Upstate South Carolina Vacation Rentals

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Check prices for these dates

Next weekend
Sep 5 - Sep 7
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Sep 12 - Sep 14
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Sep 26 - Sep 28
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Oct 24 - Oct 26

Browse Select Upstate South Carolina Vacation Homes

Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is CA $103
CA $551 total
includes taxes & fees
Aug 26 - Aug 27
Lake Hartwell Frank Howard Home Clemson
Family-Friendly 3/2 Home Near Prisma, Fenced Yard
Private kitchen

Family-Friendly 3/2 Home Near Prisma, Fenced Yard

10.0 out of 10, Exceptional, (3)
"The place was perfect! Had everything we needed and was extremely clean!"
The price is CA $137
CA $424 total
includes taxes & fees
Aug 27 - Aug 28
Family-Friendly 3/2 Home Near Prisma, Fenced Yard
Cottage by the lakeshore with a private hot tub!
Property grounds

Cottage by the lakeshore with a private hot tub!

2.0 star property
8.8 out of 10, Excellent, (8)
"The cottage by the lake shore was a great place to stay for the weekend in a beautiful area right up the hill from the lake."
The price is CA $153
CA $268 total
includes taxes & fees
Aug 26 - Aug 27
Cottage by the lakeshore with a private hot tub!
Cozy 2 bedroom home near downtown Gaffney.
Smart TV, video games, Netflix, streaming services

Cozy 2 bedroom home near downtown Gaffney.

9.8 out of 10, Exceptional, (27)
"Very nice Property. Very spacious and beds were super comfortable. Would definitely stay again, thank you so much for being such a awesome host."
The price is CA $137
CA $316 total
includes taxes & fees
Aug 27 - Aug 28
Cozy 2 bedroom home near downtown Gaffney.
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
1 bedroom, iron/ironing board, WiFi, bed sheets

Boutique hotel in historic downtown Seneca. Room #5, two King beds.

9.8 out of 10, Exceptional, (12)
"Great place to stay in Seneca. Very clean, comfortable beds, great location. Will definitely stay again!"
The price is CA $180
CA $285 total
includes taxes & fees
Sep 14 - Sep 15
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Hobbit Hideaway - Do Something Different!
Property grounds

Hobbit Hideaway - Do Something Different!

10.0 out of 10, Exceptional, (46)
"Everything about this place was great!"
The price is CA $106
CA $230 total
includes taxes & fees
Sep 7 - Sep 8
Hobbit Hideaway - Do Something Different!
Private Room #3
1 bedroom, iron/ironing board, WiFi, bed sheets

Private Room #3

9.2 out of 10, Wonderful, (10)
"More like a hotel room which was just perfect for our visit for Clemson graduation"
The price is CA $194
CA $308 total
includes taxes & fees
Aug 26 - Aug 27
Private Room #3
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Exterior

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

10.0 out of 10, Exceptional, (41)
"Spotless with huge private yard. Has almost every convenience - no icemaker so bring bagged ice if needed. Quick drive to downtown. "
The price is CA $136
CA $293 total
includes taxes & fees
Aug 31 - Sep 1
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Outdoor spa tub

⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg

10.0 out of 10, Exceptional, (38)
"Came here to be close to the airport and relax before family wedding. "
The price is CA $124
CA $284 total
includes taxes & fees
Aug 26 - Aug 27
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Charming luxury cottage in the heart of Boiling Springs
Property grounds

Charming luxury cottage in the heart of Boiling Springs

9.0 out of 10, Wonderful, (4)
"The location is great, and the place was very nice as well. Would recommend!"
The price is CA $124
CA $270 total
includes taxes & fees
Aug 28 - Aug 29
Charming luxury cottage in the heart of Boiling Springs
Boutique hotel in historic downtown Seneca. Room #4, King bed.
1 bedroom, iron/ironing board, WiFi, bed sheets

Boutique hotel in historic downtown Seneca. Room #4, King bed.

