Find hotels in Upstate South Carolina, SC from CA $100

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Upstate South Carolina hotels

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.8 out of 10, Excellent, (486 reviews)
"Room very clean staff was great breakfast was really good with lots of options "
United States
melvin
The price is CA $125
CA $136 total
includes taxes & fees
May 21 - May 22
Holiday Inn Express Gaffney by IHG

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (845 reviews)
"We always wanted to stay here whenever we were visiting Clemson, and we finally did … and we’re not disappointed. Our stay was great!"
United States
Roberto
The price is CA $218
CA $242 total
includes taxes & fees
May 17 - May 18
The Inn at Patrick Square

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1,197 reviews)
"The breakfast was amazing the room was clean it’s definitely worth the price"
United States
Kylasha
The price is CA $163
CA $179 total
includes taxes & fees
May 24 - May 25
Embassy Suites Greenville Golf Resort & Conference Center

Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC
2.5 star property
Greer
9.6 out of 10, Exceptional, (457 reviews)
"great service all around."
United States
Alberto
The price is CA $191
CA $208 total
includes taxes & fees
Jun 7 - Jun 8
Hampton Inn Greer Greenville, SC

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (712 reviews)
"Would stay again breakfast was amazing "
United States
Theresa
The price is CA $119
CA $129 total
includes taxes & fees
May 17 - May 18
Hampton Inn Gaffney

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville
2.5 star property
Greer
8.6 out of 10, Excellent, (789 reviews)
"Wonderful stay - everything was perfect "
United States
Paula
The price is CA $139
CA $156 total
includes taxes & fees
May 24 - May 25
Comfort Inn & Suites Greer - Greenville

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel
3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
"Friendly staff, nice facility that is centrally located."
United States
Frederick
The price is CA $164
CA $182 total
includes taxes & fees
May 31 - Jun 1
Inn on the Square, an Ascend Collection Hotel

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (229 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is CA $177
CA $195 total
includes taxes & fees
May 19 - May 20
Fairfield Inn & Suites Seneca Clemson Univ Area

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1,002 reviews)
"Hotel was in good condition, bedrooms were comfortable and the breakfast was suitably varied."
United States
Alexandra
The price is CA $163
CA $181 total
includes taxes & fees
May 17 - May 18
Best Western Plus Clemson Hotel & Conference Center

Deluxe Inn

Deluxe Inn
2.0 star property
Mauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $92
CA $101 total
includes taxes & fees
May 17 - May 18
Deluxe Inn

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (919 reviews)
"Clean Room, Staff, Amazing Breakfast"
United States
Najiea
The price is CA $125
CA $138 total
includes taxes & fees
May 31 - Jun 1
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (1,009 reviews)
"Lovely place to stay right on the lake. "
United States
Sara
The price is CA $204
CA $227 total
includes taxes & fees
May 17 - May 18
Clemson University's James F. Martin Inn

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,001 reviews)
"This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!"
United States
Valarie Tina
The price is CA $149
CA $185 total
includes taxes & fees
May 16 - May 17
Lakeside Lodge Clemson

Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
2.5 star property
Spartanburg
9.2 out of 10, Wonderful, (892 reviews)
"Clean room , friendly staff , great location "
United States
Gerad
The price is CA $142
CA $158 total
includes taxes & fees
Jun 14 - Jun 15
Tru by Hilton Spartanburg

Hampton Inn Easley

Hampton Inn Easley
2.5 star property
Easley
9.2 out of 10, Wonderful, (709 reviews)
"Great staff, left a lasting impression. "
United States
Jenine
The price is CA $167
CA $186 total
includes taxes & fees
Jun 7 - Jun 8
Hampton Inn Easley

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (598 reviews)
"Easy parking, great location. Will stay there again"
United States
William
The price is CA $188
CA $209 total
includes taxes & fees
May 17 - May 18
The Abernathy of Clemson

Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26
2.5 star property
Clinton
7.4 out of 10, Good, (549 reviews)
"Clean room, easy parking, we were plenty comfortable."
United States
Christine
The price is CA $86
CA $101 total
includes taxes & fees
Jun 7 - Jun 8
Quality Inn Clinton - Laurens I-26

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,001 reviews)
"Lovely stay, clean room, quiet property, wonderful pleasant staff and top notch location! "
United States
N
The price is CA $87
CA $97 total
includes taxes & fees
May 18 - May 19
Days Inn by Wyndham Anderson

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.4 out of 10, Very good, (1,001 reviews)
"Front desk staff were very friendly. We had a welcoming and quiet 1 night stay."
United States
Nicole
The price is CA $115
CA $127 total
includes taxes & fees
Jun 14 - Jun 15
Microtel Inn & Suites by Wyndham Anderson/Clemson

Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
2.5 star property
Spartanburg
8.4 out of 10, Very good, (1,000 reviews)
"Nice place for the price "
United States
Brandon
The price is CA $131
CA $148 total
includes taxes & fees
May 25 - May 26
Comfort Suites At WestGate Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Upstate South Carolina

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Upstate South Carolina attractions

Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

More cheap stays in Upstate South Carolina

Hotels in Upstate South Carolina with star rating

Explore a world of travel with Expedia