A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

South San Diego Vacation Rentals

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Our top choices for South San Diego vacation rentals

1. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,214 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is CA $215
CA $249 total
includes taxes & fees
Sep 30 - Oct 1
Marriott Vacation Club®, San Diego

2. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (317 reviews)
"great stay"
United States
alex
The price is CA $138
CA $160 total
includes taxes & fees
Oct 14 - Oct 15
Little Italy Inn - Limited Service Apart Hotel

3. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (472 reviews)
"It's good hotel for small day 1 to 3 nights no more then that due to the size of the room."
Canada
patrick
The price is CA $132
CA $149 total
includes taxes & fees
Oct 26 - Oct 27
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

4. Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (822 reviews)
"The staff was wonderful and they had get togethers in the lobby and activities!"
United States
Phyllis
The price is CA $292
CA $321 total
includes taxes & fees
Oct 25 - Oct 26
Coronado Beach Resort

5. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (210 reviews)
"Receptionist was super nice and super helpful. The location was perfect. Everything was super close. Loved the room."
United States
Victor
The price is CA $165
CA $234 total
includes taxes & fees
Oct 26 - Oct 27
City24 Hotel Little Italy Mission Hills

6. Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
3.0 star property
Windsor Hills
The price is CA $731
CA $1,328 total
includes taxes & fees
Oct 2 - Oct 3
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck

7. 2BR Condo Steps to the Beach & Blvd-dog-friendly

2BR Condo Steps to the Beach & Blvd-dog-friendly
3.0 star property
Mission Beach
The price is CA $427
CA $968 total
includes taxes & fees
Sep 27 - Sep 28
2BR Condo Steps to the Beach & Blvd-dog-friendly

8. < 2 Mi to Pacific Beach! Sunny San Diego Escape

< 2 Mi to Pacific Beach! Sunny San Diego Escape
3.0 star property
Pacific Beach
7.4 out of 10, Good, (3 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
The price is CA $495
CA $1,093 total
includes taxes & fees
Sep 27 - Sep 28
< 2 Mi to Pacific Beach! Sunny San Diego Escape
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South San Diego Hotel Reviews

Find out more about South San Diego

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with South San Diego. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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