Title: Book The Best Hotels in Sikeston, MO for 2026 from CA $99 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Sikeston](https://expedia.ca/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0/corn-maze-fall-farm-family-friendly-outdoor-activity.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Sikeston, MO from CA $99 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Sikeston Pool [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=POOL) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=CABIN) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=PETS) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=HOT_TUB) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&travelerType=family_friendly) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=WATER_PARK) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=APARTMENT) ## Check prices for these dates Tonight [Jan 9 - Jan 10](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 10 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Sikeston hotels ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1,005 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $125 CA $141 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/59c49f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/05842f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,001 reviews) "Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen CA $97 CA $110 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "Great place. Friendly staff clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff CA $125 CA $143 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (685 reviews) "Conveniently located, clean, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip CA $117 CA $126 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,008 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $93 CA $106 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (728 reviews) "Clean room and easy access to room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne CA $77 CA $88 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature)](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/182edc95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,002 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex CA $132 CA $149 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/a2f06e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/d0c3544f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/945fac08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "Very clean, very friendly! We will be staying again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth CA $104 CA $120 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Refrigerator & Microwave (2 Rooms, Tub)](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/0f190cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,001 reviews) "Awesome stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breckin CA $125 CA $141 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/44b66206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (690 reviews) "The room was clean and nice. The breakfast was really good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kalani CA $83 CA $93 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/c7d69739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (477 reviews) "Very nice hotel within walking distance to many good restaurants " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $173 CA $196 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/006e0795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,002 reviews) "Staff great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $97 CA $109 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1,002 reviews) "Breakfast was great- staff was welcoming. Will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura CA $115 CA $122 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (148 reviews) "Lovely staff clean hotel comfortable beds " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kastriot CA $122 CA $138 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jackpot Suite | Living area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (487 reviews) " Excellent stay. Will come again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joydeep CA $123 CA $139 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/eea0b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/d5132360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/2812fc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Dexter [](https://www.expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) Dexter 7.6/10 Good (390 reviews) "Clean room, friendly staff and quiet stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margo CA $110 CA $124 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (445 reviews) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney CA $146 CA $165 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/432f7137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (460 reviews) "Very clean and super friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine CA $139 CA $157 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn By Hilton Dexter [](https://www.expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) Dexter 10/10 Exceptional (6 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $147 CA $165 total includes taxes & fees Jan 17 - Jan 18 [](https://www.expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (104 reviews) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $124 CA $141 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-24&endDate=2026-01-25®ionId=6058766&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Sikeston, MO Showing deals for:**Jan 23 - Jan 25** ### Image gallery for TownePlace Suites by Marriott Sikeston ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### TownePlace Suites by Marriott Sikeston Sikeston **9.2/10**Wonderful (11 reviews) 15% off CA $176 CA $399 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=111247452&adults=2) ### Image gallery for The Riverview ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Riverview Cape Girardeau **9.4/10**Exceptional (487 reviews) 10% off CA $297 CA $670 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=105081384&adults=2) ### Image gallery for Charming Secluded Getaway Cabin within minutes of amenities ![Interior](https://images.trvl-media.com/lodging/76000000/75900000/75891500/75891457/0c802aa2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Charming Secluded Getaway Cabin within minutes of amenities Cape girardeau **10/10**Exceptional (18 reviews) 5% off CA $205 CA $652 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=75891457&adults=2) ### Image gallery for Charming 3-bedroom house in delightful Advance with AC, WiFi ![Exterior detail](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/a162857d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Charming 3-bedroom house in delightful Advance with AC, WiFi Advance **10/10**Exceptional (5 reviews) 5% off CA $214 CA $620 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=103362449&adults=2) ### Image gallery for Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO ![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/e90509fa.