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Southeast Missouri Vacation Rentals

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Vacation Rentals in Southeast Missouri

Exterior
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
3.5 star property
9.4 out of 10, Exceptional, (126)
"When we walked in the lodge it was spotless. Very homey and clean. The staff was so kind. We will definitely be back."
The price is CA $195
CA $222 total
includes taxes & fees
Jun 9 - Jun 10
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Property grounds
Secluded Ozarks Tiny House cabin in Eminence, MO
10.0 out of 10, Exceptional, (78)
"My husband, young children (6 and 4), and I enjoyed our stay. The cabin was cute and clean. Great place to stay."
Secluded Ozarks Tiny House cabin in Eminence, MO
Fridge, microwave, oven, stovetop
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
10.0 out of 10, Exceptional, (68)
"I love staying here. It is so clean and comfortable. I loved waking up in the morning and having my coffee on the front porch soaking in the beautiful natural world. It far enough away from town to enjoy the quiet but close enough to grab delicious food for meals. I’ll always stay here when visiting Eminence."
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
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Property grounds
RIVER FRONT HOUSE
9.8 out of 10, Exceptional, (22)
"Stayed at the property for the Eclipse and had a fantastic view. Was as advertised and outside of a few minor maintenance things was a fantastic stay and we were very pleased!"
RIVER FRONT HOUSE
Pool
River front property HOT TUB, Kayak, tubing, and fishing
9.6 out of 10, Exceptional, (70)
"A little difficult to find. Other wise great. "
The price is CA $230
CA $375 total
includes taxes & fees
May 30 - May 31
River front property HOT TUB, Kayak, tubing, and fishing
TV, fireplace, video games
Van Buren Vacation Rental < 1 Mi to Big Spring!
Van Buren Vacation Rental < 1 Mi to Big Spring!
Lake
Relax and enjoy the privacy
9.8 out of 10, Exceptional, (16)
"We had a great stay. The cabin is clean and private. The property is beautiful and hot tub was nice. This was the most relaxing weekend away we’ve had. Would definitely come back again."
The price is CA $60
CA $195 total
includes taxes & fees
May 22 - May 23
Relax and enjoy the privacy
Fridge, microwave, oven, stovetop
Ozark seclusion with a fully loaded cozy cabin, creeks, springs ,oh my!!!
9.8 out of 10, Exceptional, (105)
"The cabin was perfect for our weekend getaway. We were able to drive fairly short distances to some great hiking trails. The kitchen was well stocked and were able to prepare breakfast/supper, the BBQ grill and fire pit out front were appreciated! We saw deer and turkeys. The hosts were in contact with us for any need that might come up, but we really didn't need a thing."
Ozark seclusion with a fully loaded cozy cabin, creeks, springs ,oh my!!!
Fridge, microwave, stovetop, coffee/tea maker
Beautiful Modern Loft In Wine Country!
10.0 out of 10, Exceptional, (230)
"Such a quiet peaceful place. It was very clean and did not have that crazy cleaning fee."
The price is CA $202
CA $243 total
includes taxes & fees
May 28 - May 29
Beautiful Modern Loft In Wine Country!
Fridge, microwave, oven, stovetop
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (7)
"Very nice little house and good stay"
The price is CA $163
CA $356 total
includes taxes & fees
May 22 - May 23
Cozy Three bedroom home in Central Farmington
Interior
Downtown historic main street
9.6 out of 10, Exceptional, (161)
"The price it says is not accurate, it says it fits 6 but u are charged 25 for each person on top of price of stay."
The price is CA $163
CA $194 total
includes taxes & fees
May 22 - May 23
Downtown historic main street
Fridge, microwave, oven, stovetop
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is CA $204
CA $332 total
includes taxes & fees
May 29 - May 30
Serenity South -- Gardens, River-Views, and Refreshing Space
Exterior
Deadwood Acres cabin #1
9.8 out of 10, Exceptional, (31)
"The host could not BE any nicer or easy to work with. He let us stay late for the eclipse with no fuss. And mailed back a CPAP machine I accidentally left there. The cabin was exactly the right size for a getaway weekend to view the eclipse. Everything was clean, it is easy to find, bit feels remote. We want to explore the property next time we stay - cannot wait to find the creek! We think this could be our base when we float the Jack’s Fork. Excellent all around!"
