Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from CA $90
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $76
CA $84 total
includes taxes & fees
May 20 - May 21

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $87
CA $95 total
includes taxes & fees
May 20 - May 21

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is CA $218
CA $357 total
includes taxes & fees
May 27 - May 28

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (702 reviews)
The price is CA $116
CA $137 total
includes taxes & fees
Jun 14 - Jun 15

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (230 reviews)
The price is CA $178
CA $195 total
includes taxes & fees
Jun 1 - Jun 2

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (717 reviews)
The price is CA $118
CA $128 total
includes taxes & fees
May 31 - Jun 1

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is CA $169
CA $187 total
includes taxes & fees
May 31 - Jun 1

Clemson Memorabilia House
Clemson Memorabilia HouseClemson
9.6 out of 10, Exceptional, (10 reviews)
The price is CA $122
CA $326 total
includes taxes & fees
Jun 1 - Jun 2

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,005 reviews)
The price is CA $150
CA $186 total
includes taxes & fees
May 27 - May 28

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (791 reviews)
The price is CA $150
CA $168 total
includes taxes & fees
Jun 14 - Jun 15

Baymont by Wyndham Greenwood
Baymont by Wyndham GreenwoodGreenwood
7.6 out of 10, Good, (831 reviews)
The price is CA $98
CA $109 total
includes taxes & fees
May 27 - May 28

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (616 reviews)
The price is CA $151
CA $168 total
includes taxes & fees
May 24 - May 25

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,208 reviews)
The price is CA $151
CA $166 total
includes taxes & fees
May 31 - Jun 1

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,011 reviews)
The price is CA $205
CA $227 total
includes taxes & fees
May 28 - May 29

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,007 reviews)
The price is CA $151
CA $167 total
includes taxes & fees
May 21 - May 22

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (710 reviews)
The price is CA $168
CA $186 total
includes taxes & fees
Jun 7 - Jun 8

Best Western Seneca-Clemson
Best Western Seneca-ClemsonSeneca
8.4 out of 10, Very good, (659 reviews)
The price is CA $134
CA $148 total
includes taxes & fees
May 24 - May 25

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (600 reviews)
The price is CA $181
CA $201 total
includes taxes & fees
May 20 - May 21

Aloft by Marriott Greenville Downtown
Aloft by Marriott Greenville DowntownGreenville Downtown
9.2 out of 10, Wonderful, (1,006 reviews)
The price is CA $178
CA $202 total
includes taxes & fees
May 31 - Jun 1

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (458 reviews)
The price is CA $191
CA $208 total
includes taxes & fees
Jun 4 - Jun 5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (73 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Drury Inn & Suites Greenville
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is CA $81 per night from Jun 14 to Jun 15
CA $81
CA $90 total
Jun 14 - Jun 15
includes taxes & fees
6/10 (601 reviews)
Hotels in Upstate South Carolina with star rating

4 Star Hotels
36 properties
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