Title: Book the Best Greenville SPA Resorts from CA $295 - Spa Hotels in Greenville, SC | Expedia.ca [Greenville Travel Guide](https://expedia.ca/Greenville.dx1388)[Hotels in Greenville](https://expedia.ca/Greenville-Hotels.d1388.Travel-Guide-Hotels)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d1388.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights)[Things to do in Greenville](https://expedia.ca/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities)[Greenville Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide)[Greenville Vacation Packages](https://expedia.ca/Greenville.d1388.Destination-Travel-Guides) ![Greenville which includes a marina, general coastal views and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63749-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Greenville, SC from CA $295 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville Spa Hotels Tonight [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-15&endDate=2025-10-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-16&endDate=2025-10-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=1388&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Greenville Spa Hotels ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/924dd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (392) "Very expensive but great location. " CA $406 CA $459 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/aa0a358b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d57fd5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (601) "Wonderful boutique hotel!!" CA $225 CA $295 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/24c29149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/4694c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique Travelers Rest 9.6/10 Exceptional (30) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." CA $616 CA $678 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6030000/6024800/6024754/1ce491f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6030000/6024800/6024754/d6d866df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Two)](https://images.trvl-media.com/lodging/7000000/6030000/6024800/6024754/d87f5526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6030000/6024800/6024754/362cd5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Orchard Inn Saluda 9.4/10 Exceptional (139) "Friendly and helpful staff. Excellent breakfast." CA $420 CA $461 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Asheville-Hotels-The-Orchard-Inn.h6024754.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=1388&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Greenville ### Top Greenville attractions for a relaxing vacation In Greenville, South Carolina, travellers seeking relaxation combined with adventure will find an array of activities to complement their stay in luxurious spa hotels. Begin your day with a rejuvenating visit to the Spa at Westin Poinsett, where you can indulge in signature treatments designed to refresh your body and mind. After your spa experience, take a leisurely stroll along the beautiful Swamp Rabbit Trail, a 22-mile greenway that winds through picturesque landscapes, perfect for a family bike ride or a peaceful walk. For a touch of culture, explore the Greenville County Museum of Art, showcasing an impressive collection of American art, or enjoy a performance at the Peace Center, which hosts a variety of concerts and shows throughout the year. Don’t miss the vibrant Falls Park on the Reedy, where you can relax by the waterfalls and enjoy the stunning views from the Liberty Bridge. The vibrant downtown area is particularly attractive for those looking for hotels with spas, offering a perfect blend of comfort and convenience, allowing you to unwind in style while being just steps away from local shops, restaurants, and entertainment. With such a wealth of experiences tailored for the quality seeker, you’re bound to feel pampered and rejuvenated during your stay. ### Find the best hotels & resorts with spas in Greenville For those seeking relaxation and rejuvenation in Greenville, South Carolina, these top hotels offer exceptional spa experiences tailored to soothe and pamper every traveller. [Hotel Hartness](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) - **Why it's great for tailored spa getaway:** Hotel Hartness stands out as a premier destination for spa enthusiasts, an impressive review rating of 9.8. With a full-service spa offering a variety of treatments including body wraps, scrubs, and massages in dedicated treatment rooms, guests can immerse themselves in relaxation. The hotel also features couples' treatment rooms for a romantic and indulgent experience, ensuring that every traveller leaves feeling refreshed and revitalised. - **Other amenities:** Guests can enjoy a serene terrace, a shared outdoor pool with sun loungers, and 24-hour fitness facilities. Additional features include hydromassage showerheads, designer toiletries, and daily housekeeping for a comfortable stay. For those driving, the hotel provides accessible parking, electric car charging stations, and complimentary RV/bus/truck parking options. - **Nearby attractions:** Pelham Mills Site - 4.1 km, LeMans Karting - 4.3 km [Grand Bohemian Lodge Greenville, Autograph Collection](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) - **Why it's great for tailored spa getaway:** The Grand Bohemian Lodge Greenville is an exquisite retreat for spa lovers, with a stellar review rating of 9.6. This luxurious hotel offers an onsite full-service spa, available daily, where guests can indulge in a range of treatments designed to rejuvenate the mind and body. With its elegant Tudor design and spa offerings, it promises a tranquil getaway in the heart of downtown Greenville. - **Other amenities:** Guests can take advantage of a rooftop garden, 24-hour fitness centre, and valet parking for added convenience. Each room features thoughtful touches such as premium bedding and bathrobes, while the concierge service ensures that all needs are met. The hotel also offers balconies for fresh air and views, making it a perfect choice for relaxation after a day of exploring. - **Neighborhood:** Greenville Downtown - **Nearby attractions:** The Peace Center - 0.6 km, Falls Park on the Reedy - 0 km, Fluor Field at the West End - 1.5 km ## Top Greenville Hotel Reviews ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "The staff were very friendly. I checked out and left my phone in the room and they allowed me to go back in the room, no hassle at all to retrieve my phone!!" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean rooms" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Stayed for a quick stop but everything was good " [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Everything is super nice and clean" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Greenville? > Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away. ### What is the best spa hotel in Greenville? > [Grand Bohemian Lodge Greenville, Autograph Collection](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Another popular spa hotel in Greenville is [Hotel Hartness](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information). ### How many spa hotels will I find in Greenville? > Among Expedia's 658 accommodation options in Greenville, there are 2 spa hotels. ### What's there to see and do in Greenville? > Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate, and Greenville County Museum of Art. If you have some spare time during your trip, you might want to check out Bon Secours Wellness Arena and Greenville Zoo. ### What is a Greenville spa hotel? > Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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