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Cape Girardeau **9.6/10**Exceptional (47 reviews) 5% off CA $157 CA $405 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=71736900&adults=2) ### Image gallery for Urban 2-bedroom Escape in Downtown Cape Girardeau ![Exterior detail](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/23d7d447.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Urban 2-bedroom Escape in Downtown Cape Girardeau Cape Girardeau **10/10**Exceptional (9 reviews) 5% off CA $231 CA $651 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=109929505&adults=2) ### Image gallery for Charming 3-bedroom house near downtown ![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/b1eb2df2_edited_275e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Charming 3-bedroom house near downtown Cape Girardeau **10/10**Exceptional (2 reviews) 5% off CA $205 CA $766 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=107909366&adults=2) ### Image gallery for Little Blue Cottage on Spanish ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Little Blue Cottage on Spanish Cape Girardeau **8.6/10**Excellent (48 reviews) 5% off CA $119 CA $269 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-01-23&endDate=2026-01-25&selected=45712431&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels.d6058766.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels.d6058766.Travel-Guide-Hotels) ## Sikeston and related destinations - Sikeston - Florence - Los Banos - Lima Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August. [See all hotels in Sikeston](https://www.expedia.ca/Hotel-Search?startDate=2026-01-24&endDate=2026-01-25&adults=2®ionId=6058766) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ### Stay near popular Sikeston attractions [](https://expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels) #### Sikeston Depot Museum You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6305602) [](https://expedia.ca/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels) #### Central Park Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6305608) ## More cheap stays in Sikeston ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO CA $87 CA $99 total Jan 12 - Jan 13 includes taxes & fees 7.2/10 Good! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St Cape Girardeau MO CA $97 CA $109 total Jan 14 - Jan 15 includes taxes & fees 8.8/10 Excellent! (1,005 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO CA $97 CA $110 total Jan 14 - Jan 15 includes taxes & fees 9/10 Wonderful! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Candlewood Suites Cape Girardeau by IHG 485 S Mount Auburn Rd Cape Girardeau MO CA $111 CA $133 total Jan 12 - Jan 13 includes taxes & fees 8/10 Very Good! (889 reviews) [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO CA $132 CA $149 total Jan 25 - Jan 26 includes taxes & fees 9.4/10 Exceptional! (1,001 reviews) [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO CA $139 CA $157 total Feb 8 - Feb 9 includes taxes & fees 8.8/10 Excellent! (459 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ## Hotels in Sikeston with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 3 properties [](https://expedia.ca/4Star-Sikeston-Hotels.s40-0-d6058766.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 15 properties [](https://expedia.ca/3Star-Sikeston-Hotels.s30-0-d6058766.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 67 properties [](https://expedia.ca/2Star-Sikeston-Hotels.s20-0-d6058766.Travel-Guide-Filter-Hotels) ## Find out more about Sikeston ### Top reasons to visit Sikeston - **Outdoor Adventures:** Sikeston is perfect for outdoor enthusiasts, offering recreational areas for picnics and nature walks. - **Cultural Exploration:** Immerse yourself in local culture by visiting art museums and historic houses. - **Family-Friendly Activities:** Enjoy various activities suitable for families, ensuring a fun experience for all ages. - **Charming Downtown:** Explore the historic downtown filled with friendly locals and unique shops. - **Convenient Accommodations:** Choose from budget-friendly hotels with essential amenities for a comfortable stay. ### Find great hotels in Sikeston Explore a variety of hotel accommodations in Sikeston, Missouri, where you'll find budget-friendly options ranging from 2 to 3 stars. Whether you're travelling with family, on business, or bringing your furry friend along, Sikeston offers hotels tailored to your needs. Enjoy a comfortable stay with essential amenities and discover the best lodging options to make your visit memorable. - **[Days Inn and Suites by Wyndham Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)** Located in the heart of Sikeston, Days Inn and Suites offers a comfortable retreat for both leisure and business travellers. With a distinct Pet-Friendly theme, this hotel welcomes furry companions while providing essential business amenities like multiple meeting rooms. Guests can enjoy conveniences such as free Wi-Fi and a relaxing environment, making it ideal for those who need to mix work with pleasure. The pet policy includes restrictions but allows dogs and cats, ensuring every member of the family can join the trip. - **[Pear Tree Inn Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)** Pear Tree Inn is a family-oriented hotel that combines comfort with modern amenities. Perfect for those travelling with children, this property features complimentary cribs and a welcoming atmosphere for pets. Business travellers will appreciate the dedicated business centre, while families can enjoy spacious rooms designed for relaxation. With a focus on both family and pet-friendly experiences, this hotel ensures that everyone feels at home, making it an excellent choice for a memorable stay in Sikeston. - **[Best Western Plus Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)** Best Western Plus Sikeston stands out for its strong emphasis on pet-friendly accommodations. This hotel allows pets and offers a