Title: Southeast Missouri Vacation Rentals from CA $189: Short-Term Rentals for 2025 | Expedia.ca

 

[Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)

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# Southeast Missouri Vacation Rentals

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## Check prices for these dates

In two weeks

[Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-28&endDate=2025-11-30&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-01-09&endDate=2026-01-11&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Vacation Rentals in Southeast Missouri

![Property grounds](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/283ae672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/8cdda898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/c213727d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/57efafb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Micro house cabin located near Silver Mines Recreation Area.

Fredericktown

10/10

Exceptional

(75)

"We had a wonderful stay with Shirley, definitely would be back again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sofia n.

[](https://www.expedia.ca/Fredericktown-Hotels-Micro-House-Cabin-Located-Near-Silver-Mines-Recreation-Area.h66883194.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/93328db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w507h683x259y0-84bc4b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w525h683x259y0-930fe938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, Hulu, streaming services](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w507h683x259y0-c8068718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "Little Brick House on Main (1865)”

Ste. Genevieve

10/10

Exceptional

(62)

"Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lettitia B.

CA $136

CA $192 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Little-Brick-House.h88996203.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/112000000/111840000/111840000/111839902/40ca9dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, toaster](https://images.trvl-media.com/lodging/112000000/111840000/111840000/111839902/04691676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/112000000/111840000/111840000/111839902/a4c427ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/112000000/111840000/111840000/111839902/0fd58969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Unbeatable convenience in amazing Eminence!

Eminence

10/10

Exceptional

(17)

"This is a great value, a spacious home with everything you need including WONDERFUL AC!!! A must for July in MO"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer H.

[](https://www.expedia.ca/Eminence-Hotels-Unbeatable-Convenience-In-Amazing-Eminence.h111839902.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/17fd79b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/941f57c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/e90509fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/89b52c31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau

9.6/10

Exceptional

(42)

"The process was flawless and the location is close to everything!! We enjoyed our stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jack W.

CA $115

CA $194 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Artistic-Indoor-Swing-2-Blocks-To-Downtown.h71736900.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33660000/33654600/33654566/9eaad79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/34000000/33660000/33654600/33654566/068265e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/34000000/33660000/33654600/33654566/7fcb8ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33660000/33654600/33654566/a4f608a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful, secluded cabin in the hills of the Ozarks.

birch tree

9.8/10

Exceptional

(141)

"This place was perfect. Exactly as advertised, super clean, awesome location. Secluded and private. Affordable. We will 100 percent be staying again. It was a treat!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jack w.

[](https://www.expedia.ca/Birch-Tree-Hotels-Ozark-Seclusion-With-A-Fully-Loaded-Cozy-Cabin.h33654566.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78610000/78602600/78602575/50c6616a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player](https://images.trvl-media.com/lodging/79000000/78610000/78602600/78602575/660a6f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/79000000/78610000/78602600/78602575/618e2ef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/79000000/78610000/78602600/78602575/2a572772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### L-Wood Acres: Peaceful Cabin in Arcadia Valley

Ironton

9.8/10

Exceptional

(48)

"This was the perfect location for our first trip as a family of 4! The house was perfect and close to so many things to do."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin S.

[](https://www.expedia.ca/Ironton-Hotels-L-Wood-Acres-Peaceful-Cabin-In-Arcadia-Valley.h78602575.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/w1525h2000x0y0-3cce06ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/9c2435e1_edited_6d62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/d4816ff1_edited_0721.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/b1b7b87a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Springside Cottage in beautiful Eminence. Great outdoor space - NEW Hot tub!

Eminence

9.2/10

Wonderful

(15)

"Cute & convenient to everything!! & love that we was off by ourselves & not around alot of other houses! Will book again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kirstin W.

[](https://www.expedia.ca/Eminence-Hotels-Springside-Cottage-In-Pleasant-Eminence-Great-Outdoor-Space-Large-Yard.h111491747.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/59000000/58090000/58087700/58087650/717b3c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books, offices](https://images.trvl-media.com/lodging/59000000/58090000/58087700/58087650/c81e1363.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/59000000/58090000/58087700/58087650/7b14bff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/59000000/58090000/58087700/58087650/c5f94d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Haven Little Hidden Gem Sleeps 4

Ste.Genevieve

9.8/10

Exceptional

(51)

"Great host and a cozy place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashlynn P.

