Title: 4 Stars Hotels in Downtown South San Francisco, San Francisco from CA $155 - Find Cheap Downtown South San Francisco Hotels With 4 Stars | Expedia.ca [Downtown South San Francisco Travel Guide](https://expedia.ca/San-Francisco-Downtown-South-San-Francisco.dx553248635976481411)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Downtown South San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-South-San-Francisco.d553248635976481411.Car-Rental-Guide)[Downtown South San Francisco Vacations](https://expedia.ca/Downtown-South-San-Francisco.d553248635976481411.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/725c89ab119e5e14f388d99a019f3224.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Catherine Edejer-McCormick # 4 Stars Hotels in Downtown South San Francisco, San Francisco from CA $155 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown South San Francisco 4 Star Hotels Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-11-02&endDate=2025-11-03&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-11-03&endDate=2025-11-04&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976481411&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown South San Francisco 4 Star Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Balcony](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/718197ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed (Ferry View)](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/e209fe62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/5b7dbc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Downtown San Francisco 9.2/10 Wonderful (1964) "Room was very clean View was good and Beautiful environment nice food service was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iqbal CA $251 CA $360 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Balcony, Bay View | Living area](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/a2b2e8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/01096013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Balcony, Bay View | Living area](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/9eb9cbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Francisco Financial District Downtown San Francisco 8.6/10 Excellent (1951) "Great restaurants near by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $150 CA $176 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/b020c7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/e62e0c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/2aabc067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Fisherman's Wharf Fisherman's Wharf 9.0/10 Wonderful (7022) "Wonderful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernestina CA $153 CA $238 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/db29a2e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/22520ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/9b58109d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Centric Fisherman's Wharf San Francisco Fisherman's Wharf 8.6/10 Excellent (1465) "Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina CA $165 CA $252 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/b954d76f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/9df85020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/22a22cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel Berkeley Marina Berkeley 8.2/10 Very good (3642) "Super staff, friendly and gorgeous views of the marina!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Celeste T CA $181 CA $208 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/673f8ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/cb96fe51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/08bea4a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/f5c01e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oakland Marriott City Center Downtown Oakland 9.0/10 Wonderful (1028) "The parking structure is a expensive but kept my car very safe but my stay was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Briana CA $167 CA $194 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Oakland-Hotels-Oakland-Marriott-City-Center.h9019.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/4c4de4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/15f08daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/7d695984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel in San Francisco Downtown San Francisco 8.8/10 Excellent (2717) "Great location clean room super nice staff ☺️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Prakash CA $137 CA $161 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/5e565895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/500/491/fd911583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/1000000/10000/500/491/73838018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/c9a2355d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Downtown SOMA Downtown San Francisco 9.4/10 Exceptional (1299) "Clean hotel in a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $203 CA $295 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/24700/24620/dc12fb50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24700/24620/734c80fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View | Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/24700/24620/9984fcad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/24700/24620/3c00164d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Mark Hopkins by IHG Downtown San Francisco 9.2/10 Wonderful (1164) "Wonderful place, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly Ann CA $178 CA $265 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-Mark-Hopkins.h24620.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/3cb59227.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/a46cfa6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/20278f7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/f38689b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt at SFO San Francisco 9.8/10 Exceptional (1437) "Terrific hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clark CA $405 CA $452 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/San-Francisco-Hotels-Grand-Hyatt-At-SFO.h33462010.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/d2b20643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/b8f68e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/65cb564d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental San Francisco by IHG Downtown San Francisco 9.2/10 Wonderful (1008) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather CA $217 CA $313 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) ![Room (Private Apartment)](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7626c0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7c771a5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/c731c06a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Private Apartment)](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/174738f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clift Royal Sonesta San Francisco Union Square 9.2/10 Wonderful (1336) "Loved my stay here! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Naomi CA $237 CA $333 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/21cb8d87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/c72c1799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/536e3a8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/e6503d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zoe Fisherman's Wharf Fisherman's Wharf 9.2/10 Wonderful (1545) "Staff was very friendly. Rooms were well appointed and beds were very comfortable." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Amy Elizabeth CA $158 CA $246 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) ![Breakfast served, American cuisine](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7b6b8635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/8d3345b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/bd21a30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/85c9e6e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Francisco Airport Bayfront Burlingame 8.6/10 Excellent (2629) "Good location and great service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $137 CA $155 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/74bf4ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/c107a1f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed with Sofa bed | Living room](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/a9e1104a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/51c31a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Francisco Airport Millbrae 8.8/10 Excellent (2056) "Easy to stay here, great staff, always helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald CA $167 CA $234 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/500/487/fda694f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/10000/500/487/ffe8e817.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/10000/500/487/5a346272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/500/487/111baa3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton San Francisco South Airport Blvd South San Francisco 8.4/10 Very good (1973) "Loved the bar! And all staff were wonderful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter CA $166 CA $195 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-South-Airport-Blvd.h487.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/99dd32f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/527c103d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/af41aba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/039db41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin St. Francis San Francisco on Union Square Union Square 8.8/10 Excellent (2440) "Staff were excellent!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sarah CA $237 CA $337 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-St-Francis-San-Francisco-On-Union-Square.h26760.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/c37460ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/3fd8b468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Caza Fisherman's Wharf Fisherman's Wharf 9.0/10 Wonderful (3829) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $165 CA $258 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15300/15254/c499b2e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15300/15254/cc8616ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15300/15254/7caaf63b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/15300/15254/90a739f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beacon Grand, A Union Square Hotel Union Square 9.2/10 Wonderful (1775) "One of the best hotels I’ve stayed at" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trenton CA $225 CA $322 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/San-Francisco-Hotels-Sir-Francis-Drake-Hotel.h15254.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/39d3931a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/49fa748f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/7158d83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/2d47f36f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Argonaut Hotel Fisherman's Wharf 9.4/10 Exceptional (1179) "The hotel was perfect, great location, clean and in a spot that was easy to get around Frisco! " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Catherine CA $276 CA $384 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Downtown-South-San-Francisco-San-Francisco-Hotels.s40-n553248635976481411-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Downtown-South-San-Francisco-San-Francisco-Hotels.s40-n553248635976481411-0.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Downtown South San Francisco. ![Claremont Resort & Club](https://images.trvl-media.com/lodging/1000000/10000/6700/6609/d997dca7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Claremont Resort & Club 41 Tunnel Road, Berkeley, CA CA $390 CA $533 total Nov 9 - Nov 10 includes taxes & fees 8.6/10 Excellent! (1,045 reviews) [](https://expedia.ca/Oakland-Hotels-Claremont-Club-Spa-A-Fairmont-Hotel.h6609.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairmont San Francisco 950 Mason Street Atop Nob Hill, San Francisco, CA CA $322 CA $436 total Nov 23 - Nov 24 includes taxes & fees 9/10 Wonderful! (1,390 reviews) [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![Taj Campton Place](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d044cc49_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Taj Campton Place 340 Stockton St, San Francisco, CA CA $237 CA $327 total Nov 22 - Nov 23 includes taxes & fees 9/10 Wonderful! (1,006 reviews) [](https://expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Still don't see what you're looking for? [See all properties in Downtown South San Francisco.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976481411&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976481411&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976481411&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976481411&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976481411&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F11%2F2025&endDate=04%2F11%2F2025®ionId=553248635976481411&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Downtown South San Francisco Hotel Reviews ![citizenM San Francisco Union Square](//images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/755268ee_y.jpg) ### citizenM San Francisco Union Square 10/10 Excellent "I stayed at many, many hotels but this one beats “old school” traditional chain ones. Absolutely amazing- trendy, artsy, chill; amazing staff, clean, great breakfast and great location! I will definitely stay at the same hotel if coming back to SF. " [](https://expedia.ca/San-Francisco-Hotels-CitizenM-San-Francisco-Union-Square.h69551553.Hotel-Information) ![DoubleTree by Hilton Hotel Berkeley Marina](//images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "Perfect " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](//images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Everything was nice, clean, and price friendly." [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Hotel Caza Fisherman's Wharf](//images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/0bf5bd4c_y.jpg) ### Hotel Caza Fisherman's Wharf 10/10 Excellent "Centrally located, great restaurants near by. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Club Quarters Hotel in San Francisco](//images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "My usual place to stay when I'm in the city." [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Hilton San Francisco Financial District](//images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Great location and friendly staff!" [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![The Marker Union Square San Francisco](//images.trvl-media.com/lodging/1000000/20000/15800/15769/a6ba3784_y.jpg) ### The Marker Union Square San Francisco 10/10 Excellent "Great spot with a great location. Everyone was very friendly. I was provided dinner recommendations at check in. Room was clean and presentable. Location is walking distance to union square. " [](https://expedia.ca/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) ![Beacon Grand, A Union Square Hotel ](//images.trvl-media.com/lodging/1000000/20000/15300/15254/c499b2e7_y.jpg) ### Beacon Grand, A Union Square Hotel 10/10 Excellent "Great place to stay in Union Square! " [](https://expedia.ca/San-Francisco-Hotels-Sir-Francis-Drake-Hotel.h15254.Hotel-Information) ![Hyatt Regency San Francisco](//images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg) ### Hyatt Regency San Francisco 10/10 Excellent "Me and my boyfriend enjoyed and loved our stay for a weekend getaway. I wanted to recognize "Mucha" on the service desk. Her customer service skills is just superb. She was professional and friendly at the same time. We will be back for sure." 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[All Inclusive Resorts and in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-All-Inclusive-Hotel.0-0-d6773-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Beach-Hotel.0-0-d6773-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Boutique-Hotel.0-0-d6773-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Cheap-Hotels.0-0-d6773-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Couples-Resorts-Hotels.0-0-d6773-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Family-Hotel.0-0-d6773-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Historic-Hotel.0-0-d6773-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotel-With-Early-Check-In.0-0-d6773-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Bar in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Bar.0-0-d6773-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d6773-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Free-Breakfast.0-0-d6773-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Free-Parking.0-0-d6773-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Hot-Tubs.0-0-d6773-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Hotels-With-Kitchenettes.0-0-d6773-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-LGBT-Friendly-Hotel.0-0-d6773-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Luxury-Hotel.0-0-d6773-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Mountain-Hotels.0-0-d6773-tMountainHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Oceanfront-Hotels.0-0-d6773-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Pet-Friendly-Hotel.0-0-d6773-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Shopping-Hotel.0-0-d6773-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Spa-Hotel.0-0-d6773-tSpaHotel.Travel-Guide-Filter-Hotels) - [Winery Hotels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Hotels-Winery-Hotel.0-0-d6773-tWineryHotel.Travel-Guide-Filter-Hotels) - [South San Francisco Hotels](https://www.expedia.ca/South-San-Francisco-Hotels.d6773.Travel-Guide-Hotels) - [Houseboats in South San Francisco](https://www.expedia.ca/South-San-Francisco-Houseboats.d6773-aaHouseboats.Travel-Guide-Accommodation) - [Inns in South San Francisco](https://www.expedia.ca/South-San-Francisco-Inns.d6773-aaInns.Travel-Guide-Accommodation) - [Motels in South San Francisco](https://www.expedia.ca/South-San-Francisco-Motels.d6773-aaMotels.Travel-Guide-Accommodation) - [Resorts in South San Francisco](https://www.expedia.ca/South-San-Francisco-Resort-Hotels.d6773-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in South San Francisco Station](https://www.expedia.ca/South-San-Francisco-Station-Apart-Hotels.d6173603-aaApartHotels.Travel-Guide-Accommodation) - [B&B in South San Francisco Station](https://www.expedia.ca/South-San-Francisco-Station-Bed-And-Breakfast.d6173603-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near South San Francisco Station](https://www.expedia.ca/South-San-Francisco-Station-Hotels.d6173603.Travel-Guide-Hotels) - [Townhomes in South San Francisco](https://www.expedia.ca/South-San-Francisco-Townhomes.d6773-aaTownhomes.Travel-Guide-Accommodation) - [Hotels with Free Airport Shuttle in The East Side](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels-Hotels-With-Free-Airport-Shuttle.0-n553248635976472836-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in The East Side](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels-Hotels-With-Free-Breakfast.0-n553248635976472836-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Romantic Hotels in The East Side](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels-Romantic-Hotel.0-n553248635976472836-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [The East Side Hotels](https://www.expedia.ca/The-East-Side-San-Francisco-Hotels.0-n553248635976472836-0.Travel-Guide-Filter-Hotels) - [Flights to San Francisco](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights) - [Flights to South San Francisco](https://www.expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights) - [Flights from Los Angeles (LAX) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/lax/sfo/los-angeles-to-san-francisco) - [Flights from Edmonton (YEG) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco) - [Flights from Montreal (YUL) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco) - [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco) - [Flights from Calgary (YYC) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco) - [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco) - [Visit Paradise Valley](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811) - [South San Francisco Vacations](https://www.expedia.ca/South-San-Francisco.d6773.Destination-Travel-Guides) - [Visit South San Francisco](https://www.expedia.ca/South-San-Francisco.dx6773) - [Rental cars San Francisco Intl. airport](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide) - [Car rental South San Francisco](https://www.expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide) - [Enterprise Rental Cars in South San Francisco](https://www.expedia.ca/Enterprise-Car-Rentals-In-South-San-Francisco.d6773-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in South San Francisco](https://www.expedia.ca/Hertz-Car-Rentals-In-South-San-Francisco.d6773-c40.Car-Rental-Guide-Suppliers) - [South San Francisco Vacation Rentals](https://www.expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals) - [Things to do in South San Francisco](https://www.expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities) - [Book Hotels in Downtown South San Francisco on Expedia.com](https://www.expedia.com/4Star-Downtown-South-San-Francisco-San-Francisco-Hotels.s40-n553248635976481411-0.Travel-Guide-Filter-Hotels)