Beginning of main content

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Buffalo Business Hotels

See all 134 Hotels in Buffalo
Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst

5020 Main Street, Amherst
3.5 out of 5.0
4.7 out of 5 (469 reviews)
Nice hotelEnjoyed our one night stay. Would have preferred a one bedroom suite as we are used to a bigger room. Room was clean . Television had all the channels . Breakfast was decent but was disappointed they didn’t offer bagels. Will stay again especially if they introduce bagels to the breakfast :)
  20 Feb 2018

C$141

C$141
Aloft Buffalo Airport

Aloft Buffalo Airport

4219 Genesee Street, Cheektowaga
3.5 out of 5.0
4.4 out of 5 (462 reviews)
Excellent, clean room and a reimagined hotel experience
  19 Feb 2018

C$130

C$130
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

Two Fountain Plaza, Buffalo
3.5 out of 5.0
4.2 out of 5 (1,678 reviews)
Close to downtown eventsStaff was great. Room was unimpressive. Bathroom door had hair on it.Room was tidy but didn’t look clean. Good thing I’m a early riser, water pipes were making a racket when neighbors were showering.
  17 Feb 2018

C$149

C$149
Adam's Mark Buffalo

Adam's Mark Buffalo

120 Church St, Buffalo
3.5 out of 5.0
3.5 out of 5 (2,932 reviews)
Everything was great hotel staff was amazingThe hotel staff made sure I was comfortable and safe! They were pleasant and very understanding!
  19 Feb 2018

C$88

C$88
Courtyard by Marriott Buffalo Amherst/University

Courtyard by Marriott Buffalo Amherst/University

4100 Sheridan Dr, Amherst
3.0 out of 5.0
4.3 out of 5 (226 reviews)
My time spent at the hotel for a week was relaxing, comfortable and welcoming.
  31 Jan 2018

C$115

C$115
Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown

10 Lafayette Square, Buffalo
3.5 out of 5.0
4.4 out of 5 (367 reviews)
Stay for hockey gameVery close to arena took trolley right outside door . Grandson got game puck and stick. Hotel has only valet but meter parking free on weekend
  5 Feb 2018

C$134

C$134
Holiday Inn Express Cheektowaga North East

Holiday Inn Express Cheektowaga North East

83 Anderson Rd, Cheektowaga
3.0 out of 5.0
4.5 out of 5 (465 reviews)
Convenient and ModernOur stay was pleasant. We were greeted by a very friendly concierge who gave us our room keys and directed us in the direction of the elevators. When we settled in, we noticed the nice, modern decor. It looked quite clean, however, when taking a closer look, there were quite a bit of white stains ...
  19 Feb 2018

C$114

C$114
Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY

164b Slade Ave, West Seneca
3.0 out of 5.0
4.6 out of 5 (1,451 reviews)
Great check in, the clerk was extremely friendly & accomodating!!
  19 Feb 2018

C$95

C$95
Hampton Inn & Suites Buffalo Airport

Hampton Inn & Suites Buffalo Airport

133 Buell Avenue, Cheektowaga
3.0 out of 5.0
4.5 out of 5 (635 reviews)
Great hotel! Very conveniently located across the street from the airrport. Friendly staff and always hot coffee to take the bite out of a wintertime Buffalo visit.
  30 Jan 2018

C$111

C$111
Comfort Suites Buffalo Airport

Comfort Suites Buffalo Airport

901 Dick Rd, Cheektowaga
3.0 out of 5.0
3.6 out of 5 (1,066 reviews)
DisappointedThe room was clean. The lady at the front desk was helpful but never smiled while I was there. I chose this hotel specifically for the pool and hot tub only to find out that it was under renovation. The free breakfast did not offer eggs, sausage or bacon. They also did not refill the breakfast items ...
  20 Feb 2018

C$71

C$71
Map

Recently booked Buffalo hotels

Red Roof PLUS+ University at Buffalo - Amherst
2.5 out of 5.0
Last booking: 7 minutes ago
Red Roof Inn Buffalo - Niagara Airport
2.5 out of 5.0
Last booking: 25 minutes ago
Hotel at the Lafayette A Trademark Collection Hotel
4.0 out of 5.0
Last booking: 3 hours ago
Adam's Mark Buffalo
3.5 out of 5.0
Last booking: 3 hours ago
Hampton Inn & Suites Buffalo Downtown
3.5 out of 5.0
Last booking: 3 hours ago
Homewood Suites by Hilton Buffalo Airport
3.0 out of 5.0
Last booking: 4 hours ago
Days Hotel Buffalo Airport
3.5 out of 5.0
Last booking: 4 hours ago
Embassy Suites Buffalo
4.0 out of 5.0
Last booking: 4 hours ago
Motel 6 Hamburg, NY
2.0 out of 5.0
Last booking: 4 hours ago

Business Hotel Guide in Buffalo

You’ll command the attention of your colleagues when you host your next seminar or meeting in Buffalo, New York.

  • Search over 134 business hotels in Buffalo
  • Earn props from your peers when you select the best deal
  • Benefit from Expedia+ like upgraded hotels

Buffalo’s hotel meeting rooms and business facilities will ensure you get your deal or conference off to a good start.

The city itself is a prime place to host a gathering of collaborators. It’s right on the border of the United States and Canada, making it an ideal “meet in the middle” spot for intercontinental business. Buffalo’s downtown area has also been heavily revitalized over the years, including improvements to the marinas and other public spaces, so you’ll have plenty of places to bring the best and brightest of your field after a long day at work.

Large Rooms

Get your conference or seminar off on the right foot. Hotels in Buffalo offer just the right size of room for the numbers you’re bringing with you; do you need to host a couple dozen coworkers, or are you looking at an industry-wide gathering of 200-plus people? Conference rooms come equipped with state-of-the-art audiovisual equipment will make your presentation a snap. Make catering arrangements with the hotel kitchen or one of the many restaurants in the downtown area, and join your colleagues for a hot cup of coffee in the morning before the real work begins.

Smaller Rooms

If you’re not getting together a large group of people. Buffalo’s business hotels have the perfect accommodations for a day office. Book an executive suite to use as a training room, or just grab a few hours alone with a computer and a Wi-Fi connection and print out the materials you need to impress your boss or client. Once you’re done with your work, celebrate with a visit to Canalside, the city’s riverfront district. There you’ll find food, drinks, shopping, and everything else you need to take your mind off work.

Speaking of work, you can really get your business trip off on the right foot when you book through Expedia.ca. We get you the cheapest deals on hotels in Buffalo, meaning your business budget stays trim—a fact that’s sure to please your employer. Save money when you book and have more to spend when you take your colleagues out for drinks at one of the pubs on Elmwood Street.