Photo by Jessica Richter

Find Spa Hotels in Southeast Missouri, MO from CA $102

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Top Southeast Missouri Spa Hotels

Terrace/patio
Silo Farm Haus- located in the heart of wine country!
10.0 out of 10, Exceptional, (127)
"Such a fun property and experience! It was so neat to see a silo haus! Something I could live in one day! The host made the stay comfortable and welcoming. It was so fun and relaxing."
The price is CA $271
CA $410 total
includes taxes & fees
Jun 4 - Jun 5
Silo Farm Haus- located in the heart of wine country!
Exterior
Log Lodge - Secluded - Private Pool - Game Room - WiFi - 1 Hr South of St.Louis
10.0 out of 10, Exceptional, (11)
"It’s beautiful cabin is located in rural St. Mary’s Missouri, it is beautiful, it has a fantastic Layout, which gives privacy for everyone that is staying there. Gorgeous, pool and scenery. I give it 12 out of 10 stars."
Log Lodge - Secluded - Private Pool - Game Room - WiFi - 1 Hr South of St.Louis
Lake
Relax and enjoy the privacy
9.8 out of 10, Exceptional, (16)
"We had a great stay. The cabin is clean and private. The property is beautiful and hot tub was nice. This was the most relaxing weekend away we’ve had. Would definitely come back again."
The price is CA $70
CA $206 total
includes taxes & fees
Jun 4 - Jun 5
Relax and enjoy the privacy
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, (1006)
"Convenient to good restaurants."
The price is CA $159
CA $182 total
includes taxes & fees
Jun 5 - Jun 6
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1004)
"One of the best places I have stayed in. The front desk was polite and professional and advised us of the free dinner they offer and of the free breakfast the next morning. They upgraded us to a suite which was very nice. The property was safe, clean, and looked new, It was conveniently located off the interstate near many restaurants. We had their dinner: bbq sliders, salad, baked beans, Mac n cheese, and coleslaw. They also had hot dogs and nachos. The next morning, we had their...
The price is CA $153
CA $173 total
includes taxes & fees
Jun 5 - Jun 6
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (961)
"The room was just as expected double bed suit with pullout bed worked great for my family of 5. Food options were grest and taste was good. Even though they were at compacity some nights, the parking lot had plenty of spots available. Dairy queen, a pizza buffet place and a gas station were right next door if you needed anything else."
The price is CA $154
CA $163 total
includes taxes & fees
Jun 2 - Jun 3
Drury Inn & Suites Jackson MO
Lobby
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (788)
"The staff were very friendly."
The price is CA $150
CA $169 total
includes taxes & fees
May 31 - Jun 1
Drury Inn & Suites Cape Girardeau
Lobby
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1008)
"My favorite place t to stay we love it"
The price is CA $129
CA $147 total
includes taxes & fees
Jun 2 - Jun 3
Pear Tree Inn Sikeston
Lobby
Drury Inn & Suites Hayti Caruthersville
3.0 star property
9.4 out of 10, Exceptional, (993)
"The receptionist staff were wonderful! And you can’t beat the free snacks and drinks at Drury every evening!"
The price is CA $166
CA $189 total
includes taxes & fees
Jun 5 - Jun 6
Drury Inn & Suites Hayti Caruthersville
Lobby
Drury Inn & Suites Poplar Bluff
3.0 star property
9.2 out of 10, Wonderful, (708)
"The only thing that I was disappointed with is that I did not get my rewards as a Gold Key Member!"
The price is CA $141
CA $160 total
includes taxes & fees
Jun 2 - Jun 3
Drury Inn & Suites Poplar Bluff
Don't see what you're looking for?
See all available properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Spa Hotels information

 

Spa Hotels in Southeast Missouri

114

Highest price
CA $271
Cheapest price
CA $102
Number of guest reviews
5,821
Total number of hotels in Southeast Missouri
570

 

Recent Reviews in Southeast Missouri
Expedia verified reviews

Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

5/5 Excellent
"Enjoyed our stay! "
A verified traveller stayed at Auburn Place Hotel And Suites
Posted 1 day ago
Auburn Place Hotel And Suites