A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

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Recommended hotels in Puxico

1. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.6 out of 10, Exceptional, (82 reviews)
"This place is Brand new and really great!"
United States
Bryan
The price is CA $137
CA $155 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn By Hilton Dexter

2. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean, great food, excellent staff."
United States
Dean
The price is CA $126
CA $142 total
includes taxes & fees
Nov 13 - Nov 14
Drury Inn & Suites Poplar Bluff

3. Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (288 reviews)
"The place was okay for a night"
United States
Herman
The price is CA $71
CA $81 total
includes taxes & fees
Dec 4 - Dec 5
Econo Lodge Dexter

4. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,008 reviews)
"Everything was great about the stay!"
United States
Denise
The price is CA $125
CA $140 total
includes taxes & fees
Dec 6 - Dec 7
Hampton Inn Poplar Bluff

5. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (424 reviews)
"Staff was very friendly"
United States
Steven
The price is CA $123
CA $140 total
includes taxes & fees
Nov 15 - Nov 16
Travelodge by Wyndham Dexter

6. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (976 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
The price is CA $136
CA $153 total
includes taxes & fees
Nov 15 - Nov 16
Fairfield Inn & Suites by Marriott Poplar Bluff

7. Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (373 reviews)
"breakfast was good, staff friendly, pool area needs work"
United States
Edward
The price is CA $90
CA $102 total
includes taxes & fees
Dec 5 - Dec 6
Dexter Inn

8. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,000 reviews)
"Rooms were large and clean. Bathroom was large with a nice shower. Parking was convenient Would definitely stay again."
United States
Jim
The price is CA $99
CA $111 total
includes taxes & fees
Nov 9 - Nov 10
Motel 6 Poplar Bluff, MO

9. OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (147 reviews)
"Great staff! Clean rooms and convinient"
United States
DIEGO
The price is CA $71
CA $88 total
includes taxes & fees
Dec 5 - Dec 6
OYO Hickory House Inn

10. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (804 reviews)
"Always an enjoyable stay"
United States
Nathan
The price is CA $111
CA $125 total
includes taxes & fees
Dec 5 - Dec 6
Holiday Inn Poplar Bluff by IHG

11. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (444 reviews)
"Excellent every things"
United States
Muhammad
The price is CA $100
CA $113 total
includes taxes & fees
Dec 6 - Dec 7
Comfort Inn Poplar Bluff North

12. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (679 reviews)
"I stay here quite often when I come into town, most the time room is clean and fresh, this time the room had a urine smell, the bed needed repair or replaced, there was an issue with expedia and I got charged twice but expedia did refund the money. Overall disappointed with this stay and will start staying at the drury from now on."
United States
Michael
The price is CA $94
CA $106 total
includes taxes & fees
Nov 12 - Nov 13
Super 8 by Wyndham Poplar Bluff Missouri

13. Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
8.0 out of 10, Very good, (1 review)
"The coffee pot looked like it hadn't been used for a while. Bathrooms and beds were very nice."
United States
Donna M.
The price is CA $184
CA $333 total
includes taxes & fees
Nov 9 - Nov 10
Hunting / Fishing Cabin at Lake Wappapello

14. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
10.0 out of 10, Exceptional, (4 reviews)
"Perfect place for our stay on the way to North Carolina! Clean, cozy and convenient!"
United States
Robert G.
The price is CA $196
CA $229 total
includes taxes & fees
Nov 10 - Nov 11
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

15. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (39 reviews)
"Overall, it was a good experience. I would stay again."
United States
Tammy G.
The price is CA $150
CA $288 total
includes taxes & fees
Nov 10 - Nov 11
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

16. Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided

Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided
Greenville
10.0 out of 10, Exceptional, (13 reviews)
"Cute, cozy, private getaway that you won't want to leave!"
United States
Jade G.
The price is CA $250
CA $383 total
includes taxes & fees
Nov 9 - Nov 10
Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided

17. Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
8.4 out of 10, Very good, (7 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is CA $126
CA $133 total
includes taxes & fees
Nov 9 - Nov 10
Lake Wappapello

18. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is CA $147
CA $160 total
includes taxes & fees
Dec 3 - Dec 4
EC Reed's Mercantile and Hotel

19. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
9.0 out of 10, Wonderful, (18 reviews)
"Very clean, well stocked kitchen with necessities. We enjoyed our stay!"
United States
Melissa W.
The price is CA $161
CA $383 total
includes taxes & fees
Nov 9 - Nov 10
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Puxico Hotel Reviews

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Puxico RV Parks information

Number of reviews
3,633
Accommodation
0 RV Parks
Lowest Price
CA $81
Highest Price
CA $383

Frequently asked questions

What makes RV parks in Puxico unique?
If you're planning an RV adventure to Puxico, staying in an RV park is a great way to see the area. After you've settled in at the RV park in Puxico, get out into nature and make it a memorable trip.
Where should I park my RV around Puxico?
Based on our travel knowledge, Wanderers End Sanctuary Forest Farm & Village Co-op is a top choice for your Puxico adventure.
What should I see in Puxico?
If you want to find some ways to explore Puxico while making good use of your travel budget, this destination has lots to offer. Spots where you'll find the natural beauty on display include Mark Twain National Forest. Another place not to be missed is Mingo Wilderness.
What's it like to stay in an RV park in Puxico?
Reserving a spot in an RV park is a fun and budget-friendly alternative for your road trip to Puxico. This kind of accommodation offers you a roomy space to park your RV and stay overnight where you're often surrounded by nature. Lots of RV parks are located close to lakes and hiking spots, which makes it convenient to get out and enjoy nature.

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