welcoming environment for those travelling with their furry friends. Guests can take advantage of the comfortable rooms and convenient amenities, including a complimentary breakfast. With a commitment to providing a pleasant stay, this hotel is an excellent option for pet owners seeking both comfort and practicality in Sikeston. ### Where to stay in Sikeston Sikeston, Missouri, offers a delightful blend of outdoor adventures and charming scenery, perfect for romantic getaways or family-friendly vacations. Explore the historic downtown, where friendly locals create a warm atmosphere. Just a short drive away, discover nearby Mississippi County and its inviting neighbourhoods, ideal for budget-friendly excursions. Whether you're seeking a vibrant city vibe or tranquil retreats, Sikeston and its surroundings promise memorable experiences for every traveller. - **[Miner:](https://www.expedia.ca/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels)** Nestled in the Sikeston region, Miner is a charming village that offers a delightful blend of outdoor activities and family-friendly experiences. While visitor numbers tend to peak in January and during the summer months, the village remains a welcoming destination year-round. Outdoor enthusiasts will enjoy the scenic beauty and recreational areas nearby, including a national state park and a tranquil lake. With convenient access to shopping centres and local stores, Miner is an ideal spot for families seeking a memorable getaway. - **[Morehouse:](https://www.expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels)** Situated a mere 9.7km from Sikeston, Morehouse is a quaint city that promises a relaxed travel experience. Although it doesn't have distinct seasonal fluctuations in visitor numbers, the summer months—particularly from June to August—see a notable influx of tourists. Morehouse is perfect for those looking to explore a close-knit community with a blend of local charm and accessibility to nearby attractions, making it a great addition to your travel itinerary. - **[Bertrand:](https://www.expedia.ca/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels)** Located 12.9km from Sikeston, Bertrand is a vibrant city known for its outdoor adventures and family experiences. With visitor numbers peaking in January, April, and August, it offers a welcoming atmosphere throughout the year. Nature lovers can explore nearby landmarks such as a visitor centre, serene lakes, and nature reserves, providing plenty of opportunities for hiking and wildlife observation. Bertrand is an excellent choice for visitors looking to immerse themselves in nature while enjoying the warmth of a small-town community. ### Things to do in Sikeston Sikeston, Missouri, offers a delightful blend of outdoor activities and scenic beauty perfect for a romantic getaway. Tourists can enjoy the recreational area for picnics, visit the local casino for some entertainment, and explore the arena facility for various events. Whether you're looking to relax in nature or engage in lively activities, Sikeston has something to offer everyone. **Shopping** The Book Bug is a charming store in Sikeston, perfect for unique gifts and souvenirs. If you're up for a drive, consider visiting the nearby Richmond Mall for a wider selection of shops, including clothing and home decor stores. **Recreation** Experience the scenic [Boot Heel Golf Club](https://www.expedia.ca/Boot-Heel-Golf-Club-Hotels.0-l6305606-0.Travel-Guide-Filter-Hotels) for a round of golf amidst beautiful landscapes, perfect for outdoor enthusiasts. For ultimate relaxation, visit [eDen Spa & Salon](https://www.expedia.ca/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels), where you can indulge in rejuvenating body treatments, ideal for unwinding after a day of exploration. **Nightlife** A night in Sikeston offers a blend of excitement and relaxation. Visit the [Isle Casino Cape Girardeau](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels), located 48.3km away, for a vibrant experience filled with gaming and city vibes. Enjoy the romantic atmosphere as you try your luck and indulge in delicious dining options. ### Booking tips and Expedia advantages for Sikeston To save money during your trip to Sikeston, consider visiting between November and January when hotel prices are lower, especially on Tuesdays. Avoid Saturdays for the best rates. Opt for economical transportation methods like walking or biking, as the city is quite compact. When booking, use Expedia’s search tool to compare hotel deals and consider bundling your accommodations with flights for additional savings. Finally, take advantage of free activities in the area to enhance your experience without stretching your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and the type of hotel you’re looking for. To uncover the best prices and deals, be sure to sort the price filter from lowest to highest. - **Consider bundling your trip:** You can potentially save money by combining your Sikeston hotel reservation with your flights and activities through an Expedia package. ### Find the best attractions in Sikeston Sikeston, Missouri, is perfect for outdoor enthusiasts and those seeking romantic getaways, featuring attractions such as event venues, art museums, and historic houses. Visitors can immerse themselves in local culture while enjoying family-friendly activities. For a well-rounded experience, explore nearby attractions and consider staying at hotels close to the Sikeston Depot Museum for added convenience. - **[Sikeston Depot Museum:](https://www.expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)** Immerse yourself in the rich culture of Sikeston at this art museum, which showcases local history and art. The museum's unique exhibits and charming atmosphere provide a fascinating glimpse into the region’s heritage. - **[Central Park:](https://www.expedia.ca/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels)** A perfect spot for families, Central Park offers expansive green spaces and recreational facilities. Enjoy outdoor activities like picnicking or leisurely strolls, all while soaking in the vibrant city vibes of Sikeston. - **[Front Street Studio & Art Gallery:](https://www.expedia.ca/Front-Street-Studio-Art-Gallery-Hotels.0-l553248621532655753-0.Travel-Guide-Filter-Hotels)** Located 14.5km away, this art gallery features an array of local artworks, creating a cultural haven. The gallery's inviting ambience encourages creativity and appreciation for the arts. ### Best time to go to Sikeston Visitor numbers in Sikeston is generally unchanged in popularity throughout the year. The best time to visit Sikeston is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 36.0°F (2.2°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | February | 39.2°F (4.0°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | March | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average | | April | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 77.2°F (25.1°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | July | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 77.5°F (25.3°C) | Light Rain | Mostly Sunny | Slightly High | Average | | September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Average | Average | | October | 60.8°F (16.0°C) | Light Rain | Mostly Sunny | Average | Average | | November | 48.6°F (9.2°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 41.2°F (5.