Mission District

San Francisco

A vibrant mural on a building, depicting a large figure with a heart-shaped halo, surrounded by various characters in colorful attire.
A busy street with a colorful building, a traffic light, and pedestrians.
A colorful mural on a building, a narrow street with pedestrians, and houses with vibrant facades.
A street lined with trees and buildings, including a mural and a sign for 'PIZZA COFFEE'.
A tree-lined street with historic buildings and parked cars.

Stay near popular Mission District attractions

A park with people sitting on the grass, a school building, and a cityscape in the background.

Mission Dolores Park

9.4/10 (3 reviews)
Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.
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Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

CA $68
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

CA $136
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
de Young Museum General Admission Ticket

de Young Museum General Admission Ticket

CA $35
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

CA $80
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
San Francisco: One day Yosemite and Giant Sequoia Tour

San Francisco: One day Yosemite and Giant Sequoias Tour

CA $285
per adult
90% of travellers recommend
San Francisco: One day Yosemite and Giant Sequoias Tour
Bridge 2 Bridge Tour: Golden Gate Bridge to Bay Bridge

San Francisco Bridge to Bridge Cruise (90-minutes)

CA $66
per adult
94% of travellers recommend
San Francisco Bridge to Bridge Cruise (90-minutes)
See all activities in San Francisco

Mission District Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is CA $235 per night from Sep 20 to Sep 21
CA $235
CA $277 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is CA $223 per night from Sep 24 to Sep 25
CA $223
CA $320 total
Sep 24 - Sep 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,659 reviews)
"Breakfast was excellent but room had smell and noise on ac unit."

Reviewed on Sep 16, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is CA $195 per night from Oct 16 to Oct 17
CA $195
CA $230 total
Oct 16 - Oct 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Handlery Union Square Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is CA $207 per night from Sep 18 to Sep 19
CA $207
CA $244 total
Sep 18 - Sep 19
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
The price is CA $199 per night from Sep 20 to Sep 21
CA $199
CA $235 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...
9.4/10 Exceptional! (3,456 reviews)
"The hotel is in an excellent location just a few steps from Union Square, the cable car stop, and the BART train station, not to mention all the clothing stores and food options around it. The room was clean and very comfortable with a refrigerator inside, and I really liked the free cookies, apples, ..."

Reviewed on Sep 16, 2026

Chancellor Hotel on Union Square
Grand Hyatt San Francisco

Grand Hyatt San Francisco

4 out of 5
345 Stockton St San Francisco CA
The price is CA $217 per night from Oct 2 to Oct 3
CA $217
CA $321 total
Oct 2 - Oct 3
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,013 reviews)
"Very nice hotel! Right in Union Square. Beds were very hard and pillows kind of sucked. But overall the rooms were nice and very clean. We were on the 29th floor which was a cool view Parking is horrible and because we have a bigger truck they couldn’t valet it and had no idea how to help us and ..."

Reviewed on Sep 15, 2026

Grand Hyatt San Francisco
See all 4,474 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Learn more about Mission District
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.
A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.
A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.
A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Oracle Park and San Francisco Bay are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.
A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Mission District

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