Title: Book The Best Hotels in Southeast Missouri, MO for 2025 from CA $85 - Fully Refundable Options - Expedia.ca

 

[Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)

![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:
Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.
It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.
This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 
#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Bill Dillard

# Find hotels in Southeast Missouri, MO from CA $85

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## Go beyond your typical stay in Southeast Missouri

Farm

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&lodging=AGRITOURISM)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=WATER_PARK)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&travelerType=family_friendly)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&lodging=CABIN)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&lodging=COTTAGE)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&lodging=APARTMENT)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=HOT_TUB)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=POOL)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2025-12-05&d1=2025-12-05&endDate=2025-12-07&d2=2025-12-07&amenities=PETS)

## Check prices for these dates

Tonight

[Nov 21 - Nov 22](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 22 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-22&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 613 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/060976ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/35f08a54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/13275a81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Farmstead Hotel

Caruthersville

8.8/10

Excellent

(449)

"Clean rooms and really comfortable beds!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrea

CA $114

CA $130 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Perryville by IHG

Perryville

9.2/10

Wonderful

(532)

"Clean room and pleasant staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $134

CA $154 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1008)

"This was a wonderful stay. We will definitely stay again when we are in town!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Trista

CA $117

CA $124 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

Cape Girardeau

9.0/10

Wonderful

(1002)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Heather

CA $99

CA $111 total

includes taxes & fees

Nov 27 - Nov 28

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d234bb55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/e565804d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/5d1ea140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/3a2c35d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Farmington

Farmington

8.0/10

Very good

(602)

"Clean, friendly staff, quiet"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stacy

CA $78

CA $89 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information)

![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/2cf60fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/b3da6b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/79923507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/158800/158717/05c7ee11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Potosi

Potosi

7.0/10

Good

(375)

"The room was very good for the price."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Benjamin

CA $78

CA $85 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Potosi.h158717.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/db5aadc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/0c1d1e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's play area - outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Echo Bluff State Park

Eminence

9.6/10

Exceptional

(215)

"Beautiful location…excellent service and facilities / grounds were clean and well kept."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $202

CA $214 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/7e9b49ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Building design](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/f4d876e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/c41116cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

8.0/10

Very good

(1000)

"The room was clean and the staff, as always were very courteous!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steven

CA $77

CA $87 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1001)

"Very nice stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charity

CA $127

CA $143 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/b4e45ee9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/a5281c8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/49c875c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Hayti Caruthersville

Hayti

9.4/10

Exceptional

(1003)

"Great stay. Clean room, and Drury Inns always seem to have the most comfortable beds."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ted

CA $132

CA $151 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information)

![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

Cape Girardeau

9.4/10

Exceptional

(1002)

"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sandra

CA $127

CA $143 total

includes taxes & fees

Nov 25 - Nov 26

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/219ce8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/e3f5b676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/6e9d01e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/b5436bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Festus

Festus

6.8/10

(914)

"Staff was great, room was tidy"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Victoria

CA $108

CA $123 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(653)

"Stayed on our way south for vacation. It was a clean nice place to stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joel

CA $119

CA $128 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1001)

"Nice place for a stay at a reasonable price."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Arthur

CA $99

CA $111 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/874a4e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/59050052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/0a692e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Poplar Bluff by IHG

Poplar Bluff

8.8/10

Excellent

(690)

"Amazing place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mladen

CA $140

CA $158 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/720261dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/2d71c942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/w7137h4758x0y0-7ae60078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/6d872386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

9.4/10

Exceptional

(695)

"Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy

CA $157

CA $179 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/7f26b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Perryville

Perryville

8.4/10

Very good

(931)

"We stayed one night. It was fine. Wouldn’t stay here for an extended time. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Randy

CA $92

CA $106 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

9.0/10

Wonderful

(426)

"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Doncheial

CA $134

CA $152 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/363ef183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Riverview Two Queen Room](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Riverview

Cape Girardeau

9.4/10

Exceptional

(457)

"Place was nice and safe"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ryan

