
Sikeston Vacation Rentals
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Our top choices for Sikeston vacation homes

1. Little Blue Cottage on Spanish
Little Blue Cottage on SpanishCape Girardeau
8.4 out of 10, Very good, (59 reviews)
The price is CA $114
CA $141 total
includes taxes & fees
Nov 11 - Nov 12

2. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MODexter
10.0 out of 10, Exceptional, (4 reviews)
The price is CA $198
CA $232 total
includes taxes & fees
Nov 16 - Nov 17

3. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & CozyDexter
8.0 out of 10, Very good, (40 reviews)
The price is CA $151
CA $291 total
includes taxes & fees
Nov 11 - Nov 12

4. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Romantic Creekside Retreat | Fireplace | Deck | Pet FriendlyCape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
The price is CA $219
CA $305 total
includes taxes & fees
Nov 11 - Nov 12

5. The Little Château | Woodland Escape
The Little Château | Woodland EscapeCape Girardeau
The price is CA $219
CA $305 total
includes taxes & fees
Nov 11 - Nov 12

6. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & HospitalsCape Girardeau
The price is CA $147
CA $246 total
includes taxes & fees
Nov 16 - Nov 17

7. The Little Cape Lofted Cottage | Creek & Nature
The Little Cape Lofted Cottage | Creek & NatureCape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
The price is CA $227
CA $314 total
includes taxes & fees
Nov 11 - Nov 12

8. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer PoolCape Girardeau
8.8 out of 10, Excellent, (46 reviews)
The price is CA $253
CA $427 total
includes taxes & fees
Nov 11 - Nov 12

9. Beautifully Renovated Farmhouse in Jackson, MO
Beautifully Renovated Farmhouse in Jackson, MOJackson
9.4 out of 10, Exceptional, (3 reviews)
The price is CA $282
CA $422 total
includes taxes & fees
Nov 11 - Nov 12

10. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + MoreCape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
The price is CA $507
CA $782 total
includes taxes & fees
Nov 11 - Nov 12

11. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!New Madrid
10.0 out of 10, Exceptional, (1 review)
The price is CA $282
CA $499 total
includes taxes & fees
Nov 11 - Nov 12

12. Peach Tree Inn, downtown Cobden
Peach Tree Inn, downtown CobdenCobden
10.0 out of 10, Exceptional, (3 reviews)
The price is CA $262
CA $313 total
includes taxes & fees
Nov 17 - Nov 18

13. Hunting / Fishing Cabin at Lake Wappapello
Hunting / Fishing Cabin at Lake WappapelloWilliamsville
8.0 out of 10, Very good, (1 review)
The price is CA $186
CA $337 total
includes taxes & fees
Nov 11 - Nov 12

14. Stunning 2 bedroom in town, close to Shawnee National Forest
Stunning 2 bedroom in town, close to Shawnee National ForestJonesboro
10.0 out of 10, Exceptional, (15 reviews)
The price is CA $194
CA $387 total
includes taxes & fees
Nov 11 - Nov 12

15. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto PassAlto Pass
10.0 out of 10, Exceptional, (5 reviews)
The price is CA $247
CA $354 total
includes taxes & fees
Nov 24 - Nov 25

16. Cozy and Updated Farmhouse with King Suite
Cozy and Updated Farmhouse with King SuiteAnna
10.0 out of 10, Exceptional, (30 reviews)
The price is CA $141
CA $227 total
includes taxes & fees
Nov 16 - Nov 17

17. The Weber Farm - Enjoy a beautiful 100 acre farm!
The Weber Farm - Enjoy a beautiful 100 acre farm!Frohna
10.0 out of 10, Exceptional, (34 reviews)
The price is CA $184
CA $285 total
includes taxes & fees
Dec 1 - Dec 2

18. Magical Victorian near hiking / wine trail
Magical Victorian near hiking / wine trailAnna
10.0 out of 10, Exceptional, (21 reviews)
The price is CA $251
CA $471 total
includes taxes & fees
Nov 15 - Nov 16

19. Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda
Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful MakandaMakanda
10.0 out of 10, Exceptional, (3 reviews)
The price is CA $152
CA $180 total
includes taxes & fees
Nov 16 - Nov 17

20. The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit
The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire PitMurphysboro
8.0 out of 10, Very good, (1 review)
The price is CA $138
CA $321 total
includes taxes & fees
Dec 1 - Dec 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Drury Inn & Suites Jackson MO
10/10 Excellent
Find out more about Sikeston
Sikeston Vacation Homes information
Number of reviews | 261 |
|---|---|
Accommodation | 101 Vacation Homes |
Lowest Price | CA $141 |
Highest Price | CA $782 |
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