Title: Seneca Vacation Home Rentals from CA $227: Search Top Private Vacation Homes for Rent | Expedia.ca

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![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 24 - Apr 26](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Seneca vacation homes

![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/89ea8ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Clemson Cottage - 3.6 mi. to Memorial Stadium

[](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

Seneca

10/10

Exceptional

(15 reviews)

"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mandy H.

CA $246

CA $540 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/fbb953e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/a6445e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/891c0bf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/2d71c6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  bedroom available in my house in lovely Seneca. 5 miles from Clemson University

[](https://www.expedia.ca/Seneca-Hotels-Charming-1-Bedroom-House-In-Lovely-Seneca-5-Miles-From-Clemson-University.h125624500.Hotel-Information)

Seneca

CA $64

CA $116 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-Charming-1-Bedroom-House-In-Lovely-Seneca-5-Miles-From-Clemson-University.h125624500.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/9b29fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/bc9bfba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/8a811318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell

[](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

Seneca

10/10

Exceptional

(9 reviews)

"Very easy check in and check out. It had everything we needed including wonderful views at the dock. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lance A.

CA $334

CA $720 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/e2e2f98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

[](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

Seneca

8.8/10

Excellent

(5 reviews)

"Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alisa W.

CA $224

CA $402 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/735219a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/91ac5b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

[](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information)

Serenity Bay

9.8/10

Exceptional

(130 reviews)

"A wonderful stay! The house offered many different spaces and the lake access/dock was perfect!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

stacy s.

CA $512

CA $977 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/9e2b77c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/bd51a502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/d1bcfdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/a5e27533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

[](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information)

Downtown

10/10

Exceptional

(16 reviews)

"Great home base for a Clemson game. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen A.

CA $212

CA $458 total

includes taxes & fees

Apr 1 - Apr 2

[](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information)

![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/41018e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, printers](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/d0ce4a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/aad65738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/3ef9dbf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Johnsons Cove - Lakefront Retreat With EV Charger

[](https://www.expedia.ca/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger-Family-And-Pet-Friendly.h114843702.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca G.

CA $450

CA $1,084 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger-Family-And-Pet-Friendly.h114843702.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/fc891652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d37b415d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d33a6537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/f0fe695d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

[](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information)

Seneca

9.6/10

Exceptional

(8 reviews)

"Very accommodating host. Property is a great location and very clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig F.

CA $445

CA $948 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/8d32bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/fa054611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, table tennis](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/1692b12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

[](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

Seneca

10/10

Exceptional

(5 reviews)

"Great place with a lot close by"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aldor D.

CA $290

CA $431 total

includes taxes & fees

Mar 17 - Mar 18

[](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/c027128d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video games, foosball](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/1ece8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/84d2a4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/5ddade10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Big Golf House- 10 miles to Clemson

[](https://www.expedia.ca/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information)

Seneca

10/10

Exceptional

(2 reviews)

"Absolutely! Perfect space for our needs, so for accommodating for our family & pet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gennifer Q.

CA $424

CA $857 total

includes taxes & fees

Apr 1 - Apr 2

[](https://www.expedia.ca/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information)

![Smart TV, fireplace, books, printers](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/81095175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/22d8032f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/fc8eb4fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books, printers](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/28fd8c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brick House At Currahee

[](https://www.expedia.ca/Toccoa-Hotels-The-Brick-House-At-Currahee.h93152735.Hotel-Information)

Toccoa

9.8/10

Exceptional

(86 reviews)

"My husband and I had a great stay! The house was fantastic and great for a weekend trip! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel M.

CA $147

CA $311 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Toccoa-Hotels-The-Brick-House-At-Currahee.h93152735.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/23dbb562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/950291d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/ff2de438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/7d94b763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sunny Side Cottage: Cozy Stay by Anderson U!

[](https://www.expedia.ca/Anderson-Hotels-Charming-Bungalow-One-Block-To-Anderson-University.h100330565.Hotel-Information)

Anderson

9.8/10

Exceptional

(23 reviews)

"Great stay, home was well stocked with all the goodies that made the stay even more enjoyable!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin K.

