Cape Girardeau County Vacation Packages

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Your Cape Girardeau County Vacation

Travel on your own terms with a vacation package to Cape Girardeau County. Whether you're going for its family-friendly attractions, history, culture, or something else entirely, our package deals make travel planning hassle-free. You can expect to have a to-do list as long as your arm during your trip to Cape Girardeau County. One major city you'll want to spend some time in is Cape Girardeau. Quit dreaming and get packing, because your Cape Girardeau County vacation is only a few clicks away with Expedia.

Cape Girardeau County Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is CA $137 per night from Feb 12 to Feb 13
CA $137
CA $154 total
Feb 12 - Feb 13
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
We were in Cape Girardeau for our daughters, gymnastics meet at SEMO. On arrival we were greeted by the friendly staff. Check-in was easy. The room was very clean and warm being 15° outside as we are from Arizona and welcomed the warm building. Great showers very clean rooms. Everything was new. ...

Reviewed on Feb 3, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is CA $132 per night from Feb 10 to Feb 11
CA $132
CA $149 total
Feb 10 - Feb 11
includes taxes & fees
9.4/10 Exceptional! (499 reviews)
The hotel was so nice! We planned this trip for my husbands 40th birthday, and I called ahead to see if they did anything for birthdays and they gave us a complementary upgrade on our room. I was taken back on that and thought it was so kind and generous. I wasn’t expecting that - I would have been ...

Reviewed on Feb 1, 2026

The Riverview
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Feb 10 to Feb 11
CA $115
CA $125 total
Feb 10 - Feb 11
includes taxes & fees
8.8/10 Excellent! (700 reviews)
Clean room, friendly staff, good breakfast. The only complaint is neither of the water fountains in the fitness center work

Reviewed on Feb 6, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
See all 254 properties in Cape Girardeau County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Cape Girardeau County vacation package cost?
Perhaps less than you imagined — from a tempting , actually! By bundling hotels, flights and car rentals into your own customized travel package, your trip to Cape Girardeau County is just a few clicks away.
How do I get a cheap travel package to Cape Girardeau County?
Creating your own Cape Girardeau County vacation package with Expedia is one of the easiest ways to save. We have access to more than 550 air carriers and 1,000,000 properties spread across the globe. With such an awesome range to select from, you'll have no trouble creating your ideal trip.
What are the top hotels in Cape Girardeau County?
For hotels in Cape Girardeau with cozy beds and friendly service, you can't go past Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West. If you're swinging by Jackson as well, you can look forward to a relaxing night's sleep at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel or Auburn Place Hotel And Suites.
How far in advance should I book my Cape Girardeau County vacation?
Reserving your spot early with Expedia means one less thing to worry about. Most carriers advertise tickets up to 12 months in advance. Generally, this is the cheapest time to book. If circumstances have left you booking late, discount tickets to Cape Girardeau County sometimes occur in the weeks leading up to departure.
What does an Expedia Cape Girardeau County travel package include?
Choose from a combination of rental cars, hotels and flights. Once you've made your booking, you can add activities and tours. Want to pick your fare class? That's also possible. The choice is all yours when it comes to planning your perfect Cape Girardeau County getaway.
What should I know before booking a Cape Girardeau County travel package?
You'll save plenty with an Expedia travel package. Combine your flights, rental cars and hotels and land exciting discounts. Hotels aren't your only option, though. We have oceanfront condos, city apartments and everything in between!
Can I choose my airline with a Cape Girardeau County Expedia vacation package?
Definitely. Expedia has more than 550 airline partners to choose from around the world. With so much choice, finding the right carrier to bring you to Cape Girardeau County will be a breeze.
If I'm not able to travel, can I cancel my Cape Girardeau County vacation package?
Yes, you can. We realize life happens, so we're here to help if you have to make changes to your Cape Girardeau County vacation package. You may be able to cancel or amend your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.