Southeast Missouri
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is CA $144 per night from Aug 24 to Aug 25
CA $144
CA $162 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,006 reviews)
"Excellent place to stay 3 free drinks during happy and good supper and breakfast. Will stay in a Drury Inn whenever one is available."
Reviewed on Jul 27, 2026
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is CA $85 per night from Aug 11 to Aug 12
CA $85
CA $92 total
Aug 11 - Aug 12
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
The Riverview
777 Main St Cape Girardeau MO
The price is CA $144 per night from Aug 3 to Aug 4
CA $144
CA $162 total
Aug 3 - Aug 4
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
9.4/10 Exceptional! (635 reviews)
"Very clean property all the way around!"
Reviewed on Jul 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
Stay at this country house in Ste Genevieve. Enjoy laundry facilities. Popular attractions Crown Valley Winery and Hawn State Park are located nearby.
10/10 Exceptional! (154 reviews)
"Our stay at the Silo House was absolutely wonderful! The home and surrounding property are stunning, and the peaceful setting made it the perfect escape from the hustle and bustle of everyday life. If you’re looking for a place to truly relax and recharge, this is it.My favorite part of the entire ..."
Reviewed on Jul 5, 2026
Lake Wappapello
8005 Missouri 172 Williamsville MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
8.8/10 Excellent! (3 reviews)
"I had a reservation for 4 nights, also received a confermation and itinerary number from hotes.com, but upon arrival I found that hotels.cim never made the reservation with the place I was staying. The place i was supposed to stay at were as accommodating as they could be, tried to find me a place ..."
Reviewed on Jun 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Southeast Missouri hotel availability
Stay near popular Southeast Missouri attractions
Things to do
Night Ghost Tour of Pythian Castle in Springfield Missouri
CA $28
per adult
100% of travellers recommend
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- Postcard Cabins St Francois
- Farmstay in Oak Ridge
- Poplar Bluff Hotels
- Hampton Inn Poplar Bluff
- Spring Lake Ranch has a Private
- Crown Pointe Lodge
- Bullwinkles Rustic Lodge
- Holiday Inn Poplar Bluff by IHG
- Resorts in Wayne County
- Town House Inn
- Advance Hotels
- Super 8 by Wyndham Perryville
- Houseboats in Wappapello
- Villas in Poplar Bluff
- Cabin Rentals in Southeast Missouri
- Park Hills Hotels
- Cozy Caledonia Cabin ~ 10 Mi to Elephant Rocks!
- Bluebird Meadows W/hot Tub and Pool Special
- Motels in St Mary
- The Weber Farm
- French Village Hotels
- Cabin Rentals in Bonne Terre
- Motels in Ellsinore
- Home Sweet Home
- Cottages in Clearwater
- Hilton Hotels in Ste Genevieve
- Cabin Rentals in Centerville
- Pickleball Cafe & Micro Hotel
- Dexter Inn
- Quality Inn Perryville I
- Cheap Hotels in Bonne Terre
- B&B in Ste Genevieve
- Rv Parks in Perryville
- Rv Parks in Chaffee
- Amazing lakeview Spring Lake Tree House #2 "LoveLight" w/ hot tub
- Hotels near Big River
- Lazy River Cabin on the edge of town only 1/2 mile from Current River !
- The Queen Bee Farm Stay/Hot tub
- Essex Hotels
- Pine Perfect Cabin on the edge of town only 1/2 mile from Current River!
- Secluded Private Cabin with Pool
- Silo Farm Haus
- Cheap Hotels in Viburnum
- Relax in the country at Countryside Villas!
- Secluded Cabin with Heated Pool
- Hilton Hotels in Perryville
- Cabin Rentals in Allenville
- Jackson Hotels
- Apartments in Ozora
- Bonne Terre Hotels
- Cabin Rentals in Farmington
- Urban Loft #4 BLACK · Urban Loft above BrewCo & Restaurant
- Triangle Inn Motel
- Condo Rentals in Fremont
- Cabin Rentals in Cadet
- Dexter Hotels
- Cabin Rentals in Leadwood
- Ozora Hotels
- Pet-Friendly Hotels in Jackson
- Fredericktown Hotels
- Cottages in Pocahontas
- Van Buren Hotels
- Alpaca Farm Stay
- Oyo Hickory House Inn
- Flights from Bonne Terre
- Flights from Los Angeles (LAX) to Poplar Bluff (POF)
- Flights from Arcadia
- Flights to Dexter
- Flights from Edmonton (YEG) to Cape Girardeau (CGI)
- Flights to Farmington
- Flights from Ocala (OCF) to Cape Girardeau (CGI)
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- Flights from Eugene (EUG) to Cape Girardeau (CGI)
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- Flights from Belleview
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- Flights to Butler County
- Flights from Montreal (YUL) to Cape Girardeau (CGI)
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- Flights from Colombo (CMB) to Cape Girardeau (CGI)
- Flights to Bonne Terre
- Flights from Grand Island (GRI) to Cape Girardeau (CGI)
- Flights from St. Louis (STL) to Poplar Bluff (POF)
- Flights from Toronto (YTO) to Cape Girardeau (CGI)
- Flights from Chaffee
