Title: Cape Girardeau County B&B: Find the Best Bed and Breakfast from CA $428 | Expedia.ca [Cape Girardeau County Hotels](https://expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations)[Vacation Rentals in Cape Girardeau County](https://expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Vacation-Rental-Destinations)[Cape Girardeau County Car Rentals](https://expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Rental-Destinations)[Cape Girardeau County Vacations](https://expedia.ca/Cape-Girardeau-County.d553248635976430467.Destination-Travel-Guides) ![Beautiful city by the Mississippi River](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Alice Burghart ![](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976430467&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Cape Girardeau County ![Aerial Photo of Cape Girardeau, Missouri, USA](https://images.trvl-media.com/place/820/34f5c59a-7e57-4244-94c6-c657830fc4ab.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Cape Girardeau [](https://expedia.ca/Cape-Girardeau-Bed-And-Breakfast.d820-aaBedAndBreakfast.Travel-Guide-Accommodation) ![Aerial view of Jefferson City, Missouri. Jefferson City is the capital of the U.S. state of Missouri](https://images.trvl-media.com/place/55765/5f6b269f-10cd-40c4-92f0-0144e4b2f10b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Jackson [](https://expedia.ca/Jackson-Bed-And-Breakfast.d55765-aaBedAndBreakfast.Travel-Guide-Accommodation) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Chaffee [](https://expedia.ca/Chaffee-Bed-And-Breakfast.d553248634983269107-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Our top choices for Cape Girardeau County bed & breakfast ![Front of property - evening/night](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/d6ab8f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Cottage, 1 King Bed, Non Smoking (Indigo Cottage) | Living area](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/addd1b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Cottage, 1 King Bed, Non Smoking (Indigo Cottage)](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/04e4b463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/5b224348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Makanda Inn [](https://www.expedia.ca/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) Makanda 10/10 Exceptional (35 reviews) "I had a great stay - wonderful hosts and yummy breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $375 CA $428 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/4a21c2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/52f8e913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/bafa9f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/105000000/104870000/104861900/104861889/93fedf26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks [](https://www.expedia.ca/Jonesboro-Hotels-Nannys-Place-Back-Home-Getaway-In-The-Heart-Of-Wine-Trails-And-Parks.h104861889.Hotel-Information) Jonesboro 10/10 Exceptional (3 reviews) "Very friendly hosts. Met them and they were a pleasure to interact with. They had one of the most complete array of amenities that we have ever encountered in our trips! We did have some issues with losing TV service on our last night, but I imagine that it was not their fault.All in all a pleasant experience." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy S. [](https://www.expedia.ca/Jonesboro-Hotels-Nannys-Place-Back-Home-Getaway-In-The-Heart-Of-Wine-Trails-And-Parks.h104861889.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/dfef2a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/8eebe887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/915f3c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/122000000/121220000/121213100/121213046/9a4aea52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks [](https://www.expedia.ca/Jonesboro-Hotels-Nannys-Place-Cozy-Rustic-Getaway-BB-By-Shawnee-Hills-Wine-Trail-And-Parks.h121213046.Hotel-Information) Jonesboro 10/10 Exceptional (1 review) "Property is super cute. Check in was easy. Host communicated very quickly. Had everything you would need to stay for an extended period of time. Delicious zucchini bread provided for breakfast. Easy to find. Would definitely stay here again if we are ever back in Southern Illinois." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mandy H. [](https://www.expedia.ca/Jonesboro-Hotels-Nannys-Place-Cozy-Rustic-Getaway-BB-By-Shawnee-Hills-Wine-Trail-And-Parks.h121213046.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/f687f700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/13d20663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/a9916bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108480000/108477600/108477548/cc4df203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Charming-1-Bedroom-BB-With-AC.h108477548.Hotel-Information) Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Charming-1-Bedroom-BB-With-AC.h108477548.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27®ionId=553248635976430467&adults=2&lodging=BED_AND_BREAKFAST&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_553248635976430467) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCape-Girardeau-County-Bed-And-Breakfast.d553248635976430467-aaBedAndBreakfast.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCape-Girardeau-County-Bed-And-Breakfast.d553248635976430467-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Top Cape Girardeau County Hotel Reviews ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Everything about this place is great! Highly recommend-you wouldn’t be disappointed " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Clean, roomy and priced right. " [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was great. The facility was excellent. The people were excellent. Definitely going back." [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Room was very clean. Staff was very knowledgeable and courteous. Excellent staff in every department. " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Convenient location, clean room, and easy check in/out process. Really cool little downtown." [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "The hotel was so nice! We planned this trip for my husbands 40th birthday, and I called ahead to see if they did anything for birthdays and they gave us a complementary upgrade on our room. I was taken back on that and thought it was so kind and generous. I wasn’t expecting that - I would have been fine with some cookies and a sign that said happy birthday! We really appreciate everyone and their generosity for us. We definitely will be staying again!!" [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Hampton Inn Cape Girardeau I 55 East](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 10/10 Excellent "Nice staff. Clean room. Good cookies. And breakfast adequate. " [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "The lady at the front desk was an amazing person and treated me with the upmost respect " [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ## Find out more about Cape Girardeau County ## Cape Girardeau County B&B information | Number of reviews | 38 | | ----------------- | ------- | | Accommodation | 5 B&B | | Lowest Price | CA $428 | | Highest Price | CA $428 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [B&B in Advance ](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Advance ](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - 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