Central Vacation Home Rentals from CA $269: Search Top Private Vacation Homes for Rent

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Our top choices for Central vacation homes

A cozy living room with a fireplace, a dining area with a table and chairs, and a kitchen in the background.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the text "stay awhile".

A bedroom with a bed, bedside tables, a lamp, a wooden floor, a door, and a small table with a plant.

A two-story house with a porch, a number '209' on the front, and a small garden with shrubs and a pathway.

1. Clemson Memorabilia House Frank Howard III’s Home

Clemson Memorabilia House Frank Howard III’s Home

Clemson

8.4 out of 10, Very good, (20 reviews)

8.4/10

Very good

(20 reviews)

"Great location!"

Libby S.

The price is CA $116

CA $116

CA $366 total

includes taxes & fees

Sep 7 - Sep 8

Clemson Memorabilia House Frank Howard III’s Home

A church interior with pews, a cross, and a view of a landscape through a large window.

A narrow hallway with wooden flooring, a ceiling fan, and a door leading to a room with a computer and shelves.

A narrow hallway with a wooden floor leading to a kitchen area with a microwave and a sign that reads "Jon Appetit."

A narrow hallway with wooden flooring, a striped rug, and a stack of white towels on a wooden rack.

2. The Rustic Rectangle

The Rustic Rectangle

Pendleton

10.0 out of 10, Exceptional, (12 reviews)

10/10

Exceptional

(12 reviews)

"Great fun experiencing a shipping container conversion!"

Mary Ellen V.

The price is CA $134

CA $134

CA $334 total

includes taxes & fees

Sep 8 - Sep 9

The Rustic Rectangle

A spacious living room with a sofa, chairs, a wooden coffee table, and a fireplace.

A two-story house with a covered porch and a flag.

A bedroom with a wooden wardrobe, a bed, and a kitchen visible through an open door.

A spacious living area with a large sofa, a wooden coffee table, and a dining area with a table and chairs. A kitchen is visible in the background.

3. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Seneca

8.0 out of 10, Very good, (7 reviews)

8.0/10

Very good

(7 reviews)

"Adorable and clean house! The yard is beautiful "

Diana H.

The price is CA $226

CA $226

CA $404 total

includes taxes & fees

Sep 27 - Sep 28

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

A dining area with a wooden table, chairs, and a hanging light fixture.

A bedroom with a bed, a nightstand, a lamp, a mirror, and a rug.

A brick house with a porch, a door leading to the interior, and a mailbox.

A kitchen with wooden cabinets, a white refrigerator, a stainless steel sink, and a potted plant.

4. Iroquois Crossroads - 10 min from Clemson & lakes

Iroquois Crossroads - 10 min from Clemson & lakes

Seneca

The price is CA $161

CA $161

CA $458 total

includes taxes & fees

Sep 9 - Sep 10

Iroquois Crossroads - 10 min from Clemson & lakes

A kitchen with white cabinets, a stainless steel refrigerator, and a countertop with a flower arrangement and a bag.

A two-story building with a balcony, a garage, and a staircase.

A bedroom with a bed, a desk, a chair, a TV, and a ceiling fan.

A dining area with a wooden table set for four, surrounded by chairs, in a room with hardwood flooring and white walls.

5. Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!

Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!

Clemson

The price is CA $270

CA $270

CA $664 total

includes taxes & fees

Sep 29 - Sep 30

Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!

A living room with a sofa, coffee table, TV, and a ceiling fan.

A kitchen with white cabinets, a black refrigerator, a stove, a microwave, and a window with blinds.

A brick house with a covered porch, two chairs, and a small table.

A bedroom with a bed, bedside tables, a window with curtains, and wall-mounted artwork.

6. Charming 2-Bd 1-Ba home in Easley near GVL & Clemson w/WiFi, self check-in & AC

Charming 2-Bd 1-Ba home in Easley near GVL & Clemson w/WiFi, self check-in & AC

Easley

10.0 out of 10, Exceptional, (4 reviews)

10/10

Exceptional

(4 reviews)

"This was a cute spot for a sisters' weekend getaway. We had a lovely stay. The host was very responsive and so friendly, an absolute pleasure to work with! We would definitely stay again."

Michelle M.

The price is CA $130

CA $130

CA $317 total

includes taxes & fees

Sep 7 - Sep 8

Charming 2-Bd 1-Ba home in Easley near GVL & Clemson w/WiFi, self check-in & AC

A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.

A spacious dining area with a wooden table and chairs, a large rug, and a view of the kitchen and outdoor area.

A two-story house with a covered porch and a front yard.

A backyard with a fire pit, four Adirondack chairs, a wooden shed, and a small wooden structure with a smiley face.

7. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson

4.0 star property

Anderson

The price is CA $255

CA $255

CA $513 total

includes taxes & fees

Sep 20 - Sep 21

Lake Hartwell Frank Howard Home Clemson

A covered patio with a brick wall, a large tree, a wicker sofa, a metal chair, and a tiled floor.

A kitchen with wooden cabinets, a dishwasher, a refrigerator, and a window providing natural light.

A residential property with a paved driveway, a lawn, and a tree in the foreground.

A two-story brick house with a front porch, a central door, and a small front yard with a pathway leading to the entrance.

8. Welcome To Downtown Pickens close to Clemson and Lake Keowee

Welcome To Downtown Pickens close to Clemson and Lake Keowee

Pickens

9.8 out of 10, Exceptional, (40 reviews)

9.8/10

Exceptional

(40 reviews)

"Nice home. Loved the hardwood floors and the beautiful craftsmanship of the front door. Very impressive trees in the front yard."

Ross A.

The price is CA $149

CA $149

CA $361 total

includes taxes & fees

Sep 7 - Sep 8

Welcome To Downtown Pickens close to Clemson and Lake Keowee

A bedroom with a bed, a dresser, a nightstand, a lamp, and a painting on the wall.

A covered porch with white wooden railings and chairs, large windows, and a view of a house and greenery.

A modern kitchen with white cabinets, stainless steel appliances, and a granite countertop.

A kitchen with a granite countertop, stainless steel faucet, and a potted plant.

9. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson

Seneca

10.0 out of 10, Exceptional, (2 reviews)

10/10

Exceptional

(2 reviews)

"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."

Brenda B.

The price is CA $203

CA $203

CA $462 total

includes taxes & fees

Sep 23 - Sep 24

Renovated 3BR near Lake Keowee & Clemson

A covered porch with a blue door, a welcome mat, and a wooden deck.

A living room with a flat-screen TV, a coffee table, and a dining area with two stools.

A kitchen with granite countertops, wooden cabinets, a stainless steel range, and a built-in dishwasher.

A single-story house with a porch, a fenced yard, and a clear sky.

10. Charming 2-bedroom house in Clemson 4mi. from Death Valley and 1mi. from Mac's

Charming 2-bedroom house in Clemson 4mi. from Death Valley and 1mi. from Mac's

Clemson

10.0 out of 10, Exceptional, (4 reviews)

10/10

Exceptional

(4 reviews)

"It was a cute house in a quiet area, but easy to get to campus . It has a nice kitchen and even a porch with an eating area overlooking the big back yard"

Katherine

The price is CA $588

CA $588

CA $994 total

includes taxes & fees

Sep 9 - Sep 10

Charming 2-bedroom house in Clemson 4mi. from Death Valley and 1mi. from Mac's

A modern kitchen with white cabinets, granite countertops, and a central island. There is a dining area with a wooden table and white chairs.

A modern living room with a fireplace, a large TV, and a sofa set.

A two-story residential house with a garage, a small front yard, and a tree.

A bedroom with a large bed, a dresser, and a flat-screen TV on a stand.

11. Clemson University (6 min) - 1kMbps Internet - Easy Check In - Office Space

Clemson University (6 min) - 1kMbps Internet - Easy Check In - Office Space

Pendleton

10.0 out of 10, Exceptional, (6 reviews)

10/10

Exceptional

(6 reviews)

"Good condition, easy access. Good location. Clean and good amenities."

Alexander B.

The price is CA $142

CA $142

CA $522 total

includes taxes & fees

Sep 7 - Sep 8

Clemson University (6 min) - 1kMbps Internet - Easy Check In - Office Space

A modern kitchen with a central island, wooden cabinets, and a built-in refrigerator.

A modern living room with a sofa set, a coffee table, and a painting on the wall.

A wooden deck with railings, surrounded by trees and greenery.

A modern living room with a grey sofa, ottoman, and wooden flooring.

12. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Seneca

9.8 out of 10, Exceptional, (12 reviews)

9.8/10

Exceptional

(12 reviews)

"Easy check in, pet-friendly, great location!!"

Jason M.

The price is CA $292

CA $292

CA $506 total

includes taxes & fees

Sep 7 - Sep 8

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

A bedroom with a wooden bed, a ceiling fan, a painting of swans, and a television on a dresser.

A kitchen with wooden cabinets, a stainless steel microwave, a stove, and granite countertops.

An aerial view of a house surrounded by a well-maintained lawn and dense trees.

An outdoor patio with a wood-burning stove, seating, and a view of a forest.

13. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Seneca

The price is CA $200

CA $200

CA $558 total

includes taxes & fees

Sep 9 - Sep 10

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

A two-story house with a balcony, wooden deck, and string lights.

A modern living room with white furniture, a large window with a view, and decorative wall art.

