Mission District Vacation Packages

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Top Holiday Package Deals in Mission District

Price found within the past 48 hours. Click for updated prices.
Embassy Hotel

Embassy Hotel

2.5 out of 5
Downtown San Francisco
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to San Francisco (SFO)
6.8/10 (189 reviews)
Very basic, don’t expect much. The paint on the walls is peeling, we could smell the rug, there was a bit of mold in the bathroom and gnats coming out of the shower’s drain. The bed was old and after a couple of days gave us a back pain. Very noisy outside and area is not safe to be out alone at night.

Reviewed on Jul. 27, 2025

The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

4.5 out of 5
Union Square
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to San Francisco (SFO)
8.8/10 Excellent! (2,559 reviews)
Great location & great price! Staff is wonderful!

Reviewed on Aug. 3, 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to San Francisco (SFO)
9.2/10 Wonderful! (428 reviews)
Loved this property. Upgraded our room with a fantastic view of the water. Very walkable. Hotel car Audi was wonderful perk to drive us to dinner. Very eco friendly. Great breakfast! We reserved rooftop tubs-worth every penny. Complete luxury with beautiful rooftop view. Can’t wait to come back:)

Reviewed on Aug. 3, 2025

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to San Francisco (SFO)
9/10 Wonderful! (6,602 reviews)
Beds were wonderful. Breakfast was good. I would have liked more options for creamers. Both nights we were awakened by people on….something screaming Outside our windows. Many very loud cars. Probably would ask for a different room next time. Bell service was great. Desk ladies were quite rude.

Reviewed on Aug. 4, 2025

The Donatello

The Donatello

3.5 out of 5
Union Square
per person
Sep 24 - Sep 28
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to San Francisco (SFO)
9.2/10 Wonderful! (1,000 reviews)
Everyone there very friendly very welcoming. Definitely will go back.

Reviewed on Jul. 31, 2025

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

1 out of top 10 points of interest in this area
4/5(6 area reviews)

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Find hotels in Fisherman's Wharf

Mission District Hotel Deals

Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd, Burlingame, CA
Fully refundable
The price is CA $145 per night from Aug 17 to Aug 18
CA $145
CA $165 total
Aug 17 - Aug 18
includes taxes & fees
7.6/10 Good! (1,985 reviews)
"The room was extra roomy for the area."

Reviewed on Aug. 4, 2025

Crowne Plaza San Francisco Airport by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from Aug 24 to Aug 25
CA $175
CA $205 total
Aug 24 - Aug 25
includes taxes & fees
8.6/10 Excellent! (1,576 reviews)
"Great location. Walking distance to chinatown, financial district and little Italy. My room location was a little noisy. It was located right beside/behind the elevators. I can hear rumbling noise, I thought at first I was near a train station but realized it must be the elevators."

Reviewed on Aug. 2, 2025

Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $182 per night from Aug 26 to Aug 27
CA $182
CA $271 total
Aug 26 - Aug 27
includes taxes & fees
8.8/10 Excellent! (6,619 reviews)
"Very nice hotel near Pier 39!!"

Reviewed on Aug. 1, 2025

Hotel Riu Plaza Fisherman's Wharf
See all 4,693 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
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Beach Vacations
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Family Vacations

Frequently asked questions

How much does a Mission District vacation package cost?
Our Mission District packages, which begin at just CA $453, are an awesome way to save big. Pick your favorite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District vacation package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your vacation your own way. We offer more than 550 partner airlines and 1,000,000 hotels worldwide, so that everyone has a chance to travel and live out those vacation dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cozy Dolores Park Condo By Redawning. Both will make you feel at home and are favorites among lots of travelers.
How far in advance should I book my Mission District vacation?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District vacation deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including vacation rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia vacation package?
With a vacation package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District vacation package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District vacation package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Discover the most popular places to visit in Mission District

Mission Dolores Park

Mission Dolores Park

Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.

Mission Dolores Park
Mission San Francisco de Asís

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the notable monuments and shops in this vibrant area.

Mission San Francisco de Asís

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

CA $75
per adult
84% of travellers recommend
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

CA $143
per adult
86% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
Visit de Young Museum in Golden Gate Park

de Young Museum General Admission Ticket

CA $27
per adult
de Young Museum General Admission Ticket
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.