Title: Seneca Vacation Rentals from CA $212: Short-Term Rentals for 2026 | Expedia.ca

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![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 26 - Jun 28](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 24 - Jul 26](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Seneca vacation rentals

![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/2da98b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/ec2a8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

[](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

Seneca

9.8/10

Exceptional

(66 reviews)

"Excellent stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beonca

CA $137

CA $212 total

includes taxes & fees

Apr 6 - Apr 7

[](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c0b82041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/b1844261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c2f5c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/5fc6414e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Enjoy one of our RV units son less of a headache for you this vacation!

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information)

Seneca

8.0/10

Very good

(4 reviews)

"My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise s.

CA $106

CA $224 total

includes taxes & fees

Apr 14 - Apr 15

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information)

![Smart TV, video games, table tennis](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/eea5ec7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/5f42512b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/86d085c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/c53fb178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

[](https://www.expedia.ca/Seneca-Hotels-Lakeside-Clemson-Condo-With-4KSurround-SoundXboxCoffee-BarPrivate-Bathrooms.h97053582.Hotel-Information)

Seneca

10/10

Exceptional

(21 reviews)

"Very nice accommodations and great location for stay in Clemson. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marisa G.

CA $164

CA $511 total

includes taxes & fees

Apr 15 - Apr 16

[](https://www.expedia.ca/Seneca-Hotels-Lakeside-Clemson-Condo-With-4KSurround-SoundXboxCoffee-BarPrivate-Bathrooms.h97053582.Hotel-Information)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/9e2b77c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/d1bcfdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/651434b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/bd51a502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

[](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information)

Downtown

10/10

Exceptional

(16 reviews)

"Great home base for a Clemson game. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen A.

CA $194

CA $439 total

includes taxes & fees

Apr 6 - Apr 7

[](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/w1536h2048x0y0-6998e207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/ad885ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/405dd7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/c9812bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Clemson TIny House Cabin

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information)

Seneca

CA $173

CA $305 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/45872750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Clemson Cottage - 3.6 mi. to Memorial Stadium

[](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

Seneca

10/10

Exceptional

(16 reviews)

"Seriously comfortable home, the beds and pillows all fantastic, nicely appointed in every way. Can’t wait to stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

[](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/67979a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/424e1883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/c5a2afe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/e2588273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information)

Seneca

10/10

Exceptional

(12 reviews)

"Very clean and comfortable - very close to Clemson and easy access. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jim A.

CA $208

CA $279 total

includes taxes & fees

Apr 6 - Apr 7

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/fa054611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/8d32bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, table tennis](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/1692b12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

[](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

Seneca

10/10

Exceptional

(6 reviews)

"Great place with a lot close by"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aldor D.

CA $348

CA $543 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/9b29fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/518d0c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/8a811318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell

[](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

Seneca

10/10

Exceptional

(9 reviews)

"We enjoyed our stay. Had everything we needed. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Diane S.

CA $340

CA $733 total

includes taxes & fees

Apr 15 - Apr 16

[](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/39da46e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/482da2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video library](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/ff6eb6d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/d6399ba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Cottage Retreat-12 Minutes from Clemson University

[](https://www.expedia.ca/Seneca-Hotels-Carolina-Cottage-Retreat.h126982607.Hotel-Information)

Seneca

CA $219

CA $437 total

includes taxes & fees

Apr 30 - May 1

[](https://www.expedia.ca/Seneca-Hotels-Carolina-Cottage-Retreat.h126982607.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/f084865a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/20842dc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/9bb2205c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/686661ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

[](https://www.expedia.ca/Seneca-Hotels-A-Cozy-Family-Home-With-A-Relaxing-Stay-In-A-Quiet-Setting.h127013757.Hotel-Information)

Seneca

CA $228

CA $448 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Seneca-Hotels-A-Cozy-Family-Home-With-A-Relaxing-Stay-In-A-Quiet-Setting.h127013757.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/47000000/46570000/46561400/46561363/07839e6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/47000000/46570000/46561400/46561363/3efe6b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player, books](https://images.trvl-media.com/lodging/47000000/46570000/46561400/46561363/90-0580d73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sun loungers, beach towels](https://images.trvl-media.com/lodging/47000000/46570000/46561400/46561363/2f3bdd1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakefront home with private beach & unbelievable sunsets on Lake Keowee

[](https://www.expedia.ca/Asheville-Hotels-Vrbo-Property.h46561363.Hotel-Information)

Seneca

10/10

Exceptional

(81 reviews)

"Perfect place for a gameday weekend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maggie B.