CA $147

CA $527 total

includes taxes & fees

Mar 5 - Mar 6

[](https://www.expedia.ca/Anderson-Hotels-Charming-Bungalow-One-Block-To-Anderson-University.h100330565.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/125000000/124170000/124162600/124162529/e8b6e199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/125000000/124170000/124162600/124162529/66229e2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/125000000/124170000/124162600/124162529/17bad4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/125000000/124170000/124162600/124162529/bb572974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The sweetest Spot is your cozy and convenient Northeast, GA getaway,

[](https://www.expedia.ca/Toccoa-Hotels-The-Sweetest-Spot-Is-Your-Cozy-And-Convenient-Northeast.h124162529.Hotel-Information)

Toccoa

10/10

Exceptional

(2 reviews)

"Everything is good thanks"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

MariaIsabel

CA $60

CA $155 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Toccoa-Hotels-The-Sweetest-Spot-Is-Your-Cozy-And-Convenient-Northeast.h124162529.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/a31ec2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/b904fba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/64f187a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/8905f49d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake front with dock & covered slip on Lake Hartwell. The Reese Retreat!

[](https://www.expedia.ca/Westminster-Hotels-Lake-Front-With-Dock-Covered-Slip-On-Lake-Hartwell-The-Reese-Retreat.h113928424.Hotel-Information)

Westminster

8.6/10

Excellent

(8 reviews)

"Awesome lake house. Hope to stay again in the future at some point!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

steven r.

CA $172

CA $471 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Westminster-Hotels-Lake-Front-With-Dock-Covered-Slip-On-Lake-Hartwell-The-Reese-Retreat.h113928424.Hotel-Information)

![](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/4dfb8425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/ad6745d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/46d429c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/ee36db68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stylish | Pvt Baths | Minutes to Dining & Shopping

[](https://www.expedia.ca/Anderson-Hotels-Cozy-2-Bedroom-2-Bath-House-In-Anderson.h123391761.Hotel-Information)

Anderson

CA $174

CA $433 total

includes taxes & fees

Mar 24 - Mar 25

[](https://www.expedia.ca/Anderson-Hotels-Cozy-2-Bedroom-2-Bath-House-In-Anderson.h123391761.Hotel-Information)

![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/8dd3309b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/0ab2e017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/3600e2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/56576d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Apple Cottage

[](https://www.expedia.ca/Pickens-Hotels-Country-Apple-Cottage.h103157886.Hotel-Information)

Pickens

10/10

Exceptional

(33 reviews)

"Great place close to Clemson. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos V.

CA $109

CA $227 total

includes taxes & fees

Mar 4 - Mar 5

[](https://www.expedia.ca/Pickens-Hotels-Country-Apple-Cottage.h103157886.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/611292d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/f3b8854d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/13e2736c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/114000000/113520000/113518400/113518324/dfa77891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clemson University (6 min) - 1kMbps Internet - Easy Check In - Office Space

[](https://www.expedia.ca/Pendleton-Hotels-Charming-3-Bedroom-House-In-Pendleton-With-AC.h113518324.Hotel-Information)

Pendleton

10/10

Exceptional

(5 reviews)

"Good condition, easy access. Good location. Clean and good amenities."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alexander B.

CA $171

CA $554 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Pendleton-Hotels-Charming-3-Bedroom-House-In-Pendleton-With-AC.h113518324.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100780000/100778300/100778264/ecaeb70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100780000/100778300/100778264/w2046h1365x0y0-8224868a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100780000/100778300/100778264/w2047h1364x1y1-a5871079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100780000/100778300/100778264/w2047h1364x1y1-51c20fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury-Family Friendly-Game Room-Huge Porch-Comfortable/Beautiful Beds

[](https://www.expedia.ca/Highlands-Hotels-Luxury-Family-Friendly-Game-Room-Huge-Porch-ComfortableBeautiful-Beds.h100778264.Hotel-Information)

Highlands

10/10

Exceptional

(17 reviews)

"Great comfort and location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dena H.

CA $199

CA $735 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Highlands-Hotels-Luxury-Family-Friendly-Game-Room-Huge-Porch-ComfortableBeautiful-Beds.h100778264.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/b7a1f289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, foosball, books](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/d57b249b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/7411cba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/df53fc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Welcome To Downtown Pickens close to Clemson and Lake Keowee

[](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information)

Pickens

9.8/10

Exceptional

(32 reviews)

"Great location, close to great restaurants and downtown. Beautiful area!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tom B.

