A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacation Rentals

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Our top choices for Upstate South Carolina vacation rentals

1. Adorable Upscale cottage in Downtown Fountain Inn.

Adorable Upscale cottage in Downtown Fountain Inn.
Fountain Inn
10.0 out of 10, Exceptional, (45 reviews)
"It was a great location for us as we're building in Fountain Inn. Very cute, very comfortable, close to everything we needed. Host was great. Will stay again"
United States
Valerie
The price is CA $184
CA $382 total
includes taxes & fees
Oct 15 - Oct 16
Adorable Upscale cottage in Downtown Fountain Inn.

2. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (107 reviews)
"Me and my family had a great time"
United States
Nirumol
The price is CA $143
CA $220 total
includes taxes & fees
Oct 29 - Oct 30
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

3. Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
The price is CA $147
CA $281 total
includes taxes & fees
Oct 11 - Oct 12
Carolina Camp Cedar

4. Charming luxury cottage in the heart of Boiling Springs

Charming luxury cottage in the heart of Boiling Springs
Boiling Springs
9.0 out of 10, Wonderful, (18 reviews)
"Very nice guest house. Property was clean and the host was very responsive to our questions. Lots of natural shade in the deck area. Would stay here again."
United States
Pat L.
The price is CA $135
CA $301 total
includes taxes & fees
Oct 4 - Oct 5
Charming luxury cottage in the heart of Boiling Springs

5. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (109 reviews)
"Fully equipped, comfortable beds…everything to make for an enjoyable stay. "
United States
Ron E.
The price is CA $115
CA $329 total
includes taxes & fees
Oct 6 - Oct 7
The Blue Bungalow by Unity Park - Newly Renovated

6. Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!

Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!
Roebuck
10.0 out of 10, Exceptional, (44 reviews)
"Awesome farmhouse, will stay here again on future trips!"
United States
Jeremy C.
The price is CA $250
CA $426 total
includes taxes & fees
Oct 6 - Oct 7
Whiffletree Farmhouse just 2 mins off I-26 & 8 mins from downtown Spartanburg!

7. ~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~
Spartanburg
10.0 out of 10, Exceptional, (57 reviews)
"Nice property, well stocked and quiet."
United States
sarah p.
The price is CA $142
CA $321 total
includes taxes & fees
Oct 18 - Oct 19
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

8. Southern Charm Townhome

Southern Charm Townhome
Simpsonville
10.0 out of 10, Exceptional, (11 reviews)
"Very clean and safe location. Super cute interior decorations and comfortable. Also a great location for us to visit family who are local. Absolutely would stay again."
United States
Brianna F.
Southern Charm Townhome

9. Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville
Greenville
9.6 out of 10, Exceptional, (21 reviews)
"The cabin was beautiful."
United States
John A.
The price is CA $116
CA $221 total
includes taxes & fees
Oct 1 - Oct 2
Historic 19th Century Cabin in Greenville

10. Secluded Tiny Home in Exclusive Paris Mountain!

Secluded Tiny Home in Exclusive Paris Mountain!
Greenville
10.0 out of 10, Exceptional, (14 reviews)
"Great location, quiet and perfect for a couple stay. "
United States
craig d.
The price is CA $132
CA $234 total
includes taxes & fees
Oct 8 - Oct 9
Secluded Tiny Home in Exclusive Paris Mountain!

11. 2 Queen Beds Non-Smoking

2 Queen Beds Non-Smoking
Greenville SC
10.0 out of 10, Exceptional, (86 reviews)
"Quiet atmosphere throughout the stay made it relaxing."
United States
Anonymous traveller
The price is CA $86
CA $104 total
includes taxes & fees
Oct 1 - Oct 2
2 Queen Beds Non-Smoking

12. stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall
3.0 star property
Greenville
9.2 out of 10, Wonderful, (232 reviews)
"Everything was great"
United States
Bentrez
The price is CA $169
CA $186 total
includes taxes & fees
Oct 1 - Oct 2
stayAPT Suites Greenville-Haywood Mall

13. Cozy 1BR Close to Downtown & Greenville Drive Baseball

Cozy 1BR Close to Downtown & Greenville Drive Baseball
Greenville
9.2 out of 10, Wonderful, (32 reviews)
"Good location, great communication"
United States
isaiah
The price is CA $66
CA $216 total
includes taxes & fees
Oct 4 - Oct 5
Cozy 1BR Close to Downtown & Greenville Drive Baseball

14. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Greenville
9.4 out of 10, Exceptional, (41 reviews)
"We had a great stay- the location was close to everything & very clean "
United States
Anonymous traveller
The price is CA $79
CA $265 total
includes taxes & fees
Oct 8 - Oct 9
2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

15. 2BR 2Bath - Swamp Rabbit Trail Resort

2BR 2Bath - Swamp Rabbit Trail Resort
Greenville
9.2 out of 10, Wonderful, (43 reviews)
"Great place right by the swamp, rabbit, grocery and trail. The place was clean as a whistle, and we really appreciated the amenities. We would one hundred percent stay there again."
United States
Robyn L.
The price is CA $80
CA $265 total
includes taxes & fees
Oct 4 - Oct 5
2BR 2Bath - Swamp Rabbit Trail Resort

16. Walk to Bridgeway Station! Home w/ Pool Access

Walk to Bridgeway Station! Home w/ Pool Access
3.0 star property
Greenville
The price is CA $204
CA $644 total
includes taxes & fees
Oct 18 - Oct 19
Walk to Bridgeway Station! Home w/ Pool Access

17. Bright & Cozy 2BR Apt w/ Parking

Bright & Cozy 2BR Apt w/ Parking
Greenville
10.0 out of 10, Exceptional, (13 reviews)
"Excellent stay—spotless room, awesome staff, and great amenities."
United States
Crystal
Bright & Cozy 2BR Apt w/ Parking

18. GORGEOUS 1 BR on MAIN #2

GORGEOUS 1 BR on MAIN #2
Greenville Downtown
9.8 out of 10, Exceptional, (27 reviews)
"Looks better than the photos, great location. Comfy bed. We didn’t cook, but would have had all needed cookware. Appreciate the sound machine and extra clean linens. "
United States
Nikki P.
The price is CA $214
CA $392 total
includes taxes & fees
Oct 4 - Oct 5
GORGEOUS 1 BR on MAIN #2

19. Chic Downtown 2BR Condo walk to The Well Arena

Chic Downtown 2BR Condo walk to The Well Arena
Greenville Downtown
9.8 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay! "
United States
Finney G.
The price is CA $179
CA $412 total
includes taxes & fees
Oct 20 - Oct 21
Chic Downtown 2BR Condo walk to The Well Arena

20. Peaceful Oasis Convenient to Greenville!

Peaceful Oasis Convenient to Greenville!
Simpsonville
10.0 out of 10, Exceptional, (115 reviews)
"Pet friendly"
United States
Debra C.
Peaceful Oasis Convenient to Greenville!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Find out more about Upstate South Carolina

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Upstate South Carolina. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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