
Jackson Vacation Packages
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Save up to CA $1,096 when you book a flight and hotel together*
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Your Jackson Vacation
Take the worry out of planning your next great adventure with a Jackson vacation package. Whether you're visiting for its cuisine, history, art or something else, this city offers limitless opportunities for discovery. Cape Girardeau Conservation Nature Center, Lazy L Safari Park and Steele Crest Winery are just a few of the many attractions worth visiting during your trip to Jackson. Expedia is here to help you escape the everyday. Tailor your vacation to Jackson to suit your travel style, whatever that may look like.
Jackson Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from Jul 20 to Jul 21
CA $135
CA $146 total
Jul 20 - Jul 21
includes taxes & fees
8.8/10 Excellent! (581 reviews)
"Our first room was stained, dirty, and not acceptable. I asked for another room and was given a room that looked like it was in another hotel altogether. It was clean, big, comfortable. Perfect. The staff was super friendly and helpful."
Reviewed on Jul. 4, 2025

Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Jul 20 to Jul 21
CA $123
CA $130 total
Jul 20 - Jul 21
includes taxes & fees
9.6/10 Exceptional! (1,005 reviews)
Weekend was just right
"Only issue was a little hair in the bath tub. Overall 5 star service will definitely be returning."
Reviewed on Jun. 30, 2025

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Jul 20 to Jul 21
CA $127
CA $138 total
Jul 20 - Jul 21
includes taxes & fees
8/10 Very Good! (719 reviews)
"Great area, fast check in, quiet, very spacious"
Reviewed on Jun. 29, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.