Title: Upstate South Carolina Villas from CA $2,615 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Upstate South Carolina Villa Rentals from CA $2,615 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=VILLA&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=VILLA&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=VILLA&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2026-01-23&endDate=2026-01-25&adults=2&lodging=VILLA&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Upstate South Carolina Villas ![Exterior](https://images.trvl-media.com/lodging/84000000/83930000/83926500/83926429/c28346eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/84000000/83930000/83926500/83926429/55f22ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/84000000/83930000/83926500/83926429/80dfba6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/84000000/83930000/83926500/83926429/fe288167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brand new construction Villa with high end modern amenities! Pickens 10/10 Exceptional (24) "It was just what we needed for our wknd stay!!! Thank you " [](https://www.expedia.ca/Pickens-Hotels-Brand-New-Construction-Villa-With-High-End-Modern-Amenities.h83926429.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106160000/106152200/106152144/eb525b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106160000/106152200/106152144/1f8c7893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/107000000/106160000/106152200/106152144/e73887b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/107000000/106160000/106152200/106152144/621ae95d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful villa on Lake Hartwell, stunning views, large deck for family to enjoy Anderson 9.8/10 Exceptional (8) "This is a very clean villa. The view is beautiful. If you have any questions, David is always available. We would definitely stay here again." [](https://www.expedia.ca/Anderson-Hotels-Beautiful-Family-Villa-With-Large-Deck.h106152144.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90800000/90798800/90798763/412bcbfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90800000/90798800/90798763/5f7d01f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90800000/90798800/90798763/53a6229c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90800000/90798800/90798763/37a4749f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marina Village 338 In Keowee Key Salem 8.0/10 Very good (2) "Nice get away enjoyed our stay! Will definitely recommend!" [](https://www.expedia.ca/Salem-Hotels-Marina-Village-338-In-Keowee-Key.h90798763.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49010000/49009000/49008902/c2d5eaa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/50000000/49010000/49009000/49008902/aecc55ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach towels](https://images.trvl-media.com/lodging/50000000/49010000/49009000/49008902/01ec73da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/50000000/49010000/49009000/49008902/a9cce60f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 queen beds comfy lake Keowee community, golf,hike,waterfalls, close to Clemson Salem 10/10 Exceptional (48) "Home was as advertised. Very nice stay!" [](https://www.expedia.ca/Salem-Hotels-Chalet-Style-2-Bedroom-Condo-In-A-Lake-Keowee-Community-Near-Clemson.h49008902.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/2766306d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/f2c1860f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/96d7fead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining tables](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/b71e7956.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Southern Elegance near Downtown Pickens Pickens CA $1,505 CA $2,615 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Pickens-Hotels-Grand-Southern-Elegance-Near-Downtown-Pickens.h91908503.Hotel-Information) ![Villa (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537601/9dccd7a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537601/1b44aa4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537601/f11f8223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537601/35ac8447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 Mi to Clemson: Central Villa w/ Deck, Near Lakes Clemson [](https://www.expedia.ca/Clemson-Hotels-Central-Villa-W-Game-Room-Deck-Near-Lakes.h93537601.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14®ionId=553248635975748552&adults=2&lodging=VILLA&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Villas.d553248635975748552-aaVillas.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Villas.d553248635975748552-aaVillas.Travel-Guide-Accommodation) ## Top Upstate South Carolina Hotel Reviews ![Hampton Inn & Suites Greenville Airport, SC](//images.trvl-media.com/lodging/12000000/11920000/11919200/11919192/de1bb5e2_y.jpg) ### Hampton Inn & Suites Greenville Airport, SC 10/10 Excellent "Check in was quick and easy, and the entire place was clean and tidy. The bed was very comfortable." [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Airport.h11919192.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Very Clean and staff was very polite." [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Comfort Suites Greenville Airport](//images.trvl-media.com/lodging/47000000/46120000/46116400/46116309/9d9a99c3_y.jpg) ### Comfort Suites Greenville Airport 10/10 Excellent "Clean comfortable room" [](https://expedia.ca/Greenville-Spartanburg-Hotels-Comfort-Suites.h46116309.Hotel-Information) ![Woodspring Suites Greenville Airport](//images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/69b6f44b_y.jpg) ### Woodspring Suites Greenville Airport 10/10 Excellent "Great location and very secure property" [](https://expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](//images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Everything! Beautiful, convenient and wonderful staff!" [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Nice easy walk to bon seCour center" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Great VALUE and great room. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Highly recommended Really good value for money " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Golf Clean rooms Staff was awesome Beautiful property " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ## Find out more about Upstate South Carolina ## Upstate South Carolina Villas information | Number of reviews | 79 | | --- | --- | | Accommodation | 6 Villas | | Lowest Price | CA $2,615 | | Highest Price | CA $2,615 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Anglewood Hotels](https://www.expedia.ca/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Cross Anchor Hotels](https://www.expedia.ca/Cross-Anchor-Hotels.d553248635519281641.Travel-Guide-Hotels) - [Cottages in Duncan](https://www.expedia.ca/Duncan-Cottages.d6761-aaCottages.Travel-Guide-Accommodation) - [Lodges in Duncan](https://www.expedia.ca/Duncan-Lodges.d6761-aaLodges.Travel-Guide-Accommodation) - [Aparthotels in Enoree](https://www.expedia.ca/Enoree-Apart-Hotels.d3000353124-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Enoree](https://www.expedia.ca/Enoree-Bed-And-Breakfast.d3000353124-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Enoree](https://www.expedia.ca/Enoree-Hotels-Cheap-Hotels.0-0-d3000353124-tCheapHotels.Travel-Guide-Filter-Hotels) - [Enoree Hotels](https://www.expedia.ca/Enoree-Hotels.d3000353124.Travel-Guide-Hotels) - [Aparthotels in Fingerville](https://www.expedia.ca/Fingerville-Apart-Hotels.d3000353129-aaApartHotels.Travel-Guide-Accommodation) - 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[Flights from Aiken (AIK) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/aik/spa/aiken-to-spartanburg) - [Flights from Atlanta (ATL) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/atl/spa/atlanta-to-spartanburg) - [Flights from Asheville (AVL) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/avl/spa/asheville-to-spartanburg) - [Flights from Bradford (BFD) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/bfd/spa/bradford-to-spartanburg) - [Flights from Battle Creek (BTL) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/btl/spa/battle-creek-to-spartanburg) - [Flights from Bowling Green (BWG) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/bwg/spa/bowling-green-to-spartanburg) - [Flights from North Myrtle Beach (CRE) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/cre/spa/north-myrtle-beach-to-spartanburg) - [Flights from Charleston (CRW) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/crw/spa/charleston-to-spartanburg) - [Flights from Washington (DCA) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/dca/spa/washington-to-spartanburg) - [Flights from Elmira (ELM) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/elm/spa/elmira-to-spartanburg) - [Flights from Fayetteville (FAY) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/fay/spa/fayetteville-to-spartanburg) - [Flights from Frederick (FDK) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/fdk/spa/frederick-to-spartanburg) - [Flights from Greenville (GSP) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/gsp/spa/greenville-to-spartanburg) - [Flights from New Haven (HVN) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/hvn/spa/new-haven-to-spartanburg) - [Flights from Niagara Falls (IAG) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/iag/spa/niagara-falls-to-spartanburg) - [Flights from Kinston (ISO) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/iso/spa/kinston-to-spartanburg) - [Flights from Manville (JVI) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/jvi/spa/manville-to-spartanburg) - [Flights from Macon (MCN) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/mcn/spa/macon-to-spartanburg) - 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