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CA $222 Cheap Flights from Buffalo (BUF) to San Diego (SAN)

View CA $222 flight on Sat, Sep 5, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)

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Cheap flights from Buffalo (BUF) to San Diego (SAN)

Prices were available within the past 7 days and start at CA $222 for one-way flights and CA $443 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Sep 5 - Sat, Sep 12
BUF
Buffalo
SAN
San Diego
CA $443 Roundtrip, found 3 days ago
CA $443
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 5 from Buffalo to San Diego, returning Sat, Sep 12, priced at CA $443 found 3 days ago
American Airlines
Sat, Sep 5 - Sat, Sep 12
BUF
Buffalo
SAN
San Diego
CA $444 Roundtrip, found 3 days ago
CA $444
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Sep 5 from Buffalo to San Diego, returning Sat, Sep 12, priced at CA $444 found 3 days ago
Delta
Sat, Sep 5 - Sun, Sep 13
BUF
Buffalo
SAN
San Diego
CA $450 Roundtrip, found 3 days ago
CA $450
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 5 from Buffalo to San Diego, returning Sun, Sep 13, priced at CA $450 found 3 days ago
American Airlines
Fri, Sep 11 - Sun, Sep 13
BUF
Buffalo
SAN
San Diego
CA $451 Roundtrip, found 3 days ago
CA $451
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Sep 11 from Buffalo to San Diego, returning Sun, Sep 13, priced at CA $451 found 3 days ago
Delta
Fri, Oct 30 - Sun, Nov 15
BUF
Buffalo
SAN
San Diego
CA $456 Roundtrip, found 10 hours ago
CA $456
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Oct 30 from Buffalo to San Diego, returning Sun, Nov 15, priced at CA $456 found 10 hours ago
American Airlines
Tue, Nov 3 - Sun, Nov 8
BUF
Buffalo
SAN
San Diego
CA $458 Roundtrip, found 4 days ago
CA $458
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Nov 3 from Buffalo to San Diego, returning Sun, Nov 8, priced at CA $458 found 4 days ago
Delta
Thu, Dec 24 - Mon, Jan 4
BUF
Buffalo
SAN
San Diego
CA $459 Roundtrip, found 3 hours ago
CA $459
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Dec 24 from Buffalo to San Diego, returning Mon, Jan 4, priced at CA $459 found 3 hours ago
JetBlue Airways
Mon, Aug 31 - Sat, Sep 5
BUF
Buffalo
SAN
San Diego
CA $522 Roundtrip, found 3 days ago
CA $522
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Mon, Aug 31 from Buffalo to San Diego, returning Sat, Sep 5, priced at CA $522 found 3 days ago
United
Sat, Sep 5 - Sat, Sep 12
BUF
Buffalo
SAN
San Diego
CA $598 Roundtrip, found 3 days ago
CA $598
Roundtrip
found 3 days ago
Select United flight, departing Sat, Sep 5 from Buffalo to San Diego, returning Sat, Sep 12, priced at CA $598 found 3 days ago
Alaska Airlines
Tue, Dec 22 - Fri, Jan 1
BUF
Buffalo
SAN
San Diego
CA $838 Roundtrip, found 3 hours ago
CA $838
Roundtrip
found 3 hours ago
Select Alaska Airlines flight, departing Tue, Dec 22 from Buffalo to San Diego, returning Fri, Jan 1, priced at CA $838 found 3 hours ago

Alternative airports near San Diego

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McClellan-Palomar CLD. Average driving time to city centre is 38 minutes. Flights from CA $884
CLD
McClellan-Palomar
Average driving time to city centre38 min
Flights from CA $884

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) cost?
You can find cheap one-way flights from CA $222 and cheap return flights from CA $443 BUF to SAN with Expedia. One-way flights typically cost between CA$250 and CA$1336, and return flights often range between CA$571 and CA$1886. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when BUF to SAN ticket fares go up or down.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The cheapest months to fly from BUF to SAN are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Enter BUF to SAN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Sun Country Airlines is one of the cheapest airlines offering connecting return flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.), with tickets starting from around CA$601 for flights that can be booked for departure within the next year. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
While there are no direct flights, you'll find approximately 65 connecting flights per day from Buffalo Niagara Intl. (BUF) to San Diego Intl. (SAN). This gives you plenty of options to choose from. Some common connection points include Baltimore Washington Intl. Thurgood Marshall (BWI), O'Hare Intl. (ORD), and Midway Intl. (MDW).
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) typically departs around 5:00 AM. This service is operated by American Airlines. This is a seasonal service active in August. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
You'll typically find the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) on a Thursday, with around 45 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Southwest Airlines, American Airlines, and United.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
The most popular departure times for flights from Buffalo Niagara Intl. (BUF) to San Diego Intl. (SAN) are in the early morning, from 6am to 9am. Many major carriers, including Southwest Airlines, American Airlines and United, offer flights during this window. Many travellers prefer these early morning flights as they allow you to arrive at your destination with plenty of time to start your day in San Diego.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
There are no nonstop flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.), which is a distance of approximately 3530 kilometres. Flights with one stop typically take around 8 hours 18 minutes. If your journey involves two or more stops, you can expect the travel time to be longer, usually around 12 hours 48 minutes. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
Yes, you can fly business class or first class between Buffalo Niagara Intl. (BUF) and San Diego Intl. (SAN).You can fly business class with Delta.First class cabins are available on:
  • Alaska Airlines
  • Delta
  • United
  • American Airlines

How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Diego, CA (SAN) from Buffalo, NY (BUF)?
If you're planning to travel to San Diego from Buffalo Niagara Intl. (BUF), you can fly directly into San Diego Intl. (SAN). Some flights may connect through major hubs like O'Hare Intl. (ORD), Midway Intl. (MDW), or Baltimore Washington Intl. Thurgood Marshall (BWI) before reaching San Diego. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to San Diego, CA (SAN-San Diego Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
San Diego Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, JetBlue Airways, United
Roundtrip price
CA $442
Distance
3507 km
Average flight time
6 hours 30 mins

Book with confidence

Buffalo to San Diego Flights

The easy way to book your flights from Buffalo to San Diego 

With Expedia, it’s simple to find and book flights to San Diego from Buffalo whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to San Diego Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Buffalo to San Diego today, tomorrow, or this week.  

 

Save dollars with cheap flights from Buffalo Niagara Intl., BUF to San Diego Intl., SAN 

Sort your search results by price to find great deals on your flight from Buffalo to San Diego—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to San Diego from Buffalo currently is just CA $443 rising to CA $838.  

Here are more money-saving tips: 

  • Fly in September when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to San Diego  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to San Diego from Buffalo 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to San Diego with Expedia today.

Buffalo to San Diego Flights

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