Photo by Ryan Coleman

Find hotels in Sikeston, MO from CA $75

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check Sikeston hotel prices

Tomorrow night
Next weekend

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top 10 Sikeston hotels and places to stay

Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1002)
"Easy access of the highway in a very safe and convenient location. Newer hotel and staff was excellent. The included dinner and breakfast was an unexpected surprise and didn’t disappoint. "
The price is CA $135
CA $154 total
includes taxes & fees
May 19 - May 20
Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1003)
"So glad I found the Pear Tree Inn. Clean room and a comfortable bed and the staff were wonderful!"
The price is CA $129
CA $148 total
includes taxes & fees
May 16 - May 17
Pear Tree Inn Sikeston
Hampton Inn Sikeston
2.5 star property
9.0 out of 10, Wonderful, (265)
"Great place and very clean and friendly staff!"
The price is CA $168
CA $191 total
includes taxes & fees
May 19 - May 20
Hampton Inn Sikeston
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (340)
"Went for the eclipse and paid an outrageous price but otherwise a very nice hotel "
The price is CA $168
CA $190 total
includes taxes & fees
May 19 - May 20
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
8.6 out of 10, Excellent, (15)
"The old house was charming. It could benefit from a really good, deep clean. The bathrooms and beds/linens were very clean and the kitchen was functional. We didn't use the outdoor area but it was nice and well suited to a comfortable place to hang out on a nice day. The town has food and necessity shopping available and easily accessible. Overall we were pleased with our overnight stay. "
The price is CA $122
CA $269 total
includes taxes & fees
May 20 - May 21
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
Travel Inn & Suites
2.5 star property
8.4 out of 10, Very good, (521)
"Rooms a little small. "
The price is CA $100
CA $114 total
includes taxes & fees
May 13 - May 14
Travel Inn & Suites
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very good, (1003)
"It was hard to find. No prominant sign. Otherwise ok."
The price is CA $138
CA $156 total
includes taxes & fees
May 19 - May 20
Best Western Plus Sikeston
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very good, (194)
"The best value for money I have ever had. Exceptional service and cleanliness. My room was fantastic. Huge and spotless. Theres an elevator and they are pet friendly. I travel a great deal and this was the best. Good breakfast with lots of choices, including healthy choices. Safe area right next to a McDonalds and a Burger King, but not 24hr ones so it was quiet at night. "
The price is CA $126
CA $143 total
includes taxes & fees
May 19 - May 20
Comfort Inn & Suites Sikeston I-55
Travelodge by Wyndham Dexter
2.0 star property
7.4 out of 10, Good, (320)
"Nice clean room "
The price is CA $127
CA $143 total
includes taxes & fees
May 27 - May 28
Travelodge by Wyndham Dexter
Country Yard Inn and Suite
2.0 star property
7.4 out of 10, Good, (31)
"Considering the price of the room, it was adequate. Thankfully it was a cooler weekend (the previous week had been uncharacteristically warm) or we would have had to move rooms due to an inadequate air conditioning unit. That being said, it was a clean room and the bed was comfortable. The motel is convenient to the interstate and the main road into Sikeston. Our room was at the far end of the motel, so away from any interstate noise."
The price is CA $79
CA $90 total
includes taxes & fees
May 24 - May 25
Country Yard Inn and Suite
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.0 out of 10, Good, (1002)
"The staff was very friendly but once we got to the room, there was blood on the top sheet and hair in the shower. We were only there for a quick sleep on a long road trip so I didn’t bother telling anyone. Just pulled off the comforter and slept on the sheets. "
The price is CA $96
CA $109 total
includes taxes & fees
May 27 - May 28
Days Inn and Suites by Wyndham Sikeston
Dexter Inn
2.5 star property
6.8 out of 10, (236)
"A good, not-too-busy spot to stay in the vicinity of the total eclipse track the night before."
The price is CA $81
CA $92 total
includes taxes & fees
Jun 3 - Jun 4
Dexter Inn
Econo Lodge Dexter
2.0 star property
6.6 out of 10, (184)
"Excellent staff "
The price is CA $84
CA $95 total
includes taxes & fees
May 18 - May 19
Econo Lodge Dexter
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.4 out of 10, (470)
"It was by the outlet store"
The price is CA $83
CA $94 total
includes taxes & fees
May 19 - May 20
Super 8 by Wyndham Sikeston/Miner Area
Hickory House Inn
2.5 star property
5.6 out of 10, (95)
"This hotel needs major remodeling! I probably wouldn’t stay there again. We traveled to watch theTotal Solar Eclipse in Dexter, MO. It was the cheapest place to stay in the area at the time. I would not recommend this place. "
The price is CA $75
CA $84 total
includes taxes & fees
May 13 - May 14
Hickory House Inn
Modern and Cozy Apartment with large windows and sunlight.
Modern and Cozy Apartment with large windows and sunlight.
Don't see what you're looking for?
See all available properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More cheap stays in Sikeston

Hotels near Popular Sikeston Attractions

Sikeston Travel Info

Number of hotels
281
Highest price
CA $168
Lowest price
CA $75
Known attractions
Sikeston Depot Museum, Central Park and The Book Bug
Hotels with indoor pools
5
Hotels with pools
5

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Notting Hill Cottage: This vacation home rental outside of Sikeston offers a patio, a private yard, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a spa tub. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Kids of all ages will also enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best pet-friendly accommodation in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What's the best hotel for a golf vacation in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some accommodations with pools in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel with an indoor pool, an outdoor pool, and free buffet breakfast. Other choices with an onsite pool include Best Western Plus Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel. View all hotels with pools in Sikeston.

Recent Reviews in Sikeston
Expedia verified reviews