CA $133

CA $151 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-06&endDate=2025-12-07&regionId=6058763&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:**Dec 5 - Dec 7**

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Echo Bluff State Park

Eminence

**9.6/10**Exceptional (215 reviews)

5% off

CA $253

CA $536 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=15487684&adults=2)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Hampton Inn Poplar Bluff

Poplar Bluff

**9.4/10**Exceptional (789 reviews)

20% off

CA $149

CA $335 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=9827793&adults=2)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Hampton Inn Sikeston

Sikeston

**9.0/10**Wonderful (426 reviews)

20% off

CA $146

CA $330 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=25178175&adults=2)

![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Tru By Hilton Cape Girardeau

Cape Girardeau

**9.6/10**Exceptional (94 reviews)

20% off

CA $146

CA $331 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=111590879&adults=2)

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83530000/83521000/83520985/c366c0a2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Private scenic Ozark Mountain retreat near beautiful Current River; sleeps 1-10!

Van Buren

**10/10**Exceptional (22 reviews)

5% off

CA $569

CA $1,624 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=83520985&adults=2)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Riverview

Cape Girardeau

**9.4/10**Exceptional (457 reviews)

10% off

CA $326

CA $736 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=105081384&adults=2)

![Children's play area - outdoor](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/e8909449.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Honeysuckle Inn - Mountain View

Mountain View

**8.6/10**Excellent (329 reviews)

15% off

CA $145

CA $314 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=42093410&adults=2)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/81000000/80810000/80805700/80805648/f332399a.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Private Hilltop Cabin Near Current River

Van Buren

**10/10**Exceptional (60 reviews)

5% off

CA $240

CA $661 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=80805648&adults=2)

![Interior](https://images.trvl-media.com/lodging/83000000/82930000/82926400/82926341/371f868e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Lake Road Cabin B — Million Dollar Ozark View!

Ironton

**10/10**Exceptional (23 reviews)

5% off

CA $214

CA $589 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=82926341&adults=2)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/85b01dbf.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Mountain View at Pickle & Perk

Ironton

**10/10**Exceptional (14 reviews)

5% off

CA $213

CA $557 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=105789927&adults=2)

![Private kitchen](https://images.trvl-media.com/lodging/71000000/70560000/70553000/70552948/0be52867.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Bluebird Meadows W/hot Tub and Pool Special

Park Hills

**10/10**Exceptional (2 reviews)

5% off

CA $548

CA $1,348 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=70552948&adults=2)

![Exterior](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/3eea0c0d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Hampton Inn Farmington

Farmington

**8.8/10**Excellent (515 reviews)

20% off

CA $196

CA $446 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=3594547&adults=2)

![Standard Room, 1 Queen Bed, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Rockwood Inn

Cape Girardeau

**10/10**Exceptional (17 reviews)

12% off

CA $247

CA $558 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=105486893&adults=2)

![Exterior](https://images.trvl-media.com/lodging/72000000/71730000/71720200/71720165/14e44f48.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Deadwood Acres cabin #2

Eminence

**9.8/10**Exceptional (37 reviews)

5% off

CA $186

CA $475 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=71720165&adults=2)

![Lobby](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/83119f36.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Crown Pointe Lodge, BW Signature Collection

Farmington

**9.0/10**Wonderful (568 reviews)

20% off

CA $147

CA $334 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=1429479&adults=2)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91470000/91463000/91462996/b04eceb5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Black River Retreat 5 Minutes from Jeff’s Canoe Rental /K Bridge

Redford

**10/10**Exceptional (15 reviews)

5% off

CA $368

CA $1,033 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=91462996&adults=2)

![Exterior](https://images.trvl-media.com/lodging/94000000/93410000/93401200/93401117/58740108.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Sutton House 2 blocks from Main Street & Courthouse Square

Ironton

**10/10**Exceptional (44 reviews)

5% off

CA $206

CA $534 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=93401117&adults=2)

![Shared kitchen](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/66a0aee5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Arcadia Academy

Arcadia

**9.8/10**Exceptional (11 reviews)

17% off

CA $159

CA $346 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=112360980&adults=2)

![Outdoor dining](https://images.trvl-media.com/lodging/28000000/27120000/27117600/27117570/7f62725f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### 🔝❤️ PEACEFUL TREETOP COTTAGE

Park Hills

**10/10**Exceptional (50 reviews)

5% off

CA $317

CA $804 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=27117570&adults=2)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68130000/68128800/68128717/a4fdad32.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Five minute walk to middle fork Black River, 7 miles to Johnson Shut ins.

