amenities=PETS) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&lodging=APARTMENT) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&amenities=WATER_PARK) ## Check prices for these dates Tonight [Jan 1 - Jan 2](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2026-01-01&endDate=2026-01-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 2 - Jan 3](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2026-01-02&endDate=2026-01-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248634983269107&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Chaffee hotels ![Standard Room, 1 Queen Bed, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/eaa414ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/dbe031d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a102ce70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) Cape Girardeau 10/10 Exceptional (19) "My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $208 CA $235 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/7adb4452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking (NRF)](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/5d555857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Cape Girardeau 6.0/10 (206) "Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $75 CA $88 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/e322869e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/4de18ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG [](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) Cape Girardeau 8.2/10 Very good (886) "Room was clean and spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $96 CA $116 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1005) "Awesome stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breckin CA $123 CA $139 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (689) "The room was clean and nice. The breakfast was really good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kalani CA $81 CA $92 total includes taxes & fees Jan 8 - Jan 9 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (145) "Lovely staff clean hotel comfortable beds " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kastriot CA $121 CA $136 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (104) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $123 CA $140 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1004) "Nice place for a stay at a reasonable price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arthur CA $96 CA $108 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/363ef183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (481) " Excellent stay. Will come again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joydeep CA $131 CA $148 total includes taxes & fees Jan 2 - Jan 3 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/acc0b9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/4c2e6495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/cfaba55a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (785) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina CA $145 CA $163 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/a0829ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel [](https://www.expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) Marble Hill 9.6/10 Exceptional (84) "Cute room, great food, fun soda fountain and friendly owners! Will return! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie [](https://www.expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (471) "Very nice hotel within walking distance to many good restaurants " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $156 CA $177 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1000) "We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $125 CA $141 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1006) "This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $123 CA $139 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (426) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $80 CA $87 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very good (740) "Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $109 CA $118 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1004) "Great place. Friendly staff clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff CA $123 CA $142 total includes taxes & fees Jan 6 - Jan 7 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1001) "Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen CA $96 CA $108 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 8.8/10 Excellent (681) "Conveniently located, clean, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip CA $111 CA $120 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (456) "clean room, comfy bedding, nice staff, convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexa CA $140 CA $158 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-15&endDate=2026-01-16®ionId=553248634983269107&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ## Learn more about Chaffee Venture to Isle Casino Cape Girardeau and Show Me Center—just two of the sights around Chaffee. [See all hotels in Chaffee](https://www.expedia.ca/Hotel-Search?startDate=2026-01-15&endDate=2026-01-16&adults=2®ionId=553248634983269107) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=324&h=432&p=1&q=high) Photo by Abbie Moon ## More cheap stays in Chaffee ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO CA $86 CA $98 total Jan 27 - Jan 28 includes taxes & fees 7.2/10 Good! (1,002 reviews) [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO CA $96 CA $108 total Jan 20 - Jan 21 includes taxes & fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St Cape Girardeau MO CA $96 CA $108 total Jan 5 - Jan 6 includes taxes & fees 8.8/10 Excellent! (1,002 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Candlewood Suites Cape Girardeau by IHG 485 S Mount Auburn Rd Cape Girardeau MO CA $96 CA $116 total Jan 11 - Jan 12 includes taxes & fees 8/10 Very Good! (886 reviews) [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO CA $125 CA $141 total Jan 11 - Jan 12 includes taxes & fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO CA $140 CA $158 total Jan 11 - Jan 12 includes taxes & fees 8.8/10 Excellent! (452 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ## Hotels in Chaffee with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 8 properties [](https://expedia.ca/3Star-Chaffee-Hotels.s30-0-d553248634983269107.