Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from CA $100
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (486 reviews)
The price is CA $125
CA $136 total
includes taxes & fees
May 21 - May 22

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (845 reviews)
The price is CA $218
CA $242 total
includes taxes & fees
May 17 - May 18

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,197 reviews)
The price is CA $163
CA $179 total
includes taxes & fees
May 24 - May 25

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (456 reviews)
The price is CA $191
CA $208 total
includes taxes & fees
Jun 7 - Jun 8

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (711 reviews)
The price is CA $119
CA $129 total
includes taxes & fees
May 17 - May 18

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (789 reviews)
The price is CA $139
CA $156 total
includes taxes & fees
May 24 - May 25

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is CA $171
CA $190 total
includes taxes & fees
Jun 14 - Jun 15

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (229 reviews)
The price is CA $177
CA $195 total
includes taxes & fees
May 19 - May 20

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,002 reviews)
The price is CA $163
CA $181 total
includes taxes & fees
May 17 - May 18

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $92
CA $101 total
includes taxes & fees
May 17 - May 18

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
8.6 out of 10, Excellent, (919 reviews)
The price is CA $125
CA $138 total
includes taxes & fees
May 31 - Jun 1

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,009 reviews)
The price is CA $204
CA $227 total
includes taxes & fees
May 17 - May 18

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,000 reviews)
The price is CA $149
CA $185 total
includes taxes & fees
May 16 - May 17

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (892 reviews)
The price is CA $140
CA $156 total
includes taxes & fees
Jun 7 - Jun 8

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (709 reviews)
The price is CA $167
CA $186 total
includes taxes & fees
Jun 7 - Jun 8

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (598 reviews)
The price is CA $188
CA $209 total
includes taxes & fees
May 17 - May 18

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (549 reviews)
The price is CA $86
CA $101 total
includes taxes & fees
Jun 7 - Jun 8

Days Inn by Wyndham Anderson
Days Inn by Wyndham AndersonAnderson
8.0 out of 10, Very good, (1,000 reviews)
The price is CA $93
CA $103 total
includes taxes & fees
May 26 - May 27

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.4 out of 10, Very good, (1,001 reviews)
The price is CA $115
CA $127 total
includes taxes & fees
Jun 14 - Jun 15

Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
8.4 out of 10, Very good, (1,000 reviews)
The price is CA $129
CA $146 total
includes taxes & fees
Jun 9 - Jun 10
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (73 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
8/10 Good
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is CA $90 per night from Jun 14 to Jun 15
CA $90
CA $100 total
Jun 14 - Jun 15
includes taxes & fees
6/10 (600 reviews)
Hotels in Upstate South Carolina with star rating

4 Star Hotels
36 properties
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