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Cozy-Haven-Little-Hidden-Gem-Sleeps-4.h58087650.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1020h683x4y0-fa4cb879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1024h480x0y101-641c723e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, DVD player, books, video library](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1024h455x0y114-14a42b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1014h683x5y0-c3534739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Collier Cabin in Pine Hollow ~ Eminence, MO

Birch Tree

9.6/10

Exceptional

(23)

"Beautiful cabin surrounded with woods, we saw three turtles and made friends with lots of bugs. We were a lot closer to the owners than I thought, but they were very kind people. They were very active on communication as well!! Would recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Savanna L.

[](https://www.expedia.ca/Birch-Tree-Hotels-Collier-Cabin-In-Pine-Hollow-Eminence.h104123411.Hotel-Information)

![1 bedroom, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/86d734a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player, video library](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/17e1434d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/81907571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/08a1bdfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Modern Loft In Wine Country!

Ste. Genevieve

10/10

Exceptional

(270)

"Beautiful loft on beautiful property!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Addison G.

CA $208

CA $253 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Beautiful-Modern-Loft-In-Wine-Country.h23139432.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/94000000/93410000/93401200/93401117/58740108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93410000/93401200/93401117/75ea9880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/94000000/93410000/93401200/93401117/4012ddc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93410000/93401200/93401117/a9526e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Sutton House 2 blocks from Main Street & Courthouse Square

Ironton

10/10

Exceptional

(42)

"Perfect location for all the nearby state parks. Bedrooms are generous sized areas so individuals could have some down-time in their own area if they wished. We loved it and would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angela H.

CA $140

CA $189 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Ironton-Hotels-The-Sutton-House-2-Blocks-From-Main-Street-Courthouse-Square.h93401117.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66200000/66199100/66199066/15c37025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/67000000/66200000/66199100/66199066/8ca8555c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/67000000/66200000/66199100/66199066/1f8cdae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/67000000/66200000/66199100/66199066/7f2cfbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Secluded Ozarks Bunk House Cabin at Old Desperado Ranch

Eminence

10/10

Exceptional

(54)

"Great place for a couple to have a little getaway! It is small, but clean, and the owners are super friendly! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly P.

[](https://www.expedia.ca/Eminence-Hotels-Secluded-Ozarks-Bunk-House-Cabin-At-Old-Desperado-Ranch.h66199066.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119320000/119310900/119310813/c347e331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119320000/119310900/119310813/5cb6ee33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119320000/119310900/119310813/358bd3b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/120000000/119320000/119310900/119310813/1c3a97fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2 bedroom cabin on a beautiful private lake.

Ironton

9.4/10

Exceptional

(16)

"Place is nice & easy to find. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mercy

CA $183

CA $274 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Arcadia-Hotels-Charming-2-Bedroom-Cabin-On-A-Beautiful-Private-Lake.h119310813.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/2fc67c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/b5064413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/93347520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, computer monitors](https://images.trvl-media.com/lodging/74000000/73470000/73470000/73469992/54de2de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin 1 at the Pallet Factory

Leadwood

9.6/10

Exceptional

(35)

"The property offered excellent privacy, making it a perfect retreat. The pond was beautiful, providing a serene spot to float and relax all weekend. Ending our nights in the hot tub was a fantastic experience. Overall, it was a wonderful getaway.""

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sharon C.

CA $50

CA $219 total

includes taxes & fees

Nov 12 - Nov 13

[](https://www.expedia.ca/Park-Hills-Hotels-Relax-And-Enjoy-The-Privacy.h73469992.Hotel-Information)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/701aec9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/f0863f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/b16ce2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/bccf3a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Poplar Bluff

8.6/10

Excellent

(8)

"The house was very clean and nicely decorated. The huge TV in the living room was a plus and the mattress was very comfortable. We would stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian

CA $140

CA $356 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Charming-2-Bedroom-House-With-2-KING-BEDS-In-Pleasant-Poplar-Bluff.h110066526.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/570788ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/04c500be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/eed3215e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/831297c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### #ContemplationCabin on the Jacks Fork River!

Summersville

10/10

Exceptional

(70)

"The location was amazing. The water was beautiful. Very relaxing experience."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary M.

CA $351

CA $475 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Contemplationcabin-On-The-Jacks-Fork-River.h59955709.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/5f66921b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/e25fadd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/0622af9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/2751478e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Secluded Getaway Cabin within minutes of amenities

Cape girardeau

10/10

Exceptional

(17)

"Loved the area . It was quiet and peaceful and not too far from town"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

CINDY K.