CA $468

CA $903 total

includes taxes & fees

Apr 8 - Apr 9

[](https://www.expedia.ca/Asheville-Hotels-Vrbo-Property.h46561363.Hotel-Information)

![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/5388a21f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/bea2ca6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/db481623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/2ad3fd14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Seneca Home - 3 Mi to Memorial Stadium!

[](https://www.expedia.ca/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information)

Seneca

[](https://www.expedia.ca/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/51bdec15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

[](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

Seneca

8.8/10

Excellent

(5 reviews)

"Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alisa W.

CA $228

CA $409 total

includes taxes & fees

Apr 8 - Apr 9

[](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/41018e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/3ef9dbf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, printers](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/d0ce4a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/aad65738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Johnsons Cove - Lakefront Retreat With EV Charger

[](https://www.expedia.ca/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger.h114843702.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca G.

CA $534

CA $1,157 total

includes taxes & fees

Apr 15 - Apr 16

[](https://www.expedia.ca/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger.h114843702.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/c027128d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video games, foosball](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/1ece8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/9e13146e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/84d2a4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Big Golf House- 10 miles to Clemson

[](https://www.expedia.ca/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information)

Seneca

10/10

Exceptional

(2 reviews)

"Absolutely! Perfect space for our needs, so for accommodating for our family & pet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gennifer Q.

CA $329

CA $752 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/fc891652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d33a6537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/f0fe695d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/98c8974f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

[](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information)

Seneca

9.6/10

Exceptional

(8 reviews)

"Very accommodating host. Property is a great location and very clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig F.

CA $454

CA $967 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/b866198b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player, table tennis, books](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/c4de2bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/c09b9ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/3e3661cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Keowee Retreat! Swim, Boat, Kayak & Relax on Dock Just Steps from the Water

[](https://www.expedia.ca/Seneca-Hotels-LAKE-FRONT-RETREAT-Steps-Away-From-Swimming.h37012874.Hotel-Information)

Seneca

10/10

Exceptional

(82 reviews)

"Nice location and functionality for family. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

T P.

CA $725

CA $1,260 total

includes taxes & fees

Apr 15 - Apr 16

[](https://www.expedia.ca/Seneca-Hotels-LAKE-FRONT-RETREAT-Steps-Away-From-Swimming.h37012874.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/735219a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/644a4539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

[](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information)

Serenity Bay

9.8/10

Exceptional

(130 reviews)

"Beautiful home, well furnished, very clean, easy TV"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

CA $396

CA $836 total

includes taxes & fees

Apr 6 - Apr 7

[](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information)

![Cabin, 2 Bedrooms, Non Smoking (No Pets, Linens Included) | In-room dining](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/e62d89db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 2 Bedrooms, Non Smoking (No Pets, Linens Included) | Living room](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/1853a44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/44e61f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/6f5c7f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Landing RV Resort - Caravan Park

[](https://www.expedia.ca/Fair-Play-Hotels-Carolina-Landing-RV-Resort-Caravan-Park.h9126575.Hotel-Information)

Fair Play

7.6/10

Good

(47 reviews)

"Lake "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Milton

CA $180

CA $198 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Fair-Play-Hotels-Carolina-Landing-RV-Resort-Caravan-Park.h9126575.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-16&endDate=2026-04-17&regionId=6548&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=CABIN)

Cottages

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Private vacation homes

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Condos

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=CONDO)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=APART_HOTEL)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=VILLA)

Chalets

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=CHALET)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=HOUSE_BOAT)

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## Top Seneca Hotel Reviews

![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283_y.jpg)

### Tru by Hilton Seneca Clemson

10/10 Excellent

"My first time staying there and I was very impressed. From the staff to the cleanliness everything was great. Highly recommend and will be my place to stay every time I come in town."

[](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg)

### Best Western Plus Clemson Hotel & Conference Center

6/10 Okay

"Dirty hallways; terrible gym facilities."