CA $147

CA $359 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/b3b4e7a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/0bba5ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/7f158818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/d9700a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clemson|LakeAccess|ParkPass|PizzaOven|YouTubeTV|King|SUPs|EV

[](https://www.expedia.ca/Anderson-Hotels-ClemsonMarinaParkPassPizzaOvenKayaksFirePit.h109017166.Hotel-Information)

Anderson

10/10

Exceptional

(8 reviews)

"Stefania was more than helpful! We will definitely book with her again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anna S.

CA $216

CA $670 total

includes taxes & fees

Mar 11 - Mar 12

[](https://www.expedia.ca/Anderson-Hotels-ClemsonMarinaParkPassPizzaOvenKayaksFirePit.h109017166.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

Cabins

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Cottages

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Private vacation homes

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Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=APARTMENT)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=CONDO)

Aparthotels

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Villas

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=VILLA)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=HOUSE_BOAT)

Chalets

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=CHALET)

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## Top Seneca Hotel Reviews

![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg)

### Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent

"Great having a washer and dry available and the breakfast staff was amazing and very nice."

[](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information)

![Fairfield Inn & Suites Seneca Clemson Univ Area    ](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894_y.jpg)

### Fairfield Inn & Suites Seneca Clemson Univ Area 

10/10 Excellent

"Very good "

[](https://expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff_y.jpg)

### Lakeside Lodge Clemson

10/10 Excellent

"Clean room, great service!"

[](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg)

### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"it smelled good and it was clean "

[](https://expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg)

### Quality Inn Seneca Clemson Area US-123

10/10 Excellent

"All great"

[](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8_y.jpg)

### Tru by Hilton Seneca Clemson

10/10 Excellent

"Always clean and friendly! "

[](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

![New to VRBO! Big water views, private dock, pool table, 15 min Clemson!](https://images.trvl-media.com/lodging/58000000/57950000/57941100/57941024/fbdc7d33_y.jpg)

### New to VRBO! Big water views, private dock, pool table, 15 min Clemson!

10/10 Excellent

"Fabulous house - big water views!New home - beautiful bathrooms & kitchen.Well equipped kitchen - lots of space - wonderful outdoor lounge areas.Host very helpful.Will definitely book a return visit!"

[](https://expedia.ca/Anderson-Hotels-Large.h57941024.Hotel-Information)

![Perfect Lake Hartwell Getaway - Gorgeous Lake Views!](https://images.trvl-media.com/lodging/38000000/37750000/37749500/37749425/391b1689_y.jpg)

### Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

10/10 Excellent

"Host was very responsive. House was clean. Would stay here again. "

[](https://expedia.ca/Anderson-Hotels-Perfect-Lake-Hartwell-Getaway-Gorgeous-Lake-Views.h37749425.Hotel-Information)

![Best Western Seneca-Clemson](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0_y.jpg)

### Best Western Seneca-Clemson

10/10 Excellent

"Customer Service is always great. Always have a good variety of breakfast. "

[](https://expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information)

## Find out more about Seneca

## Seneca Vacation Homes information

| Number of reviews | 384                |
| ----------------- | ------------------ |
| Accommodation     | 659 Vacation Homes |
| Lowest Price      | CA $227            |
| Highest Price     | CA $1,084          |

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- [Flights to Clemson ](https://www.expedia.ca/Cheap-Flights-To-Clemson.d6594.Travel-Guide-Flights)
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- [Central Vacations ](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides)
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- [Visit Townville ](https://www.expedia.ca/Townville.dx3000456148)

- [Car rental Central ](https://www.expedia.ca/Car-Rentals-In-Central.d10503.Car-Rental-Guide)
- [Car rental Clemson ](https://www.expedia.ca/Car-Rentals-In-Clemson.d6594.Car-Rental-Guide)
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- [Walhalla Vacation Rentals ](https://www.expedia.ca/Walhalla-Vacation-Rentals.d170696.Travel-Guide-VacationRentals)

- [Book Vacation Homes in Seneca on Expedia.com ](https://www.expedia.com/Seneca-Private-Vacation-Homes.d6548-aaPrivateVacationHomes.Travel-Guide-Accommodation)