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Charming-Getaway-Cabin.h75891457.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/33adbe32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/a0649327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/65f5a89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/0fce9903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Wappapello

Williamsville

10/10

Exceptional

(1)

"We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dyann

CA $194

CA $204 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Williamsville-Hotels-Lake-Wappapello.h114278842.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/36000000/35680000/35673000/35672916/d6d17598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/36000000/35680000/35673000/35672916/88aca2ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/36000000/35680000/35673000/35672916/10d16db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/36000000/35680000/35673000/35672916/32c7e2af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Secluded Ozarks Tiny House cabin in Eminence, MO

Eminence

9.6/10

Exceptional

(102)

"Beautiful, secluded tiny house tucked into the Ozark hills on a working horse ranch. We were lucky to be there when a large trail ride was passing through and got to watch riders come by all day. Very helpful hosts gave us our space but were available to assist with anything if needed. Bonus: ice cream was awesome!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

rebecca i.

[](https://www.expedia.ca/Eminence-Hotels-Secluded-Ozarks-Tiny-House-Cabin-In-Eminence.h35672916.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/e186477c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/1422cf76_edited_0171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/298cfcd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/107000000/106060000/106052600/106052541/52de7a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

Ste. Genevieve

10/10

Exceptional

(14)

"Awesome from checking in to all of the place was excellent!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michelle A.

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Rivertown-Retreat-Historic-Dufour-House-Circa-1800Downtown-District-Sleeps-4.h106052541.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Southeast Missouri Hotel Reviews

![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg)

### Tru By Hilton Cape Girardeau

10/10 Excellent

"Amaiah at the front desk was amazing! She Answered all my questions and double checked that our room was ready since I was a15 minutes early."

[](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Everyone was friendly and polite. Great stay and staff….."

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg)

### Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Clean and friendly staff!!!"

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![The Farmstead Hotel](//images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg)

### The Farmstead Hotel

10/10 Excellent

"Clean room and staff was very helpful "

[](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"Nice accomodations "

[](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg)

### Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent

"Ok"

[](https://expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![Fairfield Inn & Suites by Marriott Poplar Bluff](//images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg)

### Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent

"The room has been intentionally created to be comfortable and pleasing to the eye. There are night stands on both sides of the bed. Every part of the room, from the generous sized shower with secure shelf for your own toiletries, a hook for the towel, and plenty of space to enter and exit, to the attractive and useful placement of the “kitchen” area, with lots of extra electrical outlets in case you bring a small crockpot, etc., to the ergonomic desk area with good space for a computer. When we arrived last night, I was only aware of the pleasant attendant at the desk and the need for the comfortable king sized bed, but this morning, I’m really appreciating all the care put into designing this room. "

[](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"The room was clean and comfy. The staf was friendly, courteous and efficient. Many thanks!"

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Room was clean and check in was quick and efficient."

[](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

## Find out more about Southeast Missouri

**Everything you need to know about** **Southeast Missouri** **vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southeast Missouri vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southeast Missouri vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Southeast Missouri vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Southeast Missouri. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Southeast Missouri vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Southeast Missouri vacation rentals we have selected for you start as low as CA $189 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Southeast Missouri rentals**

At Expedia, we put the best Southeast Missouri vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Southeast Missouri rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southeast Missouri vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southeast Missouri. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

## Explore a world of travel with Expedia

-   Trending destinations on Expedia.ca
-   All accommodation types in Southeast Missouri

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-   [British Columbia Vacation Rentals](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations)
-   [Prince Edward Island Vacation Rentals](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations)
-   [Québec Vacation Rentals](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

-   [Vacation Homes in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Private-Vacation-Homes.d6058763-aaPrivateVacationHomes.Travel-Guide-Accommodation)
-   [Cabin Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Cabins.d6058763-aaCabins.Travel-Guide-Accommodation)
-   [Cottages in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Cottages.d6058763-aaCottages.Travel-Guide-Accommodation)
-   [Apartments in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Apartments.d6058763-aaApartments.Travel-Guide-Accommodation)
-   [Motels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Motels.d6058763-aaMotels.Travel-Guide-Accommodation)
-   [Farmstay in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Agritourism.d6058763-aaAgritourism.Travel-Guide-Accommodation)
-   [RV Parks in Southeast Missouri](https://expedia.ca/Southeast-Missouri-RV-Parks.d6058763-aaRVParks.Travel-Guide-Accommodation)
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-   [Aparthotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Apart-Hotels.d6058763-aaApartHotels.Travel-Guide-Accommodation)
-   [B&B in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Bed-And-Breakfast.d6058763-aaBedAndBreakfast.Travel-Guide-Accommodation)
-   [Villas in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Villas.d6058763-aaVillas.Travel-Guide-Accommodation)
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Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app

![QR code to download the app](data:image/png;base64,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)