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/8f736b3a_y.jpg)

### Hampton Inn & Suites Seneca-Clemson Area

8/10 Good

"The two desk clerk we interacted with were extra cheerful and very helpful. The breakfast was very good, as expected. The room was perfectly clean and fresh. Good beds, okay location, fairly priced. Would return again. "

[](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information)

![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90_y.jpg)

### Lakeside Lodge Clemson

2/10 Terrible

"I must have gotten the absolute worst room here. The last time I stayed I had a great room with a balcony. This time, I got a "patio," that I even paid extra for that connected to the parking lot overlooking the highway on the fist floor. The room smelled AWFUL. Then I realized it must have been a pet room. Smelled like dog urine and the front desk said they couldn't move me because I had booked through Expedia. They offered to spray the room. With what, I have no idea. Probably some kind of dog urine spray reducer. Gross. Very disappointed. "

[](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

![Days Inn by Wyndham Seneca / Clemson Area](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce_y.jpg)

### Days Inn by Wyndham Seneca / Clemson Area

6/10 Okay

"Clean room"

[](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information)

![The HART of Tiger Town!  Lakefront home less than 4 miles to Clemson University](https://images.trvl-media.com/lodging/108000000/107260000/107251800/107251774/35048b01_y.jpg)

### The HART of Tiger Town! Lakefront home less than 4 miles to Clemson University

10/10 Excellent

"Plenty of room, love the backyard for the kids and comfortable beds!"

[](https://expedia.ca/Seneca-Hotels-The-HART-Of-Tiger-Town-Lakefront-Home-Less-Than-4-Miles-To-Clemson-University.h107251774.Hotel-Information)

![4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit,  Pet Friendly!](https://images.trvl-media.com/lodging/34000000/33730000/33728200/33728167/7de7c272_y.jpg)

### 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

10/10 Excellent

"Wonderful stay, fully equipped, beautiful lake property, would stay there again, affordable for a great experience "

[](https://expedia.ca/Anderson-Hotels-Beautiful-43.h33728167.Hotel-Information)

![New to VRBO! Big water views, private dock, pool table, 15 min Clemson!](https://images.trvl-media.com/lodging/58000000/57950000/57941100/57941024/eb68ea9e_y.jpg)

### New to VRBO! Big water views, private dock, pool table, 15 min Clemson!

10/10 Excellent

"We enjoyed our stay at your property very much.Everything was exceptionally clean and well taken care of. Thank you for quickly addressing the issue with the heat pump."

[](https://expedia.ca/Anderson-Hotels-Large.h57941024.Hotel-Information)

![Best Western Seneca-Clemson](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a_y.jpg)

### Best Western Seneca-Clemson

10/10 Excellent

"Clean room! Great staff! "

[](https://expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information)

## Find out more about Seneca

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Seneca. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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- [Vacation Homes in Seneca ](https://expedia.ca/Seneca-Private-Vacation-Homes.d6548-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cottages in Seneca ](https://expedia.ca/Seneca-Cottages.d6548-aaCottages.Travel-Guide-Accommodation)
- [Cabin Rentals in Seneca ](https://expedia.ca/Seneca-Cabins.d6548-aaCabins.Travel-Guide-Accommodation)
- [Apartments in Seneca ](https://expedia.ca/Seneca-Apartments.d6548-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Seneca ](https://expedia.ca/Seneca-Condos.d6548-aaCondos.Travel-Guide-Accommodation)
- [Villas in Seneca ](https://expedia.ca/Seneca-Villas.d6548-aaVillas.Travel-Guide-Accommodation)
- [Motels in Seneca ](https://expedia.ca/Seneca-Motels.d6548-aaMotels.Travel-Guide-Accommodation)
- [Farmstay in Seneca ](https://expedia.ca/Seneca-Agritourism.d6548-aaAgritourism.Travel-Guide-Accommodation)
- [Lodges in Seneca ](https://expedia.ca/Seneca-Lodges.d6548-aaLodges.Travel-Guide-Accommodation)
- [RV Parks in Seneca ](https://expedia.ca/Seneca-RV-Parks.d6548-aaRVParks.Travel-Guide-Accommodation)
- [B&B in Seneca ](https://expedia.ca/Seneca-Bed-And-Breakfast.d6548-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Guest Houses in Seneca ](https://expedia.ca/Seneca-Guest-Houses.d6548-aaGuestHouses.Travel-Guide-Accommodation)
- [Chalets in Seneca ](https://expedia.ca/Seneca-Chalets.d6548-aaChalets.Travel-Guide-Accommodation)
- [Houseboats in Seneca ](https://expedia.ca/Seneca-Houseboats.d6548-aaHouseboats.Travel-Guide-Accommodation)
- [Aparthotels in Seneca ](https://expedia.ca/Seneca-Apart-Hotels.d6548-aaApartHotels.Travel-Guide-Accommodation)
- [Condo Resorts in Seneca ](https://expedia.ca/Seneca-Condominium-Resort.d6548-aaCondominiumResort.Travel-Guide-Accommodation)

## Frequently asked questions

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