Book The Best Hotels in Friedheim, MO for 2026 from CA $94 - Fully Refundable Options

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Our top choices for Friedheim hotels

A hotel room with a large bed, a TV on a wooden dresser, and a brick wall.

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

1. Drury Inn & Suites Jackson MO

Jackson

Lyn

CA $112

CA $119 total

includes taxes & fees

Oct 28 - Oct 29

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

2. Super 8 by Wyndham Perryville

Perryville

Matthew

CA $96

CA $109 total

includes taxes & fees

Nov 8 - Nov 9

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

An outdoor patio with tables and chairs, a stone wall, and large windows.

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

CA $112

CA $122 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A reception area with a counter, vending machines, and a security camera.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

4. Holiday Inn Express & Suites Perryville by IHG

Perryville

Perry

CA $142

CA $163 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

A kitchen with wooden cabinets, a dining area with a table and chairs, and various kitchen appliances.

5. Days Inn by Wyndham Perryville

Perryville

Jesse

CA $95

CA $109 total

includes taxes & fees

Oct 22 - Oct 23

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern retail area with a display of local items and snacks.

6. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

CA $126

CA $143 total

includes taxes & fees

Oct 29 - Oct 30

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

7. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

CA $106

CA $115 total

includes taxes & fees

Nov 10 - Nov 11

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A breakfast bar with a toaster, coffee maker, and fruit juice dispenser.

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

8. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

CA $90

CA $103 total

includes taxes & fees

Nov 10 - Nov 11

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A building with a sign that reads "The Atrium Boutique Hotel".

9. The Atrium - A Boutique Hotel

Perryville

Brian

CA $95

CA $109 total

includes taxes & fees

Oct 22 - Oct 23

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

10. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

CA $84

CA $94 total

includes taxes & fees

Nov 1 - Nov 2

A living room with a blue wall, a fireplace, a sofa, and a chair.

A brick building with a sign reading "Mercantile & Hotel".

A bar area with stools and a counter where a bartender is serving drinks.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

11. EC Reed's Mercantile and Hotel

Marble Hill

Jan

CA $148

CA $161 total

includes taxes & fees

Oct 22 - Oct 23

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

12. Perryville RV Resort

Perryville

Kevin

CA $93

CA $107 total

includes taxes & fees

Oct 22 - Oct 23

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

13. Town House Inn

Jackson

Jennifer

CA $100

CA $108 total

includes taxes & fees

Oct 22 - Oct 23

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

14. Urban Lofts

Perryville

Grace

CA $109

CA $227 total

includes taxes & fees

Oct 22 - Oct 23

A two-story house with a balcony, a front porch, and a well-maintained lawn.

A room with a white door, a radiator, a blue carpet, and a mural on the wall.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

15. The Mediterranean House 1858

Perryville

CA $104

CA $422 total

includes taxes & fees

Oct 22 - Oct 23

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Top Friedheim Hotel Reviews

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"LOVE the double bench available for 2 suitcases! Top notch, KUDOS on that little thing that meant so much to us as seniors. Breakfast was good, rooms were clean, restaurant was nice. An overall exceptional experience. This stay moved Holiday Inn Express up a few notches on my list."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Quick clean and very helpful"

Hot Tub & Creek Views: Secluded Perryville Cabin

8/10 Good

"This is a place that is very secluded with cell phone services being spotty. WiFi connections in the house were good but calling from the road was a bit challenging. This is a very rustic authentic piece of history"

Drury Inn & Suites Jackson MO

10/10 Excellent

"Lots of parking , clean room ,beautiful atmosphere breakfast was good."

Quality Inn Cape Girardeau North

10/10 Excellent

"I chose this motel due to it being close to the car rental agency I used and the bus stop for Greyhound. Sidewalks on Kingshighway would have helped but that is on the city of Cape Girardeau! :-}"

EC Reed's Mercantile and Hotel

10/10 Excellent

"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

Comfort Suites Jackson-Cape Girardeau

10/10 Excellent

"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"

Quality Inn Perryville I-55

8/10 Good

"Utilitarian hotel room. Clean, neat, well maintained. Refrigerators have freezer compartments. Outlets on lamp bases but no USB charging ports."