A waterfront building with a balcony, a lawn, and a view of boats.

An outdoor seating area with tables and chairs, covered by umbrellas, and a website address displayed.

14. Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV

Anderson

10.0 out of 10, Exceptional, (12 reviews)

10/10

Exceptional

(12 reviews)

"Beautifully decorated and updated condo. It was so private it felt like a single home. Very thoughtful details throughout from the decor to the house supplies. We stayed to move my daughter into Clemson so didn’t take advantage of the lake or boards but there is a nice outdoor deck and even a fire pit. Very comfy vibe! About 15 to 20 minutes from campus, easy to get around."

Diana

The price is CA $207

CA $207

CA $658 total

includes taxes & fees

Sep 23 - Sep 24

An aerial view of a marina with multiple docks, a swimming pool, and a building with a dock extending into the water.

A swimming pool with lounge chairs and a parking lot.

Two white metal lounge chairs facing a lake with a view of trees and buildings in the distance.

A bar area with a marble countertop, multiple bar stools, and a television screen.

15. Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Salem

9.8 out of 10, Exceptional, (58 reviews)

9.8/10

Exceptional

(58 reviews)

"Awesome property for stay in the Keowee Key community. "

John G.

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

A covered porch with wicker furniture, a wooden table, and a ceiling fan.

A modern living room with a grey sofa set, a round coffee table, and a flat-screen TV.

A dining area with a round table, white chairs, and a hanging light fixture.

A bedroom with a bed, a chair, a TV, and a ceiling fan.

16. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Seneca

9.6 out of 10, Exceptional, (11 reviews)

9.6/10

Exceptional

(11 reviews)

"Everything was lovely."

Allison C.

The price is CA $485

CA $485

CA $986 total

includes taxes & fees

Sep 9 - Sep 10

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

A covered outdoor seating area with a table and chairs, large windows, and a ceiling fan.

A living room with a beige sofa, a glass coffee table, a patterned rug, a bookshelf, and a television.

A rustic cabin with a wooden door and windows, surrounded by a forested area.

A hallway with a wooden floor, a chandelier, and a door with a black frame.

17. Charming 2-bedroom home in Easley

Charming 2-bedroom home in Easley

Easley

9.2 out of 10, Wonderful, (5 reviews)

9.2/10

Wonderful

(5 reviews)

"comfortable home near everything. very pretty yard, beautiful screened back porch. "

adrienne m.

The price is CA $186

CA $186

CA $268 total

includes taxes & fees

Sep 5 - Sep 6

Charming 2-bedroom home in Easley

A covered outdoor seating area with a table and chairs, surrounded by a wooden deck and railing.

A kitchen with wooden cabinets, stainless steel appliances, a clock, and a window with blinds.

A cabin-style building with a wooden exterior, large windows, and a view of the water.

A cozy cabin interior with a dining area, sofa, kitchen, and a ceiling fan.

18. 2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing

2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing

Anderson

10.0 out of 10, Exceptional, (3 reviews)

10/10

Exceptional

(3 reviews)

"The place was beautiful and immaculate. It was perfect for our family of 3. Loved that we could see the lake from the porch."

Lisa B.

The price is CA $217

CA $217

CA $477 total

includes taxes & fees

Sep 7 - Sep 8

2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing

A modern kitchen with dark cabinets, stainless steel appliances, and a tiled backsplash.

A living room with a grey sofa, a wooden floor, and framed botanical prints on the wall.

An aerial view of a campus with multiple buildings, parking lots, and green spaces.

A living room with a sofa, a television, a fireplace, and a dining area.

19. Sunny Side Cottage: Cozy Stay by Anderson U!

Sunny Side Cottage: Cozy Stay by Anderson U!

Anderson

9.8 out of 10, Exceptional, (30 reviews)

9.8/10

Exceptional

(30 reviews)

"The accommodations were adequate and the location was excellent."

Pat

The price is CA $143

CA $143

CA $535 total

includes taxes & fees

Sep 9 - Sep 10

Sunny Side Cottage: Cozy Stay by Anderson U!

A wooden deck with a railing overlooking a forested area during sunset.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a dining table with chairs, and a chandelier.

A bedroom with a wooden bed, a ceiling fan, a window with a view of trees, and a mirror on the wall.

A living room with a fireplace, a sofa, a coffee table, and a TV.

20. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson

Seneca

9.8 out of 10, Exceptional, (15 reviews)

9.8/10

Exceptional

(15 reviews)

"We enjoyed our stay. Had everything we needed. "

Diane S.

The price is CA $338

CA $338

CA $728 total

includes taxes & fees

Sep 7 - Sep 8

Waterfront 3br home on Lake Hartwell near Clemson

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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