Title: Book the Best Upstate South Carolina SPA Resorts from CA $167 - Spa Hotels in Upstate South Carolina, SC | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Spa Hotels Tonight [Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-27&endDate=2026-01-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-28&endDate=2026-01-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-30&endDate=2026-02-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-02-06&endDate=2026-02-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina hotels with a spa ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/b8d82b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (31 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck CA $377 CA $415 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/75814e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (439 reviews) "Awesome place and service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $290 CA $328 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/0d84d9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (641 reviews) "The hotel was clean staff was amazing room was outstanding." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford CA $232 CA $301 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Standard Studio, 1 King Bed with Sofa bed, Slope side | Terrace/patio](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/24255478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cabin, Non Smoking](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/51fa3dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, memory foam beds, individually decorated](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/98196a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/4020b7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SKYLARANNA Resort & Spa [](https://www.expedia.ca/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) Hendersonville 8.2/10 Very good (354 reviews) "The staff was amazing! Fast resolution to any problem or mishap, with very kind and sincere generosity. We had a wonderful stay and loved the rooms view that we had. Perfect stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charity CA $113 CA $167 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) ![Couples treatment rooms, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/b51de8d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/2cd775cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/cf667612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/9fc2aad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Lure Inn & Spa [](https://www.expedia.ca/Lake-Lure-Hotels-Lake-Lure-Inn-And-Spa.h107204500.Hotel-Information) Lake Lure 8.4/10 Very good (96 reviews) "Love the old charm of this inn." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer [](https://www.expedia.ca/Lake-Lure-Hotels-Lake-Lure-Inn-And-Spa.h107204500.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/fe5dc4ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/8063695a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/764f9317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Bedrooms (The Lady Anne Room)](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/a490469b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Morgan and Wells B&B [](https://www.expedia.ca/Shelby-Hotels-Morgan-And-Wells-BB.h11043190.Hotel-Information) Shelby 9.6/10 Exceptional (91 reviews) "We came up to celebrate my mom's 74th birthday and had a lovely stay in the Lady Ann Suite. Ronnie greeted us as we arrived, and we enjoyed family style breakfast and conversation with other guests." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel CA $174 CA $196 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Shelby-Hotels-Morgan-And-Wells-BB.h11043190.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/c44295fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/20aae6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/dc8914e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/3c755149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kingwood Resort [](https://www.expedia.ca/Helen-Hotels-Kingwood-Resort.h921807.Hotel-Information) Clayton 8.0/10 Very good (424 reviews) "the staff were very friendly! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jossue CA $220 CA $279 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Helen-Hotels-Kingwood-Resort.h921807.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/ff050b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/4cb33cd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed, Private Bathroom](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/69c5adfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/w796h532x0y0-55144a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sylvan Falls Mill B&B [](https://www.expedia.ca/Helen-Hotels-Sylvan-Falls-Mill-BB.h15825932.Hotel-Information) Rabun Gap 9.6/10 Exceptional (73 reviews) "Linda and Mike were outstanding hosts and welcoming to us. They were accommodating to special diet needs, and anxious to meet our requests. Food was delicious, the sitting area was cozy and our room was perfect. If it were possible we’d give 10 stars. Mike us a tour of the mill and a history of the property that made the whole experience fulfilling. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $253 CA $298 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Helen-Hotels-Sylvan-Falls-Mill-BB.h15825932.Hotel-Information) ![1 treatment room, massages](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/7f348ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/1b011f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/5f74fd6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/f1c0642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1898 Waverly Inn [](https://www.expedia.ca/Asheville-Hotels-1898-Waverly-Inn.h898978.Hotel-Information) Hendersonville 9.4/10 Exceptional (291 reviews) "Everything - from check in to check out was excellent! Evening wine and breakfast was delicious!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $172 CA $194 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Asheville-Hotels-1898-Waverly-Inn.h898978.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/70dd5eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/bb03cfdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/87372292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/e4c70367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greystone Inn [](https://www.expedia.ca/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) Lake Toxaway 9.4/10 Exceptional (86 reviews) "Magnificent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $341 CA $427 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11®ionId=6057939&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Upstate South Carolina ### Top Upstate South Carolina attractions for a relaxing vacation Upstate South Carolina is a hidden gem for travellers seeking a blend of relaxation and adventure, particularly those keen on spa hotels. Start your journey in Greenville, where the vibrant downtown area offers a stunning 32-foot waterfall in Falls Park, perfect for a leisurely stroll before indulging in a revitalising spa treatment at one of the local hotels. For outdoor enthusiasts, the Blue Ridge Mountains provide breathtaking views and hiking trails, allowing for a rejuvenating escape into nature, followed by a soothing massage at a nearby resort. If you're travelling with family, take a trip to the Greenville Zoo, where you can enjoy a relaxing afternoon before unwinding at a hotel spa that caters to both adults and children. Don’t miss the charming town of Spartanburg, known for its rich history and cultural festivals, where you can explore art galleries and enjoy local cuisine, all within reach of luxurious accommodations featuring spa services. The area around Lake Hartwell offers water activities and scenic picnic spots, making it a delightful base to relax and recharge after a day of adventure. Whether you choose to stay in Greenville or Spartanburg, the quality of service and the range of pampering options available in Upstate South Carolina will ensure an enriching and memorable experience. ## Top Upstate South Carolina Hotel Reviews ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Room was spotless, staff was great, love the shower gel and shampoo! Always a good time at this facility - you never need to go out the hotel provides it all!" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg) ### The Westin Poinsett Greenville 10/10 Excellent "Great hotel Great location Great room Friendly and courteous staff" [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Place is very" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Fairfield Inn by Marriott Greenville-Spartanburg Airport](https://images.trvl-media.com/lodging/1000000/70000/67800/67753/97563107_y.jpg) ### Fairfield Inn by Marriott Greenville-Spartanburg Airport 10/10 Excellent "Yes" [](https://expedia.ca/Greenville-Hotels-Fairfield-Inn-By-Marriott-Greenville-Spartanburg-Airport.h67753.Hotel-Information) ## Explore a world of travel with Expedia - 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