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 28 properties [](https://expedia.ca/2Star-Chaffee-Hotels.s20-0-d553248634983269107.Travel-Guide-Filter-Hotels) ## Recent reviews of Chaffee hotels ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 5/5 Excellent "Not a bad place to stay" A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Posted 1 day ago [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 5/5 Excellent "The room was clean and staff friendly and helpful. Very nice for the price. No complaints. And appreciated the hot breakfast and sweet hostess." A verified traveller stayed at Pear Tree Inn Cape Girardeau West Posted 1 day ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 5/5 Excellent "This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! " A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center Posted 3 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 5/5 Excellent "The evening kick back is always awesome. Miranda was helpful and kind." A verified traveller stayed at Drury Inn & Suites Jackson MO Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 5/5 Excellent "Breakfast was fresh. Room was clean. Pool lovely. " A verified traveller stayed at Fairfield Inn & Suites by Marriott Cape Girardeau Posted 6 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 5/5 Excellent "Everything was wonderful. Staff (especially Debbie) was the best. This is a nice quiet comfortable pplace to stay" A verified traveller stayed at Pear Tree Inn Cape Girardeau Near the Medical Center Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 5/5 Excellent "Great place to stay to stop over for the night. Very clean. Great value. " A verified traveller stayed at Best Western Plus Sikeston Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 5/5 Excellent "Clean and very nice room " A verified traveller stayed at Drury Inn & Suites Cape Girardeau Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 5/5 Excellent "clean room, comfy bedding, nice staff, convenient location " A verified traveller stayed at Hampton Inn Sikeston Posted 9 days ago [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Chaffee hotel booking with Expedia? ### How much is the nightly rate at a Chaffee hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [B&B in Advance ](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Advance ](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [Advance Hotels ](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Lodges in Advance ](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance ](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - [Apartments in Bell City ](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - [Cheap Hotels in Benton ](https://www.expedia.ca/Benton-Hotels-Cheap-Hotels.0-0-d553248634983369680-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Benton ](https://www.expedia.ca/Benton-Hotels-Luxury-Hotel.0-0-d553248634983369680-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Benton Hotels ](https://www.expedia.ca/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bertrand Hotels ](https://www.expedia.ca/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels ](https://www.expedia.ca/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomfield Hotels ](https://www.expedia.ca/Bloomfield-Hotels.d6351829.Travel-Guide-Hotels) - [Canalou Hotels ](https://www.expedia.ca/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Rv Parks in Cape Girardeau County ](https://www.expedia.ca/Cape-Girardeau-County-RV-Parks.d553248635976430467-aaRVParks.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-All-Inclusive-Hotel.0-0-d820-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Boutique-Hotel.0-0-d820-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Casino-Hotel.0-0-d820-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Cheap-Hotels.0-0-d820-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Hotel-With-Pool.0-0-d820-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Hotels-With-Bar.0-0-d820-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d820-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Hotels-With-Indoor-Pool.0-0-d820-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Oceanfront-Hotels.0-0-d820-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Pet-Friendly-Hotel.0-0-d820-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Romantic-Hotel.0-0-d820-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Hotels-Spa-Hotel.0-0-d820-tSpaHotel.Travel-Guide-Filter-Hotels) - [Cape Girardeau Hotels ](https://www.expedia.ca/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Inns in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-Inns.d820-aaInns.Travel-Guide-Accommodation) - [Rv Parks in Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau-RV-Parks.d820-aaRVParks.Travel-Guide-Accommodation) - [Hotels near Cape Rock Park ](https://www.expedia.ca/Cape-Rock-Park-Hotels.0-l553248621532655781-0.Travel-Guide-Filter-Hotels) - [Charleston Hotels ](https://www.expedia.ca/Charleston-Hotels.d7182.Travel-Guide-Hotels) - [Cabin Rentals in Commerce ](https://www.expedia.ca/Commerce-Cabins.d553248634983177483-aaCabins.Travel-Guide-Accommodation) - [Mississippi County Hotels ](https://www.expedia.ca/Destinations-In-Mississippi-County.d553248635976432410.Hotel-Destinations) - [Dexter Hotels ](https://www.expedia.ca/Dexter-Hotels.d55097.Travel-Guide-Hotels) - [Dudley Hotels ](https://www.expedia.ca/Dudley-Hotels.d553248634983299889.Travel-Guide-Hotels) - [Hotels near eDen Spa & Salon ](https://www.expedia.ca/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels) - [East Prairie Hotels ](https://www.expedia.ca/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels) - [Essex Hotels ](https://www.expedia.ca/Essex-Hotels.d553248634983169000.Travel-Guide-Hotels) - [Hotels with a Pool in Fruitland ](https://www.expedia.ca/Fruitland-Hotels-Hotel-With-Pool.0-0-d553248635975866670-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Fruitland Hotels ](https://www.expedia.ca/Fruitland-Hotels.d553248635975866670.Travel-Guide-Hotels) - [Motels in Fruitland ](https://www.expedia.ca/Fruitland-Motels.d553248635975866670-aaMotels.Travel-Guide-Accommodation) - [Glen Allen Hotels ](https://www.expedia.ca/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Hotels near Isle Casino Cape Girardeau ](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels) - [B&B in Jackson ](https://www.expedia.ca/Jackson-Bed-And-Breakfast.d55765-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Free