2 Stars Hotels in Cape Girardeau, Missouri from CA $83

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 8 - Nov 9
Tomorrow
Nov 9 - Nov 10
Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Our top choices for Cape Girardeau 2-star hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,001 reviews)
"The stay was pleasant from start to finish. Extremely nice staff, good breakfast and convenient parking. The location was also great!"
United States
Celeste
The price is CA $102
CA $115 total
includes taxes & fees
Nov 15 - Nov 16
Pear Tree Inn Cape Girardeau West
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is CA $134
CA $153 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

3. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
"Nice clean room"
United States
James
The price is CA $100
CA $121 total
includes taxes & fees
Nov 22 - Nov 23
Candlewood Suites Cape Girardeau by IHG
A modern retail area with a display of local items and snacks.

4. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (200 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is CA $120
CA $137 total
includes taxes & fees
Nov 15 - Nov 16
Tru By Hilton Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

5. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (819 reviews)
"Clean rooms, nice staff"
United States
Dayanita
The price is CA $84
CA $95 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Cape Girardeau North
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

6. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (858 reviews)
"Everything was lovely. Great room, breakfast, pool, and staff."
United States
Vonnie
The price is CA $138
CA $156 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn Cape Girardeau I 55 East
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

7. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (243 reviews)
"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."
United States
Jaime
The price is CA $99
CA $116 total
includes taxes & fees
Nov 9 - Nov 10
Town House Inn Cape Giradreau
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

8. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (451 reviews)
"Great owners "
United States
Jennifer
The price is CA $112
CA $121 total
includes taxes & fees
Nov 9 - Nov 10
Town House Inn
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

9. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"
United States
Jeff
The price is CA $106
CA $115 total
includes taxes & fees
Dec 6 - Dec 7
Comfort Suites Jackson-Cape Girardeau
An indoor swimming pool with clear water, marked lanes, and a lifeguard warning sign.

10. Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (245 reviews)
"Staff were very accommodating and made the stay very pleasant."
United States
Dorothy J
Hotel 7 Inn Anna
A rustic interior with a high ceiling, wooden beams, and a central table with chairs.

11. Giant City Lodge

Giant City Lodge
2.5 star property
Cobden
9.0 out of 10, Wonderful, (72 reviews)
"The lodge is very cozy and the restaurant is top-notch. Cabin was small but comfortable. Beautiful location in the middle of a state park. My only recommendation is they need more chairs and benches around the property for those who want to read or rest under the trees."
United States
Christopher S
Giant City Lodge
A rustic wooden cabin with a porch, outdoor seating, and a view of a lush green landscape.

12. Private Getaway on 270 Acres w/ Lake: Swim & Canoe

Private Getaway on 270 Acres w/ Lake: Swim & Canoe
2.0 star property
Advance
Private Getaway on 270 Acres w/ Lake: Swim & Canoe

Top Cape Girardeau Hotel Reviews

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau

10/10 Excellent

Good place, and good breakfast.
Canada
Patricio
Reviewed June 26, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Find out more about Cape Girardeau

Want to get out of town on the cheap? Thanks to the low rates and great discounts at the top 2 Stars hotels in Cape Girardeau, Cape Girardeau you can sneak away on the trip of your dreams with plenty of cash to spare. In addition to the friendly staff and well-maintained surroundings, you’ll find comfortable rooms, complimentary bath products, and quiet sleeping areas, so you can kick back with all the basic conveniences after a long day. Plus, these properties are perfect, if you need a jumping-off point for exploring the local attractions.

Several of the best hotels with 2 Stars in Cape Girardeau are situated just a stone’s throw from both public transportation and the city’s main freeways. Use the travel tools at Expedia.ca to search for options near your favorite neighborhood, find a cheap deal, and book your room. You won’t believe how inexpensive your next vacation can be when you settle in at a top two star hotel in Cape Girardeau.

Explore a world of travel with Expedia