Deadwood Acres cabin #1
Fridge, microwave, oven, stovetop
Secluded Ozarks Bunk House Cabin at Old Desperado Ranch
10.0 out of 10, Exceptional, (37)
"Beautiful piece of property to get away from everything! The bunkhouse was nice and cozy. Lisa was amazing. Showed great hospitality and put us right on a herd of wild horses. Also made some great suggestions for things to see. We had a great 2 night stay"
Secluded Ozarks Bunk House Cabin at Old Desperado Ranch
Property grounds
Rustic Lodge for 14 near Current River on private 35 acres
10.0 out of 10, Exceptional, (12)
"Nine of us women cousins thoroughly enjoyed our three night stay. Lodge and grounds are beautiful. Everything we needed was right there. Only suggestion would be to include the pool fee in the daily rate and it be available all day. Thanks for a great time."
The price is CA $612
CA $1,047 total
includes taxes & fees
May 22 - May 23
Rustic Lodge for 14 near Current River on private 35 acres
Exterior
The 1801 House: A beautiful historic home in the Ste Genevieve Historic District
10.0 out of 10, Exceptional, (96)
"Our visit was short and we didn’t get to spend much time in the home and town, came for our grandson’s wedding. But the time we had in the house and town was amazing. Thank you for sharing your home with us. It added to the beautiful occasion we came to the area for ☺️"
The 1801 House: A beautiful historic home in the Ste Genevieve Historic District
Property grounds
Deadwood acres cabin #3
10.0 out of 10, Exceptional, (8)
"We were greatly surprised how cute ot was. We stayed to go kayaking."
Deadwood acres cabin #3
Property grounds
Couples Retreat with hot tub (cabin2)
9.6 out of 10, Exceptional, (13)
"This was an amazing place to see the eclipse. The cabin was nice, simple, quiet, and tucked away into the woods. Would go again!"
The price is CA $60
CA $186 total
includes taxes & fees
May 22 - May 23
Couples Retreat with hot tub (cabin2)
Property grounds
Cozy on Current River
10.0 out of 10, Exceptional, (1)
"This was our first time ever staying in a camper. It was very clean, all appliances, and everything in the bathroom worked well. The mattresses were hard, and in hindsight maybe we should have brought something to put on top. The A/C worked like a dream! We were the only ones at the campground and it was so quiet. There is a very nice fire circle, and the river is close by (be prepared to hike through a couple rock beds. Hosts were very easy to work with and were quick to answer our questions."
Cozy on Current River
Interior
Relax on beautiful Current River in Luxury!
10.0 out of 10, Exceptional, (3)
"The camper was very comfortable for 4 adults. Everything was clean. The camper has 2 private bedrooms. The area is very pretty, the Current River within easy walking distance. Plenty of firewood was provided. Excellent star viewing on clear nights. Big Spring is so beautiful and is very close to this location. An enjoyable 3 days!"
Relax on beautiful Current River in Luxury!
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See all available properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Vacation Rental Travel Info

Other types of properties in Southeast Missouri you may be interested in

BBQ/picnic area
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1001)
"Staff and premises were top knotch.i had family come vist and swim for a bit and they were welcoming to my guest.The manager and staff complimented eachother.very good work= physicaly and socially..room was clean smelled good nothing out of place.. I DIDNT WANT TO LEAVE!! LOL THANK YOU FOLKS FOR A WONDERFUL VACATION NIGHT STAY!! THE BEST "
The price is CA $89
CA $101 total
includes taxes & fees
May 26 - May 27
Auburn Place Hotel And Suites
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.0 out of 10, Good, (1002)
"Quiet, easy access, great bed, clean rooms"
The price is CA $94
CA $106 total
includes taxes & fees
May 27 - May 28
Days Inn and Suites by Wyndham Sikeston
Lobby
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1000)
"We did not like the pillows. They were uncomfortable and did not conform to the shape of a person's head/neck."
The price is CA $89
CA $101 total
includes taxes & fees
Jun 2 - Jun 3
Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Southeast Missouri. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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Expedia verified reviews