9.4 out of 10, Exceptional, (11)
"Enjoyed our stay. The only improvements that could be made was better lighting. With no windows in the unit, it was a little dark. Also it would have been nice to have a box of Kleenex for our use. Not a deal killer."
The price is CA $180
CA $290 total
includes taxes & fees
Aug 26 - Aug 27
Boutique hotel in historic downtown Seneca. Room #4, King bed.
Field Trip Unit 9 Small Bell Tent
Sauna

Field Trip Unit 9 Small Bell Tent

10.0 out of 10, Exceptional, (3)
"Hot tub, sauna and cold plunge are really nice. Bathrooms are clean and nice. I was able to work remotely in their clubhouse with fast internet. "
The price is CA $168
CA $276 total
includes taxes & fees
Aug 26 - Aug 27
Field Trip Unit 9 Small Bell Tent
Modern Farmhouse in Downtown Simpsonville, SC
Fridge, microwave, oven, stovetop

Modern Farmhouse in Downtown Simpsonville, SC

10.0 out of 10, Exceptional, (38)
"This little house was exactly as described, cozy and clean. This was my first VRBO stay, and this booking did not disappoint. It was also a nice place to book because I was traveling with my pets. They enjoyed the backyard and also felt at home. "
The price is CA $163
CA $411 total
includes taxes & fees
Aug 28 - Aug 29
Modern Farmhouse in Downtown Simpsonville, SC
The Clemson Cottage - 3.6 mi. to Memorial Stadium
Private kitchen

The Clemson Cottage - 3.6 mi. to Memorial Stadium

10.0 out of 10, Exceptional, (12)
"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "
The price is CA $249
CA $548 total
includes taxes & fees
Aug 26 - Aug 27
The Clemson Cottage - 3.6 mi. to Memorial Stadium
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Property grounds

Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

10.0 out of 10, Exceptional, (4)
"Great place and even better hosts! This place is unique and will make you never want to stay in a hotel again. "
The price is CA $143
CA $267 total
includes taxes & fees
Aug 26 - Aug 27
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Private family, pet friendly with fenced yard near Limestone College and Outlets
Fridge, microwave, oven, stovetop

Private family, pet friendly with fenced yard near Limestone College and Outlets

9.8 out of 10, Exceptional, (23)
"Visiting our daughter at Limestone with family! Perfect location clean and comfortable! Host is very nice and accommodating to all our requests during our stay! Will be back for sure! "
The price is CA $111
CA $282 total
includes taxes & fees
Aug 29 - Aug 30
Private family, pet friendly with fenced yard near Limestone College and Outlets
Treetop Getaway w/ Hot Tub • Peaceful retreat
Terrace/patio

Treetop Getaway w/ Hot Tub • Peaceful retreat

The price is CA $260
CA $528 total
includes taxes & fees
Aug 31 - Sep 1
Treetop Getaway w/ Hot Tub • Peaceful retreat
Sunny Side Cottage: Cozy Stay by Anderson U!
Fridge, microwave, oven, stovetop

Sunny Side Cottage: Cozy Stay by Anderson U!

9.8 out of 10, Exceptional, (16)
"Great location to downtown Anderson! Lovely neighborhood. Charming home! Would stay here again!"
The price is CA $155
CA $501 total
includes taxes & fees
Aug 27 - Aug 28
Sunny Side Cottage: Cozy Stay by Anderson U!
Boutique hotel in historic downtown Seneca. Room #6, King Bed.
1 bedroom, iron/ironing board, WiFi, bed sheets

Boutique hotel in historic downtown Seneca. Room #6, King Bed.

9.2 out of 10, Wonderful, (20)
"Great room, very clean and comfortable bed!"
The price is CA $180
CA $290 total
includes taxes & fees
Aug 26 - Aug 27
Boutique hotel in historic downtown Seneca. Room #6, King Bed.
Charming historic cottage in Enoree
Fridge, microwave, oven, stovetop

Charming historic cottage in Enoree

The price is CA $133
CA $285 total
includes taxes & fees
Sep 8 - Sep 9
Charming historic cottage in Enoree
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Hilton Greenville

Hilton Greenville

10/10 Excellent
"This is our go-to hotel for all events at Clemson! Amazing hotel with the greatest staff!"
Yvette 1-night trip
Posted 2 days ago
Hilton Greenville