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Sikeston To visit Sikeston, Missouri, you can fly into several nearby airports. Paducah, KY (PAH-Barkley Regional) is located 75.6km away, with hotel options like [The Respite Bed and Breakfast](https://www.expedia.ca/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information), [Harrah's Metropolis Hotel & Casino](https://www.expedia.ca/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information), and [The 1857](https://www.expedia.ca/Paducah-Hotels-The-1857.h15338500.Hotel-Information). Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 38.6km from Sikeston, offering accommodations such as Drury Plaza Hotel, Drury Inn & Suites, and Courtyard by Marriott. Another option is Cairo, IL (CIR-Cairo Regional), also 38.6km away, where you can find Quality Inn Cairo, Super 8 by Wyndham, and [Eagle Inn Charleston](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information). Each airport provides convenient access to various lodging choices for your stay. ## Recent reviews of Sikeston hotels ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 5/5 Excellent "All the above!" A verified traveller stayed at Drury Inn & Suites Cape Girardeau Posted 3 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 5/5 Excellent "Clean and comfy room. Great staff" A verified traveller stayed at Pear Tree Inn Sikeston Posted 3 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 5/5 Excellent "Room was very spacious, clean and well equipped Breakfast was good, staff was great and they had a great little mini store " A verified traveller stayed at Hampton Inn Sikeston Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 5/5 Excellent "Staff was very helpful and room was very clean. " A verified traveller stayed at Courtyard by Marriott Cape Girardeau Downtown Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg) ### Super 8 by Wyndham Sikeston/Miner Area 5/5 Excellent "Stayed with my kids for visitation " A verified traveller stayed at Super 8 by Wyndham Sikeston/Miner Area Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 5/5 Excellent "We enjoyed the cleanliness of the room, the Christmas decorations, and the location." A verified traveller stayed at Candlewood Suites Cape Girardeau by IHG Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 5/5 Excellent "Warm lights in rooms and hall ways would be great, currently white (day) lights everywhere" A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Posted 5 days ago [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 5/5 Excellent "Great value." A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 5/5 Excellent "Staff promptly fixed a problem, room smelled very clean." A verified traveller stayed at Fairfield Inn & Suites by Marriott Sikeston Posted 7 days ago [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Sikeston? > For couples planning a romantic retreat, the nearby parks provide an ideal setting for leisurely strolls and picnics, allowing you to unwind together amidst nature. The local dining scene is also superb for intimate dinners, showcasing everything from classic Southern comfort food to unique culinary experiences. > > > Families will find Miner particularly accommodating, with spacious lodging options and nearby family-friendly activities. The proximity to attractions like the Sikeston Depot Museum and the local parks ensures that there's something for everyone to enjoy, making it easy to create lasting memories together. ### What are the best hotels in Sikeston that travellers recommend? ### What are the best family hotels in Sikeston? ### What hotels in Sikeston offer free breakfast? ### What are the top pet-friendly hotels in Sikeston? ### What are the best budget hotels in Sikeston? > Another excellent option is the Drury Inn & Suites Sikeston, also boasting a customer review rating of 9.4\. This hotel features an array of amenities, including both indoor and outdoor pools, and a delicious buffet breakfast that is free for all guests. Families will find value in the spacious rooms equipped with sofa beds, as well as the free long-distance calls and WiFi, making it easy to stay connected during your travels. > > > For travellers, the [Hampton Inn Sikeston](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information), rated 8.8, offers a cozy atmosphere with an accessible fitness centre and a welcoming indoor pool. This hotel is superb for couples seeking a comfortable retreat while still enjoying the convenience of complimentary breakfasts and free WiFi. > > > Whether you're traveling with family or as a couple, Sikeston has budget-friendly hotels that cater to your needs while ensuring a pleasant stay. View all [budget hotels in Sikeston](https://www.expedia.ca/sikeston-hotels-cheap-hotels.0-0-d6058766-tcheaphotels.travel-guide-filter-hotels). ### When is the best time to go to Sikeston? > As you plan your visit, you'll find that peak tourist activity occurs from May through August. This bustling season is ideal for those who enjoy vibrant community events, such as the famous Sikeston Rodeo, which showcases local talent and offers a fantastic atmosphere. With plenty of sunshine and comfortable weather, you can easily indulge in outdoor adventures, from hiking in nearby parks to enjoying leisurely walks around the charming downtown area. > > > For families and couples seeking a memorable experience, late spring is particularly appealing. The local cuisine shines during this time, with various food festivals and farmers' markets showcasing the region's delicious Southern fare. You can savour unique dishes while mingling with friendly locals, making for a truly immersive experience. > > > If you're considering a visit during a less busy time, early November presents a good opportunity. 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