Lesterville

**9.8/10**Exceptional (27 reviews)

5% off

CA $268

CA $715 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=68128717&adults=2)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117060000/117059500/117059459/2c551ba9.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The King Suite at Pickle & Perk

Ironton

**10/10**Exceptional (2 reviews)

5% off

CA $200

CA $492 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=117059459&adults=2)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83010000/83001100/83001017/51aa3e66_edited_97d9.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Jacks Fork Town House in Eminence

Eminence

**9.6/10**Exceptional (18 reviews)

5% off

CA $255

CA $624 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=83001017&adults=2)

![Terrace/patio](https://images.trvl-media.com/lodging/48000000/47020000/47014500/47014463/d24d09c9.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### CLEAR VIEW CABIN - only 1 mile from Van Buren & Current Rvr @ Big Spring Park!

Van Buren

**9.8/10**Exceptional (84 reviews)

5% off

CA $668

CA $2,027 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=47014463&adults=2)

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Farmstead Hotel

Caruthersville

**8.8/10**Excellent (449 reviews)

10% off

CA $121

CA $274 total

includes taxes & fees

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-05&endDate=2025-12-07&selected=89303450&adults=2)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

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## 

Black Friday Sale

Limited-time deals: save up to 50% on select hotels

[Book now](https://expedia.ca/deals?rfrr=HTG_BF_PROMO_6058763)

## Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to Walnut Hollow Lake.

[See all hotels in Southeast Missouri](https://www.expedia.ca/Hotel-Search?startDate=2025-12-06&endDate=2025-12-07&adults=2&regionId=6058763)

![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:
Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.
It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.
This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 
#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=899&h=600&p=1&q=high)

Photo by Bill Dillard

### Stay near popular Southeast Missouri attractions

[](https://expedia.ca/Elephant-Rocks-State-Park-Hotels.0-l553248621532648464-0.Travel-Guide-Filter-Hotels)

![Elephant Rocks State Park](https://mediaim.expedia.com/destination/2/86e50eabc9d5592586815e7688be64ef.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648464)

[](https://expedia.ca/Lake-Wappapello-Hotels.0-l553248621532648460-0.Travel-Guide-Filter-Hotels)

![Lake Wappapello](https://mediaim.expedia.com/destination/2/a6135d9f1717ada26d9944dd5bb40459.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648460)

[](https://expedia.ca/Rocky-Falls-Hotels.0-l553248621532648456-0.Travel-Guide-Filter-Hotels)

![Rocky Falls](https://mediaim.expedia.com/destination/2/f2325d7f040c776e314b23ad9fbdb813.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Rocky Falls

Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648456)

[](https://expedia.ca/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels)

#### Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621554122994)

[](https://expedia.ca/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels)

#### Century Casino Caruthersville

Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532655201)

[](https://expedia.ca/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels)

#### Isle Casino Cape Girardeau

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532655780)

## More cheap stays in Southeast Missouri

![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

CA $77

CA $87 total

Nov 30 - Dec 1

includes taxes & fees

8/10 Very Good! (1,000 reviews)

[](https://expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

CA $107

CA $113 total

Nov 24 - Nov 25

includes taxes & fees

7.8/10 Good! (1,000 reviews)

[](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

CA $89

CA $101 total

Nov 23 - Nov 24

includes taxes & fees

7.2/10 Good! (1,000 reviews)

[](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

CA $99

CA $111 total

Nov 27 - Nov 28

includes taxes & fees

9/10 Wonderful! (1,000 reviews)

