Mission District Vacation Packages

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  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Price found within the past 48 hours. Click for updated prices.
  • 55-inch TV with digital channels, pay movies
    Jul 9 - Jul 16

    The Clift Royal Sonesta San Francisco + Flight

    Union Square
    7 nights
    4.0 star property
    9.2/10 - Wonderful (1,451 reviews)
    "10/10 overall"
    Reviewed May 17, 2026
    Roundtrip • Edmonton (YEG) - San Francisco (SFO)
    YEG - SFO • 1 stop SFO - YEG • 1 stop
    CA $1,884
    CA $1,299
    per traveller
    found 1 day ago
    The Clift Royal Sonesta San Francisco
  • Deluxe Room, 2 Double Beds
    Jul 24 - Aug 4

    The Grove Inn + Flight

    Western Addition
    11 nights
    3.0 star property
    9.2/10 - Wonderful (712 reviews)
    "Cute Inn. Comfortable. Keep in mind no parking. That is a challenge moving car. They have coffee and tea. Small frig. Great shower pressure. Comfy bed. "
    Reviewed May 14, 2026
    Roundtrip • Kitchener (YKF) - San Francisco (SFO)
    YKF - SFO • 2 stops SFO - YYZ • 2 stops
    CA $4,144
    CA $2,563
    per traveller
    found 1 day ago
    The Grove Inn
  • Dining room
    Jul 24 - Aug 4

    Treehouse Hotel Silicon Valley + Flight

    Sunnyvale
    11 nights
    5.0 star property
    9.8/10 - Exceptional (93 reviews)
    "Staff, food, and stay were great! "
    Reviewed May 19, 2026
    Roundtrip • Kitchener (YKF) - San Francisco (SFO)
    YKF - SFO • 2 stops SFO - YYZ • 2 stops
    CA $6,170
    CA $3,873
    per traveller
    found 1 day ago
    Treehouse Hotel Silicon Valley
  • TV, iPod dock, pay movies
    Jul 9 - Jul 16

    The Huntington Hotel + Flight

    Downtown San Francisco
    7 nights
    5.0 star property
    9.0/10 - Wonderful (16 reviews)
    "Great rooms. Perfect location. Beautiful hotel overall. Wish we had more time at the property. We'd love to stay again."
    Reviewed April 27, 2026
    Roundtrip • Edmonton (YEG) - San Francisco (SFO)
    YEG - SFO • 1 stop SFO - YEG • 1 stop
    CA $4,956
    CA $3,274
    per traveller
    found 1 day ago
    The Huntington Hotel
  • Restaurant
    Jul 24 - Aug 4

    The Westin St. Francis San Francisco on Union Square + Flight

    Union Square
    11 nights
    4.5 star property
    8.8/10 - Excellent (2,353 reviews)
    "The staff were amazing! They greet you every time they see you! They address us by our names which was nice! The room was comfortable and spacious. Shopping within walking distance of the hotel. The Bourbon Steak bar was amazing drinks were on point. Then we decided to eat at the restaurant I definitely look forward to coming back. The only thing I didn’t like was they charge $100 a night to park at the hotel although we were staying there."
    Reviewed May 17, 2026
    Roundtrip • Kitchener (YKF) - San Francisco (SFO)
    YKF - SFO • 2 stops SFO - YYZ • 2 stops
    CA $2,765
    CA $1,884
    per traveller
    found 1 day ago
    The Westin St. Francis San Francisco on Union Square

Mission District Hotel Deals

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $199 per night from May 25 to May 26
CA $199
CA $291 total
May 25 - May 26
includes taxes & fees
9/10 Wonderful! (7,478 reviews)
"Great location"

Reviewed on May 19, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $187 per night from May 31 to Jun 1
CA $187
CA $220 total
May 31 - Jun 1
includes taxes & fees
8.8/10 Excellent! (2,782 reviews)
"FOR THE AMOUNT OF MONEY SPENT HERE IM APPALLED THE WAY WE WERE TREATED. SECURITY AT OUR DOOR 5 TIMES BEFORE 10:45PM. MY FINACE AND I WERE VISITING SF FOR A PRE WEDDING GETAWAY WITH NO KIDS. HIM AND I ALONE. ASIDE FROM THE FACT I HAVE A VERY ASSERTIVE VOICE THERE IS ABSOLUTLEY NO REASON SECURITY AND ..."

Reviewed on May 18, 2026

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $186 per night from May 25 to May 26
CA $186
CA $219 total
May 25 - May 26
includes taxes & fees
9/10 Wonderful! (5,767 reviews)
"We love the location"

Reviewed on May 18, 2026

Holiday Inn Golden Gateway by IHG
See all 4,514 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Mission District vacation package cost?
Our Mission District packages, which begin at just , are an awesome way to save big. Pick your favorite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District vacation package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your vacation your own way. We offer more than 550 partner airlines and 1,000,000 hotels worldwide, so that everyone has a chance to travel and live out those vacation dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cozy Dolores Park Condo By Redawning. Both will make you feel at home and are favorites among lots of travelers.
How far in advance should I book my Mission District vacation?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District vacation deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including vacation rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia vacation package?
With a vacation package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District vacation package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District vacation package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Discover the most popular places to visit in Mission District

Mission Dolores Park

Mission Dolores Park

Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.

Mission Dolores Park
Mission San Francisco de Asís

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the notable monuments and shops in this vibrant area.

Mission San Francisco de Asís

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

CA $67
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz Visit with Night Option and SF Bay Cruise

Alcatraz Visit with Night Option and SF Bay Cruise

CA $171
per adult
94% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

CA $149
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.