Title: 4 Stars Hotels in Upstate South Carolina, South Carolina from CA $188 - Find Cheap Upstate South Carolina Hotels With 4 Stars | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Upstate South Carolina, South Carolina from CA $188 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina 4 Star Hotels Tonight [Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-20&endDate=2025-10-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-21&endDate=2025-10-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina 4 Star Hotels ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/dd539dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (394) "Very expensive but great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Ellen CA $405 CA $458 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Superior Room, 2 Queen Beds](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/ee0e0eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson Clemson 9.8/10 Exceptional (708) "Very nice hotel, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin CA $265 CA $294 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/93cc35df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/02c3589b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville Greenville Downtown 9.2/10 Wonderful (1005) "Very courteous and helpful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANDREW CA $293 CA $322 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/6b940d91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (604) "Wonderful boutique hotel!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Ellen CA $212 CA $281 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/9b7f0f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/6ae08031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/d99800f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/9207bf75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Marriott Greenville 8.6/10 Excellent (600) "we enjoyed the bar" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $171 CA $188 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information) ![Two Bedroom Suite](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a4b477d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/18a2116d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Two Bedroom Suite | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/f7ce884a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a1a743d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville - Downtown Greenville Downtown 9.2/10 Wonderful (750) "Excellent stay as always! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elena CA $182 CA $205 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson Clemson 9.6/10 Exceptional (548) "Great place for visiting the university " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Guy CA $193 CA $215 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Apartment, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/39a13760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/689c7682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/7d816d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/6a920723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Place Apartments by Landing Greenville 7.8/10 Good (40) "This was false advertising. Property name is not the same and their app did not work and we could not get into the property NOR get anyone on the phone. We spent 2 hours on the phone to try and get in and finally had to book another hotel. And it’s been a week and my money has yet to be returned even though Expedia said they would refund me " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley [](https://www.expedia.ca/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a75f160d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/8c83b96e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast Pendleton 10/10 Exceptional (75) "Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $168 CA $257 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/24c29149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique Travelers Rest 9.6/10 Exceptional (30) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck CA $615 CA $677 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![ADA Vista Wedge Cottage](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/38cc695c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels Travelers Rest 10/10 Exceptional (12) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $267 CA $410 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/ed9aaf39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/5d51f2ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Private kitchen](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/1d672e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Private kitchen](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/e9f9aeba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 228 Lakeland Anderson [](https://www.expedia.ca/Anderson-Hotels-228-Lakeland.h111438806.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels) ## Learn more about Upstate South Carolina Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina. [See all hotels in Upstate South Carolina](https://www.expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&adults=2®ionId=553248635975748552) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by South Carolina Department of Parks, Recreation & Tourism ## Top Upstate South Carolina Hotel Reviews ![Grand Bohemian Lodge Greenville, Autograph Collection](//images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Excellent welcome at check in. Very clean room and all hotel areas. " [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ## Find out more about Upstate South Carolina If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Upstate South Carolina are calling your name. Known for providing first-rate service in amazing locations, each of the Upstate South Carolina 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Upstate South Carolina. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Upstate South Carolina, South Carolina, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Upstate South Carolina hotels with 4 Stars provide everything you need to unwind in style. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Belvedere](https://www.expedia.ca/3Star-Belvedere-Hotels.s30-0-d553248634999443381.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Blacksburg](https://www.expedia.ca/3Star-Blacksburg-Hotels.s30-0-d183936.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Greenville](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Highland](https://www.expedia.ca/3Star-Highland-Hotels.s30-0-d553248635975852355.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Ninety Six](https://www.expedia.ca/3Star-Ninety-Six-Hotels.s30-0-d6348007.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Saluda](https://www.expedia.ca/4Star-Saluda-Hotels.s40-0-d3000456071.Travel-Guide-Filter-Hotels) - 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[B&B in Gray Court](https://www.expedia.ca/Gray-Court-Bed-And-Breakfast.d553248634998649725-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Luxury Hotels in Gray Court](https://www.expedia.ca/Gray-Court-Hotels-Luxury-Hotel.0-0-d553248634998649725-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Gray Court Hotels](https://www.expedia.ca/Gray-Court-Hotels.d553248634998649725.Travel-Guide-Hotels) - [Moore Hotels](https://www.expedia.ca/Moore-Hotels.d553248635975869508.Travel-Guide-Hotels) - [Farmstay in Pauline](https://www.expedia.ca/Pauline-Agritourism.d3000353200-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Pauline](https://www.expedia.ca/Pauline-Bed-And-Breakfast.d3000353200-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Pauline Hotels](https://www.expedia.ca/Pauline-Hotels.d3000353200.Travel-Guide-Hotels) - [B&B in Reidville](https://www.expedia.ca/Reidville-Bed-And-Breakfast.d3000353212-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Reidville](https://www.expedia.ca/Reidville-Guest-Houses.d3000353212-aaGuestHouses.Travel-Guide-Accommodation) - 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