Breakfast in Jackson ](https://www.expedia.ca/Jackson-Hotels-Hotels-With-Free-Breakfast.0-0-d55765-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Jackson ](https://www.expedia.ca/Jackson-Hotels-Hotels-With-Hot-Tubs.0-0-d55765-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Jackson ](https://www.expedia.ca/Jackson-Hotels-Hotels-With-Kitchenettes.0-0-d55765-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Jackson ](https://www.expedia.ca/Jackson-Hotels-Pet-Friendly-Hotel.0-0-d55765-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Jackson Hotels ](https://www.expedia.ca/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Palaces in Jackson ](https://www.expedia.ca/Jackson-Palaces.d55765-aaPalaces.Travel-Guide-Accommodation) - [B&B in Kelso ](https://www.expedia.ca/Kelso-Bed-And-Breakfast.d553248634983171130-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Marble Hill ](https://www.expedia.ca/Marble-Hill-Hotels-Cheap-Hotels.0-0-d3000445212-tCheapHotels.Travel-Guide-Filter-Hotels) - [Marble Hill Hotels ](https://www.expedia.ca/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Matthews Hotels ](https://www.expedia.ca/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Miner Hotels ](https://www.expedia.ca/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Morehouse Hotels ](https://www.expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [B&B in Oran ](https://www.expedia.ca/Oran-Bed-And-Breakfast.d3000445386-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with a Pool in Oran ](https://www.expedia.ca/Oran-Hotels-Hotel-With-Pool.0-0-d3000445386-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Oran ](https://www.expedia.ca/Oran-Hotels-Luxury-Hotel.0-0-d3000445386-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oran Hotels ](https://www.expedia.ca/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Inns in Oran ](https://www.expedia.ca/Oran-Inns.d3000445386-aaInns.Travel-Guide-Accommodation) - [Hotels near Perryville Country Club ](https://www.expedia.ca/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels) - [Puxico Hotels ](https://www.expedia.ca/Puxico-Hotels.d553248634983343452.Travel-Guide-Hotels) - [Cheap Hotels in Scott City ](https://www.expedia.ca/Scott-City-Hotels-Cheap-Hotels.0-0-d553248634983544376-tCheapHotels.Travel-Guide-Filter-Hotels) - [Scott City Hotels ](https://www.expedia.ca/Scott-City-Hotels.d553248634983544376.Travel-Guide-Hotels) - [Sikeston Hotels ](https://www.expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Hotels near Southeast Missouri State University ](https://www.expedia.ca/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Wilson City Hotels ](https://www.expedia.ca/Wilson-City-Hotels.d553248634983391595.Travel-Guide-Hotels) - [Flights to Cape Girardeau ](https://www.expedia.ca/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights) - [Flights to Jackson ](https://www.expedia.ca/Cheap-Flights-To-Jackson.d55765.Travel-Guide-Flights) - [Flights from Commerce ](https://www.expedia.ca/lp/flights/553248634983177483/flights-from-commerce) - [Flights from Scott City ](https://www.expedia.ca/lp/flights/553248634983544376/flights-from-scott-city) - [Flights from Cape Girardeau ](https://www.expedia.ca/lp/flights/820/flights-from-cape-girardeau) - [Flights from Accra (ACC) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/acc/cgi/accra-to-cape-girardeau) - [Flights from Bloomington (BMI) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/bmi/cgi/bloomington-to-cape-girardeau) - [Flights from Buffalo (BUF) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/buf/cgi/buffalo-to-cape-girardeau) - [Flights from Colombo (CMB) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/cmb/cgi/colombo-to-cape-girardeau) - [Flights from Dhaka (DAC) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/dac/cgi/dhaka-to-cape-girardeau) - [Flights from Detroit (DTW) to Sikeston (SIK) ](https://www.expedia.ca/lp/flights/dtw/sik/detroit-to-sikeston) - [Flights from Grand Island (GRI) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/gri/cgi/grand-island-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from Las Vegas (LAS) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/las/cgi/las-vegas-to-cape-girardeau) - [Flights from Ocala (OCF) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/ocf/cgi/ocala-to-cape-girardeau) - [Flights from Pierre (PIR) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/pir/cgi/pierre-to-cape-girardeau) - [Flights from St. Louis (STL) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Edmonton (YEG) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/yeg/cgi/edmonton-to-cape-girardeau) - [Flights from Toronto (YTO) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/yto/cgi/toronto-to-cape-girardeau) - [Flights from Montreal (YUL) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/yul/cgi/montreal-to-cape-girardeau) - [Flights from Vancouver (YVR) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/yvr/cgi/vancouver-to-cape-girardeau) - [Flights from Winnipeg (YWG) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/ywg/cgi/winnipeg-to-cape-girardeau) - [Flights from Calgary (YYC) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/yyc/cgi/calgary-to-cape-girardeau) - [Flights from Toronto (YYZ) to Cape Girardeau (CGI) ](https://www.expedia.ca/lp/flights/yyz/cgi/toronto-to-cape-girardeau) - [Visit Cape Girardeau ](https://www.expedia.ca/Cape-Girardeau.dx820) - [Eden Spa & Salon ](https://www.expedia.ca/EDen-Spa-Salon-Cape-Girardeau.d553248621532655776.Vacation-Attraction) - [Southeast Missouri State University ](https://www.expedia.ca/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) - [Rental cars Cape Girardeau Municipal airport ](https://www.expedia.ca/Car-Rentals-In-Cape-Girardeau-Municipal.d6026978.Car-Rental-Guide) - [Car rental Cape Girardeau ](https://www.expedia.ca/Car-Rentals-In-Cape-Girardeau.d820.Car-Rental-Guide) - [Car rentals near Cape Girardeau County ](https://www.expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Rental-Destinations) - [Hertz Rental Cars in Marble Hill ](https://www.expedia.ca/Hertz-Car-Rentals-In-Marble-Hill.d3000445212-c40.Car-Rental-Guide-Suppliers) - [Marble Hill Vacation Rentals ](https://www.expedia.ca/Marble-Hill-Vacation-Rentals.d3000445212.Travel-Guide-VacationRentals) - [Book Hotels in Chaffee on Expedia.com ](https://www.expedia.com/Chaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app