Title: Book the Best CHEAP Hotels in Upstate South Carolina, SC from CA $107 - Upstate South Carolina Cheap Hotels | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Cheap Hotels in Upstate South Carolina, SC from CA $107 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Cheap Hotels Tonight [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-07&endDate=2025-10-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-08&endDate=2025-10-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Cheap Hotels ![Gazebo](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/4946ef17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/5971f25f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/904caca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/99cd504a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. Greenville 7.4/10 Good (17) "Great place, service, amenities and price!" CA $112 CA $127 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/9b41a13e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/96c48b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/1999d91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Haywood Greenville 7.4/10 Good (1077) "Clean room, nice staff, and convenient location. " CA $105 CA $116 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/164da543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/fe5b957d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6e7a607b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Greenville Greenville 9.6/10 Exceptional (1005) "Kind staff and easy check in." CA $160 CA $176 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/e91d409a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/b54ae3f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville I-385 Inn & Suites Greenville 9.2/10 Wonderful (1365) "It was great Location " CA $131 CA $144 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/3a7e8dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/8449a857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/fd1d83c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites At WestGate Mall Spartanburg 8.2/10 Very good (1004) "Overall experience was great. Staff was friendly and helpful. The room was very clean, comfortable and spacious " CA $130 CA $147 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/41944efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/d16127a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/0aaf2649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel, BW Signature Collection Greenville 8.0/10 Very good (881) "I loved the cozy atmosphere of the property. " CA $97 CA $107 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/800/708/cd95f3b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/4bfc6efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/800/708/c6283d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Greenville Airport Inn Greenville 7.8/10 Good (1005) "Enjoyed my stay. Very clean and quiet stay. " CA $101 CA $111 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/a74bbe34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/704d2b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/b8a8a3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville Downtown Greenville Downtown 9.6/10 Exceptional (1005) "Room was wonderful and staff very nice." CA $205 CA $231 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/14e3230b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/706f626f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/452fcf9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1001) "Great stay" CA $103 CA $115 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/367ed34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/7e931364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/4c9c76a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Greenville Greenville 8.2/10 Very good (1011) "Great place " CA $153 CA $173 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23®ionId=6057939&adults=2&travelerType=budget_property&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Baymont by Wyndham Greenville Woodruff Rd](//images.trvl-media.com/lodging/1000000/20000/12300/12266/e0489212_y.jpg) ### Baymont by Wyndham Greenville Woodruff Rd 10/10 Excellent "Yes!" [](https://expedia.ca/Greenville-Hotels-Baymont-By-Wyndham-Greenville-Woodruff-Rd.h12266.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "I enjoyed my stay here. It was very clean and cozy. I will make another stay here, if available for my next travel. Thank you! " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Very friendly. Great coffee and breakfast. Hotel was clean and convenient " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "I loved my stay here! The rooms are spotless, the staff are so warm and welcoming, and the location is awesome with lots of restaurants and shops nearby. The price is such a great deal—you get free breakfast, dinner, AND three drinks every night! Can’t recommend it enough!" [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Best Western Greenville Airport Inn](//images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f_y.jpg) ### Best Western Greenville Airport Inn 10/10 Excellent "Super easy to get around. Lots of dining options. 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[Hotel Wedding Venues Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Wedding-Hotels.0-0-d6239-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Flights from Donaldson Center](https://www.expedia.ca/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.ca/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Mauldin](https://www.expedia.ca/lp/flights/183944/flights-from-mauldin) - [Flights from Anderson (AND) to Greenville (GDC)](https://www.expedia.ca/lp/flights/and/gdc/anderson-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.ca/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Asheville (AVL) to Greenville (GDC)](https://www.expedia.ca/lp/flights/avl/gdc/asheville-to-greenville) - [Flights from Birmingham (BHM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/bhm/gmu/birmingham-to-greenville) - 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[Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - [Book Cheap Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Cheap-Hotels.0-0-d6057939-tCheapHotels.Travel-Guide-Filter-Hotels)