- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Mission District hotels

1. Hotel Riu Plaza Fisherman's Wharf
Hotel Riu Plaza Fisherman's WharfFisherman's Wharf, 5.4 km from Mission District
9.0 out of 10, Wonderful, (7,749 reviews)
The price is CA $183
CA $274 total
includes taxes & fees
Nov 30 - Dec 1

2. Holiday Inn Golden Gateway by IHG
Holiday Inn Golden Gateway by IHGNob Hill, 3.4 km from Mission District
9.0 out of 10, Wonderful, (6,491 reviews)
The price is CA $170
CA $200 total
includes taxes & fees
Nov 29 - Nov 30

3. Hilton San Francisco Union Square
Hilton San Francisco Union SquareUnion Square, 3 km from Mission District
8.6 out of 10, Excellent, (1,907 reviews)
The price is CA $244
CA $288 total
includes taxes & fees
Nov 29 - Nov 30

4. Handlery Union Square Hotel
Handlery Union Square HotelUnion Square, 3.2 km from Mission District
8.8 out of 10, Excellent, (3,727 reviews)
The price is CA $213
CA $251 total
includes taxes & fees
Nov 22 - Nov 23

5. Parc 55 San Francisco - A Hilton Hotel
Parc 55 San Francisco - A Hilton HotelUnion Square, 2.9 km from Mission District
8.8 out of 10, Excellent, (1,740 reviews)
The price is CA $209
CA $246 total
includes taxes & fees
Nov 29 - Nov 30

6. The Marker Union Square San Francisco
The Marker Union Square San Francisco3.1 km from Mission District
9.2 out of 10, Wonderful, (1,637 reviews)
The price is CA $199
CA $234 total
includes taxes & fees
Nov 26 - Nov 27

7. FOUND Hotel Carlton, Nob Hill
FOUND Hotel Carlton, Nob Hill3.2 km from Mission District
8.6 out of 10, Excellent, (2,050 reviews)
The price is CA $103
CA $121 total
includes taxes & fees
Dec 2 - Dec 3

8. Hotel Nikko San Francisco
Hotel Nikko San FranciscoUnion Square, 3 km from Mission District
9.4 out of 10, Exceptional, (3,207 reviews)
The price is CA $253
CA $364 total
includes taxes & fees
Nov 22 - Nov 23

9. Club Quarters Hotel Embarcadero, San Francisco
Club Quarters Hotel Embarcadero, San FranciscoFinancial District, 4.2 km from Mission District
8.8 out of 10, Excellent, (3,562 reviews)
The price is CA $151
CA $178 total
includes taxes & fees
Nov 21 - Nov 22

10. Hilton San Francisco Financial District
Hilton San Francisco Financial DistrictFinancial District, 4.1 km from Mission District
8.8 out of 10, Excellent, (3,446 reviews)
The price is CA $133
CA $157 total
includes taxes & fees
Nov 29 - Nov 30

11. Chancellor Hotel on Union Square
Chancellor Hotel on Union Square3.3 km from Mission District
9.4 out of 10, Exceptional, (3,580 reviews)
The price is CA $147
CA $174 total
includes taxes & fees
Nov 22 - Nov 23

12. LUMA Hotel San Francisco
LUMA Hotel San Francisco2.9 km from Mission District
9.6 out of 10, Exceptional, (2,673 reviews)
The price is CA $307
CA $361 total
includes taxes & fees
Nov 23 - Nov 24

13. Hotel Julian
Hotel Julian3.3 km from Mission District
8.8 out of 10, Excellent, (1,321 reviews)
The price is CA $159
CA $188 total
includes taxes & fees
Dec 13 - Dec 14

14. Hyatt Regency San Francisco
Hyatt Regency San FranciscoFinancial District, 4.3 km from Mission District
9.4 out of 10, Exceptional, (2,581 reviews)
The price is CA $241
CA $350 total
includes taxes & fees
Nov 20 - Nov 21

15. Hyatt Place San Francisco Downtown
Hyatt Place San Francisco Downtown3 km from Mission District
9.4 out of 10, Exceptional, (2,371 reviews)
The price is CA $243
CA $286 total
includes taxes & fees
Nov 22 - Nov 23

16. Hotel Zephyr San Francisco
Hotel Zephyr San FranciscoFisherman's Wharf, 5.4 km from Mission District
8.6 out of 10, Excellent, (2,933 reviews)
The price is CA $165
CA $253 total
includes taxes & fees
Dec 15 - Dec 16

17. Hotel Zoe Fisherman's Wharf
Hotel Zoe Fisherman's WharfFisherman's Wharf, 5.2 km from Mission District
9.2 out of 10, Wonderful, (2,361 reviews)
The price is CA $165
CA $264 total
includes taxes & fees
Dec 13 - Dec 14

18. Marriott Vacation Club®, San Francisco
Marriott Vacation Club®, San FranciscoFisherman's Wharf, 5.1 km from Mission District
9.2 out of 10, Wonderful, (1,555 reviews)
The price is CA $217
CA $255 total
includes taxes & fees
Dec 14 - Dec 15

19. Hotel Caza Fisherman´s Wharf
Hotel Caza Fisherman´s WharfFisherman's Wharf, 5.2 km from Mission District
9.0 out of 10, Wonderful, (3,625 reviews)
The price is CA $174
CA $273 total
includes taxes & fees
Dec 4 - Dec 5

20. The Pickwick Hotel
The Pickwick HotelSouth of Market, 2.8 km from Mission District
7.8 out of 10, Good, (1,642 reviews)
The price is CA $131
CA $154 total
includes taxes & fees
Nov 22 - Nov 23
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Mission District
Where to stay in Mission District
Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Learn more about Mission District

Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman's Wharf
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Top Mission District Hotel Reviews

Parker Guest House San Francisco
Parker Guest House San FranciscoMission District




















































































