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

CA $129

CA $145 total

Nov 30 - Dec 1

includes taxes & fees

9.4/10 Exceptional! (1,000 reviews)

[](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Fairfield Inn & Suites by Marriott Poplar Bluff](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove Poplar Bluff MO

CA $147

CA $166 total

Nov 24 - Nov 25

includes taxes & fees

9.4/10 Exceptional! (839 reviews)

[](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

## Hotels in Southeast Missouri with star-rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg)

4 Star Hotels

1 properties

[](https://expedia.ca/4Star-Southeast-Missouri-Hotels.s40-0-d6058763.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

53 properties

[](https://expedia.ca/3Star-Southeast-Missouri-Hotels.s30-0-d6058763.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

124 properties

[](https://expedia.ca/2Star-Southeast-Missouri-Hotels.s20-0-d6058763.Travel-Guide-Filter-Hotels)

## Recent reviews of Southeast Missouri hotels

![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

5/5 Excellent

"Great room, close to downtown, awesome food options in the venue as well. Really nice views of the river."

A verified traveller stayed at The Riverview

Posted 3 days ago

[](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Holiday Inn Poplar Bluff by IHG](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7_y.jpg)

### Holiday Inn Poplar Bluff by IHG

5/5 Excellent

"Very spacious suite, awesome staff! "

A verified traveller stayed at Holiday Inn Poplar Bluff by IHG

Posted 3 days ago

[](https://expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

5/5 Excellent

"This was a really great stay, which was part of my long roadtrip. The hotel was right off the interstate & wasn't too noisy. My room was pretty big which I really enjoyed! The bed was super comfy. The front desk woman was super friendly and welcoming. I was able to get Door Dash to deliver to the location so that was a plus! They had quite a lot of items for breakfast, so I was surprised about that for a Days Inn. Only thing I didn't like was lack of parking, but overall, I would definitely stay here again if I come back to the area."

A verified traveller stayed at Days Inn and Suites by Wyndham Sikeston

Posted 3 days ago

[](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

5/5 Excellent

"The room was very clean. We received great service. "

A verified traveller stayed at Drury Inn & Suites Jackson MO

Posted 4 days ago

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

5/5 Excellent

"Clean and good service "

A verified traveller stayed at Pear Tree Inn Cape Girardeau West

Posted 4 days ago

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg)

### Hampton Inn Sikeston

5/5 Excellent

"The place was nice and clean"

A verified traveller stayed at Hampton Inn Sikeston

Posted 4 days ago

[](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

5/5 Excellent

"Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks. "

A verified traveller stayed at Drury Inn & Suites Sikeston, MO

Posted 4 days ago

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg)

### The Farmstead Hotel

5/5 Excellent

"Clean room! Very friendly and helpful staff, especially the lady from Blytheville that helped us check in the first night. Only complaint is that in the middle of the day, the lobby filled up with cigarette smoke because the back door was left open during smoke break. "

A verified traveller stayed at The Farmstead Hotel

Posted 4 days ago

[](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

5/5 Excellent

"Clean rooms. Very comfortable bed. Friendly staff "

A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center

Posted 4 days ago

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

## Frequently asked questions

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Southeast Missouri hotel for you.

### How can I save on a Southeast Missouri hotel booking with Expedia?

> Members always get our best prices. Find our best Southeast Missouri hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Southeast Missouri hotel?

> Prices for hotels in Southeast Missouri often vary, but you can find a great deal from CA $85 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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-   [Avis Rental Cars in Farmington](https://www.expedia.ca/Avis-Car-Rentals-In-Farmington.d6058764-c41.Car-Rental-Guide-Suppliers)
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-   [National Car Rental Rental Cars in Fredericktown](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Fredericktown.d55114-c42.Car-Rental-Guide-Suppliers)

-   [Marble Hill Vacation Rentals](https://www.expedia.ca/Marble-Hill-Vacation-Rentals.d3000445212.Travel-Guide-VacationRentals)

-   [Book Hotels in Southeast Missouri on Expedia.com](https://www.expedia.com/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)

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